The Korean Journal of Parasitology (KJP)

A potential role of protein extractions from Metagonimus yokogawai in amelionating inflammation in patients with ankylosing spondylitis

Eun Jeong Won, Yu Jeong Lee, Moon-Ju Kim, Hae-In Lee, Hyun Hee Jang, Seong Hoon Kim, Hee Min Yoo, Namki Cho, Seung Cheol Shim, Tae-Jong Kim

Experimental Parasitology.2024; 259: 108718. CrossRef

Helminth-derived proteins as immune system regulators: a systematic review of their promise in alleviating colitis

Maimonah Alghanmi, Faisal Minshawi, Tarfa A. Altorki, Ayat Zawawi, Isra Alsaady, Abdallah Y Naser, Hassan Alwafi, Soa’ad M. Alsulami, Ala A. Azhari, Anwar M Hashem, Rowa Alhabbab

Protection from T cell-dependent colitis by the helminth-derived immunomodulatory mimic of transforming growth factor-β,Hp-TGM

Danielle J Smyth, Madeleine P J White, Chris J C Johnston, Anne-Marie Donachie, Marta Campillo Poveda, Henry J McSorley, Rick M Maizels

Discovery Immunology.2023;[Epub] CrossRef

Bioinformatics analysis and prokaryotic expression of a cystatin analogue from Spirometra erinaceieuropaei

Lin Huang, Ling Mai, Gang Lv, Xinjun Chen

Biotechnology & Biotechnological Equipment.2023;[Epub] CrossRef

Potential of human helminth therapy for resolution of inflammatory bowel disease: The future ahead

Experimental Parasitology.2022; 232: 108189. CrossRef

Parasitomimetics: Can We Utilize Parasite-Derived Immunomodulatory Molecules for Interventions to Immunological Disorders?

Frontiers in Immunology.2022;[Epub] CrossRef

Molecular Characteristics and Potent Immunomodulatory Activity of Fasciola hepatica Cystatin

Kai Zhang, Yucheng Liu, Guowu Zhang, Xifeng Wang, Zhiyuan Li, Yunxia Shang, Chengcheng Ning, Chunhui Ji, Xuepeng Cai, Xianzhu Xia, Jun Qiao, Qingling Meng

The Korean Journal of Parasitology.2022; 60(2): 117. CrossRef

Cysteine protease of Clonorchis sinensis alleviates DSS-induced colitis in mice

Xiaoying Xie, Zhanshuai Wu, Yuhong Wu, Jing Liu, Xinyuan Chen, Xiaoqian Shi, Caiheng Wei, Jiasheng Li, Jiahui Lv, Qing Li, Lili Tang, Shanshan He, Tingzheng Zhan, Zeli Tang, John Pius Dalton

PLOS Neglected Tropical Diseases.2022; 16(9): e0010774. CrossRef

Clonorchis sinensis-Derived Protein Attenuates Inflammation and New Bone Formation in Ankylosing Spondylitis

Yu Jeong Lee, Moon-Ju Kim, Sungsin Jo, So-Hee Jin, Pu-Reum Park, Kijeong Park, Ho-Chun Song, Jahae Kim, Ji-Young Kim, Seung Cheol Shim, Tae-Hwan Kim, Sung-Jong Hong, Hyundeok Kang, Tae-Jong Kim, Eun Jeong Won

Frontiers in Immunology.2021;[Epub] CrossRef

Helminth-derived cystatins: the immunomodulatory properties of an Ascaris lumbricoides cystatin

Luis Caraballo, Josefina Zakzuk, Nathalie Acevedo

Parasitology.2021; 148(14): 1744. CrossRef

Effect of cysteine peptidase inhibitor of Eudiplozoon nipponicum (Monogenea) on cytokine expression of macrophages in vitro

Jana Ilgová, Lenka Kavanová, Katarína Matiašková, Jiří Salát, Martin Kašný

Molecular and Biochemical Parasitology.2020; 235: 111248. CrossRef

Amelioration of type 1 diabetes by recombinant fructose-1,6-bisphosphate aldolase and cystatin derived from Schistosoma japonicum in a murine model

Ke Yan, Bo Wang, Huabang Zhou, Qingli Luo, Jilong Shen, Yunxia Xu, Zhengrong Zhong

Parasitology Research.2020; 119(1): 203. CrossRef

Wuchereria bancrofti macrophage migration inhibitory factor‐2 (rWbaMIF‐2) ameliorates experimental colitis

Shriram Ramani, Nikhil Chauhan, Vishal Khatri, Connie Vitali, Ramaswamy Kalyanasundaram

Parasite Immunology.2020;[Epub] CrossRef

Integrated omics profiling of dextran sodium sulfate-induced colitic mice supplemented with Wolfberry (Lycium barbarum)

Wanping Aw, Huijuan Jia, Weida Lyu, Shinji Fukuda, Masaru Tomita, Lila Otani, Hisanori Kato

npj Science of Food.2020;[Epub] CrossRef

Therapeutic efficacy of Schistosoma japonicum cystatin on sepsis-induced cardiomyopathy in a mouse model

Shifang Gao, Huihui Li, Hong Xie, Shili Wu, Yuan Yuan, Liang Chu, Siying Sun, Huijuan Yang, Lingqin Wu, Yongsheng Bai, Qiao Zhou, Xin Wang, Bin Zhan, Hu Cui, Xiaodi Yang

Parasites & Vectors.2020;[Epub] CrossRef

Inflammatory bowel diseases, the hygiene hypothesis and the other side of the microbiota: Parasites and fungi

Simona Panelli, Sara Epis, Lucia Cococcioni, Matteo Perini, Moira Paroni, Claudio Bandi, Lorenzo Drago, Gian Vincenzo Zuccotti

Pharmacological Research.2020; 159: 104962. CrossRef

Parasite Cystatin: Immunomodulatory Molecule with Therapeutic Activity against Immune Mediated Disorders

Vishal Khatri, Nikhil Chauhan, Ramaswamy Kalyanasundaram

What Can Parasites Tell Us About the Pathogenesis and Treatment of Asthma and Allergic Diseases

Sina Bohnacker, Fabiana Troisi, Marta de los Reyes Jiménez, Julia Esser-von Bieren

Frontiers in Immunology.2020;[Epub] CrossRef

Adoptive transfer of Trichinella spiralis-activated macrophages can ameliorate both Th1- and Th2-activated inflammation in murine models

Shin Ae Kang, Mi-Kyung Park, Sang Kyun Park, Jun Ho Choi, Da In Lee, So Myong Song, Hak Sun Yu

Scientific Reports.2019;[Epub] CrossRef

Molecular Characterization of a Dirofilaria immitis Cysteine Protease Inhibitor (Cystatin) and Its Possible Role in Filarial Immune Evasion

Xiaowei Dong, Jing Xu, Hongyu Song, Yuchen Liu, Maodi Wu, Haojie Zhang, Bo Jing, Weimin Lai, Xiaobin Gu, Yue Xie, Xuerong Peng, Guangyou Yang

Cystatin from Filarial Parasites Suppress the Clinical Symptoms and Pathology of Experimentally Induced Colitis in Mice by Inducing T-Regulatory Cells, B1-Cells, and Alternatively Activated Macrophages

Nalini Bisht, Vishal Khatri, Nikhil Chauhan, Ramaswamy Kalyanasundaram

SXP–RAL Family Filarial Protein, rWbL2, Prevents Development of DSS-Induced Acute Ulcerative Colitis

Namdev S. Togre, Priyanka S. Bhoj, Vishal K. Khatri, Aditya Tarnekar, Kalyan Goswami, Moreshwar R. Shende, M. V. R. Reddy

Indian Journal of Clinical Biochemistry.2018; 33(3): 282. CrossRef

Structural basis of the cystein protease inhibitor Clonorchis sinensis Stefin-1

So Young Park, Mi Suk Jeong, Seong Ah Park, Sung Chul Ha, Byoung-Kuk Na, Se Bok Jang

Biochemical and Biophysical Research Communications.2018; 498(1): 9. CrossRef

A Role for Epitope Networking in Immunomodulation by Helminths

Frontiers in Immunology.2018;[Epub] CrossRef

The Untapped Pharmacopeic Potential of Helminths

Trends in Parasitology.2018; 34(10): 828. CrossRef

The somatic proteins of Toxocara canis larvae and excretory-secretory products revealed by proteomics

Márcia B. da Silva, Juan R. Urrego A., Yisela Oviedo, Philip J. Cooper, Luis G.C. Pacheco, Carina S. Pinheiro, Fátima Ferreira, Peter Briza, Neuza M. Alcantara-Neves

Veterinary Parasitology.2018; 259: 25. CrossRef

Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules

Rick M. Maizels, Hermelijn H. Smits, Henry J. McSorley

Recombinant proteins of helminths with immunoregulatory properties and their possible therapeutic use

Leonardo Nascimento Santos, Luis Gustavo Carvalho Pacheco, Carina Silva Pinheiro, Neuza Maria Alcantara-Neves

A recombinant cystatin from Ascaris lumbricoides attenuates inflammation of DSS‐induced colitis

S. Coronado, L. Barrios, J. Zakzuk, R. Regino, V. Ahumada, L. Franco, Y. Ocampo, L. Caraballo

Parasite Immunology.2017;[Epub] CrossRef

Therapeutic effect of Schistosoma japonicum cystatin on bacterial sepsis in mice

Huihui Li, Shushu Wang, Bin Zhan, Wenxin He, Liang Chu, Dapeng Qiu, Nan Li, Yongkun Wan, Hui Zhang, Xingzhi Chen, Qiang Fang, Jilong Shen, Xiaodi Yang

Parasites & Vectors.2017;[Epub] CrossRef

Elevated expression of CST1 promotes breast cancer progression and predicts a poor prognosis

Da-nian Dai, Yan Li, Bo Chen, Yong Du, Shi-bing Li, Shi-xun Lu, Zhi-ping Zhao, Ai-jun Zhou, Ning Xue, Tian-liang Xia, Mu-sheng Zeng, Qian Zhong, Wei-dong Wei

Journal of Molecular Medicine.2017; 95(8): 873. CrossRef

Parasite-Derived Proteins for the Treatment of Allergies and Autoimmune Diseases

Zhenyu Wu, Lifu Wang, Yanlai Tang, Xi Sun

Frontiers in Microbiology.2017;[Epub] CrossRef

Helminths in the gastrointestinal tract as modulators of immunity and pathology

Fumi Varyani, John O. Fleming, Rick M. Maizels

American Journal of Physiology-Gastrointestinal and Liver Physiology.2017; 312(6): G537. CrossRef

Immuno-Modulatory Effect and Therapeutic Potential of Brugia malayi Cystatin in Experimentally Induced Arthritis

Ravi Shankar Prasad Yadav, Vishal Khatri, Nitin Amdare, Kalyan Goswami, V. B. Shivkumar, Nitin Gangane, Maryada Venkata Rami Reddy

Indian Journal of Clinical Biochemistry.2016; 31(2): 203. CrossRef

Therapeutic potential of recombinant cystatin from Schistosoma japonicum in TNBS-induced experimental colitis of mice

Shushu Wang, Yuanyuan Xie, Xiaodi Yang, Xuesong Wang, Ke Yan, Zhengrong Zhong, Xiaowei Wang, Yuanhong Xu, Yi Zhang, Fang Liu, Jilong Shen

Parasites & Vectors.2016;[Epub] CrossRef

Fernando Lopes, Chelsea Matisz, José L. Reyes, Humberto Jijon, Ahmed Al-Darmaki, Gilaad G. Kaplan, Derek M. McKay

Inflammatory Bowel Diseases.2016; 22(10): 2499. CrossRef

Unraveling the Hygiene Hypothesis of helminthes and autoimmunity: origins, pathophysiology, and clinical applications

Mathilde Versini, Pierre-Yves Jeandel, Tomer Bashi, Giorgia Bizzaro, Miri Blank, Yehuda Shoenfeld

TLR2‐dependent amelioration of allergic airway inflammation by parasitic nematode type II MIF in mice

M. K. Cho, M. K. Park, S. A. Kang, S. K. Park, J. H. Lyu, D.‐H. Kim, H.‐K. Park, H. S. Yu

Parasite Immunology.2015; 37(4): 180. CrossRef

Brugia malayi cystatin therapeutically ameliorates dextran sulfate sodium‐induced colitis in mice

Vishal Khatri, Nitin Amdare, Aaditya Tarnekar, Kalyan Goswami, Maryada Venkata Rami Reddy

Journal of Digestive Diseases.2015; 16(10): 585. CrossRef

Generating a detailed protein profile of Fasciola hepatica during the chronic stage of infection in cattle

Orçun Haçarız, Ahmet Tarık Baykal, Mete Akgün, Pınar Kavak, Mahmut Şamil Sağıroğlu, Gearóid Patrick Sayers

PROTEOMICS.2014; 14(12): 1519. CrossRef

Cloning, expression and characterisation of a type II cystatin from Schistosoma japonicum, which could regulate macrophage activation

Xiao Yang, Ju Liu, Yuan Yue, Wei Chen, Man Song, Ximei Zhan, Zhongkai Wu

Parasitology Research.2014; 113(11): 3985. CrossRef

Identification and characterization of the second cysteine protease inhibitor of Clonorchis sinensis (CsStefin-2)

Jung-Mi Kang, Hye-Lim Ju, Kon Ho Lee, Tong-Soo Kim, Jhang Ho Pak, Woon-Mok Sohn, Byoung-Kuk Na

Parasitology Research.2014; 113(1): 47. CrossRef

Disequilibrium of M1 and M2 Macrophages Correlates with the Development of Experimental Inflammatory Bowel Diseases

Wei Zhu, Jianbo Yu, Ying Nie, XueKui Shi, Yang Liu, Fujuan Li, Xiao-li Zhang

Immunological Investigations.2014; 43(7): 638. CrossRef

Of worms, mice and man: An overview of experimental and clinical helminth-based therapy for inflammatory bowel disease

Marthe Heylen, Nathalie E. Ruyssers, Els M. Gielis, Els Vanhomwegen, Paul A. Pelckmans, Tom G. Moreels, Joris G. De Man, Benedicte Y. De Winter

Pharmacology & Therapeutics.2014; 143(2): 153. CrossRef

Worm Proteins of Schistosoma mansoni Reduce the Severity of Experimental Chronic Colitis in Mice by Suppressing Colonic Proinflammatory Immune Responses

Marthe Heylen, Nathalie E. Ruyssers, Joris G. De Man, Jean-Pierre Timmermans, Paul A. Pelckmans, Tom G. Moreels, Benedicte Y. De Winter, Benoit Foligne

PLoS ONE.2014; 9(10): e110002. CrossRef

Immunomodulation by helminth parasites: Defining mechanisms and mediators

Henry J. McSorley, James P. Hewitson, Rick M. Maizels

International Journal for Parasitology.2013; 43(3-4): 301. CrossRef

Helminth Infections and Host Immune Regulation

Clinical Microbiology Reviews.2012; 25(4): 585. CrossRef