Parasites, Hosts and Diseases

"Amanallah Sarlak"

Original Article

Scolicidal Effects of Olea europaea and Satureja khuzestanica Extracts on Protoscolices of Hydatid Cysts: Mohammad Zibaei, Amanallah Sarlak, Bahram Delfan, Behrouz Ezatpour, Alireza Azargoon; Korean J Parasitol 2012;50(1):53-56.
Published online March 6, 2012; DOI: https://doi.org/10.3347/kjp.2012.50.1.53

Abstract
PDF

Treatment of hydatid disease is mainly surgical, with medical treatment being reserved as a coadjuvant treatment. Use of effective scolicidal agents during surgery of cystic echinococcosis is essential to reduce the recurrence rate. The goal of this study was to evaluate the in vitro scolicidal effects of hydroalcoholic extracts of Satureja khuzestanica leaves and aqueous extracts of Olea europaea leaves on hydatid cyst protoscolices. Echinococcus granulosus protoscolices were collected from the liver of sheep infected with the hydatid cyst. Various concentrations of plant extracts were used in different exposure times for viability assay of protoscolices. Among the olive leaf extracts tested, 0.1% and 0.01% concentrations had strong scolicidal effects in 120 min. S. khuzestanica 0.1% had very strong scolicidal effects in 30, 60, and 120 min of exposure times and the mortality rate decreased with the lower concentration. The finding have shown that the scolicidal activity of S. khuzestanica against cystic echinococosis protoscolices were more effective, while the O. europaea extract showed less effects.

Citations

Citations to this article as recorded by

In vitro protoscolicidal effects of Hypericum perforatum, Thymus vulgaris, Pimenta racemosa, and Mentha piperita against Echinococcus granulosus protoscoleces
R. Yildiz, A. H. Unlu
Helminthologia.2025; 62(2): 95. CrossRef
In Vitro Scolicidal Effect of Urtica dioica and Pyrus boissieriana Extracts Against Protoscoleces of Echinococcus granulosus
Kimia Goudarzi, Rasoul Alimi, Tandis Zarghami, Mohammad Saleh Bahreini, Mohamad Ghanimatdan, Meysam Sharifdini, Erfan Kohansal, Aref Teimouri
Shiraz E-Medical Journal.2024;[Epub] CrossRef
Effectiveness Evaluation of Viti’s vinifera Leaf Extract on the Viability of Echinococcus Eggs and Protoscolices In Vitro
Mohammed M. Mares, Saleh Al-Quraishy, Mutee Murshed
Veterinary Sciences.2023; 10(6): 400. CrossRef
Dispersion of TiO 2 and ZnO nanoparticles into the Costus arabicus L. root smoke for enhancing its antimicrobial, antioxidant and antiparasitic activities
Leila Mohammad Taghizadeh Kashani, Shiva Masoudi, Mohammad Mahdi Ahmadian-Attari
Inorganic and Nano-Metal Chemistry.2022; 52(2): 297. CrossRef
Is the Intraoperative Use of the Chlorhexidine Gluconate Safe for Inactivation of the Liver Hydatid Cyst?
Mohammad Eslamian, Mohsen Kolahdouzan, Hossein Yousofi Darani, Alireza Rezaei, Mohammad Hosein Sanei
Archives of Clinical Infectious Diseases.2022;[Epub] CrossRef
Herbal Medicines against Hydatid Disease: A Systematic Review (2000–2021)
Mughees Aizaz Alvi, Sadiq Khan, Rana Muhammad Athar Ali, Warda Qamar, Muhammad Saqib, Noman Yousaf Faridi, Li Li, Bao-Quan Fu, Hong-Bin Yan, Wan-Zhong Jia
Life.2022; 12(5): 676. CrossRef
The chemical composition and antibacterial activity of a methanolic extract of Satureja khuzistanica
Mansooreh Davoodi, Samad Nejad-Ebrahimi, Abdolhossein Rustaiyan, Davoud Esmaeili
Brazilian Journal of Pharmaceutical Sciences.2022;[Epub] CrossRef
Scolicidal effects of the Nicotiana tabacum L. extract at various concentrations and exposure times
Roya Latifi, Abbas Azadmehr, Sahar Mosalla, Kiarash Saleki, Reza Hajiaghaee
Journal of Medicinal Plants.2022; 21(82): 111. CrossRef
Scolicidal Activity of Eriobotrya japonica and Lonicera japonica Extracts Against Hydatid Cysts of Echinococcus granulosus
Chonoor Mohammadi, Jgarxwen Nuraddin, Suham Najmadin
Research Journal of Phytochemistry.2022; 16(2): 74. CrossRef
Scolicidal effects of Cassia fistula and Urtica dioica extracts on protoscoleces of hydatid cysts
Amirmehdi Sarvestani, Ali Karimian, Rasool Mohammadi, Kourosh Cheraghipour, Masoomeh Zivdri, Morteza Nourmohammadi, Mohammad Almasian, Amirhossein Nafari
Journal of Parasitic Diseases.2021; 45(1): 59. CrossRef
Integrative review on ethnobotany, essential oil, phytochemical, agronomy, molecular and pharmacological properties of Satureja species
Fatemeh Sefidkon, Zohreh Emami Bistgani
Journal of Essential Oil Research.2021; 33(2): 114. CrossRef
Silybum marianum ethanolic extract: in vitro effects on protoscolices of Echinococcus granulosus G1 strain with emphasis on other Iranian medicinal plants
Ali Taghipour, Fatemeh Ghaffarifar, John Horton, Abdolhossein Dalimi, Zohreh Sharifi
Tropical Medicine and Health.2021;[Epub] CrossRef
In vitro scolicidal effects of Sideritis perfoliata extract against Echinococcus granulosus
Tuncay Çelik, Muhittin Önderci, Mustafa Pehlivan, Önder Yumrutaş, Fatih Üçkardeş
International Journal of Clinical Practice.2021;[Epub] CrossRef
Antimicrobial Activities of Satureja khuzestanica Jamzad; A Review
Hossein Mahmoudvand, Behrouz Ezatpour, Leila Masoori, Abdolrazagh Marzban, Ali Moghaddam, Kiana Shahzamani, Vahid Malekara, Kourosh Cheraghipour
Infectious Disorders - Drug Targets .2021; 21(2): 161. CrossRef
Modern approaches to treatment of echinococcal diseases
R. S. Sultanova, R. T. Mejidov, S. M. Magomedova
Clinical Medicine (Russian Journal).2021; 99(5-6): 333. CrossRef
Treatment and prevention of the recurrence of liver echinococcosis
R. T. Mejidov, R. S. Sultanova
Grekov's Bulletin of Surgery.2020; 179(2): 26. CrossRef
Antioxidant and scolicidal activities of four Iranian Mentha species (Lamiaceae) in relation to phenolic elements
Mojtaba Ranjbar, Mahmoud Kiani, Ali Nikpay
Journal of Herbmed Pharmacology.2020; 9(3): 200. CrossRef
A systematic review of medicinal plants used against Echinococcus granulosus
Rehman Ali, Sanaullah Khan, Marina Khan, Muhammad Adnan, Ijaz Ali, Taj Ali Khan, Sumbal Haleem, Muhammad Rooman, Sadia Norin, Shahid Niaz Khan, Branislav T. Šiler
PLOS ONE.2020; 15(10): e0240456. CrossRef
The role of arbuscular mycorrhizal fungi on acclimatization of micropropagated plantlet Satureja khuzistanica Jam. by ameliorating of antioxidant activity and expression of PAL gene
Leila Mirjani, Azam Salimi, Mohammad Matinizadeh, Khadijeh Razavi, Maryam Shahbazi
Scientia Horticulturae.2019; 253: 364. CrossRef
In-vitro evaluation of Nigella sativa and Punica granatum effect on protoscolices of hydatid cysts
Nasr Moawad El-Bahy, Amer Ragheb Abdelaziz, Reda Elbastawisy Khalafalla
Revista Brasileira de Parasitologia Veterinária.2019; 28(2): 210. CrossRef
Progress in the pharmacological treatment of human cystic and alveolar echinococcosis: Compounds and therapeutic targets
Mar Siles-Lucas, Adriano Casulli, Roberto Cirilli, David Carmena, Giovanna Raso
PLOS Neglected Tropical Diseases.2018; 12(4): e0006422. CrossRef
Natural products applied against hydatid cyst protoscolices: A review of past to present
Mohammad Hasan Kohansal, Abbasali Nourian, Mohammad Taghi Rahimi, Ahmad Daryani, Adel Spotin, Ehsan Ahmadpour
Acta Tropica.2017; 176: 385. CrossRef
Scolicidal agents for protoscolices of Echinococcus granulosus hydatid cyst: Review of literature
Seyedeh Maryam Sharafi, Raheleh Rafiei Sefiddashti, Behnam Sanei, Morteza Yousefi, Hossein Yousofi Darani
Journal of Research in Medical Sciences.2017;[Epub] CrossRef
A pharmacological and phytochemical overview onSatureja
Bektas Tepe, Mustafa Cilkiz
Pharmaceutical Biology.2016; 54(3): 375. CrossRef
Antihydatic and immunomodulatory effects of Punica granatum peel aqueous extract in a murine model of echinococcosis
Moussa Labsi, Lila Khelifi, Dalila Mezioug, Imene Soufli, Chafia Touil-Boukoffa
Asian Pacific Journal of Tropical Medicine.2016; 9(3): 211. CrossRef
A Critical Overview on the Pharmacological and Clinical Aspects of Popular Satureja Species
Fereshteh Jafari, Fatemeh Ghavidel, Mohammad M. Zarshenas
Journal of Acupuncture and Meridian Studies.2016; 9(3): 118. CrossRef
In vitro effects of vinegar on protoscolices of hydatid cyst
Reza Hajihossein, Zahra Eslamirad, Mahdi Mosayebi, Reza Ghasemikhah, Mojtaba Didehdar
Asian Pacific Journal of Tropical Disease.2015; 5(3): 210. CrossRef
A new bioactive monoterpene–flavonoid from Satureja khuzistanica
Maryam Malmir, Ahmad Reza Gohari, Soodabeh Saeidnia, Olga Silva
Fitoterapia.2015; 105: 107. CrossRef
Diabetes mellitus and its management with medicinal plants: A perspective based on Iranian research
Arezou Rezaei, Azad Farzadfard, Atefe Amirahmadi, Maasoomeh Alemi, Mitra Khademi
Journal of Ethnopharmacology.2015; 175: 567. CrossRef
Identifying Effective Medicinal Plants for Cold in Lorestan Province, West of Iran
Bahram Delfan, Hamidreza Kazemeini, Mahmoud Bahmani
Journal of Evidence-Based Complementary & Alternative Medicine.2015; 20(3): 173. CrossRef
Scolicidal Effects of Black Cumin Seed (Nigella sativa) Essential Oil on Hydatid Cysts
Hossein Mahmoudvand, Ebrahim Saedi Dezaki, Farnaz Kheirandish, Behrouz Ezatpour, Sareh Jahanbakhsh, Majid Fasihi Harandi
The Korean Journal of Parasitology.2014; 52(6): 653. CrossRef
Characterization ofSatureja khuzestanicaLeaf as a Herbal Medicine
Maryam Malmir, Rita Serrano, Ahmad Reza Gohari, Olga Silva
Microscopy and Microanalysis.2014; 20(5): 1425. CrossRef