The information on mortality from echinococcosis is important not only for a better understanding of the severity of the disease, but also for evaluating the effectiveness of public health interventions. The aim of this research was to study the causes of mortality from echinococcosis. We have collected and analyzed the materials of 1,470 patients in 10 age - groups in the Republic of Armenia (from 2000 to 2016). To find out the causes of mortality from echinococcosis, we have analyzed the medical histories and protocols of postmortem examinations of 19 deaths from echinococcosis and 17 deaths due to other indirect causes not associated with the parasite. The average annual death rate from echinococcosis is 0.007 per 10,000 population, and the mortality is 1.29 (per 100 patients). The highest mortality occurs in people aged 70-79. Mortality from echinococcosis is also recorded among the unoperated children. The rupture of the parasitic cyst and hepatic insufficiency are major among the direct causes of mortality. Sometimes the hydatid cysts unrecognized during the life were first diagnosed at autopsy. Insufficient qualification of doctors in the field of helminthology, as well as the latent course of the disease or manifestation of minor symptoms in echinococcosis over a long period often led to medical errors. Further decline in mortality can be achieved by early diagnosis, timely hospitalization and treatment before the development of severe complications worsening the prognosis and outcomes of surgical intervention.
Citations
Citations to this article as recorded by
Narrowing the region of candidate genes that control the development of protoscoleces of Echinococcus multilocularis in the mouse liver Keisuke Sato, Naritaka Hikosaka, Hirokazu Kouguchi, Takao Irie, Masami Morimatsu, Takashi Agui Infection, Genetics and Evolution.2025; 127: 105704. CrossRef
Epidemiological profile and treatment of cystic echinococcosis hospitalized cases in Morocco between 2011 and 2021 Ilham Benmoujjane, Souad Bouhout, Aicha mehdioui, Houda Chebli, Meryem Zabarra, Mohammed Akrim, Hassan Chrifi, Touria Benamar Clinical Epidemiology and Global Health.2025; 33: 102035. CrossRef
A Rare Case of Hepatic Echinococcus granulosus Infection Diagnosed by Autopsy in Japan Akira Asai, Hisato Kawashima, Tomomi Hirota, Ryota Masutani, Shuichi Asano, Soo Ki Kim, Hiroki Nishikawa, Naomune Yamamoto Internal Medicine.2025;[Epub] CrossRef
Surgical treatment outcomes of hepatic cystic echinococcosis in HIV-positive and HIV-negative patients: a South African cohort study. Kate Couzens-Bohlin, Sanju Sobnach, Jake Krige, Urda Kotze, Christo Kloppers, Marc Bernon, Stefano Cacciatore, Eduard Jonas HPB.2025;[Epub] CrossRef
Assessment of Echinococcosis spp. Surveillance System through SWOT Analysis in Armenia A. H. Manukyan Medical Science of Armenia.2024; : 142. CrossRef
Complicated Liver Cystic Echinococcosis—A Comprehensive Literature Review and a Tale of Two Extreme Cases Valentin Calu, Octavian Enciu, Elena-Adelina Toma, Radu Pârvuleţu, Dumitru Cătălin Pîrîianu, Adrian Miron Tomography.2024; 10(6): 922. CrossRef
Unveiling the incidences and trends of the neglected zoonosis cystic echinococcosis in Europe: a systematic review from the MEmE project Adriano Casulli, Bernadette Abela-Ridder, Daniele Petrone, Massimo Fabiani, Branko Bobić, David Carmena, Barbara Šoba, Enver Zerem, Maria João Gargaté, Gordana Kuzmanovska, Cristian Calomfirescu, Iskra Rainova, Smaragda Sotiraki, Vera Lungu, Balázs Dezsén The Lancet Infectious Diseases.2023; 23(3): e95. CrossRef
α-Mangostin Exhibits a Therapeutic Effect on Spinal Cystic Echinococcosis by Affecting Glutamine Metabolism Sibo Wang, Haohao Sun, Shan Wang, Qian Ren, Yi Dai, Meipeng Zhu, Yayun Zhang, Honglei Kang, Jing Li, Jun Xiao, Yimin Dong, Weishan Wang Antimicrobial Agents and Chemotherapy.2023;[Epub] CrossRef
Endoscopic Endonasal Surgery for a Pterygopalatine Fossa Hydatid Cyst Vjerislav Peterković, Marcel Marjanović Kavanagh, Hrvoje Barić, Niko Njirić, Mirjana Balen-Topić, Relja Beck, Klaudija Višković Journal of Maxillofacial and Oral Surgery.2022; 21(1): 93. CrossRef
Status and prospect of novel treatment options toward alveolar and cystic echinococcosis Sibo Wang, Yibo Ma, Weishan Wang, Yi Dai, Haohao Sun, Jing Li, Shan Wang, Feng Li Acta Tropica.2022; 226: 106252. CrossRef
Mathematical modelling of echinococcosis in human, dogs and sheep with intervention Birhan Getachew Bitew, Justin Manango W. Munganga, Adamu Shitu Hassan Journal of Biological Dynamics.2022; 16(1): 439. CrossRef
Reasons for late diagnosis of pulmonary echinococcosis in a non-endemic area I. A. Krylova, S. N. Levitsky, I. A. Shabalina, A. V. Semenova, I. A. Turabov Translational Medicine.2022; 9(3): 81. CrossRef
Advances in research on echinococcoses epidemiology in China Mei-Hua Fu, Xu Wang, Shuai Han, Ya-Yi Guan, Robert Bergquist, Wei-Ping Wu Acta Tropica.2021; 219: 105921. CrossRef
Study on the effect of an ion channel inhibitor “Fluralaner” on Echinococcus granulosus protoscolices and metacestode layers in vitro Fatima Zahran, Hayam Mohamed Ezz El-Din, Mai Abdel Sameaa Shehata Journal of Parasitic Diseases.2020; 44(2): 411. CrossRef
A pilot comparative study between serological and genetic investigations in relationship to clinical outcomes on patients with cystic echinococcosis Nu. Altintas, S. A. Karamil, O. Turkum, M. Akil, A. Sakarya, H. Bozkaya, J. Šoltys, Na. Altintas Helminthologia.2020; 57(2): 91. CrossRef
Laparoscopic adrenal resection for primary echinococcosis A. A. Kovalev, Z. Kh. Osmanov, A. E. Neimark, I. N. Danilov Endoskopicheskaya khirurgiya.2018; 24(5): 51. CrossRef