Parasites, Hosts and Diseases

"Byeong-Kirl Baek"

Original Article

Persistent infection with Strongyloides venezuelensis in the Mongolian gerbil (Meriones unguiculatus): Byeong-Kirl Baek, In-Soo Whang, M. Khyrul Islam, Byeong-Soo Kim, Ibulaimu Kakoma; Korean J Parasitol 2002;40(4):181-186.
Published online December 30, 2002; DOI: https://doi.org/10.3347/kjp.2002.40.4.181

Abstract
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To examine the fate of Strongyloides venezuelensis, Mongolian gerbils (Meriones unguicalatus) were orally infected with 1,000 L₃ larvae per animal. Altogether, 50 gerbils divided into 5 groups of 10 each were monitored for a period of 570 days to document the kinetics of faecal egg output, adults worm population, morphological development, fecundity, and hematological changes including peripheral blood eosinophilia. This study chronicled a life long parasitism of S. venezuelensis in the gerbil host, and showed that S. venezuelensis infection was quite stable throughout the course of infection and the worms maintained their normal development as evidenced by their body dimension. A progressive loss of body condition of the infected gerbils was observed as the level of infection advanced. However, no detectable pathological changes were observed in the gastrointestinal tract. The present findings indicate that an immunocompetent host, such as the Mongolian gerbil, can serve as a life long carrier model of S. venezuelensis if the worms are not expelled within 570 days after infection.

Citations

Citations to this article as recorded by

Gastrointestinal effects of ivermectin treatment in rats infected with Strongyloides venezuelensis
Jalvita C. Mendonça, Loyane A. Gama, Andrieli T. Hauschildt, Luciana A. Corá, Madileine F. Américo
Acta Tropica.2019; 194: 69. CrossRef
Strongyloides ratti and S. venezuelensis – rodent models of Strongyloides infection
MARK VINEY, TAISEI KIKUCHI
Parasitology.2017; 144(3): 285. CrossRef
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Tegegn G. Jaleta, Christian Rödelsperger, Adrian Streit
Experimental Parasitology.2017; 180: 112. CrossRef
Callithrix penicillata as a nonhuman primate model for strongyloidiasis
Alan Lane de Melo, Vitor Luís Tenório Mati, Wanderlany Amâncio Martins
Primates.2012; 53(3): 303. CrossRef
Role of angiogenic factors in acute experimental Strongyloides venezuelensis infection
F. SHARIATI, J. L. PÉREZ-ARELLANO, J. LÓPEZ-ABÁN, A. M. EL BEHAIRY, A. MURO
Parasite Immunology.2010; 32(6): 430. CrossRef
Migration of Strongyloides venezuelensis in Rats after Oral Inoculation of Free-Living Infective Larvae
Kiku MATSUDA, Byeong-Su KIM, In-Soo WHANG, Chae-Woong LIM, Byeong-Kirl BAEK
Journal of Veterinary Medical Science.2003; 65(9): 971. CrossRef

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Brief Communication

Examination of gastrointestinal helminth in livestock grazing in grassland of Bangladesh: M. Motahar-Hussain Mondal, M-Khyrul Islam, Jin Hur, John-Hwa Lee, Byeong-Kirl Baek; Korean J Parasitol 2000;38(3):187-190.
Published online September 30, 2000; DOI: https://doi.org/10.3347/kjp.2000.38.3.187

Abstract
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To determine association of grassland with parasitic diseases of livestock in Bangladesh, the 'Tracer' animals (two cow calves and two goats) were released for a month in a grassland used for communal grazing of livestock near school premise in Kanthal, Trishal, Mymensingh, Bangladesh. After slaughtering of the tracer animals, their gastrointestinal tract examination revealed six species of nematode and one cestode. The nematode species were Haemonchus contortus, Trichostrongylus axei, Mecistocirrus digitatus, Oesophagostomum spp., Trichuris spp. and Bunostomum sp. The cestode was one of the genus Moniezia. With this preliminary study, grasslands are thought to be one of the main sources of gastrointestinal parasitic diseases of livestock in Bangladesh.

Citations

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Prevalence of gastrointestinal helminths infection in cattle based on breed, sex, age, location and management system
B.A. Koto, M.M. Adua, I.S. Musa, I. Mallam,
Agricultural Science and Technology.2025; 17(3): 58. CrossRef
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Aman Dev Moudgil, Lachhman Das Singla, M. P. Singh
Biological Rhythm Research.2020; 51(8): 1273. CrossRef
Gastro-intestinal nematodes in goats in Bangladesh: A large-scale epidemiological study on the prevalence and risk factors
Anita Rani Dey, Nurjahan Begum, Md. Abdul Alim, Subrota Malakar, Md. Taohidul Islam, Mohammad Zahangir Alam
Parasite Epidemiology and Control.2020; 9: e00146. CrossRef
Natural nodular worm infection in goats induces eosinophil extracellular DNA trap (EET) formation
Anisuzzaman, Abu Anas, Md. Golam Yasin, Sharmin Shahid Labony, Md. Mokbul Hossain, Nurjahan Begum, Takeshi Hatta, Naotoshi Tsuji, Md. Abdul Alim
Parasitology International.2020; 79: 102178. CrossRef
Infeksi parasit gastrointestinal pada kambing di Kupang
Aji Winarso
ARSHI Veterinary Letters.2018; 2(2): 25. CrossRef
Point prevalence of gastrointestinal helminthiasis in ruminants in southern Punjab, Pakistan
Muhammad Asif Raza, Zafar Iqbal, Abdul Jabbar, Muhammad Yaseen
Journal of Helminthology.2007; 81(3): 323. CrossRef

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Original Articles

Partial cross-resistance between Strongyloides venezuelensis and Nippostrongylus brasiliensis in rats: Byeong-Kirl Baek, M. Khyrul Islam, Jin-Ho Kim, John-Wha Lee, Jin Hur; Korean J Parasitol 1999;37(2):101-107.
Published online June 30, 1999; DOI: https://doi.org/10.3347/kjp.1999.37.2.101

Abstract
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Rats were immunized through an initial infection with 1,000 filariform larvae (L₃) of Nippostrongylus brasiliensis and after complete expulsion of worms they were challenged with 1,000 L₃ of Strongyloides venezuelensis to investigate whether cross-resistance developed against a heterologous parasite. Nippostrongylus brasiliensis-immunized rats developed a partial cross-resistance against S. venezuelensis migrating larvae (MSL₃) in the lungs and adult worms in the small intestine. The population of MSL₃ in the lungs were significantly lower (P<0.05) in immunized rats (22.0 ± 7.4) compared with controls (105.0 ± 27.6). The populations of adult worms, egg output and fecundity were initially decreased but from day 14 post-challenge they did not show any significant difference between immunized and control rats. However, the length of worm in immunized rat was revealed as retardation. Peripheral blood eosinophilia was significantly decreased (P<0.05) on day 7 post-challenge and then gradually increased, which peaked on day 42 post-challenge when most of the worms were expelled. These results suggest that peripheral blood eosinophilia is strongly involved in the worm establishment and expulsion mechanisms.

Citations

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Systemic Immune Modulation by Gastrointestinal Nematodes
Darshan N. Kasal, Lindsey M. Warner, Astra S. Bryant, Elia Tait Wojno, Jakob von Moltke
Annual Review of Immunology .2024; 42(1): 259. CrossRef
Intestinal helminth infection transforms the CD4+ T cell composition of the skin
Cajsa H. Classon, Muzhen Li, Ada Lerma Clavero, Junjie Ma, Xiaogang Feng, Christopher A. Tibbitt, Julian M. Stark, Rebeca Cardoso, Emma Ringqvist, Louis Boon, Eduardo J. Villablanca, Antonio Gigliotti Rothfuchs, Liv Eidsmo, Jonathan M. Coquet, Susanne Nyl
Mucosal Immunology.2022; 15(2): 257. CrossRef
Nematode-Infected Mice Acquire Resistance to Subsequent Infection With Unrelated Nematode by Inducing Highly Responsive Group 2 Innate Lymphoid Cells in the Lung
Koubun Yasuda, Takumi Adachi, Atsuhide Koida, Kenji Nakanishi
Frontiers in Immunology.2018;[Epub] CrossRef
Biotic and abiotic effects on the intestinal helminth community of the brown ratRattus norvegicusfrom Rio de Janeiro, Brazil
R.O. Simões, J.L. Luque, R. Gentile, M.C.S. Rosa, S. Costa-Neto, A. Maldonado
Journal of Helminthology.2016; 90(1): 21. CrossRef
Migratory route of Strongyloides venezuelensis in Lewis rats: Comparison of histological analyses and PCR
Nelson Mendes Marra, Fernanda Chiuso-Minicucci, Gabriel Capella Machado, Sofia Fernanda Gonçalves Zorzella-Pezavento, Thaís Graziela Donegá França, Larissa Lumi Watanabe Ishikawa, Alessandro F.T. Amarante, Alexandrina Sartori, Mônica R.V. Amarante
Experimental Parasitology.2011; 127(2): 334. CrossRef
Migration of Strongyloides venezuelensis in Rats after Oral Inoculation of Free-Living Infective Larvae
Kiku MATSUDA, Byeong-Su KIM, In-Soo WHANG, Chae-Woong LIM, Byeong-Kirl BAEK
Journal of Veterinary Medical Science.2003; 65(9): 971. CrossRef

8,294 View
52 Download
Crossref

Effects of in vitro culture methods on morphological development and infectivity of Strongyloides venezuelensis filariform larvae: M. Khyrul Islam, Kiku Matsuda, Jin-Ho Kim, Byeong-Kirl Baek; Korean J Parasitol 1999;37(1):13-19.
Published online March 31, 1999; DOI: https://doi.org/10.3347/kjp.1999.37.1.13

Abstract
PDF

The effects of in vitro culture methods on morphological development and infectivity of Strongyloides venezuelensis filariform larvae (L₃) to rats were investigated. A significantly higher body length was observed in L₃ from filter paper culture (597.3 ± 32.2 ?m) than those in fecal (509.9 ± 35.0 ?m) and nutrient broth culture (503.3 ± 31.0 ?m) (P<0.05). Larval infectivity was assessed by exposing rats to 1,000 L₃ from each culture and worms were recovered from the lungs and small intestines. Recovery rate of these worms did not show any significant difference. A significantly greater body length of adults was recorded in those corresponding to the L₃ harvested from filter paper (2,777.5 ± 204.4 ?m) and nutrient broth culture (2,732.5 ± 169.8 ?m) than those corresponding to the L₃ obtained from fecal culture (2,600.5 ± 172.4 ?m) (P<0.05). Although worm fecundity and EPG counts differed among culture methods but worm burdens and course of infection did not. These findings suggest that the methods of cultures have a significant effect on the morphological development of the larvae to the L₃ stage, but do not influence the infectivity to rats.

Citations

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Venestatin from parasitic helminths interferes with receptor for advanced glycation end products (RAGE)-mediated immune responses to promote larval migration
Daigo Tsubokawa, Taisei Kikuchi, Jae Man Lee, Takahiro Kusakabe, Yasuhiko Yamamoto, Haruhiko Maruyama, James B. Lok
PLOS Pathogens.2021; 17(6): e1009649. CrossRef
Strongyloides ratti and S. venezuelensis – rodent models of Strongyloides infection
MARK VINEY, TAISEI KIKUCHI
Parasitology.2017; 144(3): 285. CrossRef
Venestatin, a Ca ++ -binding protein from the parasitic nematode Strongyloides venezuelensis , is involved in the larval migration process
Daigo Tsubokawa, Takeshi Hatta, Taisei Kikuchi, Hiroki Maeda, Fusako Mikami, M. Abdul Alim, Haruhiko Maruyama, Naotoshi Tsuji
International Journal for Parasitology.2017; 47(8): 501. CrossRef
Viability of Strongyloides venezuelensis eggs and larvae in vermiculite containing the fungus Duddingtonia flagrans
Laryssa Pinheiro Costa Silva, Carolina Magri Ferraz, Anderson Rocha Aguiar, Jackson Victor Araújo, Steveen Rios Ribeiro, Débora Goldner Rossi, Luanderson Queiroz Mendes, Fausto Edmundo Lima Pereira, Narcisa Imaculada Brant Moreira, Fabio Ribeiro Braga
Parasitology Research.2017; 116(7): 2047. CrossRef
Development of free-living stages of Strongyloides ratti under different temperature conditions
Maki Sakamoto, Shoji Uga
Parasitology Research.2013; 112(12): 4009. CrossRef
Transcriptomic analysis of four developmental stages of Strongyloides venezuelensis
Eiji Nagayasu, Yoshitoshi Ogura, Takehiko Itoh, Ayako Yoshida, Gunimala Chakraborty, Tetsuya Hayashi, Haruhiko Maruyama
Parasitology International.2013; 62(1): 57. CrossRef
Characterization of the protective response against a homologous challenge infection with Strongyloides venezuelensis in rats
B.K Baek, M.K Islam, B.S Kim, C.W Lim, J Hur, A.O Oluoch, C.H Kim, I Kakoma
Veterinary Parasitology.2003; 113(3-4): 217. CrossRef
Persistent infection with Strongyloides venezuelensis in the Mongolian gerbil (Meriones unguiculatus)
Byeong-Kirl Baek, In-Soo Whang, M. Khyrul Islam, Byeong-Soo Kim, Ibulaimu Kakoma
The Korean Journal of Parasitology.2002; 40(4): 181. CrossRef
Partial cross-resistance between Strongyloides venezuelensis and Nippostrongylus brasiliensis in rats
Byeong-Kirl Baek, M. Khyrul Islam, Jin-Ho Kim, John-Wha Lee, Jin Hur
The Korean Journal of Parasitology.1999; 37(2): 101. CrossRef