Parasites, Hosts and Diseases

"Ekhlas Hamed Abdel-Hafeez"

Original Article

Breast-Feeding Protects Infantile Diarrhea Caused by Intestinal Protozoan Infections: Ekhlas Hamed Abdel-Hafeez, Usama Salah Belal, Manal Zaki Mohamed Abdellatif, Koji Naoi, Kazumi Norose; Korean J Parasitol 2013;51(5):519-524.
Published online October 31, 2013; DOI: https://doi.org/10.3347/kjp.2013.51.5.519

Abstract
PDF

This study investigated the effect of breast-feeding in protection against protozoan infection in infants with persistent diarrhea. Infants were classified into 2 groups; 161 breast-fed infants and the same number of non-breast-fed infants. Microscopic examinations of stool were done for detection of parasites and measuring the intensity of infection. Moreover, serum levels of IgE and TNF-α were measured by ELISA. Cryptosporidium spp., Entamoeba histolytica/Entamoeba dispar, Giardia lamblia, and Blastocystis sp. were demonstrated in infants with persistent diarrhea. The percentage of protozoan infections was significantly lower in breast-fed infants than that in the non-breast-fed infants. The levels of IgE and TNF-α were significantly lower in the breast-fed group than in the non-breast-fed group. There were significant positive associations between the serum levels of IgE and TNF-α and the intensity of parasite infection in the breast-fed group. It is suggested that breast-feeding has an attenuating effect on the rate and intensity of parasite infection.

Citations

Citations to this article as recorded by

Selected Protective Mechanisms of Human Milk Against Intestinal Protozoal Infections in Infants
Joanna Wróblewska, Anna Długosz, Marcin Wróblewski, Jarosław Nuszkiewicz, Paweł Sutkowy, Alina Woźniak
Current Issues in Molecular Biology.2025; 47(8): 674. CrossRef
Giardia lamblia risk factors and burden in children with acute gastroenteritis in a Nicaraguan birth cohort
Lester Gutiérrez, Nadja A. Vielot, Roberto Herrera, Yaoska Reyes, Christian Toval-Ruíz, Patricia Blandón, Rebecca J. Rubinstein, Javier Mora, Luther A. Bartelt, Filemón Bucardo, Sylvia Becker-Dreps, Samuel Vilchez, Sarman Singh
PLOS Neglected Tropical Diseases.2024; 18(11): e0012230. CrossRef
Tradeoffs in milk immunity affect infant infectious disease risk
Katherine Wander, Masako Fujita, Siobhan M Mattison, Margaret Duris, Megan Gauck, Tessa Hopt, Katherine Lacy, Angela Foligno, Rebecca Ulloa, Connor Dodge, Frida Mowo, Ireen Kiwelu, Blandina T Mmbaga
Evolution, Medicine, and Public Health.2022; 10(1): 295. CrossRef
Intestinal Parasitic Infections Among Pediatric Patients in a Metropolitan City of Bangladesh With Emphasis on Cryptosporidiosis
Nusrat Jahan Nipa, Nasima Aktar, Hasina M Hira, Farhana Akter, Dilshad Jahan, Salequl Islam, Ayukafangha Etando, Adnan Abdullah, Kona Chowdhury, Rahnuma Ahmad, Ahsanul Haq, Mainul Haque
Cureus.2022;[Epub] CrossRef
Association of genetic polymorphism at tumor necrosis factor-α gene promoter - 1031T/C and parasitic infections among children in Northern South Africa
N.C. Davhana, A.K. ElBakri, P.O. Bessong, A. Samie
Heliyon.2020; 6(10): e05129. CrossRef
Antibodies, prophylaxis, transmission
Pierre Lutgen
Pharmacy & Pharmacology International Journal.2018;[Epub] CrossRef
Parasiticidal effect of synthetic bovine lactoferrin peptides on the enteric parasite Giardia intestinalis
Hugo Aguilar-Diaz, Adrian Canizalez-Roman, Tomas Nepomuceno-Mejia, Francisco Gallardo-Vera, Yolanda Hornelas-Orozco, Kamran Nazmi, Jan G.M. Bolscher, Julio Cesar Carrero, Claudia Leon-Sicairos, Nidia Leon-Sicairos
Biochemistry and Cell Biology.2017; 95(1): 82. CrossRef
Cryptosporidium and Giardia in Africa: current and future challenges
Sylvia Afriyie Squire, Una Ryan
Parasites & Vectors.2017;[Epub] CrossRef
Cryptosporidium and Cyclospora Diarrheal Infection in Malnourished Children: a Nutritional Approach
María A. Echevarría, María L. Eva
Current Tropical Medicine Reports.2017; 4(3): 178. CrossRef
Molecular Analysis of the Enteric Protozoa Associated with Acute Diarrhea in Hospitalized Children
Sonia Boughattas, Jerzy M. Behnke, Khalid Al-Ansari, Aarti Sharma, Wafa Abu-Alainin, Asma Al-Thani, Marawan A. Abu-Madi
Frontiers in Cellular and Infection Microbiology.2017;[Epub] CrossRef
Killing of Cryptosporidium sporozoites by Lactoferrin
Jose Luis Paredes, Hayley Sparks, A. Clinton White Jr., Griselle Martinez-Traverso, Theresa Ochoa, Alejandro Castellanos-González
The American Journal of Tropical Medicine and Hygiene.2017; 97(3): 774. CrossRef
Role of Eosinophils and Tumor Necrosis Factor Alpha in Interleukin-25-Mediated Protection from Amebic Colitis
Zannatun Noor, Koji Watanabe, Mayuresh M. Abhyankar, Stacey L. Burgess, Erica L. Buonomo, Carrie A. Cowardin, William A. Petri, Alan Sher, Ralph Budd, Kris Chadee
mBio.2017;[Epub] CrossRef
Evolution of Socioeconomic Conditions and Its Relation to Spatial–Temporal Changes of Giardiasis and Helminthiasis in Amazonian Children
B. M. Delfino, R. G. Campos, T. M. Pereira, S. A. S. Mantovani, H. Oliart-Guzmán, A. C. Martins, A. M. Braña, F. L. C. C. Branco, J. A. Filgueira-Júnior, A. P. Santos, T. S. Araújo, C. S. M. Oliveira, A. A. Ramalho, P. T. Muniz, C. T. Codeço, M. da Silva-
EcoHealth.2016; 13(4): 743. CrossRef
The Impact of the Milk Glycobiome on the Neonate Gut Microbiota
Alline R. Pacheco, Daniela Barile, Mark A. Underwood, David A. Mills
Annual Review of Animal Biosciences.2015; 3(1): 419. CrossRef
Exclusive breast feeding in early infancy reduces the risk of inpatient admission for diarrhea and suspected pneumonia in rural Vietnam: a prospective cohort study
Sarah Hanieh, Tran T. Ha, Julie A. Simpson, Tran T. Thuy, Nguyen C. Khuong, Dang D. Thoang, Thach D. Tran, Tran Tuan, Jane Fisher, Beverley-Ann Biggs
BMC Public Health.2015;[Epub] CrossRef
Noninvasive intestinal amebiasis
Gayatri V. Nair, Easwaran P. Variyam
Current Opinion in Infectious Diseases.2014; 27(5): 465. CrossRef
Breastfeeding and risk of parasitic infection-a review
Prameela Kannan Kutty
Asian Pacific Journal of Tropical Biomedicine.2014; 4(11): 847. CrossRef