Human diphyllobothriasis is a widespread fish-borne zoonosis caused by the infection with broad tapeworms belonging to the genus Diphyllobothrium. In mainland China, so far 20 human cases of Diphyllobothrium infections have been reported, and the etiologic species were identified as D. latum and D. nihonkaiense based on morphological characteristics or molecular analysis. In the present study, proglottids of diphyllobothriid tapeworms from 3 human cases that occurred in Heilongjiang Province, China were identified as D. nihonkaiense by sequencing mitochondrial cytochrome c oxidase subunit I (cox1) and NADH dehydrogenase subunit 5 (nad5) genes. Two different cox1 gene sequences were obtained. One sequence showed 100% homology with those from humans in Japan. The remaining cox1 gene sequence and 2 different nad5 gene sequences obtained were not described previously, and might reflect endemic genetic characterizations. D. nihonkaiense might also be a major causative species of human diphyllobothriasis in China. Meanwhile, the finding of the first pediatric case of D. nihonkaiense infection in China suggests that infants infected with D. nihonkaiense should not be ignored.
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Dietary footprints of a global parasite: diagnosing Dibothriocephalus nihonkaiensis in non-endemic regions Wilson G.W. Goh, Jean-Marc Chavatte, Gabriel Z.R. Yan, Yuan Yi Constance Chen, Mark Dhinesh Muthiah, Lionel H.W. Lum Gut Pathogens.2025;[Epub] CrossRef
Identification of Dibothriocephalus nihonkaiensis plerocercoids from the autumn chum salmon Oncorhynchus keta of the Amur River basin by molecular datas A. G. Dragomeretskaya, Yu. I. Moskvina, V. O. Kotova, L. V. Butakova, S. I. Gaer, O. E. Trotsenko, E. V. Podorozhnyuk Russian Journal of Parasitology.2024; 18(4): 388. CrossRef
Four Human Cases of Diphyllobothrium nihonkaiense (Eucestoda: Diphyllobothriidae) in China with a Brief Review of Chinese Cases Yu-Chun Cai, Shao-Hong Chen, Hiroshi Yamasaki, Jia-Xu Chen, Yan Lu, Yong-Nian Zhang, Hao Li, Lin Ai, Hai-Ning Chen The Korean Journal of Parasitology.2017; 55(3): 319. CrossRef
Intestinal cestodes Camille Webb, Miguel M. Cabada Current Opinion in Infectious Diseases.2017; 30(5): 504. CrossRef
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