Parasites, Hosts and Diseases

"Feng Lu"

Brief Communication

Prevalence of asymptomatic malaria in high- and low-transmission areas of Tanzania: The role of asymptomatic carriers in malaria persistence and the need for targeted surveillance and control efforts: Ernest Mazigo, Hojong Jun, Wang-Jong Lee, Johnsy Mary Louis, Fadhila Fitriana, Jadidan Hada Syahada, Fauzi Muh, Feng Lu, Md Atique Ahmed, Seok Ho Cha, Wanjoo Chun, Won Sun Park, Se Jin Lee, Sunghun Na, Joon-Hee Han, Nyalali Kija, Smart Geodfrey, Eun-Teak Han, Jim Todd, Alphaxard Manjurano, Winifrida Kidima, Jin-Hee Han; Parasites Hosts Dis 2025;63(1):57-65.
Published online February 25, 2025; DOI: https://doi.org/10.3347/PHD.24077

As many countries implement different programs aimed at eliminating malaria, attention should be given to asymptomatic carriers that may interrupt the progress. This was a community-based cross-sectional study conducted in Tanzania from December 2022 to July 2023 within 4 villages from each of the 3 regions, Geita and Kigoma, which are high malaria transmission, and Arusha, which is low transmission. Malaria was diagnosed in asymptomatic individuals aged 1 year and older using the malaria rapid diagnostic test and light microscope. A total of 2,365 of 3,489 (67.9%) participants were enrolled from high-transmission villages. The overall prevalence was 25.5% and 15.8% by malaria rapid diagnostic test and light microscope, respectively. Using the respective tools, the prevalence was significantly higher at 35.6% (confidence interval (CI)=23.6–49.9) and 23.1% (CI=16.2–35.1) in the high-transmission regions (Geita and Kigoma) compared with 2.9% (CI=1.1–3.5) and 1.1% (CI=0.7–1.8) in the low-transmission region (Arusha). Children younger than 15 years and males accounted for the greatest proportion of infections. In the study area, the prevalence of asymptomatic cases was higher than that of reported symptomatic cases in health facilities. We hypothesize that these parasite reservoirs may contribute to the persistence of malaria in the country. Therefore, to achieve comprehensive malaria control in the country, the surveillance and screening of asymptomatic malaria cases are vital.

Citations

Citations to this article as recorded by

Hidden reservoirs of infection: prevalence and risk factors of asymptomatic malaria in a high-endemic region of Zambia
Wisdom Silwamba, David Chisompola, John Nzobokela, Martin Chakulya, Lombe Kabwe, Kingsley Tembo
Malaria Journal.2025;[Epub] CrossRef
Emergence of chloroquine-sensitive Plasmodium falciparum and rising resistance to first-line artemisinin partner drugs in Malawi
Ernest Mazigo, Hojong Jun, Wang-Jong Lee, Johnsy Mary Louis, Jadidan Hada Syahada, Fadhila Fitriana, Fauzi Muh, Md Atique Ahmed, Feng Lu, Joon-Hee Han, Tae-Hyung Kwon, Se Jin Lee, Sunghun Na, Wanjoo Chun, Won Sun Park, Eun-Taek Han, Winifrida Kidima, Jin-
Emerging Microbes & Infections.2025;[Epub] CrossRef
First report of pfhrp2 and pfhrp3 gene deletions compromising HRP2-based malaria rapid diagnostic tests in Malawi
Johnsy Mary Louis, Ernest Mazigo, Hojong Jun, Wang-Jong Lee, Jadidan Hada Syahada, Fadhila Fitriana, Fauzi Muh, Wanjoo Chun, Won Sun Park, Se Jin Lee, Sunghun Na, Feng Lu, Eun-Teak Han, Jin-Hee Han
Infectious Diseases of Poverty.2025;[Epub] CrossRef
Micro-geographic variation in antigenic diversity of PfEBA-175 region II in asymptomatic Plasmodium falciparum infections in Tanzania
Jadidan Hada Syahada, Wang-Jong Lee, Hojong Jun, Johnsy Mary Louis, Fadhila Fitriana, Fauzi Muh, Feng Lu, Md Atique Ahmed, Sunghun Na, Wanjoo Chun, Won Sun Park, Bo-Young Jeon, Eun-Teak Han, Jim Todd, Alphaxard Manjurano, Winifrida Kidima, Ernest Mazigo,
Frontiers in Immunology.2025;[Epub] CrossRef

3,628 View
127 Download
4 Web of Science
Crossref

Original Articles

Surveillance on the Vivax Malaria in Endemic Areas in the Republic of Korea Based on Molecular and Serological Analyses: Seong-Kyun Lee, Fengyue Hu, Egy Rahman Firdaus, Ji-Hoon Park, Jin-Hee Han, Sang-Eun Lee, Hyun-Il Shin, Shin Hyeong Cho, Won Sun Park, Feng Lu, Eun-Taek Han; Korean J Parasitol 2020;58(6):609-617.
Published online December 29, 2020; DOI: https://doi.org/10.3347/kjp.2020.58.6.609

Abstract
PDF

Plasmodium vivax reemerged in 1993. It has been sustained for more than 25 years and become one of the important indigenous parasitic diseases in northern and western parts of the Republic of Korea near the demilitarized zone. In particular, relapse is a significant concern for the control of malaria, as short- and long-term incubation periods vary among those infected in Korea. In this study, the prevalence of asymptomatic carriers was examined among residents of high endemic areas of vivax malaria during nonseasonal transmission of mosquitoes. Blood samples from 3 endemic regions in northwestern Korea were evaluated by microscopic examination, rapid diagnostic testing, and nested PCR to identify asymptomatic patients carrying malaria parasites in the community. However, no positive malaria case among residents of endemic areas was detected. Additionally, serological analysis was carried out to measure antibodies against 3 antigenic recombinant proteins of P. vivax, merozoite surface protein 1-19, circumsporozoite surface protein-VK210, and liver-stage antigen (PvLSA-N), by the protein array method. Interestingly, seropositivity of sera between previous exposure and samples without exposure to malaria was significantly higher using the PvLSA-N antigen than the other antigens, suggesting that PvLSA-N can be used as a serological marker to analyze the degree of exposure for malaria transmission in endemic areas. This indicates a very low asymptomatic carrier prevalence during the nonmalaria season in the endemic areas of Korea.

Citations

Citations to this article as recorded by

A region-structured model for early warning of Plasmodium vivax malaria transmission risk in the Republic of Korea
Boyeon Kim, Jung Ho Kim, Jeehyun Lee, Joon-Sup Yeom
Journal of Infection and Public Health.2025; 18(3): 102665. CrossRef
Development of a Plasmodium vivax malaria model for evaluating the effects of control strategies on the malaria burden in Democratic People’s Republic of Korea
Hye Seong, Jiyeon Suh, Jun Yong Choi, Jeehyun Lee, Joon-Sup Yeom
Frontiers in Public Health.2024;[Epub] CrossRef
Using Serological Markers for the Surveillance of Plasmodium vivax Malaria: A Scoping Review
Lejla Kartal, Ivo Mueller, Rhea J. Longley
Pathogens.2023; 12(6): 791. CrossRef
Recent Spatial and Temporal Trends of Malaria in Korea
Yeong Hoon Kim, Hye-Jin Ahn, Dongjae Kim, Sung-Jong Hong, Tong-Soo Kim, Ho-Woo Nam
The Korean Journal of Parasitology.2021; 59(6): 585. CrossRef

5,399 View
134 Download
4 Web of Science
Crossref

Characterization of Caveola-Vesicle Complexes (CVCs) Protein, PHIST/CVC-81₉₅ in Plasmodium vivax: Bo Wang, Feng Lu, Jin-Hee Han, Seong-Kyun Lee, Yang Cheng, Myat Htut Nyunt, Kwon-Soo Ha, Seok-Ho Hong, Won Sun Park, Eun-Taek Han; Korean J Parasitol 2016;54(6):725-732.
Published online December 31, 2016; DOI: https://doi.org/10.3347/kjp.2016.54.6.725

Abstract
PDF

Plasmodium vivax produces numerous caveola-vesicle complex (CVC) structures beneath the membrane of infected erythrocytes. Recently, a member helical interspersed subtelomeric (PHIST) superfamily protein, PcyPHIST/CVC-8195, was identified as CVCs-associated protein in Plasmodium cynomolgi and essential for survival of this parasite. Very little information has been documented to date about PHIST/CVC-81₉₅ protein in P. vivax. In this study, the recombinant PvPHIST/CVC-81₉₅ N and C termini were expressed, and immunoreactivity was assessed using confirmed vivax malaria patients sera by protein microarray. The subcellular localization of PvPHIST/CVC-81₉₅ N and C termini in blood stage parasites was also determined. The antigenicity of recombinant PvPHIST/CVC-81₉₅ N and C terminal proteins were analyzed by using serum samples from the Republic of Korea. The results showed that immunoreactivities to these proteins had 61% and 43% sensitivity and 96.9% and 93.8% specificity, respectively. The N terminal of PvPHIST/CVC-81₉₅ which contains transmembrane domain and export motif (PEXEL; RxLxE/Q/D) produced CVCs location throughout the erythrocytic-stage parasites. However, no fluorescence was detected with antibodies against C terminal fragment of PvPHIST/CVC-81₉₅. These results suggest that the PvPHIST/CVC-81₉₅ is localized on the CVCs and may be immunogenic in natural infection of P. vivax.

Citations

Citations to this article as recorded by

A novel micronemal protein MP38 is involved in the invasion of merozoites into erythrocytes
Tuyet-Kha Nguyen, Sy-Thau Nguyen, Van-Truong Nguyen, Sung-Hun Na, Robert W. Moon, Jetsumon Sattabongkot, Yee Ling Lau, Won-Sun Park, Wan-Joo Chun, Feng Lu, Seong-Kyun Lee, Jin-Hee Han, Eun-Taek Han, L. David Sibley, Niraj Harish Tolia
mBio.2025;[Epub] CrossRef
Caveola-vesicle complexes of Plasmodium vivax and Plasmodium cynomolgi: large-scale aggregation and structure of PHIST-positive vesicles in late schizont-infected red blood cells
Lawrence H. Bannister, Anton R. Dluzewski, Esmeralda V. S. Meyer, Stacey A. Lapp, Mary R. Galinski
Malaria Journal.2025;[Epub] CrossRef
Identification of a non-exported Plasmepsin V substrate that functions in the parasitophorous vacuole of malaria parasites
Aline Fréville, Margarida Ressurreição, Christiaan van Ooij, John C. Boothroyd
mBio.2024;[Epub] CrossRef
Novel secretory organelles of parasite origin ‐ at the center of host‐parasite interaction
Viktor Bekić, Nicole Kilian
BioEssays.2023;[Epub] CrossRef
Comparative spatial proteomics of Plasmodium-infected erythrocytes
Anthony Siau, Jing Wen Ang, Omar Sheriff, Regina Hoo, Han Ping Loh, Donald Tay, Ximei Huang, Xue Yan Yam, Soak Kuan Lai, Wei Meng, Irene Julca, Sze Siu Kwan, Marek Mutwil, Peter R. Preiser
Cell Reports.2023; 42(11): 113419. CrossRef
Molecular characterization of Plasmodium falciparum PHISTb proteins as potential targets of naturally-acquired immunity against malaria
Tony I. Isebe, Joel L. Bargul, Bonface M. Gichuki, James M. Njunge, James Tuju, Martin K. Rono
Wellcome Open Research.2021; 5: 136. CrossRef
Familial Hyperckemia and Calf Hypertrophy Secondary to a Caveolin-3 Mutation
Eduardo Otero-Loperena, Ana Ortiz-Santiago, Edwardo Ramos
American Journal of Physical Medicine & Rehabilitation.2021; 100(7): e101. CrossRef
Molecular characterization of Plasmodium falciparum PHISTb proteins as potential targets of naturally-acquired immunity against malaria
Tony I. Isebe, Joel L. Bargul, Bonface M. Gichuki, James M. Njunge, James Tuju, Martin K. Rono
Wellcome Open Research.2020; 5: 136. CrossRef

10,029 View
132 Download
6 Web of Science
Crossref

Brief Communication

Prevalence of Drug Resistance-Associated Gene Mutations in Plasmodium vivax in Central China: Feng Lu, Bo Wang, Jun Cao, Jetsumon Sattabongkot, Huayun Zhou, Guoding Zhu, Kwonkee Kim, Qi Gao, Eun-Taek Han; Korean J Parasitol 2012;50(4):379-384.
Published online November 26, 2012; DOI: https://doi.org/10.3347/kjp.2012.50.4.379

Abstract
PDF

Resistance of Plasmodium spp. to anti-malarial drugs is the primary obstacle in the fight against malaria, and molecular markers for the drug resistance have been applied as an adjunct in the surveillance of the resistance. In this study, we investigated the prevalence of mutations in pvmdr1, pvcrt-o, pvdhfr, and pvdhps genes in temperate-zone P. vivax parasites from central China. A total of 26 isolates were selected, including 8 which were previously shown to have a lower susceptibility to chloroquine in vitro. For pvmdr1, pvcrt-o, and pvdhps genes, no resistance-conferring mutations were discovered. However, a highly prevalent (69.2%), single-point mutation (S117N) was found in pvdhfr gene. In addition, tandem repeat polymorphisms existed in pvdhfr and pvdhps genes, which warranted further studies in relation to the parasite resistance to antifolate drugs. The study further suggests that P. vivax populations in central China may still be relatively susceptible to chloroquine and sulfadoxine-pyrimethamine.

Citations

Citations to this article as recorded by

Genetic Diversity of Potential Drug Resistance Markers in Plasmodium vivax Isolates from Panama, Mesoamerica
Vanessa Vásquez, Ana María Santamaría, Dianik Moreno, Fergie Ruíz, Chystrie A. Rigg, Luis F. Chaves, José E. Calzada
Pathogens.2025; 14(3): 231. CrossRef
Are pvcrt-o and pvmdr1 Gene Mutations Associated with Plasmodium vivax Chloroquine-Resistant Parasites?
Rebecca de Abreu-Fernandes, Natália Ketrin Almeida-de-Oliveira, Aline Rosa de Lavigne Mello, Lucas Tavares de Queiroz, Jacqueline de Aguiar Barros, Bárbara de Oliveira Baptista, Joseli Oliveira-Ferreira, Rodrigo Medeiros de Souza, Lilian Rose Pratt-Riccio
Biomedicines.2024; 12(1): 141. CrossRef
Polymorphisms of potential drug resistant molecular markers in Plasmodium vivax from China–Myanmar border during 2008‒2017
Zhensheng Wang, Chunyan Wei, Yunchun Pan, Zhihua Wang, Xin Ji, Qianqian Chen, Lianhui Zhang, Zenglei Wang, Heng Wang
Infectious Diseases of Poverty.2022;[Epub] CrossRef
Prevalence of pvmrp1 Polymorphisms and Its Contribution to Antimalarial Response
Yi Yin, Gangcheng Chen, Myat Htut Nyunt, Meihua Zhang, Yaobao Liu, Guoding Zhu, Xinlong He, Fang Tian, Jun Cao, Eun-taek Han, Feng Lu
Microorganisms.2022; 10(8): 1482. CrossRef
Assessing the in vitro sensitivity with associated drug resistance polymorphisms in Plasmodium vivax clinical isolates from Delhi, India
Monika Matlani, Amit Kumar, Vineeta Singh
Experimental Parasitology.2021; 220: 108047. CrossRef
Monitoring Plasmodium vivax resistance to antimalarials: Persisting challenges and future directions
Marcelo U. Ferreira, Tais Nobrega de Sousa, Gabriel W. Rangel, Igor C. Johansen, Rodrigo M. Corder, Simone Ladeia-Andrade, José Pedro Gil
International Journal for Parasitology: Drugs and Drug Resistance.2021; 15: 9. CrossRef
Phylogenetic analysis suggests single and multiple origins of dihydrofolate reductase mutations in Plasmodium vivax
Ayaz Shaukat, Qasim Ali, Lucy Raud, Abdul Wahab, Taj Ali Khan, Imran Rashid, Muhammad Rashid, Mubashir Hussain, Mushtaq A. Saleem, Neil D. Sargison, Umer Chaudhry
Acta Tropica.2021; 215: 105821. CrossRef
Antimalarial Drug Resistance and Implications for the WHO Global Technical Strategy
Matthew M. Ippolito, Kara A. Moser, Jean-Bertin Bukasa Kabuya, Clark Cunningham, Jonathan J. Juliano
Current Epidemiology Reports.2021; 8(2): 46. CrossRef
Polymorphism of Antifolate Drug Resistance in Plasmodium vivax From Local Residents and Migrant Workers Returned From the China-Myanmar Border
Weilin Zeng, Siqi Wang, Shi Feng, Daibin Zhong, Yue Hu, Yao Bai, Yonghua Ruan, Yu Si, Hui Zhao, Qi Yang, Xinxin Li, Xi Chen, Yanmei Zhang, Cuiying Li, Zheng Xiang, Yanrui Wu, Fang Chen, Pincan Su, Benjamin M. Rosenthal, Zhaoqing Yang
Frontiers in Cellular and Infection Microbiology.2021;[Epub] CrossRef
Molecular Surveillance and Ex Vivo Drug Susceptibilities of Plasmodium vivax Isolates From the China–Myanmar Border
Weilin Zeng, Hui Zhao, Wei Zhao, Qi Yang, Xinxin Li, Xiaosong Li, Mengxi Duan, Xun Wang, Cuiying Li, Zheng Xiang, Xi Chen, Liwang Cui, Zhaoqing Yang
Frontiers in Cellular and Infection Microbiology.2021;[Epub] CrossRef
Molecular Detection of Antimalarial Drug Resistance in Plasmodium vivax from Returned Travellers to NSW, Australia during 2008–2018
Chaturong Noisang, Wieland Meyer, Nongyao Sawangjaroen, John Ellis, Rogan Lee
Pathogens.2020; 9(2): 101. CrossRef
Plasmodium vivax drug resistance markers: Genetic polymorphisms and mutation patterns in isolates from Malaysia
Fei-Wen Cheong, Shairah Dzul, Mun-Yik Fong, Yee-Ling Lau, Sasheela Ponnampalavanar
Acta Tropica.2020; 206: 105454. CrossRef
Ex vivo susceptibilities of Plasmodium vivax isolates from the China-Myanmar border to antimalarial drugs and association with polymorphisms in Pvmdr1 and Pvcrt-o genes
Jiangyan Li, Jie Zhang, Qian Li, Yue Hu, Yonghua Ruan, Zhiyong Tao, Hui Xia, Jichen Qiao, Lingwen Meng, Weilin Zeng, Cuiying Li, Xi He, Luyi Zhao, Faiza A. Siddiqui, Jun Miao, Zhaoqing Yang, Qiang Fang, Liwang Cui, Kamala Thriemer
PLOS Neglected Tropical Diseases.2020; 14(6): e0008255. CrossRef
An unlabelled probe-based real time PCR and modified semi-nested PCR as molecular tools for analysis of chloroquine resistant Plasmodium vivax isolates from Afghanistan
Sayed Hussain Mosawi, Abdolhossein Dalimi, Najibullah Safi, Reza Fotouhi-Ardakani, Fatemeh Ghaffarifar, Javid Sadraei
Malaria Journal.2020;[Epub] CrossRef
Molecular surveillance for drug resistance markers in Plasmodium vivax isolates from symptomatic and asymptomatic infections at the China–Myanmar border
Yan Zhao, Lin Wang, Myat Thu Soe, Pyae Linn Aung, Haichao Wei, Ziling Liu, Tongyu Ma, Yuanyuan Huang, Lynette J. Menezes, Qinghui Wang, Myat Phone Kyaw, Myat Htut Nyunt, Liwang Cui, Yaming Cao
Malaria Journal.2020;[Epub] CrossRef
Selective sweep and phylogenetic models for the emergence and spread of pyrimethamine resistance mutations in Plasmodium vivax
Ayaz Shaukat, Qasim Ali, Timothy Connelley, Muhammad Azmat Ullah Khan, Mushtaq A. Saleem, Mike Evans, Imran Rashid, Neil D. Sargison, Umer Chaudhry
Infection, Genetics and Evolution.2019; 68: 221. CrossRef
Polymorphisms in genes associated with drug resistance of Plasmodium vivax in India
Vamsi Mohan Anantabotla, Hiasindh Ashmi Antony, Subhash Chandra Parija, Nonika Rajkumari, Jyoti R. Kini, Radhakrishna Manipura, Vijaya Lakshmi Nag, R. Gadepalli, Nirupama Chayani, Somi Patro
Parasitology International.2019; 70: 92. CrossRef
Molecular detection of drug resistant malaria in Southern Thailand
Chaturong Noisang, Christiane Prosser, Wieland Meyer, Waenurama Chemoh, John Ellis, Nongyao Sawangjaroen, Rogan Lee
Malaria Journal.2019;[Epub] CrossRef
Drug resistance genes: pvcrt-o and pvmdr-1 polymorphism in patients from malaria endemic South Western Coastal Region of India
Shiny Joy, Benudhar Mukhi, Susanta K. Ghosh, Rajeshwara N. Achur, D. Channe Gowda, Namita Surolia
Malaria Journal.2018;[Epub] CrossRef
Presence of novel triple mutations in the pvdhfr from Plasmodium vivax in Mangaluru city area in the southwestern coastal region of India
Shiny Joy, Susanta K. Ghosh, Rajeshwara N. Achur, D. Channe Gowda, Namita Surolia
Malaria Journal.2018;[Epub] CrossRef
The prevalence of molecular markers of drug resistance in Plasmodium vivax from the border regions of Thailand in 2008 and 2014
Kritpaphat Tantiamornkul, Tepanata Pumpaibool, Jittima Piriyapongsa, Richard Culleton, Usa Lek-Uthai
International Journal for Parasitology: Drugs and Drug Resistance.2018; 8(2): 229. CrossRef
Simultaneous detection of Plasmodium vivax dhfr, dhps, mdr1 and crt-o resistance-associated mutations in the Colombian Amazonian region
Juan Ricardo Cubides, Paola Andrea Camargo-Ayala, Carlos Hernando Niño, Diego Garzón-Ospina, Anggie Ortega-Ortegón, Estefany Ospina-Cantillo, María Fernanda Orduz-Durán, Manuel Elkin Patarroyo, Manuel Alfonso Patarroyo
Malaria Journal.2018;[Epub] CrossRef
Molecular Evidence of Drug Resistance in Asymptomatic Malaria Infections, Myanmar, 2015
Myat Htut Nyunt, Thinzar Shein, Ni Ni Zaw, Soe Soe Han, Fauzi Muh, Seong-Kyun Lee, Jin-Hee Han, Kyaw Zin Thant, Eun-Taek Han, Myat Phone Kyaw
Emerging Infectious Diseases.2017; 23(3): 517. CrossRef
Clinical and molecular surveillance of drug resistant vivax malaria in Myanmar (2009–2016)
Myat Htut Nyunt, Jin-Hee Han, Bo Wang, Khin Myo Aye, Kyin Hla Aye, Seong-Kyun Lee, Ye Htut, Myat Phone Kyaw, Kay Thwe Han, Eun-Taek Han
Malaria Journal.2017;[Epub] CrossRef
Low prevalence of dihydro folate reductase (dhfr) and dihydropteroate synthase (dhps) quadruple and quintuple mutant alleles associated with SP resistance in Plasmodium vivax isolates of West Bengal, India
Sabyasachi Das, Abhijit Banik, Amiya Kumar Hati, Somenath Roy
Malaria Journal.2016;[Epub] CrossRef
Polymorphisms in chloroquine resistance-associated genes in Plasmodium vivax in Ethiopia
Lemu Golassa, Berhanu Erko, Frederick N Baliraine, Abraham Aseffa, Göte Swedberg
Malaria Journal.2015;[Epub] CrossRef
Amplification of pfmdr1 , pfcrt , pvmdr1 , and K13 Propeller Polymorphisms Associated with Plasmodium falciparum and Plasmodium vivax Isolates from the China-Myanmar Bord
Jun Feng, Daili Zhou, Yingxue Lin, Huihui Xiao, He Yan, Zhigui Xia
Antimicrobial Agents and Chemotherapy.2015; 59(5): 2554. CrossRef
Molecular surveillance of pvdhfr, pvdhps, and pvmdr-1 mutations in Plasmodium vivax isolates from Yunnan and Anhui provinces of China
Bo Huang, Shiguang Huang, Xin-zhuan Su, Xinxin Tong, Junping Yan, Hongbin Li, Fangli Lu
Malaria Journal.2014;[Epub] CrossRef
Prevalence and patterns of antifolate and chloroquine drug resistance markers in Plasmodium vivax across Pakistan
Aamer A Khattak, Meera Venkatesan, Lubna Khatoon, Amed Ouattara, Leo J Kenefic, Muhammad F Nadeem, Farida Nighat, Salman A Malik, Christopher V Plowe
Malaria Journal.2013;[Epub] CrossRef
N-TerminalPlasmodium vivaxMerozoite Surface Protein-1, a Potential Subunit for Malaria Vivax Vaccine
Fernanda G. Versiani, Maria E. Almeida, Luis A. Mariuba, Patricia P. Orlandi, Paulo A. Nogueira
Clinical and Developmental Immunology.2013; 2013: 1. CrossRef
In vitro chloroquine resistance for Plasmodium vivax isolates from the Western Brazilian Amazon
Yonne F Chehuan, Monica RF Costa, Jacqueline S Costa, Maria GC Alecrim, Fátima Nogueira, Henrique Silveira, Larissa W Brasil, Gisely C Melo, Wuelton M Monteiro, Marcus VG Lacerda
Malaria Journal.2013;[Epub] CrossRef
High levels of IgG3 anti ICB2-5 in Plasmodium vivax-infected individuals who did not develop symptoms
Fernanda G Versiani, Maria EM Almeida, Gisely C Melo, Francivaldo OL Versiani, Patrícia P Orlandi, Luís André M Mariúba, Leidiane A Soares, Luciana P Souza, Antonio A da Silva Balieiro, Wuelton M Monteiro, Fabio TM Costa, Hernando A del Portillo, Marcus V
Malaria Journal.2013;[Epub] CrossRef
Prevalence of drug resistance associated mutations in Plasmodium vivax against sulphadoxine-pyrimethamine in southern Pakistan
Afsheen Raza, Najia K Ghanchi, Muhammad Shahzeb Khan, Mohammad Asim Beg
Malaria Journal.2013;[Epub] CrossRef
Blood Stage of Plasmodium vivax in Central China Is Still Susceptible to Chloroquine Plus Primaquine Combination Therapy
Eun-Taek Han, Yaobao Liu, Feng Lu, Qi Gao, Jun Cao, Guoding Zhu, Huayun Zhou
The American Journal of Tropical Medicine and Hygiene.2013; 89(1): 184. CrossRef