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"Hiroshi Yamasaki"

Case Report

Four Human Cases of Diphyllobothrium nihonkaiense (Eucestoda: Diphyllobothriidae) in China with a Brief Review of Chinese Cases
Yu-Chun Cai, Shao-Hong Chen, Hiroshi Yamasaki, Jia-Xu Chen, Yan Lu, Yong-Nian Zhang, Hao Li, Lin Ai, Hai-Ning Chen
Korean J Parasitol 2017;55(3):319-325.
Published online June 30, 2017
DOI: https://doi.org/10.3347/kjp.2017.55.3.319
We described 4 human infection cases of zoonotic fish-tapeworm, Diphyllobothrium nihonkaiense, identified with morphological and molecular characters and briefly reviewed Chinese cases in consideration of it as an emerging parasitic disease in China. The scolex and mature and gravid proglottids of some cases were seen, a rosette-shaped uterus was observed in the middle of the mature and gravid proglottids, and the diphyllobothriid eggs were yellowish-brown in color and displayed a small knob or abopercular protuberance on the opposite end of a lid-like opening. The average size of the eggs was recorded as 62-67×42-45 μm. The parasitic materials gathered from 4 human cases were morphologically identified as belonging to the genera Diphyllobothrium and Adenocephalus. The phylogenetic analysis based on the nucleotide sequences of cytochrome c oxidase subunit 1 gene of the etiologic agents confirmed that the 4 cases were D. nihonkaiense infection. The finding of 4 additional D. nihonkaiense cases suggests that D. nihonkaiense might be a major causative species of human diphyllobothriasis in China. A combined morphological and molecular analysis is the main method to confirm D. nihonkaiense infection.

Citations

Citations to this article as recorded by  Crossref logo
  • Dietary footprints of a global parasite: diagnosing Dibothriocephalus nihonkaiensis in non-endemic regions
    Wilson G.W. Goh, Jean-Marc Chavatte, Gabriel Z.R. Yan, Yuan Yi Constance Chen, Mark Dhinesh Muthiah, Lionel H.W. Lum
    Gut Pathogens.2025;[Epub]     CrossRef
  • Fish Pathogens and Associated Zoonotic Risks in Aquaculture: A Global One Health Perspective
    Fredrick Juma Syanya, Sajna Beegum, Zachariy Oreko Winam, Fazeena Fariq, A. R. Nikhila Khanna, Megha Lovejan, Mujeeb Rahiman K. M., Harikrishnan Mahadevan
    Aquaculture, Fish and Fisheries.2025;[Epub]     CrossRef
  • Molecular Identification of Dibothriocephalus nihonkaiense Infection Using Nanopore Sequencing: A Case Report and Literature Review
    Hin-Fung Tsang, Stanley W.M. Leung, Tin-Nok Hung, Icy Law, Ka-Wai Lam, Loiston Chan, Sze-Chuen Cesar Wong
    Diagnostics.2024; 14(24): 2871.     CrossRef
  • Human diphyllobothriosis in Taiwan: A review of cases and molecular evidence of Dibothriocephalus nihonkaiensis
    Chia-Kwung Fan, Daniel Barčák, Tomáš Scholz, Pasaikou Sonko, Martina Orosová, Kua-Eyre Su, Chun-Chao Chang, Yuarn-Jang Lee, Roman Kuchta, Mikuláš Oros
    Food and Waterborne Parasitology.2023; 33: e00213.     CrossRef
  • Global analysis of cytochrome c oxidase subunit 1 (cox1) gene variation in Dibothriocephalus nihonkaiensis (Cestoda: Diphyllobothriidae)
    Niichiro Abe, Takashi Baba, Yoshitaka Nakamura, Shintaro Murakami
    Current Research in Parasitology & Vector-Borne Diseases.2021; 1: 100042.     CrossRef
  • Dibothriocephalus nihonkaiensis: an emerging foodborne parasite in Brittany (France)?
    Brice Autier, Sorya Belaz, Brigitte Degeilh, Jean-Pierre Gangneux, Florence Robert-Gangneux
    Parasites & Vectors.2019;[Epub]     CrossRef
  • Epidemiology ofDiphyllobothrium nihonkaienseDiphyllobothriasis, Japan, 2001–2016
    Hiroshi Ikuno, Shinkichi Akao, Hiroshi Yamasaki
    Emerging Infectious Diseases.2018;[Epub]     CrossRef
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Brief Communication

A Recombinant Matrix Metalloproteinase Protein from Gnathostoma spinigerum for Serodiagnosis of Neurognathostomiasis
Penchom Janwan, Pewpan M. Intapan, Hiroshi Yamasaki, Porntip Laummaunwai, Kittisak Sawanyawisuth, Chaisiri Wongkham, Chatchai Tayapiwatana, Amnat Kitkhuandee, Viraphong Lulitanond, Yukifumi Nawa, Wanchai Maleewong
Korean J Parasitol 2013;51(6):751-754.
Published online December 31, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.6.751

Neurognathostomiasis is a severe form of human gnathostomiasis which can lead to disease and death. Diagnosis of neurognathostomiasis is made presumptively by using clinical manifestations. Immunoblotting, which recognizes antigenic components of molecular mass 21 kDa and 24 kDa in larval extracts of Gnathostoma spinigerum (Gs 21/24), has high sensitivity and specificity for diagnosis of neurognathostomiasis. However, only very small amounts of the Gs 21/24 antigens can be prepared from parasites harvested from natural or experimental animals. To overcome this problem, we recently produced a recombinant matrix metalloproteinase (rMMP) protein from G. spinigerum. In this study, we evaluated this rMMP alongside the Gs 21/24 antigens for serodiagnosis of human neurognathostomiasis. We studied sera from 40 patients from Srinagarind Hospital, Khon Kaen University, Thailand, with clinical criteria consistent with those of neurognathostomiasis, and sera from 30 healthy control adults from Thailand. All sera were tested for specific IgG antibodies against both G. spinigerum crude larval extract and rMMP protein using immunoblot analysis. The sensitivity and specificity for both antigenic preparations were all 100%. These results show that G. spinigerum rMMP protein can be used as an alternative diagnostic antigen, in place of larval extract, for serodiagnosis of neurognathostomiasis.

Citations

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  • Protein and antigen profiles of third-stage larvae of Gnathostoma spinigerum assessed with next-generation sequencing transcriptomic information
    Kathyleen Nogrado, Tipparat Thiangtrongjit, Poom Adisakwattana, Paron Dekumyoy, Sant Muangnoicharoen, Charin Thawornkuno, Onrapak Reamtong
    Scientific Reports.2022;[Epub]     CrossRef
  • Development of Immunochromatographic Test Kit for Rapid Detection of Specific IgG4 Antibody in Whole-Blood Samples for Diagnosis of Human Gnathostomiasis
    Penchom Janwan, Pewpan M. Intapan, Lakkhana Sadaow, Rutchanee Rodpai, Hiroshi Yamasaki, Patcharaporn Boonroumkaew, Oranuch Sanpool, Tongjit Thanchomnang, Phuangphaka Sadee, Wanchai Maleewong
    Diagnostics.2021; 11(5): 862.     CrossRef
  • Proteomics of Gnathostomiasis: A Way Forward for Diagnosis and Treatment Development
    Tipparat Thiangtrongjit, Kathyleen Nogrado, Thawatchai Ketboonlue, Preeyarat Malaitong, Poom Adisakwattana, Onrapak Reamtong
    Pathogens.2021; 10(9): 1080.     CrossRef
  • Combining lexical and context features for automatic ontology extension
    Sara Althubaiti, Şenay Kafkas, Marwa Abdelhakim, Robert Hoehndorf
    Journal of Biomedical Semantics.2020;[Epub]     CrossRef
  • Human gnathostomiasis: a neglected food-borne zoonosis
    Guo-Hua Liu, Miao-Miao Sun, Hany M. Elsheikha, Yi-Tian Fu, Hiromu Sugiyama, Katsuhiko Ando, Woon-Mok Sohn, Xing-Quan Zhu, Chaoqun Yao
    Parasites & Vectors.2020;[Epub]     CrossRef
  • Surveillance and diagnosis of zoonotic foodborne parasites
    Reza Zolfaghari Emameh, Sami Purmonen, Antti Sukura, Seppo Parkkila
    Food Science & Nutrition.2018; 6(1): 3.     CrossRef
  • 8,881 View
  • 101 Download
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Case Report

Sparganosis Presenting as Cauda Equina Syndrome with Molecular Identification of the Parasite in Tissue Sections
Adhiratha Boonyasiri, Pornsuk Cheunsuchon, Prajak Srirabheebhat, Hiroshi Yamasaki, Wanchai Maleewong, Pewpan M. Intapan
Korean J Parasitol 2013;51(6):739-742.
Published online December 31, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.6.739

A 52-year-old woman presented with lower back pain, progressive symmetrical paraparesis with sensory impairment, and sphincter disturbance. Magnetic resonance imaging (MRI) of the whole spine revealed multiple intradural extramedullary serpiginous-mass lesions in the subarachnoid space continuously from the prepontine to the anterior part of the medulla oblongata levels, C7, T2-T8, and T12 vertebral levels distally until the end of the theca sac and filling-in the right S1 neural foramen. Sparganosis was diagnosed by demonstration of the sparganum in histopathological sections of surgically resected tissues and also by the presence of serum IgG antibodies by ELISA. DNA was extracted from unstained tissue sections, and a partial fragment of mitochondrial cytochrome c oxidase subunit 1 (cox1) gene was amplified using a primer set specific for Spirometra spp. cox1. After sequencing of the PCR-amplicon and alignment of the nucleotide sequence data, the causative agent was identified as the larva of Spirometra erinaceieuropaei.

Citations

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  • Sparganosis of the Cauda Equina: A Rare Case of Lower Thoracic Cord Edema and Diagnostic Challenges
    Prasert Iampreechakul, Chonlada Angsusing, Sunisa Hangsapruek, Samasuk Thammachantha, Adisak Tanpun
    Asian Journal of Neurosurgery.2025; 20(02): 378.     CrossRef
  • A case of cerebral sparganosis diagnosed by surgical resection and molecular analysis
    Ryo Miyahara, Osamu Akiyama, Naoko Yoshida, Mai Suzuki, Karin Ashizawa, Takuma Kodama, Yuzaburo Shimizu, Akihide Kondo
    Surgical Neurology International.2025; 16: 512.     CrossRef
  • Description of Spirometra asiana sp. nov. (Cestoda: Diphyllobothriidae) found in wild boars and hound dogs in Japan
    Hiroshi Yamasaki, Hiromu Sugiyama, Yasuyuki Morishima, Hirotaka Kobayashi
    Parasitology International.2024; 98: 102798.     CrossRef
  • Establishment of Animal Infection Model of Spirometra Mansoni and Identification of Spirometra Mansoni by Enzyme-Linked Immunosorbent Assay
    Anqi Luo, Shuyu Chen, Mingye He, Xiaoruo Tan, Zhikang Li, Wei Liu, Yisong Liu
    Vector-Borne and Zoonotic Diseases.2024;[Epub]     CrossRef
  • Sparganosis parasitic tumor: Resectability and postoperative outcome, and analysis of cases from an endemic area in Indochina
    Amnuay Kleebayoon, Viroj Wiwanitkit
    Formosan Journal of Surgery.2023; 56(5): 160.     CrossRef
  • Multiple sparganosis spinal infections mainly in the thoracic region: A case report
    Gan-Jun Wen, Jian Chen, Shi-Fei Zhang, Zhi-Sen Zhou, Gen-Long Jiao
    World Journal of Clinical Cases.2023; 11(36): 8507.     CrossRef
  • Morphological Characteristics and Molecular Phylogenetic Evidence Support the Existence of a New Spirometra Species, Spirometra Asiana, (Cestoda: Diphyllobothriidae) in the Wild Boar
    Hiroshi Yamasaki, Hiromu Sugiyama, Yasuyuki Morishima
    SSRN Electronic Journal .2022;[Epub]     CrossRef
  • Spirometra species from Asia: Genetic diversity and taxonomic challenges
    Hiroshi Yamasaki, Oranuch Sanpool, Rutchanee Rodpai, Lakkhana Sadaow, Porntip Laummaunwai, Mesa Un, Tongjit Thanchomnang, Sakhone Laymanivong, Win Pa Pa Aung, Pewpan M. Intapan, Wanchai Maleewong
    Parasitology International.2021; 80: 102181.     CrossRef
  • Case Report: Sparganosis of the Cauda Equina
    Verajit Chotmongkol, Warinthorn Phuttharak, Kritsakorn Jingjit, Nipon Chaisuriya, Oranuch Sanpool, Soramon Chaichan, Sittichai Khamsai
    The American Journal of Tropical Medicine and Hygiene.2021; 104(1): 298.     CrossRef
  • Low prevalence of spargana infection in farmed frogs in the Yangtze River Delta of China
    Xiaoli Zhang, Rongsheng Mi, Yehua Zhang, Shijie Zhang, Tao Sun, Haiyan Jia, Yan Huang, Haiyan Gong, Xiangan Han, Zhaoguo Chen
    Infection, Genetics and Evolution.2020; 85: 104466.     CrossRef
  • Cauda equina syndrome secondary to extramedullary spinal sparganosis
    Tzu-Hsieh Hsu, Tzu-Tsao Chung, Yi-Ani Chen, Among-Hsuan Chung
    Formosan Journal of Surgery.2020; 53(6): 230.     CrossRef
  • Differential Diagnosis of Human Sparganosis Using Multiplex PCR
    Hyeong-Kyu Jeon, Kyu-Heon Kim, Woon-Mok Sohn, Keeseon S. Eom
    The Korean Journal of Parasitology.2018; 56(3): 295.     CrossRef
  • Rapid identification of nine species of diphyllobothriidean tapeworms by pyrosequencing
    Tongjit Thanchomnang, Chairat Tantrawatpan, Pewpan M. Intapan, Oranuch Sanpool, Viraphong Lulitanond, Somjintana Tourtip, Hiroshi Yamasaki, Wanchai Maleewong
    Scientific Reports.2016;[Epub]     CrossRef
  • Human sparganosis, a neglected food borne zoonosis
    Quan Liu, Ming-Wei Li, Ze-Dong Wang, Guang-Hui Zhao, Xing-Quan Zhu
    The Lancet Infectious Diseases.2015; 15(10): 1226.     CrossRef
  • Research Note. Cox-1 gene sequence of Spirometra in Pampas foxes from Argentina
    R. S. Petrigh, N. P. Scioscia, G. M. Denegri, M. H. Fugassa
    Helminthologia.2015; 52(4): 355.     CrossRef
  • Nine Human Sparganosis Cases in Thailand with Molecular Identification of Causative Parasite Species
    Wanchai Maleewong, Pewpan M. Intapan, Adhiratha Boonyasiri, Pornsuk Cheunsuchon, Hiroshi Yamasaki, Yupin Suputtamongkol, Oranuch Sanpool
    The American Journal of Tropical Medicine and Hygiene.2014; 91(2): 389.     CrossRef
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Articles from Symposium on Asian Taenia (October 2011, Osong, Korea)
Current Status and Perspectives of Cysticercosis and Taeniasis in Japan
Hiroshi Yamasaki
Korean J Parasitol 2013;51(1):19-29.
Published online February 18, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.1.19

This mini-review describes recent epidemiological trends in cysticercosis and taeniasis in Japan. Some of the topics discussed herein were presented at the first symposium on "Current perspectives of Taenia asiatica researches", that was held in Osong in Chungbuk Province, South Korea, in October 2011 and organized by Prof. K. S. Eom, Chungbuk National University School of Medicine. To better understand the trends in the occurrence of cysticercosis and taeniasis in Japan, clinical cases reported in 2005 have been updated. In addition, the current status of Taenia asiatica infections successively occurring in Japan since 2010 is also discussed.

Citations

Citations to this article as recorded by  Crossref logo
  • Taenia asiatica: Mitochondrial signatures based analysis of an emerging public health threat in India
    Aman D. Moudgil, Anil K. Nehra, Pallavi Moudgil
    New Microbes and New Infections.2025; 63: 101562.     CrossRef
  • Phylogenetic characterization of the pork tapeworm Taenia solium in Japan: implications for the enigmatic evolutionary history
    Naoki Hayashi, Ryo Kuwamoto, Mitsuhiro Okada, Kenta Suzuki, Takaya Hoketsu, Samuel Kelava, Yuma Ohari, Munehiro Okamoto, Kinpei Yagi, Nariaki Nonaka, Ryo Nakao
    International Journal for Parasitology.2025; 55(10): 497.     CrossRef
  • Successful Gastrografin Vermifugation for Taenia saginata-associated Appendicitis
    Keigo Kobayashi, Yasuhiro Umekawa
    Internal Medicine.2024; 63(23): 3185.     CrossRef
  • Development and evaluation of an immunochromatography-based point-of-care test kit for a rapid diagnosis of human cysticercosis
    Lakkhana Sadaow, Patcharaporn Boonroumkaew, Rutchanee Rodpai, Penchom Janwan, Oranuch Sanpool, Tongjit Thanchomnang, Yasuyuki Morishima, Marcello Otake Sato, Yasuhito Sako, Kaoru Kobayashi, Misako Iwai, Wanchai Maleewong, Hiroshi Yamasaki, Pewpan M. Intap
    Food and Waterborne Parasitology.2023; 33: e00211.     CrossRef
  • Current situation of human Taenia asiatica taeniosis in Japan
    Hiroshi Yamasaki, Yasuyuki Morishima, Hiromu Sugiyama, Munehiro Okamoto
    Parasitology International.2021; 83: 102340.     CrossRef
  • Epidemiology of Taenia saginata taeniosis/cysticercosis: a systematic review of the distribution in East, Southeast and South Asia
    Ramon M. Eichenberger, Lian F. Thomas, Sarah Gabriël, Branco Bobić, Brecht Devleesschauwer, Lucy J. Robertson, Anastasios Saratsis, Paul R. Torgerson, Uffe C. Braae, Veronique Dermauw, Pierre Dorny
    Parasites & Vectors.2020;[Epub]     CrossRef
  • Possible Reintroduction of Taenia asiatica in the Kanto Region of Japan
    Daisuke Taniyama, Izumi Inoue, Megumi Kawano, Chiaki Arakawa, Tomohide Adachi, Yasuyuki Morishima, Hiroshi Yamasaki, Hiromu Sugiyama
    Japanese Journal of Infectious Diseases.2019; 72(1): 62.     CrossRef
  • Taeniasis and cysticercosis in Asia: A review with emphasis on molecular approaches and local lifestyles
    Akira Ito, Tiaoying Li, Toni Wandra, Paron Dekumyoy, Tetsuya Yanagida, Munehiro Okamoto, Christine M Budke
    Acta Tropica.2019; 198: 105075.     CrossRef
  • Clinical characteristics and epidemiology of intestinal tapeworm infections over the last decade in Tokyo, Japan: A retrospective review
    Motoyuki Tsuboi, Kayoko Hayakawa, Hiroshi Yamasaki, Yuichi Katanami, Kei Yamamoto, Satoshi Kutsuna, Nozomi Takeshita, Shuzo Kanagawa, Norio Ohmagari, Yasuyuki Kato, Pablo Maravilla
    PLOS Neglected Tropical Diseases.2018; 12(2): e0006297.     CrossRef
  • A Case of Imported Taenia asiatica Infection in Japan
    Hiroki Namikawa, Yasuhiko Takemoto, Ikuji Shimazaki, Ayako Makuuchi, Masanori Kobayashi, Shigeki Kinuhata, Koichi Yamada, Hiroki Fujimoto, Hiromitsu Toyoda, Noriko Kamata, Yoshihiro Tochino, Isao Teramoto, Niichiro Abe, Mina Morimura, Hiroshi Kakeya, Taic
    Japanese Journal of Infectious Diseases.2018; 71(2): 170.     CrossRef
  • Epidemiology ofDiphyllobothrium nihonkaienseDiphyllobothriasis, Japan, 2001–2016
    Hiroshi Ikuno, Shinkichi Akao, Hiroshi Yamasaki
    Emerging Infectious Diseases.2018;[Epub]     CrossRef
  • Cysticercosis/taeniasis endemicity in Southeast Asia: Current status and control measures
    Hai-Wei Wu, Akira Ito, Lin Ai, Xiao-Nong Zhou, Luz P. Acosta, Arve Lee Willingham III
    Acta Tropica.2017; 165: 121.     CrossRef
  • Multiplex real-time PCR monitoring of intestinal helminths in humans reveals widespread polyparasitism in Northern Samar, the Philippines
    Catherine A. Gordon, Donald P. McManus, Luz P. Acosta, Remigio M. Olveda, Gail M. Williams, Allen G. Ross, Darren J. Gray, Geoffrey N. Gobert
    International Journal for Parasitology.2015; 45(7): 477.     CrossRef
  • Culinary delights and travel? A review of zoonotic cestodiases and metacestodiases
    Akira Ito, Christine M. Budke
    Travel Medicine and Infectious Disease.2014; 12(6): 582.     CrossRef
  • Epidemiology and genetic diversity of Taenia asiatica: a systematic review
    Anita Ale, Bjorn Victor, Nicolas Praet, Sarah Gabriël, Niko Speybroeck, Pierre Dorny, Brecht Devleesschauwer
    Parasites & Vectors.2014;[Epub]     CrossRef
  • Rapid Molecular Identification of Human Taeniid Cestodes by Pyrosequencing Approach
    Tongjit Thanchomnang, Chairat Tantrawatpan, Pewpan M. Intapan, Oranuch Sanpool, Penchom Janwan, Viraphong Lulitanond, Somjintana Tourtip, Hiroshi Yamasaki, Wanchai Maleewong, Emmanuel Dias-Neto
    PLoS ONE.2014; 9(6): e100611.     CrossRef
  • Priorities for research and control of cestode zoonoses in Asia
    Ning Xiao, Jia-Wen Yao, Wei Ding, Patrick Giraudoux, Philip S Craig, Akira Ito
    Infectious Diseases of Poverty.2013;[Epub]     CrossRef
  • Nothing is perfect! Trouble-shooting in immunological and molecular studies of cestode infections
    AKIRA ITO
    Parasitology.2013; 140(13): 1551.     CrossRef
  • 14,540 View
  • 131 Download
  • Crossref