Juha Song, C-Yoon Kim, Seo-Na Chang, Tamer Said Abdelkader, Juhee Han, Tae-Hyun Kim, Hanseul Oh, Ji Min Lee, Dong-Su Kim, Jong-Taek Kim, Hong-Shik Oh, Moonsuk Hur, Jae-Hwa Suh, Jae-Hak Park
Korean J Parasitol 2015;53(6):737-743. Published online December 31, 2015
In order to examine the prevalence of Cryptosporidium infection in wild rodents and insectivores of South Korea and to assess their potential role as a source of human cryptosporidiosis, a total of 199 wild rodents and insectivore specimens were collected from 10 regions of South Korea and screened for Cryptosporidium infection over a period of 2 years (2012-2013). A nested-PCR amplification of Cryptosporidium oocyst wall protein (COWP) gene fragment revealed an overall prevalence of 34.2% (68/199). The sequence analysis of 18S rRNA gene locus of Cryptosporidium was performed from the fecal and cecum samples that tested positive by COWP amplification PCR. As a result, we identified 4 species/genotypes; chipmunk genotype I, cervine genotype I, C. muris, and a new genotype which is closely related to the bear genotype. The new genotype isolated from 12 Apodemus agrarius and 2 Apodemus chejuensis was not previously identified as known species or genotype, and therefore, it is supposed to be a novel genotype. In addition, the host spectrum of Cryptosporidium was extended to A. agrarius and Crosidura lasiura, which had not been reported before. In this study, we found that the Korean wild rodents and insectivores were infected with various Cryptosporidium spp. with large intra-genotypic variationa, indicating that they may function as potential reservoirs transmitting zoonotic Cryptosporidium to livestock and humans.
Citations
Citations to this article as recorded by
Prevalence and novel genetic characteristics of Cryptosporidium spp. in wild rodents in the northern foothills of the Dabie Mountains, southeast Henan Province, China Mengyao Yang, Yin Fu, Pitambar Dhakal, Zi Yan, Jiashu Lang, Chaofeng Ma, Yuhong Jiang, Congzhou Wang, Longxian Zhang, Lihua Xiao, PLOS Neglected Tropical Diseases.2025; 19(5): e0013117. CrossRef
Critters and contamination: Zoonotic protozoans in urban rodents and water quality Siobhon Egan, Amanda D. Barbosa, Yaoyu Feng, Lihua Xiao, Una Ryan Water Research.2024; 251: 121165. CrossRef
Detection and Molecular Characterization of Giardia and Cryptosporidium spp. Circulating in Wild Small Mammals from Portugal Laura Lux, Rainer G. Ulrich, Sérgio Santos-Silva, João Queirós, Christian Imholt, Christian Klotz, Joana Paupério, Ricardo Pita, Hélia Vale-Gonçalves, Paulo Célio Alves, João R. Mesquita Animals.2023; 13(3): 515. CrossRef
Outbreak of severe diarrhea due to zoonotic Cryptosporidium parvum and C. xiaoi in goat kids in Chungcheongbuk-do, Korea Ah-Young Kim, Badriah Alkathiri, Subin Lee, Kyung-Duk Min, Soochong Kim, Sang-Myeong Lee, Wan-Kyu Lee, Dongmi Kwak, Seung-Hun Lee Parasitology Research.2023; 122(9): 2045. CrossRef
Cryptosporidium mortiferum n. sp. (Apicomplexa: Cryptosporidiidae), the species causing lethal cryptosporidiosis in Eurasian red squirrels (Sciurus vulgaris) Lenka Tůmová, Jana Ježková, Jitka Prediger, Nikola Holubová, Bohumil Sak, Roman Konečný, Dana Květoňová, Lenka Hlásková, Michael Rost, John McEvoy, Lihua Xiao, Monica Santín, Martin Kváč Parasites & Vectors.2023;[Epub] CrossRef
Public health and ecological significance of rodents in Cryptosporidium infections Kaihui Zhang, Yin Fu, Junqiang Li, Longxian Zhang One Health.2022; 14: 100364. CrossRef
Cryptosporidium rattin. sp. (Apicomplexa: Cryptosporidiidae) and genetic diversity ofCryptosporidiumspp. in brown rats (Rattus norvegicus) in the Czech Republic Jana Ježková, Jitka Prediger, Nikola Holubová, Bohumil Sak, Roman Konečný, Yaoyu Feng, Lihua Xiao, Michael Rost, John McEvoy, Martin Kváč Parasitology.2021; 148(1): 84. CrossRef
The Role of Peridomestic Rodents as Reservoirs for Zoonotic Foodborne Pathogens Nusrat A. Jahan, Laramie L. Lindsey, Peter A. Larsen Vector-Borne and Zoonotic Diseases.2021; 21(3): 133. CrossRef
Biodiversity of the Coccidia (Apicomplexa: Conoidasida) in vertebrates: what we know, what we do not know, and what needs to be done Donald W. Duszynski Folia Parasitologica.2021;[Epub] CrossRef
Genetic characterizations of Cryptosporidium spp. from pet rodents indicate high zoonotic potential of pathogens from chinchillas Jia Chen, Weijian Wang, Yu Lin, Lianbei Sun, Na Li, Yaqiong Guo, Martin Kvac, Una Ryan, Yaoyu Feng, Lihua Xiao One Health.2021; 13: 100269. CrossRef
Zoonotic Cryptosporidium spp. in Wild Rodents and Shrews Rauni Kivistö, Sofia Kämäräinen, Otso Huitu, Jukka Niemimaa, Heikki Henttonen Microorganisms.2021; 9(11): 2242. CrossRef
Taxonomy and molecular epidemiology of Cryptosporidium and Giardia – a 50 year perspective (1971–2021) Una M. Ryan, Yaoyu Feng, Ronald Fayer, Lihua Xiao International Journal for Parasitology.2021; 51(13-14): 1099. CrossRef
Molecular Detection of Cryptosporidium spp. and Enterocytozoon bieneusi Infection in Wild Rodents From Six Provinces in China Hong-Bo Ni, Yu-Zhe Sun, Si-Yuan Qin, Yan-Chun Wang, Quan Zhao, Zheng-Yao Sun, Miao Zhang, Ding Yang, Zhi-Hui Feng, Zheng-Hao Guan, Hong-Yu Qiu, Hao-Xian Wang, Nian-Yu Xue, He-Ting Sun Frontiers in Cellular and Infection Microbiology.2021;[Epub] CrossRef
Serosurvey and molecular detection of the main zoonotic parasites carried by commensal Rattus norvegicus population in Tehran, Iran Taher Azimi, Mohammad Reza Pourmand, Fatemeh Fallah, Abdollah Karimi, Roxana Mansour-Ghanaie, Seyedeh Mahsan Hoseini-Alfatemi, Mehdi Shirdoust, Leila Azimi Tropical Medicine and Health.2020;[Epub] CrossRef
Diversity of Cryptosporidium spp. in wild rodents from the Canary Islands, Spain Katherine García-Livia, Aarón Martín-Alonso, Pilar Foronda Parasites & Vectors.2020;[Epub] CrossRef
Diversity of Cryptosporidium spp. in Apodemus spp. in Europe Šárka Čondlová, Michaela Horčičková, Nikola Havrdová, Bohumil Sak, Lenka Hlásková, Agnieszka Perec-Matysiak, Marta Kicia, John McEvoy, Martin Kváč European Journal of Protistology.2019; 69: 1. CrossRef
Cryptosporidium apodemi sp. n. and Cryptosporidium ditrichi sp. n. (Apicomplexa: Cryptosporidiidae) in Apodemus spp. Šárka Čondlová, Michaela Horčičková, Bohumil Sak, Dana Květoňová, Lenka Hlásková, Roman Konečný, Michal Stanko, John McEvoy, Martin Kváč European Journal of Protistology.2018; 63: 1. CrossRef
Molecular characterizations of Cryptosporidium spp. and Enterocytozoon bieneusi in brown rats (Rattus norvegicus) from Heilongjiang Province, China Wei Zhao, Jianguang Wang, Guangxu Ren, Ziyin Yang, Fengkun Yang, Weizhe Zhang, Yingchu Xu, Aiqin Liu, Hong Ling Parasites & Vectors.2018;[Epub] CrossRef
Subtype analysis of zoonotic pathogen Cryptosporidium skunk genotype Wenchao Yan, Kerri Alderisio, Dawn M. Roellig, Kristin Elwin, Rachel M. Chalmers, Fengkun Yang, Yuanfei Wang, Yaoyu Feng, Lihua Xiao Infection, Genetics and Evolution.2017; 55: 20. CrossRef
Native and introduced squirrels in Italy host different Cryptosporidium spp. Jitka Prediger, Michaela Horčičková, Lada Hofmannová, Bohumil Sak, Nicola Ferrari, Maria Vittoria Mazzamuto, Claudia Romeo, Lucas A. Wauters, John McEvoy, Martin Kváč European Journal of Protistology.2017; 61: 64. CrossRef
Cryptosporidium homai n. sp. (Apicomplexa: Cryptosporidiiae) from the guinea pig (Cavia porcellus) Alireza Zahedi, Zoey Durmic, Alexander W. Gofton, Susan Kueh, Jill Austen, Malcolm Lawson, Lauren Callahan, John Jardine, Una Ryan Veterinary Parasitology.2017; 245: 92. CrossRef
A survey was performed to find out the intermediate hosts of Gnathostoma nipponicum in Jeju-do (Province), the Republic of Korea. In August 2009 and 2010, a total of 82 tadpoles, 23 black-spotted pond frogs (Rana nigromaculata), 7 tiger keelback snakes (Rhabdophis tigrinus tigrinus), 6 red-tongue viper snakes (Agkistrodon ussuriensis), and 2 cat snakes (Elaphe dione) were collected in Jeju-do and examined by the pepsin-HCl digestion method. Total 5 gnathostome larvae were detected in 3 (50%) of 6 A. ussuriensis, 70 larvae in 3 of 7 (42.9%) R. tigrinus tigrinus, and 2 larvae in 2 of 82 (8.7%) frogs. No gnathostome larvae were detected in tadpoles and cat snakes. The larvae detected were a single species, and 2.17×0.22 mm in average size. They had characteristic head bulbs, muscular esophagus, and 4 cervical sacs. Three rows of hooklets were arranged in the head bulbs, and the number of hooklets in each row was 29, 33, and 36 posteriorly. All these characters were consistent with the advanced third-stage larvae of G. nipponicum. It has been first confirmed in Jeju-do that R. nigromaculata, A. ussuriensis, and R. tigrinus tigrinus play a role for intermediate and/or paratenic hosts for G. nipponicum.
Citations
Citations to this article as recorded by
A Global Review of the Zoonotic Potential and Disease Risks of Amphibian Parasites in Bullfrog Aquaculture Meiqi Weng, Xinhua Liu, Chenxi Zhang, Rui Shu, Andrew Wang, Haotian Zhang, Xingqiang Wang, Huirong Yang, Jinyong Zhang Reviews in Aquaculture.2025;[Epub] CrossRef
Zoonotic Parasites in Reptiles, with Particular Emphasis on Potential Zoonoses in Australian Reptiles Tommy L. F. Leung Current Clinical Microbiology Reports.2024; 11(2): 88. CrossRef
A case of vocal cord gnathostomiasis diagnosed with sectional morphologies in a histopathological specimen from a Chinese woman living in Korea Doo Sik Park, Eun Hyun Cho, Kyung Hoon Park, Soo Min Jo, Bumjung Park, Sun Huh Parasites, Hosts and Diseases.2023; 61(3): 298. CrossRef
Three Nematode Species Recovered from Terrestrial Snakes in Republic of Korea Seongjun Choe, Junsik Lim, Hyun Kim, Youngjun Kim, Heejong Kim, Dongmin Lee, Hansol Park, Hyeong-Kyu Jeon, Keeseon S. Eom The Korean Journal of Parasitology.2016; 54(2): 205. CrossRef
Gnathostoma spinigerum Infection in the Upper Lip of a Korean Woman: An Autochthonous Case in Korea Jae Hee Kim, Hyemi Lim, Young-Sang Hwang, Tae Yeon Kim, Eun Mee Han, Eun-Hee Shin, Jong-Yil Chai The Korean Journal of Parasitology.2013; 51(3): 343. CrossRef
Adult gnathostomes were discovered in the stomach of the Jeju weasel, Mustela sibilica quelpartis, road-killed in Jeju-do (Province). Their morphological characters were examined to identify the species. Total 50 gnathostome adults were collected from 6 out of 10 weasels examined. In infected weasels, 4-6 worms were grouped and embedded in each granulomatous gastric tumor, except 1 weasel. Male worms were 25.0×1.4 mm in average size, and had a tail with pedunculate papillae, a spicule, and minute tegumental spines. Females were 40.0×2.5 mm in average size, and had a tail without tegumental spines. Pointed and posteriorly curved hooklets were arranged in 8-10 rows on the head bulb. Tegumental spines were distributed from behind the head bulb to the middle portion of the body. The spines were different in size and shape by the distribution level of the body surface. Fertilized eggs were 65.5×38.9 ?m in average size, and had a mucoid plug at 1 pole. These gnathostomes from Jeju weasels were identified as Gnathostoma nipponicum Yamaguti, 1941. By the present study, it was confirmed for the first time that G. nipponicum is distributed in Jeju-do, the Republic of Korea, and the Jeju weasel, M. sibilica quelpartis, plays a crucial role for its definitive host.
Citations
Citations to this article as recorded by
A case of vocal cord gnathostomiasis diagnosed with sectional morphologies in a histopathological specimen from a Chinese woman living in Korea Doo Sik Park, Eun Hyun Cho, Kyung Hoon Park, Soo Min Jo, Bumjung Park, Sun Huh Parasites, Hosts and Diseases.2023; 61(3): 298. CrossRef
Mustela sibirica (Carnivora: Mustelidae) Chris J Law Mammalian Species.2018; 50(966): 109. CrossRef
Gnathostoma spinigerum Infection in the Upper Lip of a Korean Woman: An Autochthonous Case in Korea Jae Hee Kim, Hyemi Lim, Young-Sang Hwang, Tae Yeon Kim, Eun Mee Han, Eun-Hee Shin, Jong-Yil Chai The Korean Journal of Parasitology.2013; 51(3): 343. CrossRef
Discovery of LarvalGnathostoma nipponicumin Frogs and Snakes from Jeju-do (Province), Republic of Korea Ho-Choon Woo, Hong-Shik Oh, Shin-Hyeong Cho, Byoung-Kuk Na, Woon-Mok Sohn The Korean Journal of Parasitology.2011; 49(4): 445. CrossRef
First
Prev
