Parasites, Hosts and Diseases

"Jae Ku Rhee"

Original Article

Age-dependent resistance to Cryptosporidium muris (strain MCR) infection in golden hamsters and mice: Jae Ku Rhee, Wang Su So, Hyeon Cheol Kim; Korean J Parasitol 1999;37(1):33-37.
Published online March 31, 1999; DOI: https://doi.org/10.3347/kjp.1999.37.1.33

Abstract
PDF

An age-dependent aspect of resistance to Cryptosporidium muris (strain MCR) infection was monitored in Syrian golden hamsters, Mesocricetus auratus, at 1-, 5- and 10-week of age and in ICR mice, Mus musculus, at 3-, 12-, and 15-week of age orally inoculated with a single dose of 2×10⁶ oocysts, respectively. The prepatent periods for both animals were similar, independent of age, but the patency was significantly longer in younger hamsters (P<0.001) and a long tendency in younger mice. Hamsters infected at 1-week of age excreted about 10 times higher oocysts than those at 5- and 10-week of age. However, the total oocyst output was similar among mice of different ages. There was a good correlation between the length of the patency and the total oocyst output in hamsters (R=0.9646), but not in mice (R=0.4561). The immunogenicity of the parasite to homologous challenge infections was very strong in hamsters and relatively strong in mice. These results indicate that acquired resistance to C. muris infection is age-related and the innate resistance is independent of age of hamsters, and that both innate and acquired resistance, on the contrary, are irrespective of age of mice.

Citations

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Totta Ehret, Francesca Torelli, Christian Klotz, Amy B. Pedersen, Frank Seeber
Frontiers in Cellular and Infection Microbiology.2017;[Epub] CrossRef
Cryptosporidium proliferans n. sp. (Apicomplexa: Cryptosporidiidae): Molecular and Biological Evidence of Cryptic Species within Gastric Cryptosporidium of Mammals
Martin Kváč, Nikola Havrdová, Lenka Hlásková, Tereza Daňková, Jiří Kanděra, Jana Ježková, Jiří Vítovec, Bohumil Sak, Ynes Ortega, Lihua Xiao, David Modrý, Jeba Rose Jennifer Jesudoss Chelladurai, Veronika Prantlová, John McEvoy, Herbert B. Tanowitz
PLOS ONE.2016; 11(1): e0147090. CrossRef
Cryptosporidium rubeyi n. sp. (Apicomplexa: Cryptosporidiidae) in multiple Spermophilus ground squirrel species
Xunde Li, Maria das Graças Cabral Pereira, Royce Larsen, Chengling Xiao, Ralph Phillips, Karl Striby, Brenda McCowan, Edward R. Atwill
International Journal for Parasitology: Parasites and Wildlife.2015; 4(3): 343. CrossRef
The Lesser Egyptian Gerbil (Gerbillus gerbillus) is a suitable host for the long-term propagation of Cryptosporidium andersoni
Martin Kváč, Zuzana Ondráčková, Dana Květoňová, John McEvoy, Jiří Vítovec, Michael Rost, Bohumil Sak
Experimental Parasitology.2013; 134(4): 438. CrossRef
Age-influenced population kinetics and immunological responses of Leishmania donovani in hamsters
Nasib Singh, Mukesh Samant, Shraddha K. Gupta, Awanish Kumar, Anuradha Dube
Parasitology Research.2007; 101(4): 919. CrossRef
Prevalence of cryptosporidian infection in cats in Turin and analysis of risk factors
Luisa Rambozzi, Arianna Menzano, Alessandro Mannelli, Simona Romano, Maria Cristina Isaia
Journal of Feline Medicine and Surgery.2007; 9(5): 392. CrossRef

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Brief Communication

Verification of immunosuppression in chicks caused by Cryptosporidium baileyi infection using Brucella abortus strain 1119-3: Jae Ku Rhee, Hong Ji Yang, Hyeon Cheol Kim; Korean J Parasitol 1998;36(4):281-284.
Published online December 20, 1998; DOI: https://doi.org/10.3347/kjp.1998.36.4.281

Abstract
PDF

Humoral immune response of young chicks to Brucella abortus strain 1119-3 inoculation was monitored to verify the degree of immunosuppression caused by infection with Cryptosporidium baileyi. Young chicks (2-day-old) were orally inoculated each with 2 × 10⁶ oocysts of C. baileyi, and then injected intramuscularly with 0.3 ml B. abortus strain 1119-3 containing 1 × 10⁹ living organisms on day 14 postinoculation (PI). Serum samples were tested by plate agglutination test on day 17 PI onwards at an interval of 3-6 days over a period of 36 days. Infected chicks with the coccidium showed significantly lower antibody titers than those of uninfected controls (P < 0.05). These findings document that C. baileyi infection in early life stage may predispose chicks easily to other potential poultry diseases.

Citations

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Outbreak of cryptosporidiosis in African penguins Spheniscus demersus
R Hurtado, NJ Parsons, TA Gous, Sv der Spuy, R Klusener, N Stander, E van Wilpe, RET Vanstreels
Diseases of Aquatic Organisms.2020; 140: 143. CrossRef
Cryptosporidium infections in birds - a review
Alex Akira Nakamura, Marcelo Vasconcelos Meireles
Revista Brasileira de Parasitologia Veterinária.2015; 24(3): 253. CrossRef
Effect of Cryptosporidium baileyi in specific pathogen free chickens vaccinated (CVI988/Rispens) and challenged with HPRS-16 strain of Marek's
H. Abbassi, F. Coudert, G. Dambrine, Y. Chérel, M. Naciri
Avian Pathology.2000; 29(6): 623. CrossRef
Cryptosporidiosis in birds — A review
T. Sréter, I. Varga
Veterinary Parasitology.2000; 87(4): 261. CrossRef

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Original Articles

Periodicity exhibited by Dirofilaria immitis microfilariae identified in dogs of Korea: Jae Ku Rhee, Sam Sung Yang, Hyeon Cheol Kim; Korean J Parasitol 1998;36(4):235-239.
Published online December 20, 1998; DOI: https://doi.org/10.3347/kjp.1998.36.4.235

Abstract
PDF

Microfilarial periodicity of Dirofilaria immitis (the dog heartworm) was determined at two hr intervals for 72 consecutive hrs in 10 naturally infected war dogs, 3-9 years old, in Korea to facilitate harvest of the microfilariae for possible use in laboratory works and to elucidate further the periodicity of the microfilaria depending on geographic location. Although the periodicity had been observed as being low-grade nocturnal, maximal microfilarial counts were found at 21:00 hr and minimal at 11:00 hr, giving rise to an evident peak in fluctuation of the larval counts. This is the first record of the periodicity of the microfilariae identified as D. immitis in Korea.

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Scientific Reports.2024;[Epub] CrossRef
The seroprevalence of canine dirofilariosis in dogs in the eastern coastal areas of China
Dongjie Cai, Bin Tian, Yongxia Liu, Mujeeb Ur Rehman, David Ranucci, Fabrizia Veronesi, Antonio Varcasia, Wanzhong Jia, Jianzhu Liu
Heliyon.2023; 9(6): e17009. CrossRef
Updates on the distribution and host spectrum of Dirofilaria repens in the Republic of Uzbekistan
Alisher Safarov, Firuza Akramova, Djalaliddin Azimov, Andrei D. Mihalca, Angela M. Ionică
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Acetic acid as an alternative reagent in the modified Knott test
Christopher C. Evans, Jenna L. Bradner, Molly D. Savadelis, C. Thomas Nelson, Andrew R. Moorhead
Veterinary Parasitology.2019; 276: 108975. CrossRef
Dirofilaria immitis and D. repens show circadian co-periodicity in naturally co-infected dogs
Angela Monica Ionică, Ioana Adriana Matei, Gianluca D’Amico, Lucia Victoria Bel, Mirabela Oana Dumitrache, David Modrý, Andrei Daniel Mihalca
Parasites & Vectors.2017;[Epub] CrossRef
Seasonality and circadian variation of microfilaremia in dogs experimentally infected with Dirofilaria immitis
Léonore Lovis, Mélanie Grandjean, Laurence Overney, Wolfgang Seewald, Heinz Sager
Veterinary Parasitology.2017; 243: 235. CrossRef
Dirofilaria immitis exhibits sex- and stage-specific differences in excretory/secretory miRNA and protein profiles
Lucienne Tritten, Damian Clarke, Scott Timmins, Tom McTier, Timothy G. Geary
Veterinary Parasitology.2016; 232: 1. CrossRef
Loa loa and Onchocerca ochengi miRNAs detected in host circulation
Lucienne Tritten, Maeghan O’Neill, Chuck Nutting, Samuel Wanji, Abdel Njouendoui, Fanny Fombad, Jonas Kengne-Ouaffo, Charles Mackenzie, Timothy Geary
Molecular and Biochemical Parasitology.2014; 198(1): 14. CrossRef
Detection of Circulating Parasite-Derived MicroRNAs in Filarial Infections
Lucienne Tritten, Erica Burkman, Andrew Moorhead, Mohammed Satti, James Geary, Charles Mackenzie, Timothy Geary, Thomas B. Nutman
PLoS Neglected Tropical Diseases.2014; 8(7): e2971. CrossRef
Seroprevalence and Geographic Distribution ofDirofilaria immitisand Tick-Borne Infections (Anaplasma phagocytophilum,Borrelia burgdorferisensu lato, andEhrlichia canis) in Dogs from Romania
Viorica Mircean, Mirabela Oana Dumitrache, Adriana Györke, Nikola Pantchev, Robert Jodies, Andrei Daniel Mihalca, Vasile Cozma
Vector-Borne and Zoonotic Diseases.2012; 12(7): 595. CrossRef
Prevalence of Dirofilaria immitis infection in dogs from Dandong, China
Honglie Hou, Guoshun Shen, Wei Wu, Pengtao Gong, Quan Liu, Juan You, Yanan Cai, Jianhua Li, Xichen Zhang
Veterinary Parasitology.2011; 183(1-2): 189. CrossRef
Prevalence and epidemiological aspects of Dirofilaria immitis in dogs from Kayseri Province, Turkey
A. Yildirim, A. Ica, O. Atalay, O. Duzlu, A. Inci
Research in Veterinary Science.2007; 82(3): 358. CrossRef
Genetic determinism of parasitic circadian periodicity and subperiodicity in human lymphatic filariasis
Gaston Pichon, Jean-Pierre Treuil
Comptes Rendus. Biologies.2004; 327(12): 1087. CrossRef
Seroprevalence of canine dirofilariosis in South Korea
K.H. Song, S.E. Lee, M. Hayasaki, K. Shiramizu, D.H. Kim, K.W. Cho
Veterinary Parasitology.2003; 114(3): 231. CrossRef

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Infection kinetics and developmental biology of Cryptosporidium muris (strain MCR) in Korean native kids and Corriedale lambs: Jae Ku Rhee, Hyeon Cheol Kim, Gil Soo Eun; Korean J Parasitol 1998;36(3):171-181.
Published online September 30, 1998; DOI: https://doi.org/10.3347/kjp.1998.36.3.171

Abstract
PDF

A total of nine Korean native kids and two Corriedale lambs, 1-20 days old, were each inoculated per os with a single dose of 2 × 10⁷ oocysts of Cryptosporidium muris (strain MCR) originated from mice to elucidate the kinetics and developmental stages of the coccidium in small ruminants. Irrespective of host's age, the prepatent period for both animals ranged from 19 to 35 days (28.1 days, on the average) and the patent period 16-85 days (47.8 days), and the total oocyst outputs showed enormous differences. Infection with greater numbers of oocyst outputs was not ordinarily established by transmission experiments. Oocysts discharged from the kids retained their infectivity by the mouse titration method. The immunogenicity of the coccidium and oocyst reproduction were proven by challenge infection and administration of prednisolone acetate, respectively. All the developmental stages of the coccidium in parasitophorous vacuoles were found by transmission electron microscopy in the pits of the gastric glands of a kid inoculated with oocysts and then necropsied on day 44 postinoculation. It indicated the full course of the host-parasite relationship in kids and lambs as well as mice.

Citations

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Cryptosporidium ubiquitum, C. muris and Cryptosporidium deer genotype in wild cervids and caprines in the Czech Republic
Michaela Kotkova, Karel Nemejc, Bohumil Sak, Vladimir Hanzal, Dana Kvetonova, Lenka Hlaskova, Sarka Condlova, John McEvoy, Martin Kvac
Folia Parasitologica.2016;[Epub] CrossRef
Cryptosporidium proliferans n. sp. (Apicomplexa: Cryptosporidiidae): Molecular and Biological Evidence of Cryptic Species within Gastric Cryptosporidium of Mammals
Martin Kváč, Nikola Havrdová, Lenka Hlásková, Tereza Daňková, Jiří Kanděra, Jana Ježková, Jiří Vítovec, Bohumil Sak, Ynes Ortega, Lihua Xiao, David Modrý, Jeba Rose Jennifer Jesudoss Chelladurai, Veronika Prantlová, John McEvoy, Herbert B. Tanowitz
PLOS ONE.2016; 11(1): e0147090. CrossRef
Variability in susceptibility of voles (Arvicolinae) to experimental infection with Cryptosporidium muris and Cryptosporidium andersoni
David Modrý, Lada Hofmannová, Zuzana Antalová, Bohumil Sak, Martin Kváč
Parasitology Research.2012; 111(1): 471. CrossRef
Cryptosporidium muris infection in bilbies (Macrotis lagotis)
KS WARREN, RA SWAN, UM MORGAN‐RYAN, JA FRIEND, A ELLIOT
Australian Veterinary Journal.2003; 81(12): 739. CrossRef
Prevalence of Cryptosporidium in sheep and goats bred on five farms in west-central region of Poland
Anna C Majewska, Anna Werner, Pawel Sulima, Tomasz Luty
Veterinary Parasitology.2000; 89(4): 269. CrossRef
Cryptosporidium andersoni n. sp. (Apicomplexa: Cryptosporiidae) from Cattle, Bos taurus
DAVID S. LINDSAY, STEVE J. UPTON, DOUGLAS S. OWENS, UNA M. MORGAN, JAN R. MEAD, BYRON L. BLAGBURN
Journal of Eukaryotic Microbiology.2000; 47(1): 91. CrossRef
Age-dependent resistance to Cryptosporidium muris (strain MCR) infection in golden hamsters and mice
Jae Ku Rhee, Wang Su So, Hyeon Cheol Kim
The Korean Journal of Parasitology.1999; 37(1): 33. CrossRef

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Brief Communication

Immunosuppressive effect of Cryptosporidium baileyi infection on vaccination against avian infectious bronchitis in chicks: Jae Ku Rhee, Hong Ji Yang, Sim Yong Yook, Hyeon Cheol Kim; Korean J Parasitol 1998;36(3):203-206.
Published online September 20, 1998; DOI: https://doi.org/10.3347/kjp.1998.36.3.203

Abstract
PDF

Two-day-old commercial chicks were inoculated orally with 2 × 10⁶ oocysts of Cryptosporidium baileyi and vaccinated with 10^3.5 EID₅₀/head of a commercially available avian infectious bronchitis (IB) live virus vaccine at 4 and 14 days following inoculation. Chicks infected with C. baileyi were shown to have an immunosuppressive effect on IB virus. It is concluded that infection with the protozoon in early life may increase their susceptibility to IB.

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Inactivation effects of slightly acidic electrolyzed water on Cryptosporidium baileyi and Eimeria tenella
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avian infectious bronchitis
Shahriar Behboudi
CABI Compendium.2022;[Epub] CrossRef
Serum metabolomics in chickens infected with Cryptosporidium baileyi
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Parasites & Vectors.2021;[Epub] CrossRef
Cryptosporidium infections in birds - a review
Alex Akira Nakamura, Marcelo Vasconcelos Meireles
Revista Brasileira de Parasitologia Veterinária.2015; 24(3): 253. CrossRef
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Abdelfattah H. Eladl, Hamed R. Hamed, Mostafa R. Khalil
Veterinary Research Communications.2014; 38(3): 237. CrossRef
Parasites of the digestive tract in free‐ranging birds in Greece
Margarita Papazahariadou, Anastasia Diakou, Elias Papadopoulos, Ioanna Georgopoulou, Anastasia Komnenou, Kostantina Antoniadou‐Sotiriadou
Journal of Natural History.2008; 42(5-8): 381. CrossRef
Reduced Serologic Response to Avian Influenza Vaccine in Specific-Pathogen-Free Chicks Inoculated with Cryptosporidium baileyi
Y-X. Hao, J-M. Yang, C. He, Q. Liu, Tim A. McAllister
Avian Diseases.2008; 52(4): 690. CrossRef
Effect of Cryptosporidium baileyi in specific pathogen free chickens vaccinated (CVI988/Rispens) and challenged with HPRS-16 strain of Marek's
H. Abbassi, F. Coudert, G. Dambrine, Y. Chérel, M. Naciri
Avian Pathology.2000; 29(6): 623. CrossRef
Cryptosporidiosis in birds — A review
T. Sréter, I. Varga
Veterinary Parasitology.2000; 87(4): 261. CrossRef
Verification of immunosuppression in chicks caused by Cryptosporidium baileyi infection using Brucella abortus strain 1119-3
J K Rhee, H J Yang, H C Kim
The Korean Journal of Parasitology.1998; 36(4): 281. CrossRef