We report here the records of 10 consecutive Korean patients (10 eyes) with ocular toxoplasmosis which showed the typical clinical manifestations with seropositivity for Toxoplasma gondii specific IgG antibodies by micro-ELISA between 2006 and 2010. Nine patients were males and 1 was female; their age was 50.5±13.8 years. The most common accompanying signs were vitritis (100%), anterior uveitis (70%), and scattered white deposit (80%). Pre-existing retinochoroidal scar was found in 1 (10%) patient. All patients received antiparasitic chemotherapy and systemic corticosteroid treatment, which resolved the presenting attack and recovered the visual acuity better than initial one in 9 patients and worse in 1. Optic atrophy, cataract, and retinal neovascularization were observed during the follow-up period and recurrence was detected in 3 eyes (30%) 6 to 20 months after the initial attack. In Korea, although rarely detected and reported, ocular toxoplasmosis needs more attention in clinical field of retinal diseases.
Citations
Citations to this article as recorded by
Identification of Coumarin-Chalcone and Coumarin-Pyrazoline Derivatives as Novel Anti-Toxoplasma gondii Agents Manal Ebaid, Maciej Chyb, Veronika Furlan, Hoda Ibrahim, Urban Bren, Justyna Gatkowska, Jarosław Dziadek, Wagdy Eldehna, Ahmed Sabt Drug Design, Development and Therapy.2024; Volume 18: 5599. CrossRef
Sulfadiazine analogs: anti-Toxoplasma in vitro study of sulfonamide triazoles Fadwa M Arafa, Doaa Hassan Osman, Mona Mohamed Tolba, Nadjet Rezki, Mohamed R Aouad, Mohamed Hagar, Mervat Osman, Heba Said Parasitology Research.2023; 122(10): 2353. CrossRef
Ocular Toxoplasmosis Eunice Jin Hui Goh, Ikhwanuliman Putera, Rina La Distia Nora, Padmamalini Mahendradas, Jyotirmay Biswas, Soon-Phaik Chee, Ilaria Testi, Carlos E Pavesio, Andre Luiz Land Curi, Daniel Vitor Vasconcelos-Santos, Atul Arora, Vishali Gupta, Alejandra de-la-Tor Ocular Immunology and Inflammation.2023; 31(7): 1342. CrossRef
Nanoformulation-Based 1,2,3-Triazole Sulfonamides for Anti-Toxoplasma In Vitro Study Fadwa M. Arafa, Heba Said, Doaa Osman, Nadjet Rezki, Mohamed R. Aouad, Mohamed Hagar, Mervat Osman, Bassma H. Elwakil, Mariusz Jaremko, Mona Mohamed Tolba Tropical Medicine and Infectious Disease.2023; 8(8): 401. CrossRef
Seroprevalence of Toxoplasma gondii assayed using Rapid Diagnostic Tests among Residents in Three Counties Adjacent to The Demilitarized Zone, Korea Jeehi Jung, Jinyoung Lee, Yoon Kyung Chang, Seong Kyu Ahn, Seo Hye Park, Sung-Jong Hong, Jihoo Lee, Chom-Kyu Chong, Hye-Jin Ahn, Ho-Woo Nam, Tong-Soo Kim, Dongjae Kim The Korean Journal of Parasitology.2021; 59(1): 9. CrossRef
Clusters of Toxoplasmosis in Ganghwa-gun, Cheorwon-gun, and Goseong-gun, Korea Jihye Yu, Woojin Kim, Yoon Kyung Chang, Tong-Soo Kim, Sung-Jong Hong, Hye-Jin Ahn, Ho-Woo Nam, Dongjae Kim The Korean Journal of Parasitology.2021; 59(3): 251. CrossRef
Recurrent Toxoplasma Retinitis Treated with Long-Term Oral Antibiotics Hosuck Yeom, Seung Hun Park, Heeyoon Cho, Yong Un Shin Journal of the Korean Ophthalmological Society.2021; 62(11): 1565. CrossRef
Review of Successful Control of Parasitic Infections in Korea Sung-Tae Hong, Tai-Soon Yong Infection & Chemotherapy.2020; 52(3): 427. CrossRef
Clusters of Toxoplasmosis in Gyodong-Myeon and Samsan-Myeon, Ganghwa-Gun, Korea Woojin Kim, Yoon Kyung Chang, Tong-Soo Kim, Sung-Jong Hong, Hye-Jin Ahn, Ho-Woo Nam, Dongjae Kim The Korean Journal of Parasitology.2020; 58(5): 493. CrossRef
Fulminant Toxoplasmic Chorioretinitis Following Intravitreal Dexamethasone Implantation Areum Jeong, Dong-Geun Park, Min Sagong Journal of the Korean Ophthalmological Society.2019; 60(9): 896. CrossRef
Patterns of ocular toxoplasmosis presenting at a tertiary eye care center in Korean patients Mirinae Kim, Seung Yong Choi, Jae Yon Won, Young-Hoon Park Medicine.2018; 97(15): e0399. CrossRef
Seroprevalence of Toxoplasmosis with ELISA and Rapid Diagnostic Test among Residents in Gyodong-do, Inchon city, Korea: A Four-Year Follow-up Yeong Hoon Kim, Ji hoo Lee, Seong kyu Ahn, Tong-Soo Kim, Sung-Jong Hong, Chom-Kyu Chong, Hye-Jin Ahn, Ho-Woo Nam The Korean Journal of Parasitology.2017; 55(3): 247. CrossRef
Seroprevalence of Toxoplasmosis Detected by RDT in Residents near the DMZ (demilitarized zone) of Cheorwon-gun, Gangwon-do, Korea Yeong Hoon Kim, Jihoo Lee, Young-Eun Kim, Seongkyu Ahn, Tong-Soo Kim, Sung-Jong Hong, Chom-Kyu Chong, Hye-Jin Ahn, Ho-Woo Nam The Korean Journal of Parasitology.2017; 55(4): 385. CrossRef
Seroprevalence of anti-Toxoplasma IgG and IgM among individuals who were referred to medical laboratories in Mazandaran province, northern Iran Mehdi Sharif, Ahmad Daryani, Zahra Ebrahimnejad, Shirzad Gholami, Ehsan Ahmadpour, Samaneh Borhani, Narges Lamsechi Journal of Infection and Public Health.2016; 9(1): 75. CrossRef
Spread and genotype of Toxoplasma gondii in naturally infected alpine chamois (Rupicapra r. rupicapra) Nicoletta Formenti, Alessandra Gaffuri, Tiziana Trogu, Roberto Viganò, Nicola Ferrari, Paolo Lanfranchi Parasitology Research.2016; 115(5): 2115. CrossRef
Ocular Inflammation Associated with Systemic Infection Byung Gil Moon, Joo Yong Lee Hanyang Medical Reviews.2016; 36(3): 192. CrossRef
Gefitinib Inhibits the Growth ofToxoplasma gondii in HeLa Cells Zhaoshou Yang, Hye-Jin Ahn, Ho-Woo Nam The Korean Journal of Parasitology.2014; 52(4): 439. CrossRef
High Expression of Water-Soluble Recombinant Antigenic Domains ofToxoplasma gondii Secretory Organelles Zhaoshou Yang, Hye-Jin Ahn, Ho-Woo Nam The Korean Journal of Parasitology.2014; 52(4): 367. CrossRef
Clinical Features and Treatment of Ocular Toxoplasmosis Young-Hoon Park, Ho-Woo Nam The Korean Journal of Parasitology.2013; 51(4): 393. CrossRef
A Surge in the Seroprevalence of Toxoplasmosis among the Residents of Islands in Gangwha-gun, Incheon, Korea Zhaoshou Yang, Pyo Yun Cho, Seong Kyu Ahn, Hye-Jin Ahn, Tong-Soo Kim, Chom-Kyu Chong, Sung-Jong Hong, Seok Ho Cha, Ho-Woo Nam The Korean Journal of Parasitology.2012; 50(3): 191. CrossRef
Seroprevalence of Toxoplasmosis in the Residents of Cheorwon-gun, Gangwon-do, Korea Hye-Jin Ahn, Pyo Yun Cho, Seong Kyu Ahn, Tong-Soo Kim, Chom-Kyu Chong, Sung-Jong Hong, Seok Ho Cha, Ho-Woo Nam The Korean Journal of Parasitology.2012; 50(3): 225. CrossRef
Detection of Ocular Toxoplasma gondii Infection in Chronic Irregular Recurrent Uveitis by PCR Sang-Eun Lee, Sung-Hee Hong, Seong-Ho Lee, Young-Il Jeong, Su Jin Lim, Oh Woong Kwon, Sun Hyun Kim, Young Sung You, Shin-Hyeong Cho, Won-Ja Lee The Korean Journal of Parasitology.2012; 50(3): 229. CrossRef
Maintained Seroprevalence of Toxoplasmosis among the Residents of Jeju Island, Korea Sung-Jong Hong, Chom-Kyu Chong, Kyutaeg Lee, Tong-Soo Kim, Yeon-Pyo Hong, Hye-Jin Ahn, Hak-Yong Kim, A-Ra Ko, Yong-Joo Kim, Ho-Woo Nam The Korean Journal of Parasitology.2011; 49(3): 309. CrossRef
First
Prev
