The cestode Taenia hydatigena uses canids, primarily dogs, as definitive hosts, while the metacestode larval stage cysticercus infects a range of intermediate hosts, including domestic animals such as goats, sheep, and pigs. Cysticercosis due to T. hydatigena has large veterinary and economic drawbacks. Like other taeniids, e.g., Echinococcus, intraspecific variation is found among the members of the genus Taenia. In Africa, few studies are available on the epidemiology and distribution of T. hydatigena, and even fewer studies are available on its genetic variation. In this study, we molecularly identified 11 cysticerci from sheep in Sudan and demonstrated the genetic variation based on the NADH dehydrogenase subunit 1 (nad1) and cytochrome c oxidase subunit 1 (cox1) mitochondrial genes. The isolates were correctly identified as T. hydatigena with more than 99% similarity to those in the GenBank database. Low diversity indices and insignificant neutrality indices were observed, with 3 and 2 haplotypes for the nad1 and cox1 genes, respectively. The results suggest the presence of unique T. hydatigena haplotypes in Sudan, as haplotypes with 100% similarity were not found in the GenBank database. With few available studies on the genetic variation of T. hydatigena in Africa, this report represents the first insights into the genetic variation of T. hydatigena in Sudan and constitutes useful data.
Citations
Citations to this article as recorded by
Identification of protein extracts from cysticercus tenuicollis using SDS–PAGE method collected from sheep in slaughterhouse, Kerbala Provenance, Iraq Jihad Talib Obead, Bariq Abd Alameer Mohammed, Hayder Talib Mahdi, Ihsan Mohammed Sulbi Eximia.2025; 14(1): 211. CrossRef
PREVALENCE AND ASSOCIATED RISK FACTORS OF Cysticercus tenuicollis IN THE SMALL RUMINANTS IN DIFFERENT DISTRICTS OF PUNJAB AND KPK PROVINCES OF PAKISTAN W Qamar, R.Z. Abbas, M Imran, M.S. Mahmood The Journal of Animal and Plant Sciences.2025; (4): 935. CrossRef
Molecular Identification of Cryptic Cysticercosis: Taenia spp. in Wild and Domestic Intermediate Hosts in Kazakhstan Vladimir Kiyan, Ainura Smagulova, Rabiga Uakhit, Carlos Hermosilla, Lyudmila Lider, Karina Jazina, Nurassyl Manapov Diversity.2025; 17(9): 655. CrossRef
Acute visceral cysticercosis in a Black Bengal goat: A case report of hepatitis cysticercosa and pneumonitis cysticercosa Vinay Kumar S.D., Sree Lakshmi P., Neha, Avantika Srivastav, Manohar S., Veena R. Sutar, Pawan Kumar, Rajveer Singh Pawaiya, Vidya Singh Veterinary Parasitology: Regional Studies and Reports.2025; 66: 101378. CrossRef
Genetic diversity and haplotypes of Cysticercus tenuicollis isolates from slaughtered sheep and goats in Elazig and Bingol provinces of Turkey Sirvan Karakoc, Harun Kaya Kesik, Figen Celik, Muhammed Ahmed Selcuk, Seyma Gunyakti Kilinc, Sami Simsek Veterinary Medicine and Science.2024;[Epub] CrossRef
Leading report regarding the molecular epidemiology of Taenia hydatigena from Pakistan and global overview of the genetic diversity and population structure of the parasite Naunain Mehmood, Hira Muqaddas, Aqsa Ashraf, Mahnoor Aslam, Maryam Khan, Madiha Fatima, Rahman Qadir, Samir Ibenmoussa, Turki M. Dawoud, Muhammad Irfan Ullah, Furhan Iqbal Comparative Immunology, Microbiology and Infectious Diseases.2024; 114: 102248. CrossRef
Molecular Identification of Selected Cervid Helminths in Supplementarily Fed European Bison Population Magdalena Świsłocka-Cutter, Rafał Kowalczyk, Anetta Borkowska, Tomasz Kamiński, Marta Kołodziej-Sobocińska, María Eugenia López-Arellano Journal of Parasitology Research.2024;[Epub] CrossRef
Epidemiology of Cysticercus tenuicollis in Sheep and Goats in the Tropics: A Systematic Review Prudentia Yensi Lawan, Aziwo Tatanja Niba, Julius Awah-Ndukum, Francesca Mancianti Veterinary Medicine International.2024;[Epub] CrossRef
PCR‐RFLP assay confirms the existence of different mitochondrial lineages of Taenia hydatigena including a possible geographically restricted group John Asekhaen Ohiolei, Hong‐Bin Yan, Li Li, Mughees Aizaz Alvi, Rosline James Muku, Yao‐Dong Wu, Nian‐Zhang Zhang, Wen‐Hui Li, Ai‐Min Guo, Xue‐Lin Wang, Bao‐Quan Fu, Wan‐Zhong Jia Transboundary and Emerging Diseases.2022; 69(4): 2390. CrossRef
Prevalence and genetic variance of Taenia hydatigena in goats and sheep from northern Ghana: Preliminary data on a globally neglected livestock parasite Francis Addy, Gideon Adu-Bonsu, Angelina Evelyn Dickson, Derrick Dankwa, Randy Aryee, Osman A. Dufailu, Thomas Romig, Marion Wassermann Veterinary Parasitology: Regional Studies and Reports.2022; 30: 100711. CrossRef
Molecular identification of Taenia hydatigena from domestic and free-living animals in Slovakia, Central Europe Júlia Jarošová, Daniela Antolová, Adriana Iglodyová, Alžbeta Königová, Michaela Urda Dolinská, Bronislava Víchová Parasitology Research.2022; 121(5): 1345. CrossRef
Comparison of mitochondrial genetic variation of Taenia hydatigena cysticerci from China and Mongolia Sayed Ajmal Qurishi, Hong-Bin Yan, Li Li, John Aeskhaen Ohiolei, Mughees Aizaz Alvi, Lin-Sheng Zhang, Ha Da, Hong-Mei Qiao, Nigus Abebe Shumuye, Bao Hua, Bing-Xin Bai, Wen-Jun Tian, Ju-Mei Xu, Bao-Quan Fu, Wan-Zhong Jia Parasitology Research.2022; 121(12): 3455. CrossRef
A new molecular nomenclature for Taenia hydatigena: mitochondrial DNA sequences reveal sufficient diversity suggesting the assignment of major haplotype divisions John Asekhaen Ohiolei, Hong-Bin Yan, Li Li, Wen-Hui Li, Yao-Dong Wu, Mughees Aizaz Alvi, Nian-Zhang Zhang, Bao-Quan Fu, Xue-Lin Wang, Wan-Zhong Jia Parasitology.2021; 148(3): 311. CrossRef
Molecular Characterization and Phylogeny of Taenia hydatigena and Echinococcus granulosus from Iranian Sheep and Cattle Based on COX1 Gene Vahid Raissi, Soudabeh Etemadi, Nasrin Sohrabi, Omid Raiesi, Mehdi Shahraki, Alireza Salimi-Khorashad, Asmaa Ibrahim Current Microbiology.2021; 78(4): 1202. CrossRef
Molecular characterization ofCysticercus tenuicollisisolates from sheep in the Nile Delta, Egypt and a review onTaenia hydatigenainfections worldwide Ibrahim Abbas, El-Sayed El-Alfy, Elisabeth Janecek-Erfurth, Christina Strube Parasitology.2021; 148(8): 913. CrossRef
Prevalence and risk factors of Taenia hydatigena in dogs, pigs, and cattle in the Central Highlands of Vietnam Dinh Ng-Nguyen, Thai Van Nguyen, Trong Van Nguyen, Hieu Quoc Nguyen, Van-Anh Thi Nguyen Parasitology Research.2021; 120(9): 3245. CrossRef
Preliminary information on the prevalence and molecular description of Taenia hydatigena isolates in Pakistan based on mitochondrial cox1 gene Mughees Aizaz Alvi, John Asekhaen Ohiolei, Muhammad Saqib, Li Li, Nehaz Muhammad, Muhammad Haleem Tayyab, Warda Qamar, Anum Aizaz Alvi, Yao-Dong Wu, Xiu-Rong Li, Bao-Quan Fu, Hong-Bin Yan, Wan-Zhong Jia Infection, Genetics and Evolution.2020; 85: 104481. CrossRef
Some small mammals occur as household pests and harbour a number of parasites that could be of public health importance. This study profiled the helminth and protozoan parasites in trapped small mammals within and around human dwelling places (houses) located across 4 major towns (Auchi, Benin, Ekpoma, and Uromi) and environs in Edo state, Nigeria. Six genera (Apodemus sp., Crocidura sp., Mastomys natalensis, Mus musculus, Rattus sp., and Sorex sp.) were identified from 502 trapped small mammals. Overall, M. musculus (71.9%) and Rattus rattus (20.1%) were the most frequently trapped. In total, on examination of blood, gastrointestinal contents, and brain tissues, 12 helminth taxa (Angiostrongylus sp., Aspicularis sp., Capillaria sp., Gongylonema sp., Heterakis spumosa, Hymenolepis diminuta, Hymenolepis nana, Mastophorus muris, Moniliformis moniliformis, Nippostrongylus brasiliensis, Strongyloides sp., Trichosomoides sp., and Trichuris sp.), and 6 protozoan parasites (Babesia sp., Trypanosoma lewisi, Plasmodium sp., Eimeria sp., Isospora sp., and Toxoplasma gondii) were isolated. Most prevalent helminths with relatively heavy mean intensity were Strongyloides sp. and Heterakis spumosa, while Plasmodium, Eimeria, and Isospora were the most prevalent protozoan parasites. Generally, intrinsic factors like sex and age had marginal influence on the rate and burden of infection in M. musculus and R. rattus. Although the infection rate and prevalence of zoonotic parasites were low, they were largely recovered in rodents from Ekpoma. This study elucidates the public health implication of the presence of zoonotic parasites in these small mammals.
Citations
Citations to this article as recorded by
Phylogenetic and genetic evolutionary analyses of the mitochondrial genome of
Mastophorus muris
in
Neodon fuscus
from the Qinghai-Tibetan Plateau
Hongrun Ge, Haining Zhang, Ru Meng, Shengrui Xu, Hailong Zhao, Weishan Lin, Jing Li, Yong Fu, Jian Li Microbiology Spectrum.2025;[Epub] CrossRef
Zoonotic importance of ecto- and endoparasites in rodents in Malaysia: a review Firdaus Mohd-Qawiem, Md Isa Nur-Mahiza, Nur Indah Ahmad, Abd Rahaman Yasmin, Saulol Hamid Nur-Fazila Journal of Veterinary Science.2024;[Epub] CrossRef
Occurrence of multiple infections of rodents with parasites and bacteria in the Sibang Arboretum, Libreville, Gabon Patrice Makouloutou-Nzassi, Chimène Nze-Nkogue, Boris Kevin Makanga, Neil Michel Longo-Pendy, Judi Armel Bourobou Bourobou, Branly Cordia Bikie Bi Nso, Etienne François Akomo-Okoue, Cherone-Cheba Mbazoghe-Engo, Félicien Bangueboussa, Silas Lendzele Sevidz Veterinary World.2024; : 2506. CrossRef
The Parasites that can be Found in the Mus musculus House Mice Dilara KARAMAN, Ahmet Onur GİRİŞGİN Commagene Journal of Biology.2022;[Epub] CrossRef
Detection of rodent-borne parasitic pathogens of wild rats in Serdang, Selangor, Malaysia: A potential threat to human health Mustapha Tijjani, Roslaini Abd Majid, Sharif Alhassan Abdullahi, Ngah Zasmy Unyah International Journal for Parasitology: Parasites and Wildlife.2020; 11: 174. CrossRef
A Review of Strongyloides spp. Environmental Sources Worldwide Mae A. F. White, Harriet Whiley, Kirstin E. Ross Pathogens.2019; 8(3): 91. CrossRef
First
Prev
