Parasites, Hosts and Diseases

"Jung-Won Park"

Brief Communication

Detection of trichomonads in induced sputum from asthma patients in Korea: Myung-hee Yi, Myungjun Kim, Jun Ho Choi, Yoon Hee Cho, Hyun Kyung Oh, Jung-Won Park, Ju Yeong Kim; Parasites Hosts Dis 2025;63(3):254-257.
Published online August 20, 2025; DOI: https://doi.org/10.3347/PHD.25028

Abstract
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Trichomonads are flagellated protozoa that have occasionally been detected in the human respiratory tract, although detection rates have often been underestimated. We applied a nested PCR assay targeting the 18S rRNA gene of trichomonads to induced sputum from asthma patients to determine the prevalence of Trichomonas. Induced sputum was collected from 41 adults with asthma and analyzed through nested PCR using broad-range trichomonad primers and DNA sequencing for species identification. Nested PCR detected trichomonad DNA in 10 of the 41 (24.4%) samples. Sequencing and phylogenetic analysis revealed Trichomonas tenax in 8 cases and Tetratrichomonas sp. in 2 cases. These findings indicate that trichomonads can be present in the lower airways of patients with asthma, warranting further investigation into their clinical relevance.

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Case Report

Human Sting of Cephalonomia gallicola (Hymenoptera: Bethylidae) in Korea: In-Yong Lee, Chang-Seob Shin, Seobo Sim, Jung-Won Park, Tai-Soon Yong; Korean J Parasitol 2014;52(6):681-684.
Published online December 23, 2014; DOI: https://doi.org/10.3347/kjp.2014.52.6.681

Abstract
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Hymenoptera stings can cause serious injury to humans. We report the clinical findings of 6 cases of Hymenoptera stings. All patients developed painful erythematous papules at the sting sites and had a past history of parasitoid wasp sting. This is the first clinical report of the parasitoid wasp, Cephalonomia gallicola, causing human stings in Korea.

Citations

Citations to this article as recorded by

Human ectoparasitoses caused by flat wasps of the genera Sclerodermus and Cephalonomia (Hymenoptera: Bethylidae)
Paolo Masini, Luca Stingeni, Gianandrea Salerno, Valerio Saitta, Celso O Azevedo, Manuela Rebora, Matteo Ornielli, Katharina Hansel, Leonardo Bianchi, Gabriele Casciola
Clinical and Experimental Dermatology.2025; 50(8): 1508. CrossRef
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A Review of Sclerodermus Latreille, 1809 (Hymenoptera: Bethylidae) Infestations and Report of the First Case in North America North of Mexico
Michael J Skvarla
Journal of Medical Entomology.2018; 55(3): 752. CrossRef
Bethylids attacking stored‐product pests: an overview
Marco Amante, Matthias Schöller, Pompeo Suma, Agatino Russo
Entomologia Experimentalis et Applicata.2017; 163(3): 251. CrossRef
Dermatitis caused by arthropods in domestic environment: an Italian multicentre study
L. Stingeni, L. Bianchi, K. Hansel, D. Neve, C. Foti, M. Corazza, V. Bini, I. Moretta, M. Principato
Journal of the European Academy of Dermatology and Venereology.2017; 31(9): 1526. CrossRef

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Original Articles

Identification of Chironomus kiiensis allergens, a dominant species of non-biting midges in Korea: Tai-Soon Yong, Jong-Seok Lee, In-Yong Lee, Soon-Jung Park, Gab-Man Park, Han-Il Ree, Jung-Won Park, Chein-Soo Hong, Hae-Sim Park; Korean J Parasitol 1999;37(3):171-179.
Published online September 30, 1999; DOI: https://doi.org/10.3347/kjp.1999.37.3.171

Abstract
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Non-biting midges are known to contain potent inhalant allergens. IgE antibody responses to the crude extract of Chironomus kiiensis adults, a dominant chironomid species in Korea, were examined. With the IgE-ELISA or passive cutaneous anaphylaxis reactions, increased levels of chironomid-specific IgE were detected in the skin test positive human sera, or immunized BALB/c mouse sera with the crude extract adsorbed to alum. IgE-immunoblot analysis showed major IgE-reacting protein band patterns, which reacted with more than 50% of the skin test positive human sera, at 110, 80, 73, 46, 40, 37, 34, and 31 kDa. The reactive band patterns were largely similar between skin test positive humans and immune BALB/c mice. However, the bands of 55, 31, 27, 26, 24, and 23 kDa were found only in sensitized humans, but not in immunized mice.

Citations

Citations to this article as recorded by

Les allergènes croisants des insectes comestibles
A. Barre, E. Velazquez, A. Delplanque, S. Caze-Subra, F. Bienvenu, J. Bienvenu, H. Benoist, P. Rougé
Revue Française d'Allergologie.2016; 56(7-8): 522. CrossRef
Haemoglobin, a new major allergen of Anisakis simplex
Juan González-Fernández, Alvaro Daschner, Natalie E. Nieuwenhuizen, Andreas L. Lopata, Consolación De Frutos, Ana Valls, Carmen Cuéllar
International Journal for Parasitology.2015; 45(6): 399. CrossRef
An Asiatic Chironomid in Brazil: morphology, DNA barcode and bionomics
Gizelle Amora, Neusa Hamada, Lívia Maria Fusari, Vanderly Andrade-Souza
ZooKeys.2015; 514: 129. CrossRef
L’effet inflammatoire de l’extrait brut de Phaenopsectra flavipes (Diptera : Chironomidae) du Nord-Est algérien, chez un modèle murin (Mus musculus)
Z. Bensakhri, K. Zerguine, I. Bouguenoun, D. Bendjeddou
Revue Française d'Allergologie.2014; 54(7): 485. CrossRef
Six new and two newly recorded species of Chironomidae (Insecta: Diptera) in Korea
Han Il Ree
Entomological Research.2013; 43(6): 322. CrossRef
Two New and Four Unrecorded Species of Chironomidae (Diptera) in Korea
Han-Il Ree, Sung-Hyun Nam, Kyoung-Yong Jeong
Animal Systematics, Evolution and Diversity.2012; 28(1): 2. CrossRef
Eight New and Four Newly Recorded Species of Chironomidae (Insecta: Diptera) from Korea
Han Il Ree
Animal Systematics, Evolution and Diversity.2012; 28(4): 241. CrossRef
Household Arthropod Allergens in Korea
Tai-Soon Yong, Kyoung Yong Jeong
The Korean Journal of Parasitology.2009; 47(Suppl): S143. CrossRef
Molecular Cloning and Characterization of Tropomyosin, a Major Allergen of Chironomus kiiensis , a Dominant Species of Nonbiting Midges in Korea
Kyoung Yong Jeong, Hye-Yung Yum, In-Yong Lee, Han-Il Ree, Chein-Soo Hong, Dong Soo Kim, Tai-Soon Yong
Clinical and Vaccine Immunology.2004; 11(2): 320. CrossRef

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Monoclonal antibodies to recombinant Der p 2, a major house dust mite allergen: specificity, epitope analysis and development of two-site capture ELISA: Tai-Soon Yong, Sang-Mi Lee, Gab-Man Park, In-Yong Lee, Han-Il Ree, Kyung-Sup Kim, Sang-Hwan Oh, Jung-Won Park, Chein-Soo Hong; Korean J Parasitol 1999;37(3):163-169.
Published online September 20, 1999; DOI: https://doi.org/10.3347/kjp.1999.37.3.163

Abstract
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House dust mite allergens have been well established as sensitizing agents that are important in the induction of allergic diseases. In order to analyze epitopes of the allergen and to develop a quantitative method of the allergen exposure, monoclonal antibodies against a recombinant Der p 2 (rDer p 2), one of the major allergens of Dermatophagoides pteronyssinus, were produced. Four monoclonal antibodies produced were species-specific and did not cross-react to the D. farinae crude extract. Two of the monoclonal antibodies were found to be IgG1 and the others were IgM. For the analysis of epitopes, a Der p 2 cDNA encoding 126 amino acids (aa) was dissected into three fragments with several overlapping peptides, A (aa residues 1-49), B (44-93), and C fragment (84-126). Three monoclonal antibodies showed reactivities to the recombinant B fragment and to the full-length rDer p 2, but one monoclonal antibody reacted only with the full-length rDer p 2. Two-site capture ELISA was developed using two different monoclonal antibodies for quantitating Der p 2 in house dust. The sensitivity limit was 4 ng/ml with rDer p 2 and 8 ?g/ml with the D. pteronyssinus crude extract. The result suggested that the assay using monoclonal antibodies against rDer p 2 could be useful for the environmental studies and for the standardization of mite allergen extracts.

Citations

Citations to this article as recorded by

Determination of immunogenic epitopes in major house dust mite allergen, Der p 2, via nanoallergens
Jenna Sjoerdsma, Franklin Mejia, Basar Bilgicer
Annals of Allergy, Asthma & Immunology.2022; 129(2): 231. CrossRef
Mapping Mimotopes for House Dust Mite Allergen Der f 7 Using a Specific Monoclonal Antibody
Jianglong Peng, Hao Yin, Ying Zhou, Haoyuan Jia, Yubao Cui
Protein & Peptide Letters.2019; 26(3): 184. CrossRef
Expression and purification of a major allergen, Pla a 1, from Platanus acerifolia pollen and the preparation of its monoclonal antibody
Wei-Wei Ni, Wen Huang, De-Qin Wu, Yan-Jun Zhou, Chun-Mei Ji, Meng-Da Cao, Miao Guo, Jin-Lu Sun, Ji-Fu Wei
Molecular Medicine Reports.2017; 16(3): 2887. CrossRef
Review on Ecology of House Dust Mites in Korea and Suggestion of a Standard Survey Method
Tai-Soon Yong, Kyoung-Yong Jeong
Pediatric Allergy and Respiratory Disease.2011; 21(1): 4. CrossRef
Monoclonal antibodies against recombinant Der f 3 reveal localization of Der f 3 in the gut and faecal pellets of Dermatophagoides farinae
Zheng-ke Zhan, Kun-mei Ji, Xiao-yu Liu, Zhi-gang Liu, Meng Li, Jia-jie Chen, Jia-na Li, Shi Qiu
Experimental and Applied Acarology.2010; 52(1): 63. CrossRef
Household Arthropod Allergens in Korea
Tai-Soon Yong, Kyoung Yong Jeong
The Korean Journal of Parasitology.2009; 47(Suppl): S143. CrossRef
Mimotopes identify conformational B-cell epitopes on the two major house dust mite allergens Der p 1 and Der p 2
Krisztina Szalai, Jan Fuhrmann, Tea Pavkov, Michael Scheidl, Julia Wallmann, Kira H. Brämswig, Susanne Vrtala, Otto Scheiner, Walter Keller, Jean-Marie Saint-Remy, Dirk Neumann, Isabella Pali-Schöll, Erika Jensen-Jarolim
Molecular Immunology.2008; 45(5): 1308. CrossRef
Monoclonal antibodies to recombinant Der f 2 and development of a two‐site ELISA sensitive to major Der f 2 isoallergen in Korea
K.Y. Jeong, H.S. Jin, S.H. Oh, C.‐S. Hong, I.‐Y. Lee, H.‐I. Ree, T.‐S. Yong
Allergy.2002; 57(1): 29. CrossRef
Monoclonal antibodies to recombinant Der f 2 and development of a two-site ELISA sensitive to major Der f 2 isoallergen in Korea
K.Y. Jeong, H.S. Jin, S.H. Oh, C.-S. Hong, I.-Y. Lee, H.-I. Ree, T.-S. Yong
Allergy.2002; 57(1): 29. CrossRef
Localization of Der f 2 in the gut and fecal pellets of Dermatophagoides farinae
K. Y. Jeong, I.‐Y. Lee, H.‐I. Ree, C.‐S. Hong, T.‐S. Yong
Allergy.2002; 57(8): 729. CrossRef
Localization of a major allergen, Der p 2, in the gut and faecal pellets of Dermatophagoides pteronyssinus
Park, Lee, Lee, Ree, Kim, Hong, Yong
Clinical & Experimental Allergy.2000; 30(9): 1293. CrossRef