A 22-year-old Thai man from the Northeast region presented with acute eye swelling, itching, and discharge on his left eye. He was suspected of having gnathostomiasis and treated with albendazole and prednisolone for 3 weeks. Nine months later, he was treated with high-dose oral prednisolone for the preliminary and differential diagnoses with thyroid-associated orbitopathy and lymphoma. He had been administered prednisolone intermittently over a few years. Then he developed a painless movable mass at the left upper eyelid and recurrent pseudotumor oculi was suspected. The surgical removal of the mass was performed. A white pseudosegmented worm revealed a definite diagnosis of ocular sparganosis by a plerocercoid larva. Molecular diagnosis of the causative species was made based on the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene. Proper technique of extraction and amplification of short fragments DNA from formalin-fixed paraffin-embedded tissue successfully identified parasite species. The result from the sequencing of the PCR-amplified cox1 fragments in this study showed 99.0% sequence homology to Spirometra ranarum. This is the first report of S. ranarum in Thailand.
Citations
Citations to this article as recorded by
Molecular Characterization of Spirometra erinaceieuropaei from Jungle Cat (Felis chaus) in North of Iran Mahboobeh Salimi, Meysam Sharifdini, Eshrat Beigom Kia Acta Parasitologica.2024; 69(1): 574. CrossRef
Sparganosis S. B. Chuelov, A. L. Rossina CHILDREN INFECTIONS.2024; 23(1): 44. CrossRef
Sparganosis in the Indian Sub-continent and the Middle East Yukifumi Nawa, Mio Tanaka, Masahide Yoshikawa Parasites, Hosts and Diseases.2024; 62(3): 263. CrossRef
Medical Parasitology Taxonomy Update, June 2020–June 2022 Blaine A. Mathison, Richard S. Bradbury, Bobbi S. Pritt, Romney M. Humphries Journal of Clinical Microbiology.2023;[Epub] CrossRef
Parasites, champignons et atteintes oculaires Hélène Yera, Marie-Fleur Durieux, Dominique Chabasse, Marie-Laure Dardé Revue Francophone des Laboratoires.2023; 2023(552): 44. CrossRef
Sparganosis parasitic tumor: Resectability and postoperative outcome, and analysis of cases from an endemic area in Indochina Amnuay Kleebayoon, Viroj Wiwanitkit Formosan Journal of Surgery.2023; 56(5): 160. CrossRef
An annotated checklist of the eukaryotic parasites of humans, exclusive of fungi and algae Blaine A. Mathison, Sarah G. H. Sapp ZooKeys.2021; 1069: 1. CrossRef
First
Prev
