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"Xuenong Luo"

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"Xuenong Luo"

Case Report

Infection of Taenia asiatica in a Bai Person in Dali, China
Li Wang, Xuenong Luo, Junling Hou, Aijiang Guo, Shaohua Zhang, Hailong Li, Xuepeng Cai
Korean J Parasitol 2016;54(1):67-70.
Published online February 26, 2016
DOI: https://doi.org/10.3347/kjp.2016.54.1.67
We report here a human case of Taenia asiatica infection which was confirmed by genetic analyses in Dali, China. A patient was found to have symptoms of taeniasis with discharge of tapeworm proglottids. By sequencing of the mitochondrial cytochrome c oxidase subunit 1 (cox1) gene, we observed nucleotide sequence identity of 99% with T. asiatica and 96% with T. saginata. Using the cytochrome b (cytb) gene, 99% identity with T. asiatica and 96% identity with T. saginata were found. Our findings suggest that taeniasis of people in Dali, China may be mainly caused by T. asiatica.

Citations

Citations to this article as recorded by  Crossref logo
  • Case Report: Molecular Diagnosis Revealing an Intestinal Infection of a Hybridized Tapeworm (Taenia saginata and Taenia asiatica) to Human in Yunnan, China
    Kan-Kan Chu, Ye Qiu, Ce-Heng Liao, Zhi You, Zuo-Shun He, Wen Fang, Hong-Ying Li, Peter Daszak, Jun-Jie Hu, Yun-Zhi Zhang, Xing-Yi Ge
    Frontiers in Gastroenterology.2022;[Epub]     CrossRef
  • Identification and molecular characterization of exosome-like vesicles derived from the Taenia asiatica adult worm
    Panhong Liang, Li Mao, Shaohua Zhang, Xiaola Guo, Guangxue Liu, Lijie Wang, Junling Hou, Yadong Zheng, Xuenong Luo
    Acta Tropica.2019; 198: 105036.     CrossRef
  • Porcine cysticercosis (Taenia solium and Taenia asiatica): mapping occurrence and areas potentially at risk in East and Southeast Asia
    Uffe Christian Braae, Nguyen Manh Hung, Fadjar Satrija, Virak Khieu, Xiao-Nong Zhou, Arve Lee Willingham
    Parasites & Vectors.2018;[Epub]     CrossRef
  • 12,271 View
  • 136 Download
  • 3 Web of Science
  • Crossref
Original Articles
Codon Usage Bias and Determining Forces in Taenia solium Genome
Xing Yang, Xusheng Ma, Xuenong Luo, Houjun Ling, Xichen Zhang, Xuepeng Cai
Korean J Parasitol 2015;53(6):689-697.
Published online December 31, 2015
DOI: https://doi.org/10.3347/kjp.2015.53.6.689
The tapeworm Taenia solium is an important human zoonotic parasite that causes great economic loss and also endangers public health. At present, an effective vaccine that will prevent infection and chemotherapy without any side effect remains to be developed. In this study, codon usage patterns in the T. solium genome were examined through 8,484 protein-coding genes. Neutrality analysis showed that T. solium had a narrow GC distribution, and a significant correlation was observed between GC12 and GC3. Examination of an NC (ENC vs GC3s)-plot showed a few genes on or close to the expected curve, but the majority of points with low-ENC (the effective number of codons) values were detected below the expected curve, suggesting that mutational bias plays a major role in shaping codon usage. The Parity Rule 2 plot (PR2) analysis showed that GC and AT were not used proportionally. We also identified 26 optimal codons in the T. solium genome, all of which ended with either a G or C residue. These optimal codons in the T. solium genome are likely consistent with tRNAs that are highly expressed in the cell, suggesting that mutational and translational selection forces are probably driving factors of codon usage bias in the T. solium genome.

Citations

Citations to this article as recorded by  Crossref logo
  • Distinct codon usage signatures reflecting evolutionary and pathogenic adaptation in the Acinetobacter baumannii complex
    Ujwal Dahal, Anuj Sharma, Karan Paul, Anu Bansal, Shelly Gupta
    European Journal of Clinical Microbiology & Infectious Diseases.2025; 44(11): 2803.     CrossRef
  • Evolution of codon usage in Taenia saginata genomes and its impact on the host
    Siddiq Ur Rahman, Hassan Ur Rehman, Inayat Ur Rahman, Muazzam Ali Khan, Fazli Rahim, Hamid Ali, Dekun Chen, Wentao Ma
    Frontiers in Veterinary Science.2023;[Epub]     CrossRef
  • Comparative analysis of codon usage patterns and phylogenetic implications of five mitochondrial genomes of the genus Japanagallia Ishihara, 1955 (Hemiptera, Cicadellidae, Megophthalminae)
    Min Li, Jiajia Wang, Renhuai Dai, Guy Smagghe, Xianyi Wang, Siying You
    PeerJ.2023; 11: e16058.     CrossRef
  • Codon Usage is Influenced by Compositional Constraints in Genes Associated with Dementia
    Taha Alqahtani, Rekha Khandia, Nidhi Puranik, Ali M. Alqahtani, Yahia Alghazwani, Saad Ali Alshehri, Kumarappan Chidambaram, Mohammad Amjad Kamal
    Frontiers in Genetics.2022;[Epub]     CrossRef
  • Analysis of codon usage bias of lumpy skin disease virus causing livestock infection
    Siddiq Ur Rahman, Hassan Ur Rehman, Inayat Ur Rahman, Abdur Rauf, Abdulrahman Alshammari, Metab Alharbi, Noor ul Haq, Hafiz Ansar Rasul Suleria, Sayed Haidar Abbas Raza
    Frontiers in Veterinary Science.2022;[Epub]     CrossRef
  • Codon usage pattern in Gnetales evolved in close accordance with the Gnetifer hypothesis
    Aasim Majeed, Harpreet Kaur, Amitozdeep Kaur, Sreemoyee Das, Josepheena Joseph, Pankaj Bhardwaj
    Botanical Journal of the Linnean Society.2021; 196(4): 423.     CrossRef
  • Analysis of codon usage bias in mitochondrial CO gene among platyhelminthes
    Gulshana A. Mazumder, Arif Uddin, Supriyo Chakraborty
    Molecular and Biochemical Parasitology.2021; 245: 111410.     CrossRef
  • Genetic evolution and codon usage analysis of NKX-2.5 gene governing heart development in some mammals
    Arup Kr. Malakar, Binata Halder, Prosenjit Paul, Himangshu Deka, Supriyo Chakraborty
    Genomics.2020; 112(2): 1319.     CrossRef
  • Selection constraints determine preference for A/U-ending codons in Taxus contorta
    Aasim Majeed, Harpreet Kaur, Pankaj Bhardwaj
    Genome.2020; 63(4): 215.     CrossRef
  • Analysis of codon usage pattern of mitochondrial ND genes in Platyhelminthes
    Gulshana A. Mazumder, Arif Uddin, Supriyo Chakraborty
    Molecular and Biochemical Parasitology.2020; 238: 111294.     CrossRef
  • Compositional Analysis of Flatworm Genomes Shows Strong Codon Usage Biases Across All Classes
    Guillermo Lamolle, Santiago Fontenla, Gastón Rijo, Jose F. Tort, Pablo Smircich
    Frontiers in Genetics.2019;[Epub]     CrossRef
  • Compositional bias coupled with selection and mutation pressure drives codon usage in Brassica campestris genes
    Prosenjit Paul, Arup Kumar Malakar, Supriyo Chakraborty
    Food Science and Biotechnology.2018; 27(3): 725.     CrossRef
  • Whole genome analysis of codon usage in Echinococcus
    Lucas L. Maldonado, Georgina Stegmayer, Diego H. Milone, Guilherme Oliveira, Mara Rosenzvit, Laura Kamenetzky
    Molecular and Biochemical Parasitology.2018; 225: 54.     CrossRef
  • Comprehensive Analysis of Codon Usage on Rabies Virus and Other Lyssaviruses
    Xu Zhang, Yuchen Cai, Xiaofeng Zhai, Jie Liu, Wen Zhao, Senlin Ji, Shuo Su, Jiyong Zhou
    International Journal of Molecular Sciences.2018; 19(8): 2397.     CrossRef
  • Codon Usage Patterns of Tyrosinase Genes in Clonorchis sinensis
    Young-An Bae
    The Korean Journal of Parasitology.2017; 55(2): 175.     CrossRef
  • 12,480 View
  • 130 Download
  • 15 Web of Science
  • Crossref
Sequence Analysis and Molecular Characterization of Wnt4 Gene in Metacestodes of Taenia solium
Junling Hou, Xuenong Luo, Shuai Wang, Cai Yin, Shaohua Zhang, Xueliang Zhu, Yongxi Dou, Xuepeng Cai
Korean J Parasitol 2014;52(2):163-168.
Published online April 18, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.2.163

Wnt proteins are a family of secreted glycoproteins that are evolutionarily conserved and considered to be involved in extensive developmental processes in metazoan organisms. The characterization of wnt genes may improve understanding the parasite's development. In the present study, a wnt4 gene encoding 491amino acids was amplified from cDNA of metacestodes of Taenia solium using reverse transcription PCR (RT-PCR). Bioinformatics tools were used for sequence analysis. The conserved domain of the wnt gene family was predicted. The expression profile of Wnt4 was investigated using real-time PCR. Wnt4 expression was found to be dramatically increased in scolex evaginated cysticerci when compared to invaginated cysticerci. In situ hybridization showed that wnt4 gene was distributed in the posterior end of the worm along the primary body axis in evaginated cysticerci. These findings indicated that wnt4 may take part in the process of cysticerci evagination and play a role in scolex/bladder development of cysticerci of T. solium.

Citations

Citations to this article as recorded by  Crossref logo
  • Transcriptome of Taenia solium during in vitro cyst activation and initial growth into the tapeworm stage
    David Castaneda-Carpio, Renzo Gutierrez-Loli, Jose Maravi-Jaime, Segundo W. Del Aguila, Valeria Villar-Davila, Luz M. Moyano, Rafael Tapia-Limonchi, Stella M. Chenet, Cristina Guerra-Giraldez
    Scientific Data.2025;[Epub]     CrossRef
  • The significant sex-biased expression pattern of Sp-Wnt4 provides novel insights into the ovarian development of mud crab (Scylla Paramamosain)
    Ardavan Farhadi, Shaobin Fang, Yin Zhang, Wenxiao Cui, Huan Fang, Mhd Ikhwanuddin, Hongyu Ma
    International Journal of Biological Macromolecules.2021; 183: 490.     CrossRef
  • Transcriptomic profile of two developmental stages of the cestode parasite Mesocestoides corti
    T. Basika, G.P. Paludo, F.M. Araujo, A.C. Salim, F. Pais, L. Maldonado, N. Macchiaroli, J. Camargo de Lima, M. Rosenzvit, G.C. Oliveira, L. Kamenetzky, H.B. Ferreira
    Molecular and Biochemical Parasitology.2019; 229: 35.     CrossRef
  • Comparative Transcriptomic Analysis of the Larval and Adult Stages of Taenia pisiformis
    Shaohua Zhang
    Genes.2019; 10(7): 507.     CrossRef
  • Molecular and biochemical characterization of Taenia solium α-enolase
    Shaohua Zhang, Yanan You, Xuenong Luo, Yadong Zheng, Xuepeng Cai
    Veterinary Parasitology.2018; 254: 36.     CrossRef
  • Transcriptomic analysis of the larva Taenia multiceps
    W.H. Li, N.Z. Zhang, L. Yue, Y. Yang, L. Li, H.B. Yan, T.T. Li, Z.G. Qu, W.Z. Jia, B.Q. Fu
    Research in Veterinary Science.2017; 115: 407.     CrossRef
  • 10,692 View
  • 81 Download
  • 6 Web of Science
  • Crossref