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Case Report

A Case of Ectopic Peritoneal Paragonimiasis Mimicking Diverticulitis or Abdominal Abscess
Min Jae Kim, Sung-Han Kim, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Jun Hee Woo, Yong Sik Yoon, Kyung Won Kim, Jaeeun Cho, Jong-Yil Chai, Yong Pil Chong
Korean J Parasitol 2017;55(3):313-317.
Published online June 30, 2017
DOI: https://doi.org/10.3347/kjp.2017.55.3.313
Paragonimiasis is a parasitic disease caused by Paragnonimus species. The primary site of infection is the lung, and extrapulmonary involvement is also reported. When infected with Paragonimus westermani, which is the dominant species in Korea, the central nervous system is frequently involved along with the liver, intestine, peritoneal cavity, retroperitoneum, and abdominal wall. Ectopic paragonimiasis raises diagnostic challenge since it is uncommon and may be confused with malignancy or other inflammatory diseases. Here, we report an ectopic paragonimiasis case initially presented with recurrent abdominal pain. The patient developed abdominal pain 3 times for the previous 3 years and the computed tomography (CT) of the abdomen revealed fluid collection with wall enhancement. Recurrent diverticulitis was initially suspected and part of the ascending colon was resected. However, the specimen showed intact colon wall without evidence of diverticulitis and multiple parasite eggs and granulomas were found instead. The size of about 70 μm, the presence of an operculum and relatively thick egg shell suggested eggs of Paragonimus species. With appropriate exposure history and a positive antibody test, the definitive diagnosis was made as peritoneal paragonimiasis.

Citations

Citations to this article as recorded by  Crossref logo
  • A case report of Paragonimus infection diagnosed by medicine thoracoscopy
    Xia Wu, Zhengfu Li, Dan Yang, Zhangli Peng, Nana Li, Yuanbo Lan, Ling Chen
    Infection, Genetics and Evolution.2025; 134: 105791.     CrossRef
  • Intra-abdominal paragonimiasis presenting as abscesses: A case report
    Haidong Zhang, Mingchun Mu, Xin He, Yuan Yin
    Asian Journal of Surgery.2023; 46(2): 1004.     CrossRef
  • Crustaceans (shrimp, crab, and lobster): A comprehensive review of their potential health hazards and detection methods to assure their biosafety
    Mohamed A. Farag, Somaia T. Mansour, Roua A. Nouh, Amira R. Khattab
    Journal of Food Safety.2023;[Epub]     CrossRef
  • Intra-abdominal paragonimiasis abscess: A note on rare recurrent acute abdomen disease
    Pathum Sookaromdee, Viroj Wiwanitkit
    Formosan Journal of Surgery.2023; 56(6): 200.     CrossRef
  • A case of paragonimiasis inducing bilateral pneumothorax with lung and liver involvement
    Ji Sung Ha, Jang Young Lee, Won Young Sung, Sang Won Seo, Won Suk Lee
    Asian Cardiovascular and Thoracic Annals.2022; 30(3): 339.     CrossRef
  • Ectopic peritoneal paragonimiasis mimicking tuberculous peritonitis: A care report
    Jung Woo Choi, Chang Min Lee, Seong Je Kim, Se In Hah, Ji Yoon Kwak, Hyun Chin Cho, Chang Yoon Ha, Woon Tae Jung, Ok Jae Lee
    World Journal of Clinical Cases.2022; 10(16): 5359.     CrossRef
  • General overview of the current status of human foodborne trematodiasis
    Jong-Yil Chai, Bong-Kwang Jung
    Parasitology.2022; 149(10): 1262.     CrossRef
  • One delayed diagnosis of paragonimiasis case and literature review
    Luxia Kong, Lijuan Hua, Qian Liu, Chen Bao, Jiannan Hu, Shuyun Xu
    Respirology Case Reports.2021;[Epub]     CrossRef
  • Laparoscopic excision for ectopic peritoneal paragonimiasis mimicking a gastric duplication cyst: A case report
    Chul Kyu Roh, Min Jung Jung
    Annals of Medicine and Surgery.2021; 69: 102754.     CrossRef
  • A case of group infections with Paraginimus species in Henan, Central China
    Wei-qi Chen, Yan Deng, Ya-lan Zhang, Lin Ai, Jia-xu Chen, Xi-meng Lin, Xiao-bo Du, Peng Li, Rui-min Zhou, Cheng-yun Yang, Ying Liu, Hong-wei Zhang, Bian-li Xu, Yu-ling Zhao
    Acta Tropica.2020; 202: 105111.     CrossRef
  • Paragonimus westermani infection manifesting as a pulmonary cavity and adrenal gland mass: A case report
    Yong Shik Kwon, Hye Won Lee, Hyun Jung Kim
    Journal of Infection and Chemotherapy.2019; 25(3): 200.     CrossRef
  • A Paragonimiasis Mimicking Gastric Submucosal Tumor
    Hyeri Seok, Tae Sung Sohn, Kyong Ran Peck
    Journal of Korean Medical Science.2019;[Epub]     CrossRef
  • Simultaneous Paragonimus infection involving the breast and lung: A case report
    Moon Young Oh, Ajung Chu, Jeong Hwan Park, Jong Yoon Lee, Eun Youn Roh, Young Jun Chai, Ki-Tae Hwang
    World Journal of Clinical Cases.2019; 7(24): 4292.     CrossRef
  • 10,308 View
  • 208 Download
  • 13 Web of Science
  • Crossref
Brief Communications
Influence of 120 kDa Pyruvate:Ferredoxin Oxidoreductase on Pathogenicity of Trichomonas vaginalis
Hyun-Ouk Song
Korean J Parasitol 2016;54(1):71-74.
Published online February 26, 2016
DOI: https://doi.org/10.3347/kjp.2016.54.1.71
Trichomonas vaginalis is a flagellate protozoan parasite and commonly infected the lower genital tract in women and men. Iron is a known nutrient for growth of various pathogens, and also reported to be involved in establishment of trichomoniasis. However, the exact mechanism was not clarified. In this study, the author investigated whether the 120 kDa protein of T. vaginalis may be involved in pathogenicity of trichomonads. Antibodies against 120 kDa protein of T. vaginalis, which was identified as pyruvate:ferredoxin oxidoreductase (PFOR) by peptide analysis of MALDI-TOF-MS, were prepared in rabbits. Pretreatment of T. vaginalis with anti-120 kDa Ab decreased the proliferation and adherence to vaginal epithelial cells (MS74) of T. vaginalis. Subcutaneous tissue abscess in anti-120 kDa Ab-treated T. vaginalis-injected mice was smaller in size than that of untreated T. vaginalis-infected mice. Collectively, the 120 kDa protein expressed by iron may be involved in proliferation, adhesion to host cells, and abscess formation, thereby may influence on the pathogenicity of T. vaginalis.

Citations

Citations to this article as recorded by  Crossref logo
  • Trichomonas vaginalis acid sphingomyelinases' theoretical structural analysis shows substrate binding diversity related to protein flexibility and mobility
    Ana Laura Medina-Nieto, Sairy Yarely Andrade-Guillen, Fátima Berenice Ramírez-Montiel, Fátima Tornero-Gutiérrez, José A. Martínez-Álvarez, Ángeles Rangel-Serrano, Itzel Páramo-Pérez, Naurú Idalia Vargas-Maya, Javier de la Mora, Claudia Leticia Mendoza-Mac
    Computational Biology and Chemistry.2026; 120: 108601.     CrossRef
  • Antiparasitic activity of the iron-containing milk protein lactoferrin and its potential derivatives against human intestinal and blood parasites
    Namrata Anand
    Frontiers in Parasitology.2024;[Epub]     CrossRef
  • Genetic Variability of the Internal Transcribed Spacer and Pyruvate:Ferredoxin Oxidoreductase Partial Gene of Trichomonas vaginalis from Female Patients
    Fernando Martinez-Hernandez, Fabiola Sanchez-Aguillon, Joel Martinez-Ocaña, Nelly Raquel Gonzalez-Arenas, Mirza Romero-Valdovinos, Eduardo Lopez-Escamilla, Pablo Maravilla, Guiehdani Villalobos
    Microorganisms.2023; 11(9): 2240.     CrossRef
  • Pyruvate: Ferredoxin oxidoreductase is involved in IgA-related microbiota dysbiosis and intestinal inflammation
    Kairuo Wang, Yixuan Guo, Yuanyuan Liu, Xiao Cui, Xiang Gu, Lixiang Li, Yanqing Li, Ming Li
    Frontiers in Immunology.2022;[Epub]     CrossRef
  • Microbiota in vaginal health and pathogenesis of recurrent vulvovaginal infections: a critical review
    Namarta Kalia, Jatinder Singh, Manpreet Kaur
    Annals of Clinical Microbiology and Antimicrobials.2020;[Epub]     CrossRef
  • New light on ancient enzymes – in vitro CO2 Fixation by Pyruvate Synthase of Desulfovibrio africanus and Sulfolobus acidocaldarius
    Andreas Witt, Roberta Pozzi, Stephan Diesch, Oliver Hädicke, Hartmut Grammel
    The FEBS Journal.2019; 286(22): 4494.     CrossRef
  • Humoral and T cell–mediated immune response against trichomoniasis
    M. Nemati, N. Malla, M. Yadav, H. Khorramdelazad, A. Jafarzadeh
    Parasite Immunology.2018;[Epub]     CrossRef
  • A Cell Surface Aggregation-Promoting Factor from Lactobacillus gasseri Contributes to Inhibition of Trichomonas vaginalis Adhesion to Human Vaginal Ectocervical Cells
    Niha Phukan, Anna E. S. Brooks, Augusto Simoes-Barbosa, John H. Adams
    Infection and Immunity.2018;[Epub]     CrossRef
  • Can the pyruvate: ferredoxin oxidoreductase (PFOR) gene be used as an additional marker to discriminate among Blastocystis strains or subtypes?
    Patricia Alarcon-Valdes, Guiehdani Villalobos, Williams Arony Martinez-Flores, Eduardo Lopez-Escamilla, Nelly Raquel Gonzalez-Arenas, Mirza Romero-Valdovinos, Fernando Martinez-Hernandez, Jonnathan Guadalupe Santillan-Benitez, Pablo Maravilla
    Parasites & Vectors.2018;[Epub]     CrossRef
  • Clostridium acetobutylicum grows vegetatively in a biofilm rich in heteropolysaccharides and cytoplasmic proteins
    Dong Liu, Zhengjiao Yang, Yong Chen, Wei Zhuang, Huanqing Niu, Jinglan Wu, Hanjie Ying
    Biotechnology for Biofuels.2018;[Epub]     CrossRef
  • 9,630 View
  • 93 Download
  • 10 Web of Science
  • Crossref
The MAK16 Gene of Entamoeba histolytica and Its Identification in Isolates from Patients
Mar?a del Pilar Cris?stomo-V?zquez, V?ctor Alberto Marevelez-Acosta, Andr?s Flores-Luna, Enedina Jim?nez-Cardoso
Korean J Parasitol 2014;52(4):429-433.
Published online August 29, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.4.429

To identify sequences of Entamoeba histolytica associated with the development of amebic liver abscess (ALA) in hamsters, subtractive hybridization of cDNA from E. histolytica HM-1:IMSS under 2 growth conditions was performed: 1) cultured in axenic medium and 2) isolated from experimental ALA in hamsters. For this procedure, 6 sequences were obtained. Of these sequences, the mak16 gene was selected for amplification in 29 cultures of E. histolytica isolated from the feces of 10 patients with intestinal symptoms and 19 asymptomatic patients. Only 5 of the 10 isolates obtained from symptomatic patients developed ALA and amplified the mak16 gene, whereas the 19 isolates from asymptomatic patients did not amplify the mak16 gene nor did they develop ALA. Based on the results of Fisher's exact test (P<0.001), an association was inferred between the presence of the mak16 gene of E. histolytica and the ability to develop ALA in hamsters and with the patient's symptoms (P=0.02). The amplification of the mak16 gene suggests that it is an important gene in E. histolytica because it was present in the isolates from hamsters that developed liver damage.

Citations

Citations to this article as recorded by  Crossref logo
  • Differential alternative splicing landscape identifies potentially functional RNA binding proteins in early embryonic development in mammals
    Jianhua Chen, Yanni He, Liangliang Chen, Tian Wu, Guangping Yang, Hui Luo, Saifei Hu, Siyue Yin, Yun Qian, Hui Miao, Na Li, Congxiu Miao, Ruizhi Feng
    iScience.2024; 27(3): 109104.     CrossRef
  • Identification of two transcription factors that work coordinately to regulate early development in Entamoeba
    Daniela Lozano-Amado, Upinder Singh, Laura J. Knoll
    mBio.2024;[Epub]     CrossRef
  • Proteome analysis of excretory-secretory proteins of Entamoeba histolytica HM1:IMSS via LC–ESI–MS/MS and LC–MALDI–TOF/TOF
    Jorim Anak Ujang, Soon Hong Kwan, Mohd Nazri Ismail, Boon Huat Lim, Rahmah Noordin, Nurulhasanah Othman
    Clinical Proteomics.2016;[Epub]     CrossRef
  • 8,667 View
  • 78 Download
  • 3 Web of Science
  • Crossref
Characterization of YS-27, an axenic Korean strain of Entamoeba histolytica
Soon-Jung Park, Tai-Soon Yong, Jae-Kyung Chang, Kyung-Il Im, Chin-Thack Soh
Korean J Parasitol 1999;37(1):59-62.
Published online March 31, 1999
DOI: https://doi.org/10.3347/kjp.1999.37.1.59

Characterization of YS-27, an axenic Entamoeba strain, was performed by three different laboratory methods. Zymodeme analysis using starch gel electrophoresis and PCR with species-specific primers showed that YS-27 is a pathogenic Entamoeba which belongs to the group II zymodeme. Pathogenicity of YS-27 was further confirmed by observing the formation of liver abscess in Mongolian gerbils. These results showed that YS-27 is E. hisolytica.

  • 7,735 View
  • 54 Download