Parasites, Hosts and Diseases

"endemic"

Original Article

Performance validation of the BD MAX Enteric Parasite Panel using simulated samples in low endemic regions: Bosung Park, Eun Jeong Won, Heungsup Sung, Mi-Na Kim; Parasites Hosts Dis 2025;63(1):50-56.
Published online February 25, 2025; DOI: https://doi.org/10.3347/PHD.24071

Abstract
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Molecular diagnostics are essential for detecting intestinal parasites, but evaluating clinical samples from low endemic areas, including Korea, is challenging. We tested the performance of the BD MAX Enteric Parasite Panel in simulated samples for clinical use. Simulated samples were prepared with residual stool samples to confirm the diagnostic performance of the kits. Standard materials for Cryptosporidium parvum, Giardia lamblia, and Entamoeba histolytica were obtained for assessment. Limit of detection was determined by diluting standard materials into multiple concentrations and testing each in duplicate. Repeatability was assessed by retesting all samples twice. Accuracy was evaluated by comparing BD MAX System results with intended results. The limit of detection values obtained using standard materials were 781 cysts/ml, 6,250 oocysts/ml, and 125 DNA copies/ml for G. lamblia, C. parvum, and E. histolytica, respectively. Simulated G. lamblia-positive stool samples with concentrations above 6,250 cysts/ml consistently yielded positive results (100% concordance). However, C. parvum-positive stool samples at 6,250 oocysts/ml showed 50% concordance initially and 75% after retesting. At 62,500 oocysts/ml, the concordance rates were 89% initially and 100% after retesting. Overall agreement was 95.2%, but that for C. parvum was relatively low (82.4%). The diagnostic performances were 87.8% of sensitivity and 100% of specificity. Despite the limited clinical samples, BD MAX Enteric Parasite Panel showed good performance for clinical use, and spiked samples proved useful for evaluating protozoan PCR in low-incidence regions.

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Mini Review

Infection characteristics of Metagonimus species (Digenea: Heterophyidae) metacercariae in fish from major rivers of Korea: Woon-Mok Sohn; Parasites Hosts Dis 2024;62(1):1-29.
Published online February 23, 2024; DOI: https://doi.org/10.3347/PHD.23096

This article analyzed the infection characteristics of metacercariae of Metagonimus spp. (MsMc) in fish from 9 major water systems in Korea. A total of 19,568 fish in 87 species were examined over a period of 10 years (2011–2020). MsMc were detected in fish from all 44 survey areas in 9 water systems. Most of the surveyed sites showed very low and low infection levels (66.7%), while 33.3% of the areas, such as Tamjin-gang and Seomjin-gang, revealed moderate and high infection levels. High endemicity depends on the abundance of susceptible fish species, especially sweet smelt (Plecoglosus altivelis). The susceptibility index (SI) with MsMc in index fish, Zacco spp., was very low and low levels in 62.0%, moderate in 28.0%, and high in 10.0% regions. The SI was highest in the following order: Yeongam-cheon (283.8), Hoeng-cheon (192.3), Togyo-jeosuji (131.2), Deokcheon-gang (119.1), and Joyang-gang (106.3). The recent infection status of MsMc in P. altivelis was analyzed by the survey localities. In addition, except for P. altivelis, 9 fish species were highly infected with MsMc in some survey areas, including Zacco platypus, Z. koreanus, Z. temminckii, Opsariichthys uncirostris, Rhynchocypris oxycephalus, Carassius auratus, Acheilognathus rhombeus, Onchorhynchus masou, and Tribolodon hakonensis. In Korea, 74 fish species (15 families) are collectively listed as second intermediate hosts of Metagonimus spp. This review provides several novel characteristics of MsMc infection and clarifies the fish species of second intermediate host of Metagonimus spp. in this country.

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Detection of intestinal parasites in leopard cat fecal samples using shotgun metagenomics
Jun Ho Choi, Singeun Oh, Myung-hee Yi, Dongjun Kang, Du-Yeol Choi, Xavier Chavarria, Arwa Shatta, Yoon Hee Cho, Seongjun Choe, Seung-Hun Lee, Ju Yeong Kim
Parasites, Hosts and Diseases.2025; 63(4): 349. CrossRef

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Original Articles

Status of Helminthic Infections in Residents around River Basins in the Republic of Korea for 10 Years (2011-2020): Myoung-Ro Lee, Hee-Eun Shin, Seon-Ok Back, Young-Ju Lee, Hee-Il Lee, Jung-Won Ju; Korean J Parasitol 2022;60(3):187-193.
Published online June 30, 2022; DOI: https://doi.org/10.3347/kjp.2022.60.3.187

Abstract
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The positive rate of Clonorchis sinensis is the highest among intestinal parasites in the Republic of Korea (Korea). More than 1.2 million people were at risk of C. sinensis infection in Korea in 2012. An intensive control program is being implemented for residents of the 5 major river basins to reduce helminthic infections, including C. sinensis infection. This study evaluated the continuous intensive control program for parasitic diseases including clonorchiasis in areas near the 5 major river basins in Korea over the past 10 years (2011-2020). A total of 335,020 fecal samples (one sample per resident) prepared by the modified sedimentation technic were microscopically examined. Those who expelled helminth eggs were treated with anthelmintics through local health centers and re-examined 3 months later. The overall positive rate of helminths egg was 7.1%. The annual positive rates were dramatically decreased from 14.4% (2011) to 5.9% (2020). The egg positive rate was highest in C. sinensis (5.3%), followed by heterophyid flukes (1.5%) and Trichuris trichiura (0.2%). The prevalence of C. sinensis was significantly higher in males (7.6%) than in females (3.7%), and the highest in the 50–59 years (7.0%) age group. Our results are beneficial to establish prevention and control policies against helminthiases including clonorchiasis in endemic areas in this country.

Citations

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Clonorchis sinensis and Cholangiocarcinoma
Eun-Min Kim, Sung-Tae Hong
Journal of Korean Medical Science.2025;[Epub] CrossRef
Multiparasitism in Spain in a Korean Visiting Friends and Relatives: Case Report and Review of Imported Cases of Clonorchis sinensis in Europe
Paola Cociancic, Jacklyn Comas, J. Guillermo Esteban
Clinical Case Reports.2025;[Epub] CrossRef
Assessing trends in clonorchiasis incidence via prescription data analysis in South Korea
Taeksang Lee, Jun Hyun Lee, Hanna Jin, Yun Kyung Lee, Hyun Beom Song
BMC Public Health.2025;[Epub] CrossRef
2023년 국내 장내기생충 감염 조사
명노 이, 정원 주, 선옥 백, 영주 이, 은솔 이, 희일 이
Public Health Weekly Report.2024; 17(28): 1227. CrossRef
Efficacy assessment of miltefosine and curcumin against Clonorchis sinensis infection
Soon-Ok Lee, Ki Back Chu, Keon-Woong Yoon, Gi-Deok Eom, Jie Mao, Hyeryon Lee, Joo Hwan No, Jin Ho Song, Sung-Jong Hong, Sung Soo Kim, Fu-Shi Quan, Audrey Odom John
Antimicrobial Agents and Chemotherapy.2024;[Epub] CrossRef
A novel kit for enrichment of fecal helminth eggs
Eunsol Lee, Seon-Ok Back, Young-Ju Lee, Jung-Won Ju, Hee-Il Lee, Myoung-Ro Lee
Parasites, Hosts and Diseases.2024; 62(3): 323. CrossRef
Age, period, and cohort effects of Clonorchis sinensis infection prevalence in the Republic of Korea: Insights and projections
Sung-mok Jung, Heewon Kang, Bong-Kwang Jung, Sejin Ju, Jung-Won Ju, Myoung-Ro Lee, Jong-hun Kim, Sung Hye Kim, Ran Wang
PLOS Neglected Tropical Diseases.2024; 18(10): e0012574. CrossRef
Risk factors for Clonorchis sinensis infections and control measures reinforced with focused interviews
Soon-Ok Lee, Fuhong Dai, Eun Joo Park, Yun Pyo Hong, Fu-Shi Quan, Jin-Ho Song, Sung-Jong Hong
Parasitology Research.2024;[Epub] CrossRef
2022년 유행지역 주민의 장내기생충 감염 조사
명노 이, 정원 주, 선옥 백, 영주 이, 희일 이
Public Health Weekly Report.2023; 16(32): 1131. CrossRef
2022년 국내 자연산 민물고기 간흡충 감염도 조사
명노 이, 정원 주, 선옥 백, 영주 이, 희일 이
Public Health Weekly Report.2023; 16(43): 1455. CrossRef
Relationship between Clonorchis sinensis Infection and Cholangiocarcinoma in Korea
Hwa Sun Kim, Ho-Woo Nam, Hye-Jin Ahn, Dongjae Kim, Yeong Hoon Kim
The Korean Journal of Parasitology.2022; 60(4): 261. CrossRef

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Malaria Endemicity in the Rural Communities of Ebonyi State, Nigeria: David Ekene Nwele, Ikechukwu Oliver Onyali, Milliam Okwudili Iwueze, Michael Okpara Elom, Ogbonna Elom Sabastian Uguru; Korean J Parasitol 2022;60(3):173-179.
Published online June 30, 2022; DOI: https://doi.org/10.3347/kjp.2022.60.3.173

Abstract
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Malaria remains a global health threat. Approximately 97% of the population is at risk in sub-Saharan countries, particularly Nigeria. This study compared the performance of 2 diagnostic methods in assessing malaria endemicity in the rural communities of Ebonyi State, Nigeria. A total of 1,140 study participants were screened for malaria parasite using Rapid Diagnostic Test kits (RDT) in the field, while thick and thin films for microscopy were examined in the laboratory. Our result showed that malaria prevalence was 56.8 by RDT and 38.6% by microscopic test. Age group under 10 years had the highest prevalence of 28.9% (RDT) and 23.6% (microscopy), respectively. The highest prevalence of 19.5% by RDT was recorded in Onicha Local Government Area, while the highest prevalence of 13.4% with microscopy was recorded in Ezza North Local Government Area. The sensitivity and specificity of microscopic examination were both 100%, while those of RDT were 95.5% and 75.9%, respectively.

Citations

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Subclinical Plasmodium spp. Infections in a Community Setting in Bangui, Central African Republic
Romaric Nzoumbou-Boko, Mireille Cornelia Ingrid Denissio Morissi Nalingbo, Brice Martial Yambiyo, Roger Detol, Ermeland Moussa, Didita Nalinga, Lydie Joella-Venus de la Grace Namsenei-Dankpea, Alexandre Manirakiza, Lawrence Ayong, Yap Boum
Research and Reports in Tropical Medicine.2025; Volume 16: 1. CrossRef
Explainable AI for enhanced accuracy in malaria diagnosis using ensemble machine learning models
Olushina Olawale Awe, Peter Njoroge Mwangi, Samuel Kotva Goudoungou, Ruth Victoria Esho, Olanrewaju Samuel Oyejide
BMC Medical Informatics and Decision Making.2025;[Epub] CrossRef
Ectoparasite species diversity and prevalence in pigs (Sus scrofa domesticus) within delta central senatorial district, Delta State, Nigeria

International Journal of Biosciences (IJB).2025; : 320. CrossRef
Analysis of fractional-order model for the transmission dynamics of malaria via Caputo–Fabrizio and Atangana–Baleanu operators
Benedict Celestine Agbata, Raimonda Dervishi, Mehmet Gümüş, Aseel Smerat, Godwin Christopher Ezike Mbah
Scientific Reports.2025;[Epub] CrossRef
Estimated distribution of malaria cases among children in sub-Saharan Africa by specified age categories using data from the Global Burden of Diseases 2019
Olorunfemi A. Oshagbemi, Pedro Lopez-Romero, Cornelis Winnips, Katalin R. Csermak, Guoqin Su, Elodie Aubrun
Malaria Journal.2023;[Epub] CrossRef

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Mini Review

Infection Characteristics of Clonorchis sinensis Metacercariae in Fish from Republic of Korea: Woon-Mok Sohn; Korean J Parasitol 2022;60(2):79-96.
Published online April 20, 2022; DOI: https://doi.org/10.3347/kjp.2022.60.2.79

The infection nature of Clonorchis sinensis metacercariae (CsMc) in freshwater fish hosts is closely related to the transmission of human clonorchiasis. This article reviewed the infection characteristics of CsMc in freshwater fish in the Republic of Korea (Korea). The status of CsMc infection was examined in a total of 17,792 cyprinid fish of 49 species in 9 water systems, which included Hantan-/Imjin-gang, Han-gang, Geum-gang, Mangyeong-gang, Yeongsan-gang, Tamjin-gang, Seomjin-gang, Nakdong-gang, and streams in the east coastal areas from 2010 to 2020. The infection status of CsMc was examined according to cyprinid fish species and water systems, after which analyzed by endemicity and susceptibility index. The high endemicity was shown in the cyprinid fish from 3 regions (6.1%) in the upper reaches of Nakdong-gang, such as Banbyeon-cheon (stream), Yongjeon-cheon, and Wi-cheon. The moderate levels were observed in fishes from 8 regions (16.3%), and low endemicity was shown in fishes from 20 regions (40.8%). No CsMc were detected in fish from 18 regions (36.7%). The susceptibility of CsMc in index fish, Puntungia herzi, was found to be a reliable index without examination of other fish species. CsMc infection rates were closely related to subfamily groups in the cyprinid fish hosts in a highly endemic area. In Korea, a total of 58 fish species in 10 families has been listed as the second intermediate hosts for C. sinensis. This review provides several novel features of CsMc infection and clarifies the species of second intermediate freshwater fish host in Korea.

Citations

Citations to this article as recorded by

Clonorchis sinensis and Cholangiocarcinoma
Eun-Min Kim, Sung-Tae Hong
Journal of Korean Medical Science.2025;[Epub] CrossRef
Multiparasitism in Spain in a Korean Visiting Friends and Relatives: Case Report and Review of Imported Cases of Clonorchis sinensis in Europe
Paola Cociancic, Jacklyn Comas, J. Guillermo Esteban
Clinical Case Reports.2025;[Epub] CrossRef
Clonorchiasis and opisthorchiasis: epidemiology, transmission, clinical features, morbidity, diagnosis, treatment, and control
Men-Bao Qian, Jennifer Keiser, Jürg Utzinger, Xiao-Nong Zhou, Graeme N. Forrest
Clinical Microbiology Reviews.2024;[Epub] CrossRef
Infection characteristics of Metagonimus species (Digenea: Heterophyidae) metacercariae in fish from major rivers of Korea
Woon-Mok Sohn
Parasites, Hosts and Diseases.2024; 62(1): 1. CrossRef
Current status of Clonorchis sinensis and clonorchiasis in Korea: epidemiological perspectives integrating the data from human and intermediate hosts
Won Gi Yoo, Woon-Mok Sohn, Byoung-Kuk Na
Parasitology.2022; 149(10): 1296. CrossRef

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Brief Communication

Awareness and Opinions of Inhabitants on Vivax Malaria in Two Endemic Areas, Gyeonggi-do, Korea: Young Yil Bahk, Shin-Hyeong Cho, Byoung-Kuk Na, Sung Jong Hong, Sung-Keun Lee, Tong-Soo Kim; Korean J Parasitol 2021;59(5):513-518.
Published online October 22, 2021; DOI: https://doi.org/10.3347/kjp.2021.59.5.513

Abstract
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The incidence of vivax malaria in Korea was reduced to a low plateau. For successful elimination of vivax malaria, socio-behavioral changes in the communities are essential. This study aimed to figure out awareness of the inhabitants on the vivax malaria endemicity. The 407 participants including vivax malaria patients and uninfected inhabitants in Gimpo- and Paju-si, Gyeonggi-do, known as high-risk areas in Korea. We used a community-based study design and non-probability sampling method using primary data. Except for the perception about the public health facilities’ capability to cope with anti-malaria programs, the 2 groups of participants shared the same level of awareness about public promotional and educational measures and opinions for malaria elimination from the community. Thus, our future goals for malaria prevention and elimination are to develop more active and well-organized community-based education and evaluation programs collaborating with the community healthcare authorities and local governments.

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Original Articles

Surveillance on the Vivax Malaria in Endemic Areas in the Republic of Korea Based on Molecular and Serological Analyses: Seong-Kyun Lee, Fengyue Hu, Egy Rahman Firdaus, Ji-Hoon Park, Jin-Hee Han, Sang-Eun Lee, Hyun-Il Shin, Shin Hyeong Cho, Won Sun Park, Feng Lu, Eun-Taek Han; Korean J Parasitol 2020;58(6):609-617.
Published online December 29, 2020; DOI: https://doi.org/10.3347/kjp.2020.58.6.609

Abstract
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Plasmodium vivax reemerged in 1993. It has been sustained for more than 25 years and become one of the important indigenous parasitic diseases in northern and western parts of the Republic of Korea near the demilitarized zone. In particular, relapse is a significant concern for the control of malaria, as short- and long-term incubation periods vary among those infected in Korea. In this study, the prevalence of asymptomatic carriers was examined among residents of high endemic areas of vivax malaria during nonseasonal transmission of mosquitoes. Blood samples from 3 endemic regions in northwestern Korea were evaluated by microscopic examination, rapid diagnostic testing, and nested PCR to identify asymptomatic patients carrying malaria parasites in the community. However, no positive malaria case among residents of endemic areas was detected. Additionally, serological analysis was carried out to measure antibodies against 3 antigenic recombinant proteins of P. vivax, merozoite surface protein 1-19, circumsporozoite surface protein-VK210, and liver-stage antigen (PvLSA-N), by the protein array method. Interestingly, seropositivity of sera between previous exposure and samples without exposure to malaria was significantly higher using the PvLSA-N antigen than the other antigens, suggesting that PvLSA-N can be used as a serological marker to analyze the degree of exposure for malaria transmission in endemic areas. This indicates a very low asymptomatic carrier prevalence during the nonmalaria season in the endemic areas of Korea.

Citations

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A region-structured model for early warning of Plasmodium vivax malaria transmission risk in the Republic of Korea
Boyeon Kim, Jung Ho Kim, Jeehyun Lee, Joon-Sup Yeom
Journal of Infection and Public Health.2025; 18(3): 102665. CrossRef
Development of a Plasmodium vivax malaria model for evaluating the effects of control strategies on the malaria burden in Democratic People’s Republic of Korea
Hye Seong, Jiyeon Suh, Jun Yong Choi, Jeehyun Lee, Joon-Sup Yeom
Frontiers in Public Health.2024;[Epub] CrossRef
Using Serological Markers for the Surveillance of Plasmodium vivax Malaria: A Scoping Review
Lejla Kartal, Ivo Mueller, Rhea J. Longley
Pathogens.2023; 12(6): 791. CrossRef
Recent Spatial and Temporal Trends of Malaria in Korea
Yeong Hoon Kim, Hye-Jin Ahn, Dongjae Kim, Sung-Jong Hong, Tong-Soo Kim, Ho-Woo Nam
The Korean Journal of Parasitology.2021; 59(6): 585. CrossRef

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Survey on Intestinal Helminthic Infection Status of Students in Two Counties, Hadong-gun and Goseong-gun, Korea: Young Yil Bahk, Yun-Kyu Park, Byoung-Kuk Na, Woon-Mok Sohn, Sung-Jong Hong, Jong-Yil Chai, Tong-Soo Kim; Korean J Parasitol 2018;56(4):335-339.
Published online August 31, 2018; DOI: https://doi.org/10.3347/kjp.2018.56.4.335

Abstract
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This study was conducted to investigate the prevalence of intestinal parasites among students from Goseonggun, Gangwon-do and Hadong-gun, Gyeongsangnam-do as typical low and high endemic counties. From May to July 2017, a total of 2,033 fecal samples were collected at 27 elementary, 10 junior high, and 8 high schools from 2 counties and examined by the Kato-Katz technique for egg-positive surveys (Collection rate: 37.02% [2,033/5,492]). Of the participants examined, 13 (0.64%) were found to harbor eggs of 3 parasitic species, Trichuris trichiura, Clonorchis sinensis and Metagonimus yokogawai. Based on the regional distribution, the egg-positive rate in Goseong-gun was 0% (0/550) and that in Hadong-gun was 0.88% (13/1,483). The positive rates for C. sinensis, M. yokogawai, and T. trichiura in Hadonggun were 0.20% (3/1,483), 0.61% (9/1,483), and 0.07% (1/1,483), respectively. The present survey showed that the prevalence of parasitic infection among students is currently very low even in remote, previously endemic areas, and the present status of parasitic diseases can be summarized as some transmission of fish/food-borne trematodes. Thus, it is necessary to carefully, continuously monitor the trematode infection status, particularly of C. sinensis and M. yokogawai.

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The spatial-temporal risk profiling of Clonorchis sinensis infection over 50 years implies the effectiveness of control programs in South Korea: a geostatistical modeling study
Hai-Yan Xiao, Jong-Yil Chai, Yue-Yi Fang, Ying-Si Lai
The Lancet Regional Health - Western Pacific.2023; 33: 100697. CrossRef
Global prevalence of 4 neglected foodborne trematodes targeted for control by WHO: A scoping review to highlight the gaps
Rachel Tidman, Kaushi S. T. Kanankege, Mathieu Bangert, Bernadette Abela-Ridder, Paul R. Torgerson
PLOS Neglected Tropical Diseases.2023; 17(3): e0011073. CrossRef
Risk Factors for Clonorchis sinensis Infection in Residents of Binyang, Guangxi: A Cross-Sectional and Logistic Analysis Study
Meng Xu, Yanyan Jiang, Jianhai Yin, Shengkui Cao, Yujuan Shen, Jianping Cao
Frontiers in Public Health.2021;[Epub] CrossRef
Currently Available Monitoring and Surveillance Systems for Taenia spp., Echinococcus spp., Schistosoma spp., and Soil-Transmitted Helminths at the Control/Elimination Stage: A Systematic Review
Ganna Saelens, Sarah Gabriël
Pathogens.2020; 9(1): 47. CrossRef
Status of common parasitic diseases in Korea in 2019
Sun Huh
Journal of the Korean Medical Association.2019; 62(8): 437. CrossRef
Blood Pressure and the Risk of Death From Non-cardiovascular Diseases: A Population-based Cohort Study of Korean Adults
Jeoungbin Choi, Jieun Jang, Yoonsuk An, Sue K. Park
Journal of Preventive Medicine and Public Health.2018; 51(6): 298. CrossRef

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Allelic Diversity of MSP1 Gene in Plasmodium falciparum from Rural and Urban Areas of Gabon: Denise Patricia Mawili-Mboumba, No? Mbondoukwe, Elvire Adande, Marielle Karine Bouyou-Akotet; Korean J Parasitol 2015;53(4):413-419.
Published online August 25, 2015; DOI: https://doi.org/10.3347/kjp.2015.53.4.413

Abstract
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The present study determined and compared the genetic diversity of Plasmodium falciparum strains infecting children living in 2 areas from Gabon with different malaria endemicity. Blood samples were collected from febrile children from 2008 to 2009 in 2 health centres from rural (Oyem) and urban (Owendo) areas. Genetic diversity was determined in P. falciparum isolates by analyzing the merozoite surface protein-1 (msp1) gene polymorphism using nested-PCR. Overall, 168 children with mild falciparum malaria were included. K1, Ro33, and Mad20 alleles were found in 110 (65.5%), 94 (55.9%), and 35 (20.8%) isolates, respectively, without difference according to the site (P>0.05). Allelic families’ frequencies were comparable between children less than 5 years old from the 2 sites; while among the older children the proportions of Ro33 and Mad20 alleles were 1.7 to 2.0 fold higher at Oyem. Thirty-three different alleles were detected, 16 (48.5%) were common to both sites, and 10 out of the 17 specific alleles were found at Oyem. Furthermore, multiple infection carriers were frequent at Oyem (57.7% vs 42.2% at Owendo; P=0.04) where the complexity of infection was of 1.88 (±0.95) higher compared to that found at Owendo (1.55±0.75). Extended genetic diversity of P. falciparum strains infecting Gabonese symptomatic children and high multiplicity of infections were observed in rural area. Alleles common to the 2 sites were frequent; the site-specific alleles predominated in the rural area. Such distribution of the alleles should be taken into accounts when designing MSP1 or MSP2 malaria vaccine.

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Plasmodium falciparum genetic diversity and multiplicity of infection based on msp-1, msp-2, glurp and microsatellite genetic markers in sub-Saharan Africa: a systematic review and meta-analysis
Alex Mwesigwa, Moses Ocan, Benson Musinguzi, Rachel Wangi Nante, Joaniter I. Nankabirwa, Steven M. Kiwuwa, Alison Annet Kinengyere, Barbara Castelnuovo, Charles Karamagi, Ekwaro A. Obuku, Samuel L. Nsobya, Sam M. Mbulaiteye, Pauline Byakika-Kibwika
Malaria Journal.2024;[Epub] CrossRef
The diversity of Plasmodium falciparum isolates from asymptomatic and symptomatic school-age children in Kinshasa Province, Democratic Republic of Congo
Shirley V. Simpson, Sabin S. Nundu, Hiroaki Arima, Osamu Kaneko, Toshihiro Mita, Richard Culleton, Taro Yamamoto
Malaria Journal.2023;[Epub] CrossRef
Comparative study of Plasmodium falciparum msp-1 and msp-2 Genetic Diversity in Isolates from Rural and Urban Areas in the South of Brazzaville, Republic of Congo
Marcel Tapsou Baina, Abel Lissom, Naura Veil Assioro Doulamo, Jean Claude Djontu, Dieu Merci Umuhoza, Jacques Dollon Mbama-Ntabi, Steve Diafouka-Kietela, Jolivet Mayela, Georges Missontsa, Charles Wondji, Ayola Akim Adegnika, Etienne Nguimbi, Steffen Borr
Pathogens.2023; 12(5): 742. CrossRef
Dynamics of Plasmodium falciparum genetic diversity among asymptomatic and symptomatic children in three epidemiological areas in Cote d’Ivoire
Akpa Paterne Gnagne, Abibatou Konate, Akoua Valérie Bedia-Tanoh, Mireille Amiah-Droh, Hervé Ignace Eby Menan, Assanvo Simon-Pierre N’Guetta, William Yavo
Pathogens and Global Health.2019; 113(3): 133. CrossRef
High-Complexity Plasmodium falciparum Infections, North Central Nigeria, 2015–2018
Bitrus Yakubu, Ishaya Yohanna Longdet, Horsfall Jen Tony, Dinchi Tyem Davou, Emmanuel Obishakin
Emerging Infectious Diseases.2019; 25(7): 1330. CrossRef
DNA recovery from archived RDTs for genetic characterization of Plasmodium falciparum in a routine setting in Lambaréné, Gabon
The Trong Nguyen, Brice Nzigou Mombo, Albert Lalremruata, Erik Koehne, Rella Zoleko Manego, Lia Betty Dimessa Mbadinga, Ayola Akim Adegnika, Selidji Todagbe Agnandji, Bertrand Lell, Peter Gottfried Kremsner, Thirumalaisamy P Velavan, Michael Ramharter, Be
Malaria Journal.2019;[Epub] CrossRef
Spatial and temporal distribution of Pfmsp1 and Pfmsp2 alleles and genetic profile change of Plasmodium falciparum populations in Gabon
J.M. Ndong Ngomo, N.P. M’Bondoukwe, W. Yavo, L.C. Bongho Mavoungou, M.K. Bouyou-Akotet, D.P. Mawili-Mboumba
Acta Tropica.2018; 178: 27. CrossRef
Extensive diversity in the allelic frequency of Plasmodium falciparum merozoite surface proteins and glutamate-rich protein in rural and urban settings of southwestern Nigeria
Roland I. Funwei, Bolaji N. Thomas, Catherine O. Falade, Olusola Ojurongbe
Malaria Journal.2018;[Epub] CrossRef
Plasmodium falciparum merozoite protein-1 genetic diversity and multiplicity of infection in isolates from Congolese children consulting in a pediatric hospital in Brazzaville
Nerly Shirère Gampio Gueye, Francine Ntoumi, Christevy Vouvoungui, Simon Charles Kobawila, Michael NKombo, Alain M. Mouanga, Julia Deibert, Felix Koukouikila-Koussounda
Acta Tropica.2018; 183: 78. CrossRef
Genetic Polymorphism ofmsp1 andmsp2 inPlasmodium falciparumIsolates from Côte d’Ivoire versus Gabon
William Yavo, Abibatou Konaté, Denise Patricia Mawili-Mboumba, Fulgence Kondo Kassi, Marie L. Tshibola Mbuyi, Etienne Kpongbo Angora, Eby I. Hervé Menan, Marielle K. Bouyou-Akotet
Journal of Parasitology Research.2016; 2016: 1. CrossRef

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Brief Communication

Decrease of Metagonimus yokogawai Endemicity along the Tamjin River Basin: Jin-Ju Lee, Hyo-Jin Kim, Min-Jae Kim, Jo Woon Yi Lee, Bong-Kwang Jung, Ji-Youn Lee, Eun-Hee Shin, Jae-Lip Kim, Jong-Yil Chai; Korean J Parasitol 2008;46(4):289-291.
Published online December 20, 2008; DOI: https://doi.org/10.3347/kjp.2008.46.4.289

Abstract
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The Tamjin River which flows from Jangheung-gun via Gangjin-gun to the South Sea was reported to be a highly endemic area of Metagonimus yokogawai infection in 1977 and 1985. However, there were no recent studies demonstrating how much change occurred in the endemicity, in terms of prevalence and worm burden, of metagonimiasis in this river basin. Thus, a small-scale epidemiological survey was carried out on some residents along the Tamjin River basin in order to determine the current status of M. yokogawai infection. A total of 48 fecal samples were collected and examined by the Kato-Katz thick smear and formalin-ether sedimentation techniques. The egg positive rate of all helminths was 50.0%, and that of M. yokogawai was 37.5%, followed by C. sinensis 22.9% and G. seoi 4.2%. To obtain the adult flukes of M. yokogawai, 6 egg positive cases were treated with praziquantel 10 mg/kg in a single dose and purged with magnesium sulfate. A total of 5,225 adult flukes (average 871 specimens per person) of M. yokogawai were collected from their diarrheic stools. Compared with the data reported in 1977 and 1985, the individual worm burdens appeared to have decreased remarkably, although the prevalence did not decrease at all. It is suggested that the endemicity of M. yokogawai infection along the Tamjin River has been reduced. To confirm this suggestion, the status of infection in snail and fish intermediate hosts should be investigated.

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Original Article

A new endemic focus of Heterophyes nocens and other heterophyid infections in a coastal area of Gangjin-gun, Jeollanam-do: Jae-Hwan Park, Jae-Lip Kim, Eun-Hee Shin, Sang-Mee Guk, Yun-Kyu Park, Jong-Yil Chai; Korean J Parasitol 2007;45(1):33-38.
Published online March 20, 2007; DOI: https://doi.org/10.3347/kjp.2007.45.1.33

Abstract
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To know the prevalence of heterophyid trematodes among inhabitants of a southern coastal village, i.e., Sacho-ri, Gangjin-gun, Jeollanam-do (Province), 82 stool samples were examined on helminth eggs and protozoan cysts using Kato-Katz and formalin-ether sedimentation techniques. Total 33 people (40.2%) were positive for trematodes (Heterophyes nocens; 15 people, Pygidiopsis summa; 3, Metagonimus sp.; 4, Clonorchis sinensis; 7, Gymnophalloides seoi; 6) and/or protozoa (Entamoeba coli; 3). Among intestinal trematode egg positive cases, 17 were treated with praziquantel and their whole diarrheic stools were collected after purgation. Adult flukes of H. nocens (number of specimens = 1,294), P. summa (386), Stellantchasmus falcatus (5), Stictodora lari (4), and Heterophyopsis continua (1) were collected using a stereomicroscope. To know the source of human H. nocens infections in this village, metacercarial infections in mullets (10) were examined and most H. nocens metacercariae (101/105, 96.2%) were found in the trunk portion. From above results, the surveyed coastal village has been newly known as an endemic focus of human H. nocens infection and consuming raw mullets was the presumable source of human heterophyid infections.

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