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"eosinophilia"

Original Article

Prevalence of Toxocariasis and Its Risk Factors in Patients with Eosinophilia in Korea
Hyun Beom Song, Deokho Lee, Yan Jin, Jinwoo Kang, Shin-Hyeong Cho, Min Sun Park, Jin-Ho Park, Woo-Jung Song, Hye-Ryun Kang, Sang Hyub Lee, Sung-Tae Hong, Min-Ho Choi
Korean J Parasitol 2020;58(4):413-419.
Published online August 26, 2020
DOI: https://doi.org/10.3347/kjp.2020.58.4.413
Eosinophilia occurs commonly in many diseases including allergic diseases and helminthic infections. Toxocariasis has been suggested as one cause of eosinophilia. The present study was undertaken to examine the prevalence of toxocariasis in patients with eosinophilia and to identify the risk factors for toxocariasis. This prospective cohort study recruited a total of 81 patients with eosinophilia (34 males and 47 females) who visited the outpatient clinic at Seoul National University Hospital from January 2017 to February 2018 and agreed to participate in this study. The prevalence of toxocariasis was examined by T. canis-specific ELISA, and the various risk factors for toxocariasis were evaluated by a questionnaire survey. Among 81 patients with eosinophilia, 18 were positive for anti-T. canis antibodies (22.2%); 88.9% were male (16/18) and 11.1% were female (2/18). Multivariate statistical analysis revealed that males (OR 21.876, 95% CI: 1.667-287.144) with a history of consuming the raw meat or livers of animals (OR 5.899, 95% CI: 1.004-34.669) and a heavy alcohol-drinking habit (OR 8.767, 95% CI: 1.018-75.497) were at higher risk of toxocariasis in patients with eosinophilia. Toxocariasis should be considered a potential cause of eosinophilia when the patient has a history of eating the raw meat or livers of animals in Korea. A single course of albendazole is recommended to reduce the migration of Toxocara larvae in serologically positive cases with eosinophilia.

Citations

Citations to this article as recorded by  Crossref logo
  • Evaluation of a Multiplex Bead Assay for Strongyloides stercoralis diagnosis using the recombinant antigen rSs-NIE-1
    Joelma Nascimento de Souza, Wéslei Almeida Costa Araújo, Márcia Cristina Aquino Teixeira, Neci Matos Soares
    Diagnostic Microbiology and Infectious Disease.2026; 114(2): 117108.     CrossRef
  • High toxocariasis seroprevalence in a tri-border indigenous community (Brazil, Paraguay and Argentina): A One Health perspective
    Isabella Braghin Ferreira, Roberto Teixeira de Souza Filho, Susana Angélica Zevallos Lescano, Rogério Giuffrida, Daniele Rodrigues, Suelen Teixeira de Faria Resende, Fabiano Borges Figueiredo, Louise Bach Kmetiuk, Andrea Pires dos Santos, Alexander Welker
    One Health.2025; 21: 101106.     CrossRef
  • Human toxocariasis
    Susana Lopez-Alamillo, Pravallika Padyala, Megan Carey, Megan M. Duffey, Jill E. Weatherhead, Louisa A. Messenger, Bachir Medrouh, Marcelo U. Ferreira
    Clinical Microbiology Reviews.2025;[Epub]     CrossRef
  • First Report on the Seroprevalence and Risk Factors Associated with Toxocara Infection in Blood Donors from Romania
    Ana Alexandra Ardelean, Rodica Lighezan, Sorin Ursoniu, Sergiu Adrian Sprintar, Daniela Adriana Oatis, Alin Gabriel Mihu, Maria Alina Lupu, Tudor Rareș Olariu
    Pathogens.2025; 14(9): 857.     CrossRef
  • TỶ LỆ VÀ YẾU TỐ LIÊN QUAN NHIỄM TOXOCARA CANIS TẠI PHÒNG KHÁM BỆNH VIỆN ĐẠI HỌC Y DƯỢC 1 THÀNH PHỐ HỒ CHÍ MINH
    Nguyễn Ngọc Phi Anh Nguyễn Ngọc Phi Anh, Trần Thị Kim Dung Trần Thị Kim Dung, Huỳnh Thị Thu Thảo Huỳnh Thị Thu Thảo
    Tạp Chí Khoa Học Trường Đại Học Quốc Tế Hồng Bàng.2024; : 213.     CrossRef
  • Toxocariasis: potential association with bronchial asthma, and pneumonia among pediatric children
    Wegdan M. Abd El Wahab, Mona I. Ali, Shimaa S. Ibrahim, Yasmen A. Mohamed, Doaa A. Hamdy
    Journal of Parasitic Diseases.2023; 47(1): 93.     CrossRef
  • One health approach to toxocariasis in quilombola communities of southern Brazil
    Vamilton Alvares Santarém, Giovanni Kalempa Panazzolo, Louise Bach Kmetiuk, Orlei José Domingues, Isabella Braghin Ferreira, Roberto Teixeira de Souza Filho, João Henrique Farinhas, Fernando Rodrigo Doline, Susana Angélica Zevallos Lescano, Leandro Menegu
    Parasites & Vectors.2023;[Epub]     CrossRef
  • Seroprevalence of toxocariasis among allergic patients in Kuwait and its association with eosinophilia
    Mohammad Al-Awadhi, Wafaa Jamal
    Parasite Epidemiology and Control.2022; 18: e00260.     CrossRef
  • Green vegetable juice as a potential source of human fascioliasis in Korea
    Sungim Choi, Sunghee Park, Sooji Hong, Hyejoo Shin, Bong-Kwang Jung, Min Jae Kim
    One Health.2022; 15: 100441.     CrossRef
  • Serosurvey of anti-Toxocara canis antibodies in people experiencing homelessness and shelter workers from São Paulo, Brazil
    Vamilton Alvares Santarém, Anahi Chechia do Couto, Susana Zevallos Lescano, William Henry Roldán, Ruana Renostro Delai, Rogério Giuffrida, Louise Bach Kmetiuk, Alexander Welker Biondo, Sriveny Dangoudoubiyam, Andrea Pires dos Santos
    Parasites & Vectors.2022;[Epub]     CrossRef
  • Seroprevalence of Toxocariasis Among Hypereosinophilic Children: A Single Center Study, Tehran, Iran
    Meysam Sharifdini, Mehdi Zarean, Mehrzad Sadredinamin, Mitra Zare- Bavani, Sarah Sharifi-yazdi, Bahram Nikmanesh
    Archives of Pediatric Infectious Diseases.2022;[Epub]     CrossRef
  • The Role of Nile Tilapia (Oreochromis niloticus) in the Life Cycle of Toxocara spp.
    Everton André de Oliveira, Yslla Fernanda Fitz Balo Merigueti, Isabella Braghin Ferreira, Isabele Santos Garcia, Alini Soriano Pereira, Rosemeire de Souza Santos, Louise Bach Kmetiuk, Andrea Pires dos Santos, Alexander Welker Biondo, Rogerio Giuffrida, Va
    Frontiers in Veterinary Science.2021;[Epub]     CrossRef
  • 7,306 View
  • 185 Download
  • 11 Web of Science
  • Crossref

Case Report

Pulmonary Toxocariasis Mimicking Invasive Aspergillosis in a Patient with Ulcerative Colitis
Eun Jin Park, Joon Young Song, Min Ju Choi, Ji Ho Jeon, Jah-yeon Choi, Tae Un Yang, Kyung Wook Hong, Ji Yun Noh, Hee Jin Cheong, Woo Joo Kim
Korean J Parasitol 2014;52(4):425-428.
Published online August 29, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.4.425

A 45-year-old-male who had underlying ulcerative colitis and presented with fever and dry cough. Initially, the patient was considered to have invasive aspergillosis due to a positive galactomannan assay. He was treated with amphotericin B followed by voriconazole. Nevertheless, the patient deteriorated clinically and radiographically. The lung biopsy revealed eosinophilic pneumonia, and ELISA for Toxocara antigen was positive, leading to a diagnosis of pulmonary toxocariasis. After a 10-day treatment course with albendazole and adjunctive steroids, the patient recovered completely without any sequelae. Pulmonary toxocariasis may be considered in patients with subacute or chronic pneumonia unresponsive to antibiotic agents, particularly in cases with eosinophilia.

  • 11,705 View
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Brief Communication

A Seroepidemiological Survey of Toxocariasis among Eosinophilia Patients in Chungcheongnam-do
Min Seo, Sung Chul Yoon
Korean J Parasitol 2012;50(3):249-251.
Published online August 13, 2012
DOI: https://doi.org/10.3347/kjp.2012.50.3.249

There have been several reports on the relationship between toxocariasis and eosinophilia, but all have been limited to the areas of Seoul or Gangwon-do. In the present study, we investigated the seroprevalence of toxocariasis among eosinophilia patients in Chungcheongnam-do, the central district of Korea. Among the 101 patients tested, 51 (50.5%) were identified as positive by Toxocara ELISA, and 46 (45.5%) were confidently diagnosed with toxocariasis because of absence of any other cause of eosinophilia. Whereas 22 of 42 seropositive patients (52.3%) had a recent history of consuming raw livers, especially the cow liver, only 1 of 25 seronegative patients (4%) had done so (P<0.01). From these results, we could confirm that toxocariasis is related to eosinophilia, and infer that ingestion of raw cow liver plays a vital role in the transmission of toxocariasis in Chungcheongnam-do.

Citations

Citations to this article as recorded by  Crossref logo
  • Seroprevalence of Toxocara spp. infection and its associated factors among children in Vietnam: A cross-sectional study
    Giao Huynh, Dung Quoc Phan, Tien Minh Tran, Thai Duy Nguyen, Hau Viet Nguyen, Han Thi Ngoc Nguyen, Ly Trieu Vo
    Medicine.2025; 104(47): e46235.     CrossRef
  • Toxocariasis and Strongyloidiasis as Triggering Factors for Wells’ Syndrome
    Hendra Gunawan, Zulfan Zulfan
    Clinical, Cosmetic and Investigational Dermatology.2024; Volume 17: 1687.     CrossRef
  • Evidence of helminthic infestation and efficacy of anthelminthic treatment in children investigated for eosinophilia
    Predrag Rodic, Marija Cazic, Dejan Skoric, Jelena Lazic, Goran Milosevic, Srdja Jankovic, Nada Krstovski
    Vojnosanitetski pregled.2024; 81(9): 555.     CrossRef
  • Dog and Cat Contact as Risk Factor for Human Toxocariasis: Systematic Review and Meta-Analysis
    Yslla Fernanda Fitz Balo Merigueti, Rogerio Giuffrida, Rodrigo Costa da Silva, Louise Bach Kmetiuk, Andrea Pires Dos Santos, Alexander Welker Biondo, Vamilton Alvares Santarém
    Frontiers in Public Health.2022;[Epub]     CrossRef
  • Seroprevalence of Toxocariasis Among Hypereosinophilic Children: A Single Center Study, Tehran, Iran
    Meysam Sharifdini, Mehdi Zarean, Mehrzad Sadredinamin, Mitra Zare- Bavani, Sarah Sharifi-yazdi, Bahram Nikmanesh
    Archives of Pediatric Infectious Diseases.2022;[Epub]     CrossRef
  • Ocular Toxocariasis: Beyond Typical Patterns through the New Imaging Technologies
    I Hernanz, A Moll-Udina, Belles V. Llorenç, Civera A. Adan
    Ocular Immunology and Inflammation.2021; 29(7-8): 1252.     CrossRef
  • Keys to Unlock the Enigma of Ocular Toxocariasis: A Systematic Review and Meta-analysis
    Milad Badri, Aida Vafae Eslahi, Meysam Olfatifar, Sahar Dalvand, Elham Houshmand, Amir Abdoli, Hamidreza Majidiani, Ali Eslami, Mohammad Zibaei, Morteza Ghanbari Johkool, Ali Taghipour, Sima Hashemipour
    Ocular Immunology and Inflammation.2021; 29(7-8): 1265.     CrossRef
  • Prevalence of Toxocariasis and Its Risk Factors in Patients with Eosinophilia in Korea
    Hyun Beom Song, Deokho Lee, Yan Jin, Jinwoo Kang, Shin-Hyeong Cho, Min Sun Park, Jin-Ho Park, Woo-Jung Song, Hye-Ryun Kang, Sang Hyub Lee, Sung-Tae Hong, Min-Ho Choi
    The Korean Journal of Parasitology.2020; 58(4): 413.     CrossRef
  • Latent and AsymptomaticToxocaraInfection among Young Population in Northwest Iran: The Necessity of Informing People as a Potential Health Risk
    Tina Momeni, Mahmoud Mahami-Oskouei, Esmaeil Fallah, Abdolrasoul Safaiyan, Leyla Mahami-Oskouei
    Scientifica.2016; 2016: 1.     CrossRef
  • Evaluating correlation between serum liver enzymes and toxocariasis: a case control study
    Hosein Miladi, Mojtaba Didehdar, Reza Hajihossein, Fatemeh Rafiei, Zahra Eslamirad
    Asian Pacific Journal of Tropical Disease.2016; 6(6): 460.     CrossRef
  • Clinical characteristics and progression of liver abscess caused by toxocara
    Kyung Ho Ha, Jung Eun Song, Byung Seok Kim, Chang Hyeong Lee
    World Journal of Hepatology.2016; 8(18): 757.     CrossRef
  • Clinical Features of Ocular Toxocariasis in Adult Korean Patients
    Donghyun Jee, Kyu Seop Kim, Won Ki Lee, Wungjae Kim, Sohee Jeon
    Ocular Immunology and Inflammation.2015; : 1.     CrossRef
  • Cross-reactivity of Toxocariasis with Crude Antigen ofToxascaris leoninaLarvae by ELISA
    Yan Jin, Chenghua Shen, Sun Huh, Min-Ho Choi, Sung-Tae Hong
    Journal of Korean Medical Science.2015; 30(5): 549.     CrossRef
  • Seroepidemiology of Toxocariasis and Its Clinical Implications in Gwangju and Jeonnam-province, Korea
    Eun Jeong Won, Jin Kim, Myung-Geun Shin, Jong Hee Shin, Soon Pal Suh, Dong Wook Ryang
    Annals of Laboratory Medicine.2015; 35(4): 449.     CrossRef
  • The Prevalence of Toxocariasis and Diagnostic Value of Serologic Tests in Asymptomatic Korean Adults
    Jin-Young Lee, Moon Hee Yang, Jung-Hae Hwang, Mira Kang, Jae-Won Paeng, Sehyo Yune, Byung-Jae Lee, Dong-Chull Choi
    Allergy, Asthma & Immunology Research.2015; 7(5): 467.     CrossRef
  • Eosinophilic Meningitis Associated with Toxocariasis
    Jin Kyo Choi, Jin Woo Lee, Yong Hui Park, Seo Hyun Kim
    Journal of Neurocritical Care.2015; 8(2): 115.     CrossRef
  • Ocular toxocariasis: clinical features, diagnosis, treatment, and prevention
    Seong Joon Ahn, Na-Kyung Ryoo, Se Joon Woo
    Asia Pacific Allergy.2014; 4(3): 134.     CrossRef
  • Significance of Serum Antibody Test for Toxocariasis in Healthy Healthcare Examinees with Eosinophilia in Seoul and Gyeongsangnam-do, Korea
    Hong Seok Kim, Yan Jin, Min-Ho Choi, Jae-Hwan Kim, Young Ha Lee, Cheong Ha Yoon, Eui-Hyuk Hwang, Hun Kang, Sang-Yong Ahn, Gi Jin Kim, Sung-Tae Hong
    Journal of Korean Medical Science.2014; 29(12): 1618.     CrossRef
  • Chest CT findings of toxocariasis: Correlation with laboratory results
    J.H. Hur, I.J. Lee, J.-H. Kim, D.-G. Kim, H.J. Hwang, S.H. Koh, K. Lee
    Clinical Radiology.2014; 69(6): e285.     CrossRef
  • A Comparative Seroprevalence Study of Toxocariasis in Hypereosinophilic and Apparently Healthy Individuals
    Bahador Sarkari, Malihe Lari, Reza Shafiei, Seyed Mahmoud Sadjjadi
    Archives of Pediatric Infectious Diseases.2014;[Epub]     CrossRef
  • Anti-Toxocara spp. antibodies in an adult healthy population: serosurvey and risk factors in Southeast Brazil
    Elaine Cristina Negri, Vamilton Alvares Santarém, Guita Rubinsky-Elefant, Rogério Giuffrida
    Asian Pacific Journal of Tropical Biomedicine.2013; 3(3): 211.     CrossRef
  • Serodiagnosis of Toxocariasis by ELISA Using Crude Antigen of Toxocara canis Larvae
    Yan Jin, Chenghua Shen, Sun Huh, Woon-Mok Sohn, Min-Ho Choi, Sung-Tae Hong
    The Korean Journal of Parasitology.2013; 51(4): 433.     CrossRef
  • Chemotherapeutic drugs for common parasitic diseases in Korea
    Sun Huh
    Journal of the Korean Medical Association.2013; 56(6): 513.     CrossRef
  • 9,050 View
  • 88 Download
  • Crossref

Case Report

Three Cases of Paragonimiasis in a Family
Byeong Seok Sohn, Yun-Jeong Bae, You Sook Cho, Hee-Bom Moon, Tae-Bum Kim
Korean J Parasitol 2009;47(3):281-285.
Published online August 28, 2009
DOI: https://doi.org/10.3347/kjp.2009.47.3.281

Paragonimiasis typically results from the consumption of raw or improperly cooked crustacea, especially crabs and crayfish. Although previously endemic in Korea, the prevalence of this disease decreased in the early 1970s because of educational campaigns and fewer intermediate hosts as a result of ecological changes. Recently, we were presented with a family where all members were infected with Paragonimus after ingestion of Kejang (= drunken crab). The mother was hospitalized for general myalgia and weakness first, followed by the father, who was hospitalized for dyspnea 2 month later. After the parents were diagnosed with paragonimiasis, we recommended their daughter to visit our hospital for a checkup, because they all had eaten freshwater crabs soaked in soybean sauce. She complained of generalized myalgia, fever, and pleuritic pain, and was also diagnosed with paragonimiasis. Peripheral blood of the 3 patients revealed hypereosinophilia, and computed tomography (CT) scans of their chests showed pleural effusion. The results of antibody tests by ELISA were positive for paragonimiasis. We report here the case series of familial paragonimiasis in a modern urban city, rather than in a typical endemic area.

Citations

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  • A Cluster of Paragonimiasis with Delayed Diagnosis Due to Difficulty Distinguishing Symptoms from Post-COVID-19 Respiratory Symptoms: A Report of Five Cases
    Jun Sasaki, Masanobu Matsuoka, Takashi Kinoshita, Takayuki Horii, Shingo Tsuneyoshi, Daiki Murata, Reiko Takaki, Masaki Tominaga, Mio Tanaka, Haruhiko Maruyama, Tomotaka Kawayama, Tomoaki Hoshino
    Medicina.2023; 59(1): 137.     CrossRef
  • Analysis of COI and ITS2 regions of DNA obtained from Paragonimus westermani eggs in ancient coprolites on Joseon dynasty mummies
    Jong Ha Hong, Chang Seok Oh, Min Seo, Dong Hoon Shin
    Memórias do Instituto Oswaldo Cruz.2019;[Epub]     CrossRef
  • Paragonimus and paragonimiasis in Asia: An update
    Ayako Yoshida, Pham Ngoc Doanh, Haruhiko Maruyama
    Acta Tropica.2019; 199: 105074.     CrossRef
  • Inactivation of Paragonimus westermani metacercariae in soy sauce-marinated and frozen freshwater crabs
    Tae Im Kim, Se-Ra Oh, Fuhong Dai, Hyun-Jong Yang, Sang-Do Ha, Sung-Jong Hong
    Parasitology Research.2017; 116(3): 1003.     CrossRef
  • Paragonimiasis in Children in Southwest China
    Zongrong Gong, Ruixue Miao, Min Shu, Yu Zhu, Yang Wen, Qin Guo, Qiong Liao, Chaomin Wan
    Medicine.2017; 96(25): e7265.     CrossRef
  • Recent Incidence of Paragonimus westermani Metacercariae in Freshwater Crayfish, Cambaroides similis, from Two Enzootic Sites in Jeollanam-do, Korea
    Jin-Ho Song, Fuhong Dai, Xuelian Bai, Tae-Im Kim, Hyun-Jong Yang, Tong-Soo Kim, Shin-Hyung Cho, Sung-Jong Hong
    The Korean Journal of Parasitology.2017; 55(3): 347.     CrossRef
  • A Case of Ectopic Paragonimiasis in a 17th Century Korean Mummy
    D. H. Shin, Y.-S. Kim, D. S. Yoo, M. J. Kim, C. S. Oh, J. H. Hong, E. Lee, J. Y. Chai, M. Seo
    Journal of Parasitology.2017; 103(4): 399.     CrossRef
  • Clinical Update on Parasitic Diseases
    Min Seo
    Korean Journal of Medicine.2013; 85(5): 469.     CrossRef
  • Ectopic paragonimiasis from 400-year-old female mummy of Korea
    Dong Hoon Shin, Chang Seok Oh, Sang Jun Lee, Eun-Joo Lee, Se Gwon Yim, Myeung Ju Kim, Yi-Suk Kim, Soong Deok Lee, Yong Seok Lee, Hye Jung Lee, Min Seo
    Journal of Archaeological Science.2012; 39(4): 1103.     CrossRef
  • Consecutive extrapulmonary paragonimiasis involving liver and colon
    Chang Wook PARK, Woo Jin CHUNG, Young Lan KWON, Yong Jin KIM, Eun Soo KIM, Byung Kuk JANG, Kyung Sik PARK, Kwang Bum CHO, Jae Seok HWANG, Jung Hyuk KWON
    Journal of Digestive Diseases.2012; 13(3): 186.     CrossRef
  • Characterization of MicroRNAs in Paragonimus westermani by Solexa Deep Sequencing and Bioinformatics Analysis
    L. Ai, M.X. Chen, S.H. Chen, Y.N. Zhang, H. Li, Y.C. Cai, Y. Lu, L.G. Tian, X.N. Zhou, J.X. Chen
    Journal of Animal and Veterinary Advances.2012; 11(18): 3469.     CrossRef
  • Sensitive and rapid detection of Paragonimus westermani infection in humans and animals by loop-mediated isothermal amplification (LAMP)
    M. X. Chen, L. Ai, R. L. Zhang, J. J. Xia, K. Wang, S. H. Chen, Y. N. Zhang, M. J. Xu, X. Li, X. Q. Zhu, J. X. Chen
    Parasitology Research.2011; 108(5): 1193.     CrossRef
  • A Case of Pulmonary Paragonimiasis with Involvement of the Abdominal Muscle in a 9-Year-Old Girl
    Ah-Rum Cho, Hae-Ran Lee, Kwan-Sub Lee, Sang-Eun Lee, So-Yeon Lee
    The Korean Journal of Parasitology.2011; 49(4): 409.     CrossRef
  • Prevalence of Paragonimus and Angiostrongylus cantonensis Infections in Snails in Southeastern China
    Y.Z. Cheng, J. Hou, X.H. He, Z.K. Hong, L.S. Li, G.H. Lin, M.X. Chen, S.H. Chen
    Journal of Animal and Veterinary Advances.2011; 10(19): 2599.     CrossRef
  • A fluke occurrence of paramount significance
    D Gude, DP Bansal
    Journal of Postgraduate Medicine.2011; 57(3): 255.     CrossRef
  • 12,836 View
  • 102 Download
  • Crossref
Original Articles
Toxocariasis and Ingestion of Raw Cow Liver in Patients with Eosinophilia
Dongil Choi, Jae Hoon Lim, Dong-Chull Choi, Seung Woon Paik, Sun-Hee Kim, Sun Huh
Korean J Parasitol 2008;46(3):139-143.
Published online September 20, 2008
DOI: https://doi.org/10.3347/kjp.2008.46.3.139

Ingestion of raw animal liver has been suggested as a possible mode of infection of human toxocariasis. We evaluated the relationship between toxocariasis and the ingestion of raw meat in patients with eosinophilia of unknown etiology. The study population consisted of 120 patients presenting with peripheral blood eosinophilia (> 500 cells/?l or > 10% of the white blood cell count). They were divided into 2 groups: 104 seropositive patients based on a Toxocara excretory-secretory IgG ELISA and 16 seronegative patients. While 25.0% of seronegative patients had a recent history of eating raw cow liver, 87.5% of seropositive patients had this history. Multivariate statistical analysis showed that a recent history of eating raw cow liver was related to an increased risk of toxocariasis. Collectively, it is proposed that raw cow liver is a significant infection source of toxocariasis in the patients with eosinophilia of unknown etiology.

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  • Knowledge and risky behaviors of Kabul city butchers regarding Crimean-Congo hemorrhagic fever
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  • State-of-the-art of portable (bio)sensors based on smartphone, lateral flow and microfluidics systems in protozoan parasites monitoring: A review
    Raed H. Althomali, Ebraheem Abdu Musad Saleh, Jitendra Gupta, Aiman Mohammed Baqir Al-Dhalimy, Ahmed Hjazi, Beneen M. Hussien, Amran M. AL-Erjan, Abduladheem Turki Jalil, Rosario Mireya Romero-Parra, Luis Andres Barboza-Arenas
    Microchemical Journal.2023; 191: 108804.     CrossRef
  • Incidentally Detected Löffler’s Syndrome on Abdomen Magnetic Resonance Imaging: Case Report
    Yedaun Lee
    Investigative Magnetic Resonance Imaging.2023; 27(3): 158.     CrossRef
  • Who Let the Dogs Out? Unmasking the Neglected: A Semi-Systematic Review on the Enduring Impact of Toxocariasis, a Prevalent Zoonotic Infection
    Katrin Henke, Sotirios Ntovas, Eleni Xourgia, Aristomenis K. Exadaktylos, Jolanta Klukowska-Rötzler, Mairi Ziaka
    International Journal of Environmental Research and Public Health.2023; 20(21): 6972.     CrossRef
  • Therapy and Prevention for Human Toxocariasis
    Jean-François Magnaval, Emilie Bouhsira, Judith Fillaux
    Microorganisms.2022; 10(2): 241.     CrossRef
  • TOXOCARA CANİS VE VİSCERAL LARVA MİGRANS
    Selma KOCADEMİR, Kader YILDIZ
    Veteriner Farmakoloji ve Toksikoloji Derneği Bülteni.2022; 13(1): 47.     CrossRef
  • Dog and Cat Contact as Risk Factor for Human Toxocariasis: Systematic Review and Meta-Analysis
    Yslla Fernanda Fitz Balo Merigueti, Rogerio Giuffrida, Rodrigo Costa da Silva, Louise Bach Kmetiuk, Andrea Pires Dos Santos, Alexander Welker Biondo, Vamilton Alvares Santarém
    Frontiers in Public Health.2022;[Epub]     CrossRef
  • Isolation and Production of Human Monoclonal Antibody Proteins Against a Toxocara Canis Excretory-Secretory Recombinant Antigen
    Anizah Rahumatullah, Zamrina Baharudeen, Rahmah Noordin, Lim Theam Soon, Dinesh Balachandra, Nor Suhada Anuar, Fatin Hamimi Mustafa
    SSRN Electronic Journal .2022;[Epub]     CrossRef
  • Ocular Toxocariasis: Beyond Typical Patterns through the New Imaging Technologies
    I Hernanz, A Moll-Udina, Belles V. Llorenç, Civera A. Adan
    Ocular Immunology and Inflammation.2021; 29(7-8): 1252.     CrossRef
  • Role of cats in human toxocarosis
    Pablo David Jimenez Castro, Sarah GH Sapp
    Companion Animal.2021; 26(3): 6.     CrossRef
  • Infectious Causes of Eosinophilic Meningitis in Korean Patients: A Single-Institution Retrospective Chart Review from 2004 to 2018
    Sunghee Park, Jiwon Jung, Yong Pil Chong, Sung-Han Kim, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Min Jae Kim
    The Korean Journal of Parasitology.2021; 59(3): 227.     CrossRef
  • Electrochemical microfluidic immunosensor based on TES-AuNPs@Fe3O4 and CMK-8 for IgG anti-Toxocara canis determination
    Claudio F. Jofre, Matías Regiart, Martin A. Fernández-Baldo, Mauro Bertotti, Julio Raba, Germán A. Messina
    Analytica Chimica Acta.2020; 1096: 120.     CrossRef
  • Saccharomyces boulardii reduces the mean intensity of infection in mice caused by the consumption of liver contaminated by Toxocara canis
    Paula Dutra Cardoso, Débora Liliane Walcher, Priscila da Silva Cadore, Ana Carolina Beheregaray, Luis Augusto Xavier Cruz, Gabriel Baracy Klafke, Lourdes Helena Rodrigues Martins, João Luis Rheingantz Scaini, Luciana Farias da Costa de Avila, Fabricio Roc
    Parasitology Research.2020; 119(3): 1161.     CrossRef
  • Excretory/Secretory Metabolome of the Zoonotic Roundworm Parasite Toxocara canis
    Phurpa Wangchuk, Owen Lavers, David S. Wishart, Alex Loukas
    Biomolecules.2020; 10(8): 1157.     CrossRef
  • Prevalence of Toxocariasis and Its Risk Factors in Patients with Eosinophilia in Korea
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    The Korean Journal of Parasitology.2020; 58(4): 413.     CrossRef
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Seroprevalence of Toxocariasis among Healthy People with Eosinophilia
Yong-Hun Kim, Sun Huh, Young-Bae Chung
Korean J Parasitol 2008;46(1):29-32.
Published online March 20, 2008
DOI: https://doi.org/10.3347/kjp.2008.46.1.29

The aim of this study is to determine the Toxocara seropositive rate among healthy people with eosinophilia. A total of 97 people residing in Seoul who were healthy and whose blood eosinophilia was over 10%, as shown by regular health check-ups in 2004, were subjected to this study. Their sera were tested by immunoblotting and ELISA with the antigen of larval Toxocara canis excretory-secretory (ES) protein. Sixty-five sera were band-positive (67.0%). The seropositve control sera were positive to band sizes of 66 kDa, 56 kDa, 32 kDa, and 13 kDa. In ELISA, 63 sera (65.0%) were positive to T. canis ES protein. There was no significant correlation between the IgG ELISA titer and the level of eosinophilia (r = 0.156, P = 0.156). As there were insufficient data to determine whether there were cross-reactions with other helminthic infections, or whether atopy occurred, further studies are required to verify the cause of the seropositive reactions against T. canis ES antigen. Toxocariasis seropositivity is suggested to be the major cause of eosinophilia, since the Toxocara seroprevalence among Korean rural adults was shown to be approximately 5%.

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  • A Systematic Review and Meta-analysis of Toxocariasis in Iran: Is it Time to Take it Seriously?
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    Acta Parasitologica.2020; 65(3): 569.     CrossRef
  • Prevalence of Toxocariasis and Its Risk Factors in Patients with Eosinophilia in Korea
    Hyun Beom Song, Deokho Lee, Yan Jin, Jinwoo Kang, Shin-Hyeong Cho, Min Sun Park, Jin-Ho Park, Woo-Jung Song, Hye-Ryun Kang, Sang Hyub Lee, Sung-Tae Hong, Min-Ho Choi
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  • Status of common parasitic diseases in Korea in 2019
    Sun Huh
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  • First Report of Toxocara canis Seroprevalence in Military Personnel and Their Families with Eosinophilia Referred to a Military Hospital in Tehran, Iran, 2015 - 2016
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  • A Systematic Review of Toxocariasis: A Neglected But High-Prevalence Disease in Brazil
    Carlos Roberto Silveira Corrêa, Paula Mayara Matos Fialho
    The American Journal of Tropical Medicine and Hygiene.2016; 94(6): 1193.     CrossRef
  • Clinical characteristics and progression of liver abscess caused by toxocara
    Kyung Ho Ha, Jung Eun Song, Byung Seok Kim, Chang Hyeong Lee
    World Journal of Hepatology.2016; 8(18): 757.     CrossRef
  • SEROPOSITIVITY FOR ASCARIOSIS AND TOXOCARIOSIS AND CYTOKINE EXPRESSION AMONG THE INDIGENOUS PEOPLE IN THE VENEZUELAN DELTA REGION
    Zaida Araujo, Sietze Brandes, Elena Pinelli, María A. Bochichio, Andrea Palacios, Albina Wide, Bruno Rivas-Santiago, Juan Carlos Jiménez
    Revista do Instituto de Medicina Tropical de São Paulo.2015; 57(1): 47.     CrossRef
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    Hong Seok Kim, Yan Jin, Min-Ho Choi, Jae-Hwan Kim, Young Ha Lee, Cheong Ha Yoon, Eui-Hyuk Hwang, Hun Kang, Sang-Yong Ahn, Gi Jin Kim, Sung-Tae Hong
    Journal of Korean Medical Science.2014; 29(12): 1618.     CrossRef
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    Hee Kyung Yang, Se Joon Woo, Jeong-Min Hwang
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    Asia Pacific Allergy.2014; 4(3): 134.     CrossRef
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    San Seong, Daruchi Moon, Dong Kyu Lee, Hyung Eun Kim, Hyun Sup Oh, Soon Hyun Kim, Oh Woong Kwon, Yong Sung You
    The Korean Journal of Parasitology.2014; 52(5): 537.     CrossRef
  • A Comparative Seroprevalence Study of Toxocariasis in Hypereosinophilic and Apparently Healthy Individuals
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    Min Seo, Sung Chul Yoon
    The Korean Journal of Parasitology.2012; 50(3): 249.     CrossRef
  • Seroprevalence of toxocariasis in hypereosinophilic individuals in Ahwaz, south-western Iran
    S. Maraghi, A. Rafiei, R. Hajihossein, S. M. Sadjjadi
    Journal of Helminthology.2012; 86(2): 241.     CrossRef
  • Ultrastructural Localization of Toxocara canis Larval Antigen Reacted with a Seropositive Human Serum
    Soo-Ung Lee, Jae-Ran Yu, Sun Huh
    The Korean Journal of Parasitology.2009; 47(1): 65.     CrossRef
  • Frequency of eosinophilia and risk factors and their association with Toxocara infection in schoolchildren during a health survey in the north of Lima, Peru
    William H. Roldán, Yrma A. Espinoza, Arturo Atúncar, Emperatriz Ortega, América Martinez, Melissa Saravia
    Revista do Instituto de Medicina Tropical de São Paulo.2008; 50(5): 273.     CrossRef
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Partial cross-resistance between Strongyloides venezuelensis and Nippostrongylus brasiliensis in rats
Byeong-Kirl Baek, M. Khyrul Islam, Jin-Ho Kim, John-Wha Lee, Jin Hur
Korean J Parasitol 1999;37(2):101-107.
Published online June 30, 1999
DOI: https://doi.org/10.3347/kjp.1999.37.2.101

Rats were immunized through an initial infection with 1,000 filariform larvae (L3) of Nippostrongylus brasiliensis and after complete expulsion of worms they were challenged with 1,000 L3 of Strongyloides venezuelensis to investigate whether cross-resistance developed against a heterologous parasite. Nippostrongylus brasiliensis-immunized rats developed a partial cross-resistance against S. venezuelensis migrating larvae (MSL3) in the lungs and adult worms in the small intestine. The population of MSL3 in the lungs were significantly lower (P<0.05) in immunized rats (22.0 ± 7.4) compared with controls (105.0 ± 27.6). The populations of adult worms, egg output and fecundity were initially decreased but from day 14 post-challenge they did not show any significant difference between immunized and control rats. However, the length of worm in immunized rat was revealed as retardation. Peripheral blood eosinophilia was significantly decreased (P<0.05) on day 7 post-challenge and then gradually increased, which peaked on day 42 post-challenge when most of the worms were expelled. These results suggest that peripheral blood eosinophilia is strongly involved in the worm establishment and expulsion mechanisms.

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  • Systemic Immune Modulation by Gastrointestinal Nematodes
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    Mucosal Immunology.2022; 15(2): 257.     CrossRef
  • Nematode-Infected Mice Acquire Resistance to Subsequent Infection With Unrelated Nematode by Inducing Highly Responsive Group 2 Innate Lymphoid Cells in the Lung
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    Frontiers in Immunology.2018;[Epub]     CrossRef
  • Biotic and abiotic effects on the intestinal helminth community of the brown ratRattus norvegicusfrom Rio de Janeiro, Brazil
    R.O. Simões, J.L. Luque, R. Gentile, M.C.S. Rosa, S. Costa-Neto, A. Maldonado
    Journal of Helminthology.2016; 90(1): 21.     CrossRef
  • Migratory route of Strongyloides venezuelensis in Lewis rats: Comparison of histological analyses and PCR
    Nelson Mendes Marra, Fernanda Chiuso-Minicucci, Gabriel Capella Machado, Sofia Fernanda Gonçalves Zorzella-Pezavento, Thaís Graziela Donegá França, Larissa Lumi Watanabe Ishikawa, Alessandro F.T. Amarante, Alexandrina Sartori, Mônica R.V. Amarante
    Experimental Parasitology.2011; 127(2): 334.     CrossRef
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    Journal of Veterinary Medical Science.2003; 65(9): 971.     CrossRef
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