Parasites, Hosts and Diseases

"imported case"

Case Report

Imported human babesiosis in the Republic of Korea, 2019: two case reports: Hyun Jung Kim, Min Jae Kim, Hyun-Il Shin, Jung-Won Ju, Hee-Il Lee; Parasites Hosts Dis 2023;61(1):72-77.
Published online February 22, 2023; DOI: https://doi.org/10.3347/PHD.22168

Abstract
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Human babesiosis is a tick-borne disease induced by the genus Babesia and has been significantly reported in the Republic of Korea. This report shows the cases of 2 patients with human babesiosis who traveled to the USA in 2019. The 2 patients experienced fever and had travel histories to babesiosis-endemic regions. The diagnoses of both cases were verified by the identification of Babesia-infected red blood cells on blood smears. One patient was found to be infected with Babesia microti using polymerase chain reaction (PCR) for 18S rRNA, which discovered the phylogenetic link to the B. microti strain endemic in the USA. The 2 patients recovered from fever with subsequent hemoparasite clearance. Babesiosis could be diagnosed in anyone with histories of travel to babesiosis-endemic countries and tick bites. Furthermore, Babesia-specific PCR is required for determining geno-and phenotypic characteristics.

Citations

Citations to this article as recorded by

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Jong-Yil Chai
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PLOS One.2025; 20(8): e0327953. CrossRef
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Pathogens.2024; 13(12): 1094. CrossRef

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Brief Communication

Diagnosis and Molecular Analysis on Imported Plasmodium ovale curtisi and P. ovale wallikeri Malaria Cases from West and South Africa during 2013-2016: Hyun-Il Shin, Bora Ku, Yu Jung Kim, Tae Yun Kim, Shin-Hyeong Cho, Sang-Eun Lee; Korean J Parasitol 2020;58(1):61-65.
Published online February 29, 2020; DOI: https://doi.org/10.3347/kjp.2020.58.1.61

Abstract
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Majority of the imported malaria cases in Korea is attributed to Plasmodium falciparum and P. vivax infections, whereas P. malariae and P. ovale infections are very rare. Falciparum and ovale malaria are mostly imported from Africa, while most of the vivax malaria cases are imported from Southeast Asia. Here, we report 6 Korean imported ovale malaria cases (4 males and 2 females) who had visited in Africa during 2013-2016. These subjects were diagnosed with P. ovale based on microscopic findings, Plasmodium species-specific nested-PCR, and phylogenetic clade using 18S rRNA gene sequences. We identified 2 P. ovale subtypes, 1 P. ovale curtisi (classic type) and 5 P. ovale wallikeri (variant type). All patients were treated with chloroquine and primaquine, and no relapse or recrudescence was reported for 1 year after treatment. With increase of travelers to the countries where existing Plasmodium species, the risk of Plasmodium infection is also increasing. Molecular monitoring for imported malaria parasites should be rigorously and continuously performed to enable diagnosis and certification of Plasmodium spp.

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Case Report

Three clinical cases of cutaneous larva migrans: Tae-Heung Kim, Byeung-Song Lee, Woon-Mok Sohn; Korean J Parasitol 2006;44(2):145-149.
Published online June 20, 2006; DOI: https://doi.org/10.3347/kjp.2006.44.2.145

Abstract
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Three cases of cutaneous larva migrans (CLM) were diagnosed in a returnee from a trip to Thailand and in 2 domestic farmers during July and September, 2003. The linear and serpiginous skin lesions on the lower extremities were presented in all 3 cases. Routine laboratory findings were normal. In the imported case, a 650 × 30 ?m sized filariform nematode larva, presumably a species of hookworm, was detected in the lesion. All cases were treated with 400 mg albendazole once daily for 3-5 days, and their skin lesions gradually improved. In the present study, a causative agent of CLM was isolated for the first time in the Republic of Korea. Moreover, we speculate that CLM is prevalent in farmers who are in frequent contact with soil in the Republic of Korea.

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