Parasites, Hosts and Diseases

"worm growth"

Original Article

Growth and development of Gymnophalloides seoi in immunocompetent and immunosuppressed C3H/HeN mice: Jong-Yil Chai, Won-Jae Chung, Jina Kook, Min Seo, Yun-Kyu Park, Sang-Mee Guk, Min-Ho Choi, Soon-Hyung Lee; Korean J Parasitol 1999;37(1):21-26.
Published online March 31, 1999; DOI: https://doi.org/10.3347/kjp.1999.37.1.21

Abstract
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The growth and development of Gymnophalloides seoi were studied in C3H/HeN mice and effects of immunosuppression of the host on the worm development were observed. Two hundred metacercariae of G. seoi were orally administered to each mouse, and worms were recovered on days 1, 3, 5, 7, 14 and 21 post-infection (PI). The worm recovery rate was significantly higher in immunosuppressed (ImSP) mice than in immunocompetent (ImCT) mice except on days 1 and 3 PI. The worms attained sexual maturity by day 3 PI with eggs in the uterus, and worm dimensions and the number of uterine eggs continuously increased until day 14 PI in ImSP mice. Worms recovered from ImSP mice were significantly larger in size than those from ImCT mice on days 1 and 3 PI, and the number of uterine eggs was significantly larger in ImSP mice on days 5 and 7 PI. Genital organs such as the ovary, testes, and vitellaria, that were already developed in the metacercarial stage, grew a little in size until day 14 PI. The results show that the C3H/HeN mouse is, though not excellent, a suitable laboratory host for G. seoi.

Citations

Citations to this article as recorded by

Increased Intestinal Epithelial Cell Turnover and Intestinal Motility in Gymnophalloides seoi-Infected C57BL/6 Mice
Sang Hyub Lee, Bong-Kwang Jung, Jae-Hwan Park, Eun-Hee Shin, Jong-Yil Chai
The Korean Journal of Parasitology.2014; 52(3): 273. CrossRef
Foodborne Intestinal Flukes in Southeast Asia
Jong-Yil Chai, Eun-Hee Shin, Soon-Hyung Lee, Han-Jong Rim
The Korean Journal of Parasitology.2009; 47(Suppl): S69. CrossRef
Gymnophalloides seoi: a new human intestinal trematode
Jong-Yil Chai, Min-Ho Choi, Jae-Ran Yu, Soon-Hyung Lee
Trends in Parasitology.2003; 19(3): 109. CrossRef
Food-borne intestinal trematode infections in the Republic of Korea
Jong-Yil Chai, Soon-Hyung Lee
Parasitology International.2002; 51(2): 129. CrossRef
A review of Gymnophalloides seoi (Digenea: Gymnophallidae) and human infections in the Republic of Korea
Soon-Hyung Lee, Jong-Yil Chai
The Korean Journal of Parasitology.2001; 39(2): 85. CrossRef
Intestinal histopathology and in situ postures of Gymnophalloides seoi in experimentally infected mice
Jong-Yil Chai, Hong-Soon Lee, Sung-Jong Hong, Jae Hyung Yoo, Sang-Mee Guk, Min Seo, Min-Ho Choi, Soon-Hyung Lee
The Korean Journal of Parasitology.2001; 39(1): 31. CrossRef