Human infections by <i>Heterophyes heterophyes</i> and <i>H. dispar</i> imported from Saudi Arabia

, Chai, Jong Yil; , Seo, Byong Seol; , Lee, Soon Hyung; , Hong, Sung Jong; , Sohn, Woon Mok

doi:1986.24.1.82

Korean J Parasito > Volume 24(1):1986 > Article

Original Article


Korean J Parasitol. 1986 Jun;24(1):82-86. English. Published online Mar 20, 1994. http://dx.doi.org/10.3347/kjp.1986.24.1.82
Copyright © 1986 by The Korean Society for Parasitology


Human infections by Heterophyes heterophyes and H. dispar imported from Saudi Arabia
Jong Yil Chai,Byong Seol Seo,^*Soon Hyung Lee,Sung Jong Hong and Woon Mok Sohn
Department of Parasitology and Institute of Endemic Diseases, College of Medicine, Seoul National University, Seoul 110, Korea.


Abstract
Two human cases of Heterophyes heterophyes and H. dispar infections were proven by the recovery of their adult worms. The cases were 38-year and 40-year old Korean workers who had been in Saudi Arabia for 4-6 years and returned home in 1983 or 1984 with gastrointestinal troubles. In Saudi Arabia they had eaten raw brackish water fishes such as the mullet. After the treatment with 10 mg/kg praziquantel and purgation with magnesium salt, a total of 19 specimens of H.heterophyes and 140 of H. dispar were collected. It is of interest that the worms persisted in a patient although he had been back in Korea for 14 months. This is the first report on imported heterophyiasis in Korea. Human infection by H. dispar is the first record in the literature.

Figures

Figs. 1-7
Figs. 1-4.Heterophyes heterophyes collected from a Korean worker returned from Saudi Arabia. 1. A formalin-fixed specimen (from Case I) showing its genital sucker (GS) and other structures (Scale: 0.2mm). 2. Another specimen (acetocarmine-stained) showing the position and morphology of male and female genital organs (Scale: 0.2mm). 3. Magnification of its middle portion, where the ventral sucker (VS), genital sucker (GS) and total 73 chitinous rodlets are observed (Scale: 0.04mm). 4. Magnification of a portion of the uterine loop containing many eggs, 0.023~0.030mm long and 0.013~0.016mm wide (Scale: 0.04mm)

Figs 5-7.Heterophyes dispar collected form the same person. 5. A formalin-fixed specimen (from Case I) showing smaller body and smaller genital sucker (arrow) than H. heterophyes. Two intestinal ceca extend long but not as much posterior as in H. heterophyes (Scale: 0.2mm). 6. Another specimen (aceto-carmine-stained) showing a small genital sucker (arrow) and various genital organs (Scale: 0.2mm). 7. Magnification of its middle portion showing the ventral sucker (VS), genital sucker (GS) and total 31 rodlets (Scale: 0.04mm).

Tables


	Table 1 No. of heterophyid flukes collected from the present cases


	Table 2 Comparative measurements of H. heterophyes with those of other workers


	Table 3 Comparative measurements of H. dispar with those of other workers

References


1.	Ahn MH, et al. Yonsei Repts Trop Med 1982;13:23–29.

2.	Chai JY, et al. Seoul J Med 1985;26(2):197–200.

3.	Chai JY, Seo BS, Lee SH. Studies on intestinal trematodes in Korea XI. Two cases of human infection by Heterophyes heterophyes nocens. Korean J Parasitol 1984;22(1):37–42.

4.	Chi JG, Shong YK, Hong ST, Lee SH, Seo BS, Choe KW. An Imported Case Of Kala-Azar In Korea. Korean J Parasitol 1983;21(1):87–94.

5.	Collomb H, et al. Bull Soc Path Exot 1960;53:144–147.

6.	Fahmy MA, Selim MK. Studies on some trematode parasites of dogs in Egypt with special reference to the role played by fish in their transmission. Z Parasitenkd 1959;19(1):3–13.

7.	Gallais P, et al. Bull Soc Pth Exot 1956;48(6):830–832.

8.	Gomaa T. Pulmonary complications of Heterophyes infestation. J Egypt Med Assoc 1962;45:317–322.

9.	Kagei N, et al. Jap J Trop Med 1980;8(1):1–7.

*10.*	Kuntz RE, Chandler AC. Studies on Egyptian trematodes with special reference to the heterophyids of mammals. I. Adult flukes, with descriptions of Phagicola longicollis n. sp., Cynodiplostomum Namrui n. sp., and a stephanoprora from cats. J Parasitol 1956;42(4 Section 1):445–459.

*11.*	Lamy C, Duhamel C, Morel C, Valla A. [Letter: One case of intestinal distomatosis]. Nouv Presse Med 1976;5(15):1005–1006.

*12.*	Lee J, et al. Inje Med J 1986;7(1):107–114.

*13.*	Lee NH, et al. Eulji Med J 1981;4(2):143–151.

*14.*	Looss A. Centralbl Bakt Orig 1902;32:886–891.

*15.*	Min DY, et al. Yonsei Repts Trop Med 1982;13:36–40.

*16.*	Nakano T, et al. Geka No Ryoiki 1955;3:272–274.

*17.*	Park CS, et al. J Korean Med Ass 1985;28(11):1141–1146.

*18.*	Ransom BH. Proceed US Nat Museum 1920;57:527–573.

*19.*	Rousset JJ, Pasticier A. [2 cases of Heterophyides distomatosis. Epidemiologic and clinical aspects. Value of the concept of opsopathology]. Ann Parasitol Hum Comp 1972;47(4):465–474.

*20.*	Seo BS, et al. Seoul J Med 1981;22:228–235.

*21.*	Taraschewski H. Transmission experiments on the host specificity of Heterophyes species in 16 potential definitive hosts. Z Parasitenkd 1985;71(4):505–518.

*22.*	Wells WH, Randall BH. New hosts for trematodes of the genus Heterophyes in Egypt. J Parasitol 1956;42(3):287–292.

*23.*	Witenberg G. Ann Trop Med Parasit 1929;23:131–268.

*24.*	Yokogawa M, et al. Japanese J Parasit 1965;14(6):577–585.