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Antigen specificity of 36 and 31 kDa proteins of Spirometra erinacei plerocercoid in tissue invading nematodiasis
N Morakote,2 and Y Kong*2
1Department of Parasitology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50002, Thailand.
Received February 23, 1993; Accepted March 29, 1993.
Abstract
Diagnostic specificity of 36 and 31 kDa proteins of Spirometra erinacei plerocercoid (sparganum) was evaluated by micro-ELISA in tissue invading nematodiasis such as 25 gnathostomiasis, 33 angiostrongyliasis, 22 trichinellosis patients, and 20 normal control. All but one patient each in 3 nematodiases showed the antibody levels of negative range. The positively reacted patients were regarded as concomitant infections of sparganum because immunized or hyperinfected rabbit serum of the nematodes did not react crossly to the antigen.
Tables
Table 1 Mean (M) and standard deviation (S.D.) of abs. for sparganum-specific (IgG) antibody by micro-ELISA in gnathostomiais, angiostrongyliasis, trichinellosis and normal control against 36 and 31 kDa proteins of sparganum
Table 2 Antibody levels (ads.) in immunized or hyperinfected rabbit serum against each antigen
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