The encystation of Acanthamoeba leads to the development of metabolically inactive and dormant cysts from vegetative trophozoites under unfavorable conditions. These cysts are highly resistant to anti-Acanthamoeba drugs and biocides. Therefore, the inhibition of encystation would be more effective in treating Acanthamoeba infection. In our previous study, a sirtuin family protein—Acanthamoeba silent-information regulator 2-like protein (AcSir2)—was identified, and its expression was discovered to be critical for Acanthamoeba castellanii proliferation and encystation. In this study, to develop Acanthamoeba sirtuin inhibitors, we examine the effects of sirtinol, a sirtuin inhibitor, on trophozoite growth and encystation. Sirtinol inhibited A. castellanii trophozoites proliferation (IC50=61.24 μM). The encystation rate of cells treated with sirtinol significantly decreased to 39.8% (200 μM sirtinol) after 24 hr of incubation compared to controls. In AcSir2-overexpressing cells, the transcriptional level of cyst-specific cysteine protease (CSCP), an Acanthamoeba cysteine protease involved in the encysting process, was 11.6- and 88.6-fold higher at 48 and 72 hr after induction of encystation compared to control. However, sirtinol suppresses CSCP transcription, resulting that the undegraded organelles and large molecules remained in sirtinol-treated cells during encystation. These results indicated that sirtinol sufficiently inhibited trophozoite proliferation and encystation, and can be used to treat Acanthamoeba infections.
Citations
Citations to this article as recorded by
Pterostilbene: A natural neuroprotective stilbene with anti-Alzheimer's disease properties Songlan Gao, Honglei Zhang, Na Li, Lijuan Zhang, Zhe Zhu, Changlu Xu Journal of Pharmaceutical Analysis.2025; 15(4): 101043. CrossRef
Alzheimer’s Disease: A Review of Molecular Mechanisms and Therapeutic Implications by Targeting Sirtuins, Caspases, and GSK-3 Kalpana Pandya, Krishnashish Roul, Avanish Tripathi, Sateesh Belemkar, Anshuman Sinha, Meryem Erol, Devendra Kumar ACS Chemical Neuroscience.2025; 16(12): 2178. CrossRef
Human Conjunctival Transcriptome in Acanthamoeba Keratitis: An Exploratory Study Gerami D. Seitzman, Jeremy D. Keenan, Thomas M. Lietman, Kevin Ruder, Lina Zhong, Cindi Chen, YuHeng Liu, Danny Yu, Thomas Abraham, Armin Hinterwirth, Thuy Doan Cornea.2024; 43(10): 1272. CrossRef
Comparative cytotoxicity of Acanthamoeba castellanii-derived conditioned medium on human corneal epithelial and stromal cells Abdullah Alhazmi, Laura E. Sidney, Andy Hopkinson, Hany M. Elsheikha Acta Tropica.2024; 257: 107288. CrossRef
Biological characteristics and pathogenicity of Acanthamoeba Yuehua Wang, Linzhe Jiang, Yitong Zhao, Xiaohong Ju, Le Wang, Liang Jin, Ryan D. Fine, Mingguang Li Frontiers in Microbiology.2023;[Epub] CrossRef
Acanthamoeba keratitis (AK) is a rare infectious disease and accurate diagnosis has remained arduous as clinical manifestations of AK were similar to keratitis of viral, bacterial, or fungal origins. In this study, we described the production of a polyclonal peptide antibody against the adenylyl cyclase-associated protein (ACAP) of A. castellanii, and evaluated its differential diagnostic potential. Enzyme-linked immunosorbent assay revealed high titers of A. castellanii-specific IgG and IgA antibodies being present in low dilutions of immunized rabbit serum. Western blot analysis revealed that the ACAP antibody specifically interacted with A. castellanii, while not interacting with human corneal epithelial (HCE) cells and other causes of keratitis such as Fusarium solani, Pseudomonas aeruginosa, and Staphylococcus aureus. Immunocytochemistry (ICC) results confirmed the specific detection of trophozoites and cysts of A. castellanii co-cultured with HCE cells. The ACAP antibody also specifically interacted with the trophozoites and cysts of 5 other Acanthamoeba species. These results indicate that the ACAP antibody of A. castellanii can specifically detect multiple AK-causing members belonging to the genus Acanthamoeba and may be useful for differentially diagnosing Acanthamoeba infections.
Citations
Citations to this article as recorded by
The pathogenesis, risk factors, diagnosis and treatment of Acanthamoeba keratitis Mingliang Bao, Hai Bao, Shuqing Wang, Hongyan Zhou Frontiers in Medicine.2025;[Epub] CrossRef
A chorismate mutase-targeted, core-shell nanoassembly-activated SERS immunoassay platform for rapid non-invasive detection of Acanthamoeba infection Hyerin Lee, Min-Jeong Kim, Junkyu Chung, Wansun Kim, Hye-Jeong Jo, Tae Gi Kim, Jae-Ho Shin, Gi-Ja Lee, Fu-Shi Quan, Hyun-Hee Kong, Sang Woong Moon, Eun-Kyung Moon, Samjin Choi Nano Today.2024; 59: 102506. CrossRef
Evaluating the Diagnostic Potential of Chorismate Mutase Poly-Clonal Peptide Antibody for the Acanthamoeba Keratitis in an Animal Model Min-Jeong Kim, Hye-Jeong Jo, Hae-Jin Sohn, Ho-Joon Shin, Fu-Shi Quan, Hyun-Hee Kong, Eun-Kyung Moon Pathogens.2023; 12(4): 526. CrossRef
New Frontiers in Acanthamoeba Keratitis Diagnosis and Management Omar Shareef, Sana Shareef, Hajirah N. Saeed Biology.2023; 12(12): 1489. CrossRef
Detection of Acanthamoeba from Acanthamoeba Keratitis Mouse Model Using Acanthamoeba-Specific Antibodies Min-Jeong Kim, A-Jeong Ham, A-Young Park, Hae-Jin Sohn, Ho-Joon Shin, Fu-Shi Quan, Hyun-Hee Kong, Eun-Kyung Moon Microorganisms.2022; 10(9): 1711. CrossRef
Erythrocytes deficient in glucose-6-phosphate dehydrogenase (G6PD) is more susceptible to oxidative damage from free radical derived compounds. The hemolysis triggered by oxidative agents such as primaquine (PQ) is used for the radical treatment of hypnozoites of P. vivax. Testing of G6PD screening before malaria treatment is not a common practice in Thailand, which poses patients at risk of hemolysis. This retrospective study aimed to investigate the prevalence of G6PD in malaria patients who live in Southern Thailand. Eight hundred eighty-one malaria patients were collected for 8-year from 2012 to 2019, including 785 (89.1%) of P. vivax, 61 (6.9%) of P. falciparum, 27 (3.1%) of P. knowlesi, and 8 (0.9%) of mixed infections. The DiaPlexC genotyping kit (Asian type) and PCR-RFLP were employed to determine the G6PD variants. The result showed that 5 different types of G6PD variants were identified in 26 cases (2.9%); 12/26 (46.2%) had Mahidol (487G>A) and 11/26 (42.3%) had Viangchan (871G>A) variants, while the rest had Kaiping (1388G>A), Union (1360C>T), and Mediterranean (563C>T) variants. G6PD Songklanagarind (196T>A) variant was not found in the study. Our result did not show a significant difference in the malaria parasite densities in patients between G6PD-deficient and G6PD-normal groups. According to our findings, testing G6PD deficiency and monitoring the potential PQ toxicity in patients who receive PQ are highly recommended.
Citations
Citations to this article as recorded by
Prospective observational study to assess the feasibility and safety of appropriate Plasmodium vivax radical cure with tafenoquine or primaquine after quantitative G6PD testing during pilot implementation in Thailand Prayuth Sudathip, Nardlada Khantikul, Aungkana Saejeng, Stephan Duparc, Penny Grewal Daumerie, Caroline Lynch, Elodie Jambert, Saowanee Viboonsanti, Darin Areechokchai, Jerdsuda Kanjanasuwan, Thannika Thong-ard, Panupong Kowsurat, Isabelle Borghini-Fuhrer BMJ Global Health.2025; 10(4): e016720. CrossRef
Glucose-6-phosphate dehydrogenase deficiency induced hemolytic anemia and methemoglobinemia: a case report in a 7 -year-old female patient Adalgisa Fastuca, Antonio Vergori, Giuseppe Robustelli, Chiara Piccolo, Maria Ragazzo, Maddalena Marinoni, Massimo Agosti Italian Journal of Pediatrics.2025;[Epub] CrossRef
Human genetic variations conferring resistance to malaria Xiaokun Zhang, Jie Wu, Yunxing Peng, Lan Luo, Lu Zhang, Xi Huang, Guoying Chen, Yirong Li, Haoan Yi Journal of Translational Medicine.2025;[Epub] CrossRef
Glucose-6-phosphate dehydrogenase variants in Kachin, Myanmar Zin Moon, Ja Moon Aung, Dorene VanBik, Hae Soo Yun, Sanghyun Lee, Sylvatrie-Danne Dinzouna-Boutamba, Zau Ring, Yeonchul Hong, Dong-Il Chung, Youn-Kyoung Goo Parasites, Hosts and Diseases.2025; 63(4): 360. CrossRef
Hematological Indicators of Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency in Malaria-Infected Individuals Donia Zaid Hazem, Esraa Adel Mahmood, Anfal Saleh Mohammed Malaysian Journal of Medicine and Health Sciences.2024; 20(1): 46. CrossRef
Single-Drop Blood Detection of Common G6PD Mutations in Thailand Based on Allele-Specific Recombinase Polymerase Amplification with CRISPR-Cas12a Punchalee Mungkalasut, Pattaraporn Nimsamer, Poonlarp Cheepsunthorn, Sunchai Payungporn, Chalisa Louicharoen Cheepsunthorn ACS Omega.2023; 8(47): 44733. CrossRef
Prevalence of G6PD deficiency and G6PD variants amongst the southern Thai population Manit Nuinoon, Rungnapha Krithong, Suputcha Pramtong, Piyawit Sasuk, Chompunuch Ngeaiad, Sathanan Chaimusik, Jiraporn Kanboonma, Orawan Sarakul PeerJ.2022; 10: e14208. CrossRef
Cytochrome P450 2D6 (CYP2D6) and glucose-6-phosphate dehydrogenase (G6PD) genetic variations in Thai vivax malaria patients: Implications for 8-aminoquinoline radical cure Kamonwan Chamchoy, Sirapapha Sudsumrit, Thanyapit Thita, Srivicha Krudsood, Rapatbhorn Patrapuvich, Usa Boonyuen, Paul O. Mireji PLOS Neglected Tropical Diseases.2022; 16(12): e0010986. CrossRef
Plasmodium vivax: the potential obstacles it presents to malaria elimination and eradication Kassahun Habtamu, Beyene Petros, Guiyun Yan Tropical Diseases, Travel Medicine and Vaccines.2022;[Epub] CrossRef
Alveolar echinococcosis (AE) caused by infection with E. multilocularis metacestode, represents one of the most fatal helminthic diseases. AE is principally manifested with infiltrative, proliferating hepatic mass, resembling primary hepatocellular carcinoma. Sometimes metastatic lesions are found in nearby or remote tissue. AE diagnosis largely depends on imaging studies, but atypical findings of imaging features frequently require differential diagnosis from other hepatic lesions. Serological tests may provide further evidence, while obtaining reliable AE materials is not easy. In this study, alternative antigens, specific to AE were identified by analyzing E. granulosus protoscolex proteins. An immunoblot analysis of E. granulosus protoscolex showed that a group of low-molecular-weight proteins in the range from 14 kDa to 16 kDa exhibited a sensitive and specific immune response to AE patient sera. Partial purification and proteomic analysis indicated that this protein group contained myosin, tubulin polymerization promoting protein, fatty-acid binding protein, uncharacterized DM9, heat shock protein 90 cochaperone tebp P-23, and antigen S. When the serological applicability of recombinant forms of these proteins was assessed using enzyme-linked immunosorbent assay, DM9 protein (rEgDM9) showed 90.1% sensitivity (73/81 sera tested) and 94.5% specificity (172/181 sera tested), respectively. rEgDM9 showed weak cross-reactions with patient sera from the transitional and chronic stages of cystic echinococcosis (3 to 5 stages). rEgDM9 would serve as a useful alternative antigen for serodiagnosis of both early- and advanced-stage AE cases.
Cerebral toxoplasmosis is often life-threatening in an immunocompromised patient due to delayed diagnosis and treatment. Several differential diagnoses could be possible only with preoperative brain images of cerebral toxoplasmosis which show multiple rim-enhancing lesions. Due to the rarity of cerebral toxoplasmosis cases in Korea, the diagnosis and treatment are often delayed. This paper concerns a male patient whose cerebral toxoplasmosis was activated 21 years post kidney transplantation. Brain open biopsy was decided to make an exact diagnosis. Cerebral toxoplasmosis was confirmed by immunohistochemistry and PCR analyses of the tissue samples. Although cerebral toxoplasmosis was under control with medication, the patient did not recover clinically and died due to sepsis and recurrent gastrointestinal bleeding.
Citations
Citations to this article as recorded by
Disseminated toxoplasmosis infection 20 years post kidney transplant Shaun Chandler, Lana Sundac, Carmel Hawley BMJ Case Reports.2024; 17(9): e260412. CrossRef
Sungim Choi, Heun Choi, Seong Yeon Park, Yee Gyung Kwak, Je Eun Song, So Youn Shin, Ji Hyeon Baek, Hyun-IL Shin, Hong Sang Oh, Yong Chan Kim, Joon-Sup Yeom, Jin-Hee Han, Min Jae Kim
Korean J Parasitol 2022;60(1):39-43. Published online February 23, 2022
Plasmodium vivax exhibits dormant liver-stage parasites, called hypnozoites, which can cause relapse of malaria. The only drug currently used for eliminating hypnozoites is primaquine. The antimalarial properties of primaquine are dependent on the production of oxidized metabolites by the cytochrome P450 isoenzyme 2D6 (CYP2D6). Reduced primaquine metabolism may be related to P. vivax relapses. We describe a case of 4 episodes of recurrence of vivax malaria in a patient with decreased CYP2D6 function. The patient was 52-year-old male with body weight of 52 kg. He received total gastrectomy and splenectomy 7 months before the first episode and was under chemotherapy for the gastric cancer. The first episode occurred in March 2019 and each episode had intervals of 34, 41, and 97 days, respectively. At the first and second episodes, primaquine was administered as 15 mg for 14 days. The primaquine dose was increased with 30 mg for 14 days at the third and fourth episodes. Seven gene sequences of P. vivax were analyzed and revealed totally identical for all the 4 samples. The CYP2D6 genotype was analyzed and intermediate metabolizer phenotype with decreased function was identified.
Citations
Citations to this article as recorded by
Ellagic Acid from Geranium thunbergii and Antimalarial Activity of Korean Medicinal Plants Hojong Jun, Joon-Hee Han, Min Hong, Fadhila Fitriana, Jadidan Hada Syahada, Wang-Jong Lee, Ernest Mazigo, Johnsy Mary Louis, Van-Truong Nguyen, Seok Ho Cha, Wanjoo Chun, Won Sun Park, Se Jin Lee, Sunghun Na, Soo-Ung Lee, Eun-Taek Han, Tae-Hyung Kwon, Jin- Molecules.2025; 30(2): 359. CrossRef
Characteristics of Plasmodium vivax apicomplexan amino acid transporter 8 (PvApiAT8) in the cationic amino acid transport Wang-Jong Lee, Ernest Mazigo, Jin-Hee Han, Seok Ho Cha Scientific Reports.2025;[Epub] CrossRef
Efficacy of Primaquine for the Radical Cure of Plasmodium vivax Malaria in Northeast Myanmar and the Impact of Cytochrome P450 2D6 Genotypes Weilin Zeng, Huaie Liu, Pallavi Malla, Yan Zhao, Lynette Menezes, Yaming Cao, Chengqi Wang, Zhaoqing Yang, Liwang Cui Clinical Infectious Diseases.2025; 81(2): 379. CrossRef
Evaluation of the antimalarial activity of SAM13-2HCl with morpholine amide (SKM13 derivative) against antimalarial drug-resistant Plasmodium falciparum and Plasmodium berghei infected ICR mice Hyelee Hong, Kwonmo Moon, Thuy-Tien Thi Trinh, Tae-Hui Eom, Hyun Park, Hak Sung Kim, Seon-Ju Yeo Parasites, Hosts and Diseases.2024; 62(1): 42. CrossRef
Identification of breeding habitats and kdr mutations in Anopheles spp. in South Korea Hyelee Hong, Tae-Hui Eom, Thuy-Tien Thi Trinh, Bao Duong Tuan, Hyun Park, Seon-Ju Yeo Malaria Journal.2023;[Epub] CrossRef
Cost-Benefit Analysis of Tafenoquine for Radical Cure of Plasmodium vivax Malaria in Korea Jiyeon Suh, Jung Ho Kim, Jong-Dae Kim, Changsoo Kim, Jun Yong Choi, Jeehyun Lee, Joon-Sup Yeom Journal of Korean Medical Science.2022;[Epub] CrossRef
Cytochrome P450 2D6 (CYP2D6) and glucose-6-phosphate dehydrogenase (G6PD) genetic variations in Thai vivax malaria patients: Implications for 8-aminoquinoline radical cure Kamonwan Chamchoy, Sirapapha Sudsumrit, Thanyapit Thita, Srivicha Krudsood, Rapatbhorn Patrapuvich, Usa Boonyuen, Paul O. Mireji PLOS Neglected Tropical Diseases.2022; 16(12): e0010986. CrossRef
The Japanese amberjack Seriolae quinqueradiata is one of the most consumed fish species among the Koreans. However, information regarding parasitic infection in Japanese amberjack is scarce. This study described the morphological and molecular characteristics of a species of philometrid nematode, Philometroides seriolae, which was recovered from Japanese amberjack. This fish was caught in the sea of Goseong-gun, Gangwon-do, Republic of Korea (Korea). Six P. seriolae (Nematoda: Philometridae) were recovered from 2 Japanese amberjacks. These parasites were subgravid female which were 325-420 mm long and 2.95-3.27 mm wide. Furthermore, they had typical papillae distributed on their body surface with 14 papillae at the apical view. Sequence analysis of the small subunits of ribosomal RNA (SSU rRNA) showed high sequence identity (99.8%, 1,607/1,611-bp) with that of P. seriolae (GenBank accession no. FJ155811). This nematode species has been newly added to the Korean nematode fauna.
Citations
Citations to this article as recorded by
Seasonal change and phylogenetic position of Kamegainema cingula (Nematoda: Dracunculidae) parasitic in Japanese giant salamanders Karin Tsuchida, Misako Urabe, Kanto Nishikawa International Journal for Parasitology: Parasites and Wildlife.2025; 26: 101052. CrossRef
On the Evolutionary History of Philometridae (Nematoda: Dracunculoidea): Integrative Taxonomy Reveals Evidence of Character Diversification and Host–Parasite Cophylogenetic Patterns Lorena Gisela Ailán-Choke, Fabiano Paschoal, João Victor Couto, Felipe Bisaggio Pereira Diversity.2023; 15(6): 763. CrossRef
Parasites in the Skeletal Muscle of Amberjacks Seriola spp. in Japan: A Review Kazuo Ogawa Fish Pathology.2023; 58(4): 127. CrossRef
Global efforts to identify groups at high risk for schistosomiasis have mainly concentrated on identifying their geographical distribution. Investigations on the socioeconomic characteristics of high-risk groups are relatively scarce. This study aimed to explore the associations between schistosomiasis among students and their parents’ occupations. A nationwide cross-sectional survey was conducted targeting 105,167 students in 1,772 primary schools across Sudan in 2017. From these students, 100,726 urine and 96,634 stool samples were collected to test for Schistosoma haematobium and S. mansoni infection. A multi-level mixed effect analysis was used with age and sex as fixed factors, and school as a random factor. The odd ratios (ORs) of practicing open defecation among farmers’ children were almost 5 times higher than their counterparts whose parents were government officials (OR=4.97, 95% confidence intervals (CIs): 4.57-5.42, P<0.001). The ORs of contacting water bodies for watering livestock among farmers’ children were more than 4 times higher than those of children whose parents were government officials (OR=4.59, 95% CIs: 4.02-5.24, P<0.001). This study shows that schistosomiasis represents a disease of poverty and that farmers’ children constituted a high-risk group.
Citations
Citations to this article as recorded by
Using zero-inflated and hurdle regression models to analyze schistosomiasis data of school children in the southern areas of Ghana Kojo Nketia, Dziedzom K. de Souza, Jean Coulibaly PLOS ONE.2024; 19(7): e0304681. CrossRef
Prevalence and Risk Factors of Schistosomiasis in Sudan: A Systematic Review and Meta-Analysis Yousef Alsaafin, Ayman Omer, Osama Felemban, Sarra Modawi, Maydolin Ibrahim, Abdullah Mohammed, Ammar Elfaki, Ahmed Abushara, Maryam A SalahEldin Cureus.2024;[Epub] CrossRef
Identifying the risk factors of schistosomiasis in Indonesia Christine Christine, Herlina Susanto Sunuh, Fellysca Veronica Margareth Politon, Diana Vanda Daturara Doda Healthcare in Low-resource Settings.2023;[Epub] CrossRef
When free-ranging birds are accidentally killed or die, there may be greater potential for their associated ticks to detach, seek alternate hosts, and become established. We examined 711 carcasses of 95 avian species for ticks at a stopover island of migratory birds in the Republic of Korea where only Ixodes nipponensis and I. persulcatus were previously reported from local mammals and vegetation. A total of 16 ticks, I. turdus and Haemaphysalis flava, were collected from 8 fresh carcasses belonging to 5 avian species. Despite their known abundance on migratory birds and mainland Korea, these species had not colonized the isolated insular ecosystem possibly due to the low abundance and diversity of local hosts. The results imply that increasing human impact, such as the anthropogenic mortality of migratory birds and the introduction of non-native mammalian hosts, will increase the potential invasion and colonization risk of ticks. This finding also suggests that tick surveillance consisting of fresh carcasses of dead migratory birds may provide additional information, often ignored in surveillance of ticks on live birds, for the potential introduction of non-native ticks and associated pathogens affecting animal and human health.
Citations
Citations to this article as recorded by
Comparative population genetic structure of the mitochondrial 16S ribosomal RNA gene of Haemaphysalis flava (Acari: Ixodidae) between Nantong, China, and regions along the East Asia-Australasian Flyway Jing Su, Wei-Bing Zhang, Bin Sun, Xin Zhang, Yun-Peng Zhai, Jian-Ming Yuan Experimental and Applied Acarology.2025;[Epub] CrossRef
Ixodid ticks from wild and domestic animals in East and Central Asian flyways Hye-Ryung Byun, Mi-Sun Rieu, Sun-Woo Han, Seong-Ryeong Ji, Hyun-Young Nam, Seulgi Seo, Chang-Yong Choi, Bui Khanh Linh, Hien Le Thanh, Morakot Kaewthamasorn, Ana Sahara, Remil L. Galay, Shang-Lin Wang, Tuvshinjargal Erdenechimeg, Nyambayar Batbayar, Shin Acta Tropica.2024; 249: 107091. CrossRef
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a zoonotic, tick-borne RNA virus of the genus Bandavirus (Family Phenuiviridae), mainly reported in China, Japan, and the Republic of Korea (Korea). For the purpose of this study, a total of 3,898 adult and nymphal ticks of species Haemaphysalis longicornis (94.2%), Haemaphysalis flava (5.0%), Ixodes nipponensis (0.8%), and 1 specimen of Ixodes ovatus, were collected from the Deogyusan National Park, Korea, between April 2016 and June 2018. A single-step reverse transcriptase–nested PCR was performed, targeting the S segment of the SFTSV RNA. Total infection rate (IR) of SFTSV in individual ticks was found to be 6.0%. Based on developmental stages, IR was 5.3% in adults and 6.0% in nymphs. The S segment sequences obtained from PCR were divided into 17 haplotypes. All haplotypes were phylogenetically clustered into clades B-2 and B-3, with 92.7% sequences in B-2 and 7.3% in B-3. These observations indicate that the Korean SFTSV strains were closer to the Japanese than the Chinese strains. Further epidemiological studies are necessary to better understand the characteristics of the Korean SFTSV and its transmission cycle in the ecosystem.
Citations
Citations to this article as recorded by
Aspartate aminotransferase to platelet ratio correlates with poor prognosis and metabolic alterations in Dabie bandavirus infection Chunxia Guo, Ruixue Li, Xia Wang, Xiulan Peng Frontiers in Immunology.2025;[Epub] CrossRef
Establishment of a genotyping criteria for Bandavirus dabieense and confirmation of new genotypes Bingyan Liu, Tengfei He, Changtai Wang, Guomei Xia, Shijun Zhou, Shanshan Sun, Xinlei Chen, Xiaodan Hong, Jie Zhu, Zhenhua Zhang Scientific Reports.2025;[Epub] CrossRef
Molecular identification of severe fever with thrombocytopenia syndrome virus in deer ked: Implications for disease transmission Mark Anthony B. Casel, Jeong Ho Choi, Hyunwoo Jang, Seung-gyu Jang, Juryeon Gil, Rare Rollon, So-youn Cheun, Isaac Choi, Eun-ha Kim, Young-Il Kim, Young Ki Choi One Health.2025; 21: 101107. CrossRef
Alarming implications: severe fever with thrombocytopenia syndrome and its biological vectors in the context of climate change Ze Chen, Manoj Baranwal, Albert A. Rizvanov, Mohammed Okely, Svetlana F. Khaiboullina Frontiers in Microbiology.2025;[Epub] CrossRef
Comparative population genetic structure of the mitochondrial 16S ribosomal RNA gene of Haemaphysalis flava (Acari: Ixodidae) between Nantong, China, and regions along the East Asia-Australasian Flyway Jing Su, Wei-Bing Zhang, Bin Sun, Xin Zhang, Yun-Peng Zhai, Jian-Ming Yuan Experimental and Applied Acarology.2025;[Epub] CrossRef
A new record of Ixodes ovatus (Ixodida: Ixodidae) from the Kingdom of Bhutan Satoshi Shimano, Shimpei F. Hiruta, Tsukasa Waki, Indra Prasad Acharja, Pema Khandu, Jigme Tshering, Tshering Dorji, Takeo Yamauchi Journal of the Acarological Society of Japan.2025; 34(1): 11. CrossRef
First Report of Bandavirus dabieense in Bats and Ticks Collected from Bat Habitats Hye-Ryung Byun, Su-Jin Chae, Seong-Ryeong Ji, Jaehyoung Chong, Chul-Un Chung, Bumseok Kim, Hyesung Jeong, Joon-Seok Chae Vector-Borne and Zoonotic Diseases.2025; 25(11): 671. CrossRef
Viruses and Ticks: An Integrative Review of Virological Findings in Ticks Lucas Henrique da Silva e Silva, Fábio Silva da Silva, Daniel Damous Dias, Sâmia Luzia Sena da Silva, Lucia Aline Moura Reis, Hanna Carolina Farias Reis, Bruna Laís Sena do Nascimento, Joaquim Pinto Nunes Neto Arthropoda.2025; 3(4): 16. CrossRef
Molecular Prevalence and Phylogeny of Tick‐Borne Viruses in Meat and Dairy Products in the Republic of Korea Yeeun Seo, Md. Iqbal Hossain, Zhaoqi Wang, Daseul Yeo, Soontag Jung, Seoyoung Woo, Yuan Zhang, Min Suk Rhee, Changsun Choi, Daniel Diaz Transboundary and Emerging Diseases.2024;[Epub] CrossRef
Vaccine Development for Severe Fever with Thrombocytopenia Syndrome Virus in Dogs Seok-Chan Park, Da-Eun Jeong, Sun-Woo Han, Joon-Seok Chae, Joo-Yong Lee, Hyun-Sook Kim, Bumseok Kim, Jun-Gu Kang Journal of Microbiology.2024; 62(4): 327. CrossRef
Molecular surveillance of zoonotic pathogens from wild rodents in the Republic of Korea Kyoung-Seong Choi, Sunwoo Hwang, Myung Cheol Kim, Hyung-Chul Cho, Yu-Jin Park, Min-Jeong Ji, Sun-Woo Han, Joon-Seok Chae, Colleen B. Jonsson PLOS Neglected Tropical Diseases.2024; 18(7): e0012306. CrossRef
Double-Stranded RNA-Based Method for Diagnosing Severe Fever with Thrombocytopenia Jung Wan Park, Jaemin Jeon, Yoosik Kim, Min Hyok Jeon Journal of Clinical Medicine.2024; 14(1): 105. CrossRef
Severe fever with thrombocytopenia syndrome virus from ticks: a molecular epidemiological study of a patient in the Republic of Korea Seong Yoon Kim, Choong Won Seo, Hee Il Lee Experimental and Applied Acarology.2023; 89(2): 305. CrossRef
Coinfection of Severe Fever With Thrombocytopenia Syndrome Virus and Coxiella burnetii in Developmental Stage of Hard Ticks in Subtropical Region of Korea Jeong Rae Yoo, Sang Taek Heo, Misun Kim, Miyeon Kim, Myeong Jin Kang, Eui Tae Kim, Su Yeon Kang, Keun Hwa Lee Journal of Korean Medical Science.2023;[Epub] CrossRef
Transcriptome analysis of Haemaphysalis flava female using Illumina HiSeq 4000 sequencing: de novo assembly, functional annotation and discovery of SSR markers Min Kyu Sang, Hongray Howrelia Patnaik, Jie Eun Park, Dae Kwon Song, Jun Yang Jeong, Chan Eui Hong, Yong Tae Kim, Hyeon Jun Shin, Liu Ziwei, Hee Ju Hwang, So Young Park, Se Won Kang, Seung-Hwan Park, Sung-Jae Cha, Jung Ho Ko, E. Hyun Shin, Hong Seog Park, Parasites & Vectors.2023;[Epub] CrossRef
SFTSV infection in rodents and their ectoparasitic chiggers Xiao-Lan Gu, Wen-Qing Su, Chuan-Min Zhou, Li-Zhu Fang, Ke Zhu, Dong-Qiang Ma, Fa-Chun Jiang, Ze-Min Li, Dan Li, Shu-Hui Duan, Qiu-Ming Peng, Rui Wang, Yuan Jiang, Hui-Ju Han, Xue-Jie Yu, Masayuki Saijo PLOS Neglected Tropical Diseases.2022; 16(8): e0010698. CrossRef
First
Prev
