Parasites, Hosts and Diseases

"Feng Meng"

Brief Communication

Seroprevalence of Encephalitozoon cuniculi and Toxoplasma gondii in domestic rabbits (Oryctolagus cuniculus) in China: Qing-Feng Meng, Wei-Lin Wang, Xiao-Ting Ni, Hai-Bin Li, Gui-Zhe Yao, Xiao-Lin Sun, Wei-Li Wang, Wei Cong; Korean J Parasitol 2015;53(6):759-763.
Published online December 31, 2015; DOI: https://doi.org/10.3347/kjp.2015.53.6.759

Abstract
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The breeding of domestic rabbits (Oryctolagus cuniculus) for human consumption has a long tradition in China. Infections that can affect the production of meat or even be transmitted from animals to humans are important to monitor, especially for public health reasons as well as for their impact on animal health. Thus, a total of 1,132 domestic rabbit sera from 4 regions in China were collected for serological screening for Encephalitozoon cuniculi and for Toxoplasma gondii by ELISA and modified agglutination test (MAT), respectively. Antibodies to E. cuniculi were detected in 248/1,132 (21.9%) sera tested while antibodies against T. gondii revealed a seroprevalence of 51/1,132 (4.5%). We believe that the present results are of epidemiological implications and public health importance due to the acknowledged susceptibility of humans to E. cuniculi and T. gondii infections. Therefore, routine screening tests of domestic rabbits are proposed considering the zoonotic potential of these parasites.

Citations

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The Prevalence of Encephalitozoon cuniculi in Domestic Rabbits (Oryctolagus cuniculus) in the North-Western Region of Romania Using Serological Diagnosis: A Preliminary Study
Anca-Alexandra Doboși, Anamaria Ioana Paștiu, Lucia-Victoria Bel, Dana Liana Pusta
Microorganisms.2024; 12(7): 1440. CrossRef
Serological survey for antibodies to Encephalitozoon cuniculi and Toxoplasma gondii in pet rabbits in eastern coastal areas of China
Yong WANG, Xuling QIN, Xiuguo DIAO, Yongxia LIU, Jianzhu LIU
Journal of Veterinary Medical Science.2022; 84(6): 777. CrossRef
Epidemiological and Public Health Significance of Toxoplasma gondii Infection in Wild Rabbits and Hares: 2010–2020
Sonia Almeria, Fernando H. A. Murata, Camila K. Cerqueira-Cézar, Oliver C. H. Kwok, Alicia Shipley, Jitender P. Dubey
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Relationship between seropositivity of Encephalitozoon cuniculi and renal biochemical markers in clinically healthy rabbits
Özcan ÖZKAN, Banuçiçek YÜCESAN, Selçuk PEKKAYA, Mehmet Eray ALÇIĞIR, İsmayil Safa GÜRCAN
Ankara Üniversitesi Veteriner Fakültesi Dergisi.2019; 66(2): 197. CrossRef
Occurrence and genetic characterization of Toxoplasma gondii and Neospora caninum in slaughtered domestic rabbits in central China
Weifeng Qian, Wenchao Yan, Chaochao Lv, Rongzhen Bai, Tianqi Wang
Parasite.2019; 26: 36. CrossRef
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Mina Henneb, Khaled Harhoura, Mohamed Amine Bekara, Safia Zenia, Miriem Aissi
Veterinary World.2019; 12(6): 855. CrossRef
Seroprevalence of Toxoplasma gondii and Encephalitozoon cuniculi among domestic rabbits in central China
Shuai Wang, Zhijun Yao, Lingjuan Li, Yaoqian Pan, Pengju Li, Xiaoxu Nan, Qing Xie, Zhenchao Zhang
Parasite.2018; 25: 9. CrossRef
Rapid detection of three rabbit pathogens by use of the Luminex x-TAG assay
Miaoli Wu, Yujun Zhu, Feng Cong, Dan Rao, Wen Yuan, Jing Wang, Bihong Huang, Yuexiao Lian, Yu Zhang, Ren Huang, Pengju Guo
BMC Veterinary Research.2018;[Epub] CrossRef

9,580 View
108 Download
10 Web of Science
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Original Article

Sensitivity of Plasmodium falciparum to Antimalarial Drugs in Hainan Island, China: Shan-Qing Wang, Guang-Ze Wang, Yu-Chun Li, Feng Meng, Shi-Gan Lin, Zhen-Hu Zhu, Ding-Wei Sun, Chang-Hua He, Xi-Min Hu, Jian-Wei Du; Korean J Parasitol 2015;53(1):35-41.
Published online February 27, 2015; DOI: https://doi.org/10.3347/kjp.2015.53.1.35

Abstract
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Pyronaridine and artesunate have been shown to be effective in falciparum malaria treatment. However, pyronaridine is rarely used in Hainan Island clinically, and artesunate is not widely used as a therapeutic agent. Instead, conventional antimalarial drugs, chloroquine and piperaquine, are used, explaining the emergence of chloroquine-resistant Plasmodium falciparum. In this article, we investigated the sensitivity of P. falciparum to antimalarial drugs used in Hainan Island for rational drug therapy. We performed in vivo (28 days) and in vitro tests to determine the sensitivity of P. falciparum to antimalarial drugs. Total 46 patients with falciparum malaria were treated with dihydroartemisinin/piperaquine phosphate (DUO-COTECXIN) and followed up for 28 day. The cure rate was 97.8%. The mean fever clearance time (22.5±10.6 hr) and the mean parasite clearance time (27.3±12.2 hr) showed no statistical significance with different genders, ages, temperatures, or parasite density (P>0.05). The resistance rates of chloroquine, piperaquine, pyronarididine, and artesunate detected in vitro were 71.9%, 40.6%, 12.5%, and 0%, respectively (P<0.0001). The resistance intensities decreased as follows: chloroquine>piperaquine>pyronarididine>artesunate. The inhibitory dose 50 (IC₅₀) was 3.77×10^-6 mol/L, 2.09×10^-6 mol/L, 0.09×10^-6 mol/L, and 0.05×10^-6 mol/L, and the mean concentrations for complete inhibition (CIMC) of schizont formation were 5.60×10^-6 mol/L, 9.26×10^-6 mol/L, 0.55×10^-6 mol/L, and 0.07×10^-6 mol/L, respectively. Dihydroartemisinin showed a strong therapeutic effect against falciparum malaria with a low toxicity.

Citations

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Evaluation Algorithm of Volleyball Players’ Competitive Ability Based on the Random Matrix Model
Tailin Wang, Hua Zheng, Fangshu Li, Nian Jia, Zengliang Cai, Ning Cao
Mathematical Problems in Engineering.2022; 2022: 1. CrossRef

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104 Download
2 Web of Science
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Case Report

A Case of Plasmodium ovale wallikeri Infection in a Chinese Worker Returning from West Africa: Yuchun Li, Guangze Wang, Dingwei Sun, Feng Meng, Shigan Lin, Ximin Hu, Shanqing Wang; Korean J Parasitol 2013;51(5):557-562.
Published online October 31, 2013; DOI: https://doi.org/10.3347/kjp.2013.51.5.557

Abstract
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In contrast to the gradual reduction in the number of locally transmitted malaria cases in China, the number of imported malaria cases has been increasing since 2008. Here, we report a case of a 39-year-old Chinese man who acquired Plasmodium ovale wallikeri infection while staying in Ghana, West Africa for 6 months in 2012. Microscopic examinations of Giemsa-stained thin and thick blood smears indicated Plasmodium vivax infection. However, the results of rapid diagnostic tests, which were conducted 3 times, were not in agreement with P. vivax. To further check the diagnosis, standard PCR analysis of the small-subunit rRNA gene was conducted, based on which a phylogeny tree was constructed. The results of gene sequencing indicated that this malaria is a variant of P. ovale (P. ovale wallikeri). The infection in this patient was not a new infection, but a relapse of the infection from the one that he had contracted in West Africa.

Citations

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Geographical origin of Plasmodium vivax in the Hainan Island, China: insights from mitochondrial genome
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Malaria Journal.2023;[Epub] CrossRef
An innovative three-layer strategy in response to a quartan malaria outbreak among forest goers in Hainan Island, China: a retrospective study
Yuchun Li, Yingjuan Huang, Renqiang Chen, Weizhen Huang, Huanzhi Xu, Rongshen Ye, Shaoling Huang, Ji Zhen, Xiaodan Wen, Guoyi Wang, Yong Liu, Haishan Li, Zaichun Zheng, Jian Wang, Guoshen Wang, Chong Chen, Wen Zeng, Feng Meng, Xiaoming Huang, Guangze Wang
Infectious Diseases of Poverty.2022;[Epub] CrossRef
High frequency of the Duffy-negative genotype and absence of Plasmodium vivax infections in Ghana
Charles A. Brown, Prince J. Pappoe-Ashong, Nancy Duah, Anita Ghansah, Harry Asmah, Edwin Afari, Kwadwo A. Koram
Malaria Journal.2021;[Epub] CrossRef
A comparison of two PCR protocols for the differentiation of Plasmodium ovale species and implications for clinical management in travellers returning to Germany: a 10-year cross-sectional study
Hagen Frickmann, Christine Wegner, Stefanie Ruben, Ulrike Loderstädt, Egbert Tannich
Malaria Journal.2019;[Epub] CrossRef
Indel-informed Bayesian analysis suggests cryptic population structure between Plasmodium knowlesi of humans and long-tailed macaques (Macaca fascicularis) in Malaysian Borneo
JustinJ.S. Wilcox, Abigail Kerschner, Hope Hollocher
Infection, Genetics and Evolution.2019; 75: 103994. CrossRef
Detection of malaria with light microscopy and Nested polymerase chain reaction (Nested PCR) methods in peripheral blood expansions and investigation of the genetic diversity of Plasmodium species by 18S rRNA gene in Southeast of Iran
Ahmad Taghdiri, Pooya Ghasemi Nejad Almani, Iraj Sharifi, Mohammad Ali Mohammadi, Samira Salari
Microbial Pathogenesis.2019; 137: 103782. CrossRef
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Infection, Genetics and Evolution.2018;[Epub] CrossRef
Diagnosis of an imported Plasmodium ovale wallikeri infection in Malaysia
Jonathan Wee Kent Liew, Rohela Mahmud, Lian Huat Tan, Yee Ling Lau
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Clinical implications of a gradual dormancy concept in malaria
Joachim Richter, Gabriele Franken, Martha C. Holtfreter, Susanne Walter, Alfons Labisch, Heinz Mehlhorn
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Genetic diversity of Plasmodium vivax population before elimination of malaria in Hainan Province, China
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Molecular characterization of misidentified Plasmodium ovale imported cases in Singapore
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Robin H. Miller, Clifford O. Obuya, Elizabeth W. Wanja, Bernhards Ogutu, John Waitumbi, Shirley Luckhart, V. Ann Stewart, Alain Debrabant
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