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"Xuelian Bai"

Brief Communication

Recent Incidence of Paragonimus westermani Metacercariae in Freshwater Crayfish, Cambaroides similis, from Two Enzootic Sites in Jeollanam-do, Korea
Jin-Ho Song, Fuhong Dai, Xuelian Bai, Tae-Im Kim, Hyun-Jong Yang, Tong-Soo Kim, Shin-Hyung Cho, Sung-Jong Hong
Korean J Parasitol 2017;55(3):347-350.
Published online June 30, 2017
DOI: https://doi.org/10.3347/kjp.2017.55.3.347
An epidemiological study was performed to know the recent infection status of Paragonimus westermani metacercariae (PwMc) in freshwater crayfish, Cambaroides similis, from 2 streams in Jeollanam-do, Republic of Korea. Crayfish were collected from creeks in Bogil-do (Island), Wando-gun, and in a creek near Daeheung Temple in Haenam-gun. The infection rate of crayfish with PwMc in Bogil-do was 89.8%, and the metacercarial burden was 37 PwMc per the infected crayfish. Crayfish in a creek near Daeheung Temple were larger and twice heavier than those in Bogil-do. Of them, 96.5% were infected with PwMc. An average of 140 metacercariae was found in the infected crayfish, almost quadruple to those of Bogil-do. There was a strong correlation between the number of PwMc and body weight of the crayfish. These results suggest that P. westermani metacercariae are still prevalent in crayfish of the 2 regions in Jeollanam-do, Korea.

Citations

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  • Physical habitat characteristics of freshwater crayfish Cambaroides similis (Koelbel, 1892) (Arthropoda, Decapoda) in South Korea
    Jin-Young Kim, Yong Ju Kwon, Ye Ji Kim, Yeong-Deok Han, Jung Soo Han, Chae Hui An, Yong Su Park, Dongsoo Kong
    Journal of Ecology and Environment.2023;[Epub]     CrossRef
  • Morphological and Molecular Characterization of Paragonimus skrjabini Complex from Yunnan, China: A Brief Report
    Qiu-Hong Shu, Shu-De Li, Ming Tian, Yong Meng, Shu-Mei-Qi He, Min Zhu, Miao-Miao Wang, Wen-Lin Wang
    Acta Parasitologica.2022; 67(1): 316.     CrossRef
  • What Findings on Chest CTs Can Delay Diagnosis of Pleuropulmonary Paragonimiasis?
    Kai Ke Li, Gong Yong Jin, Keun Sang Kwon
    Tomography.2022; 8(3): 1493.     CrossRef
  • Paragonimus and its hosts in China: An update
    Xiao-Juan Zhou, Qian Yang, Qi-Hong Tan, Li-Yanyang Zhang, Lin-Bo Shi, Jie-Xin Zou
    Acta Tropica.2021; 223: 106094.     CrossRef
  • Morphological and Molecular Characterization of Paragonimus Species Isolated from Freshwater Crabs in Southern Yunnan, China
    Qiu-Hong Shu, Yang Yang, Miao-Miao Wang, Shu-De Li, Ming Tian, Wen-Wei Bai, Yong Meng, Shu-Mei-Qi He, Wen-Lin Wang, Maoshui Wang
    Journal of Tropical Medicine.2021; 2021: 1.     CrossRef
  • Paragonimus and paragonimiasis in Asia: An update
    Ayako Yoshida, Pham Ngoc Doanh, Haruhiko Maruyama
    Acta Tropica.2019; 199: 105074.     CrossRef
  • Artemisinin and its derivatives in treating helminthic infections beyond schistosomiasis
    Nelson Siukei Lam, Xinxin Long, Xin-zhuan Su, Fangli Lu
    Pharmacological Research.2018; 133: 77.     CrossRef
  • A Case of Pulmonary Paragonimiasis with Chronic Abdominal Pain and Erythematous Rash in a 6-year-old Girl
    Ju Young Kim, Min Kyu Park, Yong Ju Lee, Sun Huh, Ky Young Cho
    Pediatric Infection and Vaccine.2018; 25(1): 54.     CrossRef
  • 10,191 View
  • 169 Download
  • 8 Web of Science
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Original Article
Identification and Molecular Characterization of Parkin in Clonorchis sinensis
Xuelian Bai, Tae Im Kim, Ji-Yun Lee, Fuhong Dai, Sung-Jong Hong
Korean J Parasitol 2015;53(1):65-75.
Published online February 27, 2015
DOI: https://doi.org/10.3347/kjp.2015.53.1.65

Clonorchis sinensis habitating in the bile duct of mammals causes clonorchiasis endemic in East Asian countries. Parkin is a RING-between-RING protein and has E3-ubiquitin ligase activity catalyzing ubiquitination and degradation of substrate proteins. A cDNA clone of C. sinensis was predicted to encode a polypeptide homologous to parkin (CsParkin) including 5 domains (Ubl, RING0, RING1, IBR, and RING2). The cysteine and histidine residues binding to Zn2+ were all conserved and participated in formation of tertiary structural RINGs. Conserved residues were also an E2-binding site in RING1 domain and a catalytic cysteine residue in the RING2 domain. Native CsParkin was determined to have an estimated molecular weight of 45.7 kDa from C. sinensis adults by immunoblotting. CsParkin revealed E3-ubiquitin ligase activity and higher expression in metacercariae than in adults. CsParkin was localized in the locomotive and male reproductive organs of C. sinensis adults, and extensively in metacercariae. Parkin has been found to participate in regulating mitochondrial function and energy metabolism in mammalian cells. From these results, it is suggested that CsParkin play roles in energy metabolism of the locomotive organs, and possibly in protein metabolism of the reproductive organs of C. sinensis.

Citations

Citations to this article as recorded by  Crossref logo
  • Characterization of a novel organic solute transporter homologue from Clonorchis sinensis
    Yanyan Lu, Won Gi Yoo, Fuhong Dai, Ji-Yun Lee, Jhang Ho Pak, Woon-Mok Sohn, Sung-Jong Hong, John Pius Dalton
    PLOS Neglected Tropical Diseases.2018; 12(4): e0006459.     CrossRef
  • Molecular and structural characteristics of multidrug resistance-associated protein 7 in Chinese liver fluke Clonorchis sinensis
    Fuhong Dai, Won Gi Yoo, Ji-Yun Lee, Yanyan Lu, Jhang Ho Pak, Woon-Mok Sohn, Sung-Jong Hong
    Parasitology Research.2017; 116(3): 953.     CrossRef
  • 14,096 View
  • 98 Download
  • 3 Web of Science
  • Crossref