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Evaluation of specific IgE antibody in Clonorchis sinensis infection
Duk Young Min and Chin-Thack Soh
Department of Parasitology, Yonsei University Medical College, Institute of Tropical Medicine, Yonsei University, Korea.
Abstract
Serum IgE level and Clonorchis specific IgE in individuals with Clonorchis sinensis were determined by radioimmunosorbent(RIST) and radioallergosorbent technique(RAST) respectively. Highly significant elevations of serum IgE (P<0.001) and specific IgE antibodies (P<0.01) were observed in area from individuals with clonorchiasis.
The mean values of serum IgE in individuals with clonorchiasis and healthy individuals were 2,372 IU/ml and 364 IU/ml respectively and specific IgE antibodies of both groups were 52.0 and 4.4%. A close correlation(r=0.9451) between serum IgE level and specific IgE antibodies were observed and correlation (r=0.6056) between serum IgE and EPG and between specific IgE and EPG(r=0.5693) were also observed.
Tables
Table 1 Sex, age and EPG(eggs per gram of feces) of 21 clonorchiasis patients
Table 2 Serum IgE and Clcncrchis specific IgE levels in 15 healthy individuals
Table 3 Serum IgE and Clonorchis-specific IgE levels in 21 individuals infected with Clonorchis sinensis
Table 4 Comparison of serum IgE and Clonorchis specific IgE levels between individuals infected with Clonorchis sinensis and healthy individuals
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