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Case Report

A Paragonimiasis Patient with Allergic Reaction to Praziquantel and Resistance to Triclabendazole: Successful Treatment after Desensitization to Praziquantel

Sun Young Kyung1, Yong Kyun Cho1, Yu Jin Kim1, Jeong-Woong Park1, Sung Hwan Jeong1, Jae-Ik Lee2, Yon Mi Sung3, Sang Pyo Lee1
The Korean Journal of Parasitology 2011;49(1):73-77.
Published online: March 18, 2011

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Corresponding author (allergy21@hotmail.com)
• Received: September 6, 2010   • Revised: December 6, 2010   • Accepted: December 11, 2010

© 2011, Korean Society for Parasitology

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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A Paragonimiasis Patient with Allergic Reaction to Praziquantel and Resistance to Triclabendazole: Successful Treatment after Desensitization to Praziquantel
Korean J Parasitol. 2011;49(1):73-77.   Published online March 18, 2011
DOI: https://doi.org/10.3347/kjp.2011.49.1.73
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A Paragonimiasis Patient with Allergic Reaction to Praziquantel and Resistance to Triclabendazole: Successful Treatment after Desensitization to Praziquantel
Korean J Parasitol. 2011;49(1):73-77.   Published online March 18, 2011
DOI: https://doi.org/10.3347/kjp.2011.49.1.73
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A Paragonimiasis Patient with Allergic Reaction to Praziquantel and Resistance to Triclabendazole: Successful Treatment after Desensitization to Praziquantel
Image Image Image
Fig. 1 CT scan of the chest of a 46-year-old female diagnosed with P. westermani showed an approximately 3.2×2.8 cm sized heterogeneously enhanced mass-like consolidation (arrow) in the anterior segment of the right upper lobe, which was attached to the mediastinal pleura.
Fig. 2 Histologic findings of percutaneous needle biopsy specimens from the lung showed abundant inflammatory cells, including many eosinophils, some granulomas, and necrotic cellular debris. H-E stain, ×400.
Fig. 3 The changes of the percentage of eosinophils and anti-P. westermani IgG antibody titer over time in a 46-year-old female who was diagnosed with P. westermani and received treatments with triclabendazole and praziquantel. The anti-P. westermani IgG titers as measured by micro-ELISA are expressed as the optical density at 405 nm.

Fig. 1

Fig. 2

Fig. 3

A Paragonimiasis Patient with Allergic Reaction to Praziquantel and Resistance to Triclabendazole: Successful Treatment after Desensitization to Praziquantel
PHD : Parasites, Hosts and Diseases

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