Hemagglutinin (HA) titers to sRBC were chronologically observed in chickens orally inoculated at 2 days of age with 5 x 10(5) oocysts of Cryptosporidium baileyi. All the infected chickens exhibited negligible HA titers by 44 days postinoculation (PI). The titers were elevated as time progressed, and peaked on day 52 PI, declined gradually thereafter, and eventually reached to normal titers on day 92 PI. On the contrary, the titers in uninfected chickens were higher in comparison with infected chickens during the experiment. Chickens infected with the protozoa showed normal oocyst shedding profiles during this period. These data suggest that C. baileyi infection suppress development of humoral immunity to sRBC in chickens. It is possible that impairment of the bursa of Fabricius by cryptosporidiosis rendered chickens vulnerable to other pathogens.
Citations
Citations to this article as recorded by
Cryptosporidium baileyi and Mycoplasma synoviae co-infection enhances M. synoviae colonization and aggravates tissue damage in chickens Yiqing Zhang, Yi Li, Zhanxing Wang, Qingfeng Zhou, Zhuanqiang Yan, Nanshan Qi, Shenquan Liao, Xuhui Lin, Minna Lv, Haiming Cai, Yongle Song, Xiangjie Chen, Yibin Zhu, Juan Li, Mingfei Sun Frontiers in Microbiology.2026;[Epub] CrossRef
Reduced Serologic Response to Avian Influenza Vaccine in Specific-Pathogen-Free Chicks Inoculated with Cryptosporidium baileyi Y-X. Hao, J-M. Yang, C. He, Q. Liu, Tim A. McAllister Avian Diseases.2008; 52(4): 690. CrossRef
Effect of Cryptosporidium baileyi in specific pathogen free chickens vaccinated (CVI988/Rispens) and challenged with HPRS-16 strain of Marek's H. Abbassi, F. Coudert, G. Dambrine, Y. Chérel, M. Naciri Avian Pathology.2000; 29(6): 623. CrossRef
Cryptosporidiosis in birds — A review T. Sréter, I. Varga Veterinary Parasitology.2000; 87(4): 261. CrossRef
A review of the importance of cryptosporidiosis in farm animals Dirk C de Graaf, Emmanuel Vanopdenbosch, Luis M Ortega-Mora, Hayet Abbassi, Johan E Peeters International Journal for Parasitology.1999; 29(8): 1269. CrossRef
Immunosuppressive effect of Cryptosporidium baileyi infection on vaccination against avian infectious bronchitis in chicks J K Rhee, H J Yang, S Y Yook, H C Kim The Korean Journal of Parasitology.1998; 36(3): 203. CrossRef
Verification of immunosuppression in chicks caused by Cryptosporidium baileyi infection using Brucella abortus strain 1119-3 J K Rhee, H J Yang, H C Kim The Korean Journal of Parasitology.1998; 36(4): 281. CrossRef
Immunosuppressive effect of Cryptosporidium baileyi infection on vaccination against Newcastle disease in chicks J K Rhee, H C Kim, S B Lee, S Y Yook The Korean Journal of Parasitology.1998; 36(2): 121. CrossRef
