Sparganum infections in normal adult population and epileptic patients in Korea: A seroepidemiologic observation

, Kong, Yoon; , Cho, Seung Yull; , Kang, Woo Shik

doi:1994.32.2.85

Korean J Parasito > Volume 32(2):1994 > Article

Original Article


Korean J Parasitol. 1994 Jun;32(2):85-92. English. Published online Jun 20, 1994. http://dx.doi.org/10.3347/kjp.1994.32.2.85
Copyright © 1994 by The Korean Society for Parasitology


Sparganum infections in normal adult population and epileptic patients in Korea: A seroepidemiologic observation
Yoon Kong,^*¹Seung-Yull Cho,¹ and Woo Shik Kang²
¹Department of Parasitology, College of Medicine, Chung-Ang University, Seoul 153-756, Korea.
²The Changmi Club, Inchon, Korea.

Received April 11, 1994; Accepted May 19, 1994.
Abstract
A seroepidemiologic observation of anti-Spirometra erinacei plerocerciod (sparganum) antibody (IgG) in serum was made in normal adult and epileptic patients in Korea from February 1987 to September 1990. Sera were tested by enzyme-linked immunosorbent assay (ELISA) for anti-spaganum antibody together with anti-Taenia solium metacestode, and anti-Paragonimus westermani antibodies. Sera reacted positively to sparganum antigen only were considered. Positive rate for anti-sparganum antibody in 850 normal adults was 1.9% (standardized rate by provincial population was 1.7%). In 2,667 randomly selected patients of epilepsy at 28 local centers of the Changmi Club, positive rate was 2.5%(standardized rate: 2.3%). In both normal adult and patient groups, the higher antibody rates were observed in Kangwon and Chonnam province. Positive rates were 10 times higher in male than in female in normal adults and 4.5 times in male epileptic patients. The rates were elevated especially with age over 30-year. Odd ratio of the antibody was 1.32 which indicated an ambiguous etiologic factor for epilepsy.

Tables


	Table 1 Positive rate of anti-sparganum antibody (IgG) in sera from normal adult population (students, factory workers and employees of firm) in their periodic check-up


	Table 2 Age and sex distribution of tested cases and number of positive reactors in normal adult population


	Table 3 Positive rates of anti-sparganum antibody (IgG) in epileptic patients of the Changmi Club shown by local center and administrative district


	Table 4 Positive reactors of anti-sparganum antiody in 2,667 epileptic patients analysed by age and sex


	Table 5 Distribution of cases in different interbal in the antibody levels in the surveyed groups


	Table 6 Odds ratio of anit-sparganum and anti-Taenia solium metacestode antibodies for epilepsy between normal adult and epieptic patients

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