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Chronic Clonorchis sinensis (CS) infection is etiologically related to cholangiocarcinoma (CHCA) in human and animals.
This study was carried out to clarify the role of CS infection on dimethylnitrosamine (DMN)-induced cholangiocarcinogenesis. Fifteen hamsters were administered with 15 ppm DMN for 4 weeks and one week later, the hamsters were infected with 15 metacercariae of CS (DMN--
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Clonorchis sinensis and Cholangiocarcinoma Eun-Min Kim, Sung-Tae Hong Journal of Korean Medical Science.2025;[Epub] CrossRef
The Overactivation of NADPH Oxidase during Clonorchis sinensis Infection and the Exposure to N-Nitroso Compounds Promote Periductal Fibrosis Ji Hoon Jeong, Junyeong Yi, Myung Ki Hwang, Sung-Jong Hong, Woon-Mok Sohn, Tong-Soo Kim, Jhang Ho Pak Antioxidants.2021; 10(6): 869. CrossRef
Clonorchis sinensis and clonorchiasis Byoung-Kuk Na, Jhang Ho Pak, Sung-Jong Hong Acta Tropica.2020; 203: 105309. CrossRef
Research progress of cholangiocarcinoma induced by liver fluke infection Quan Liang Infection International.2018; 6(4): 112. CrossRef
Effect of Opisthorchis felineus infection and dimethylnitrosamine administration on the induction of cholangiocarcinoma in Syrian hamsters Galina A. Maksimova, Maria Y. Pakharukova, Elena V. Kashina, Natalya A. Zhukova, Anna V. Kovner, Maria N. Lvova, Alexey V. Katokhin, Tatyana G. Tolstikova, Banchob Sripa, Viatcheslav A. Mordvinov Parasitology International.2017; 66(4): 458. CrossRef
In-vivo monitoring of development of cholangiocarcinoma induced with C. sinensis and N-nitrosodimethylamine in Syrian golen hamsters using ultrasonography and magnetic resonance imaging: a preliminary study Hyunsik Woo, Joon Koo Han, Jung Hoon Kim, Sung-Tae Hong, Md. Hafiz Uddin, Ja-June Jang European Radiology.2017; 27(4): 1740. CrossRef
Infection with Opisthorchis felineus induces intraepithelial neoplasia of the biliary tract in a rodent model Maria João Gouveia, Maria Y Pakharukova, Thewarach Laha, Banchob Sripa, Galina A Maksimova, Gabriel Rinaldi, Paul J Brindley, Viatcheslav A Mordvinov, Teresina Amaro, Lucio Lara Santos, José Manuel Correia da Costa, Nuno Vale Carcinogenesis.2017; 38(9): 929. CrossRef
The morphofunctional and biochemical characteristics of opisthorchiasis-associated cholangiocarcinoma in a Syrian hamster model G. A. Maksimova, M. Y. Pakharukova, E. V. Kashina, N. A. Zhukova, M. N. Lvova, M. V. Khvostov, D. S. Baev, A. V. Katokhin, T. G. Tolstikova, V. A. Mordvinov Russian Journal of Genetics: Applied Research.2016; 6(4): 454. CrossRef
C3H/He Mice as an Incompatible Cholangiocarcinoma Model by Clonorchis sinensis, Dicyclanil and N-Nitrosodimethylamine Md. Hafiz Uddin, Shunyu Li, Yan Jin, Min-Ho Choi, Ja June Jang, Sung-Tae Hong The Korean Journal of Parasitology.2016; 54(3): 281. CrossRef
Antibodies against Clonorchis sinensis LDH could cross-react with LDHB localizing on the plasma membrane of human hepatocarcinoma cell SMMC-7721 and induce apoptosis Tianzhang Song, Wenjia Gan, Jintao Chen, Lilin Huang, Hongling Yin, Tailong He, Huaiqiu Huang, Xuchu Hu Parasitology Research.2016; 115(4): 1595. CrossRef
Involvement of PSMD10, CDK4, and Tumor Suppressors in Development of Intrahepatic Cholangiocarcinoma of Syrian Golden Hamsters Induced by Clonorchis sinensis and N-Nitrosodimethylamine Md. Hafiz Uddin, Min-Ho Choi, Woo Ho Kim, Ja-June Jang, Sung-Tae Hong, Xiao-Nong Zhou PLOS Neglected Tropical Diseases.2015; 9(8): e0004008. CrossRef
Genetic diversity of the Chinese liver fluke Clonorchis sinensis from Russia and Vietnam Galina N. Chelomina, Yulia V. Tatonova, Nguyen Manh Hung, Ha Duy Ngo International Journal for Parasitology.2014; 44(11): 795. CrossRef
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Expandable Metal Stents for Malignant Hilar Biliary Obstruction Christian Gerges, Brigitte Schumacher, Grischa Terheggen, Horst Neuhaus Gastrointestinal Endoscopy Clinics of North America.2011; 21(3): 481. CrossRef
Liver Flukes: the Malady Neglected Jae Hoon Lim Korean Journal of Radiology.2011; 12(3): 269. CrossRef
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Helminths and malignancy B. J. VENNERVALD, K. POLMAN Parasite Immunology.2009; 31(11): 686. CrossRef
Opisthorchiasis mimicking primary biliary cirrhosis as an indication for liver transplantation Nathaniel Melling, Werner Hohenberger, Süleyman Yedibela Journal of Hepatology.2009; 50(5): 1057. CrossRef
Resistance of cholangiocarcinoma cells to parthenolide-induced apoptosis by the excretory–secretory products of Clonorchis sinensis Young Ju Kim, Min-Ho Choi, Sung-Tae Hong, Young Mee Bae Parasitology Research.2009; 104(5): 1011. CrossRef
Prevalence of clonorchiasis in patients with gastrointestinal disease: A Korean nationwide multicenter survey Ho Gak Kim, Jimin Han, Myung-Hwan Kim, Kyu Hyun Cho, Im Hee Shin, Gwang Ha Kim, Jae Seon Kim, Jin Bong Kim, Tae Nyeun Kim, Tae Hyeon Kim, Tae Hyo Kim, Jae Woo Kim, Ji Kon Ryu, Young-Soo Moon, Jong Ho Moon, Sung Jae Park, Chan Guk Park, Sung-Jo Bang, Chang World Journal of Gastroenterology.2009; 15(1): 86. CrossRef
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Clonorchis sinensis-Associated Cholangiocarcinoma: A Case Report and Review of the Literature Georgios I. Papachristou, Karen E. Schoedel, Ramesh Ramanathan, Mordechai Rabinovitz Digestive Diseases and Sciences.2005; 50(11): 2159. CrossRef
Phenotypic diversity of intrahepatic and extrahepatic cholangiocarcinoma on aspiration cytology and core needle biopsy Humera B. Chaudhary, Punam Bhanot, Roberto Logroño Cancer.2005; 105(4): 220. CrossRef
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Clonorchiasis: an update H.-J. Rim Journal of Helminthology.2005; 79(3): 269. CrossRef
Clonorchiasis and Cholangiocarcinoma: Etiologic Relationship and Imaging Diagnosis Byung Ihn Choi, Joon Koo Han, Sung Tae Hong, Kyoung Ho Lee Clinical Microbiology Reviews.2004; 17(3): 540. CrossRef
Use of a recombinant Clonorchis sinensis pore-forming peptide, clonorin, for serological diagnosis of clonorchiasis Ji-Yun Lee, Tae Yun Kim, Xiao-Xian Gan, Shin-Yong Kang, Sung-Jong Hong Parasitology International.2003; 52(2): 175. CrossRef
Hemolytic activity and developmental expression of pore-forming peptide, clonorin Ji-Yun Lee, Pyo-Yun Cho, Tae Yun Kim, Shin-Yong Kang, Kye-Yong Song, Sung-Jong Hong Biochemical and Biophysical Research Communications.2002; 296(5): 1238. CrossRef
Trematodes of the family Opisthorchiidae: a minireview Sandie King, Tomáš Scholz The Korean Journal of Parasitology.2001; 39(3): 209. CrossRef
Infectivity and Pathological Changes in Murine Clonorchiasis: Comparison in Immunocompetent and Immunodeficient Mice. Byung-II YOON, Yang-Kyu CHOI, Dae-Yong KIM, Byung-Hwa HYUN, Kyoung-Hwan JOO, Han-Jong RIM, Jae-Hyun LEE Journal of Veterinary Medical Science.2001; 63(4): 421. CrossRef
Molecular cloning and characterization of a mu-class glutathione S-transferase from Clonorchis sinensis Sung-Jong Hong, Ji-Yun Lee, Dong-Hwa Lee, Woon-Mok Sohn, Seung-Yull Cho Molecular and Biochemical Parasitology.2001; 115(1): 69. CrossRef
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Biliary Papillary Hyperplasia With Clonorchiasis Resembling Cholangiocarcinoma K H Kim, C D Kim, H S Lee, S J Lee, Y T Jeen, H J Chun, C W Song, S W Lee, S H Um, J H Choi, H S Ryu, J H Hyun American Journal of Gastroenterology.1999; 94(2): 514. CrossRef