Parasites, Hosts and Diseases

"nematode"

Review

Paleoparasitology research on ancient helminth eggs and larvae in the Republic of Korea: Jong-Yil Chai, Min Seo, Dong Hoon Shin; Parasites Hosts Dis 2023;61(4):345-387.
Published online November 28, 2023; DOI: https://doi.org/10.3347/PHD.23085

Abstract
PDF

Paleoparasitology is a discipline that applies existing conventional and molecular techniques to study parasites found in ancient ruins. This review focuses on the history of the discovery of parasites (mostly helminth eggs and larvae) in archaeological soil samples and mummies in Korea from the Three Kingdoms Period to the Joseon Dynasty (100 BCE-1910 CE). We also briefly review important milestones in global paleoparasitology. The helminth species reported so far in Korea included Ascaris lumbricoides, Trichuris trichiura, Strongyloides stercoralis (larva), Trichostrongylus sp. (larva), Paracapillaria philippinensis (syn. Capillaria philippinensis), Enterobius vermicularis, Fasciola hepatica, dicrocoeliids, Paragonimus westermani, Clonorchis sinensis, Metagonimus yokogawai, Pygidiopsis summa, Gymnophalloides seoi, Isthmiophora hortensis, Dibothriocephalus nihonkaiensis (syn. Diphyllobothrium nihonkaiense), and Taenia spp. tapeworms. The findings obtained by Korean paleoparasitologists/archaeologists have brought about deep insight into the status of helminthic infections in Korea’s past populations. Continued paleoparasitological research is essential for further understanding of ancient parasites and parasitic diseases in Korea.

Citations

Citations to this article as recorded by

Imported parasitic diseases in the Republic of Korea: status and issues
Jong-Yil Chai
Journal of the Korean Medical Association.2025; 68(1): 52. CrossRef

7,117 View
224 Download
1 Web of Science
Crossref

Brief Communications

Standard- and large-sized eggs of Trichuris trichiura in the feces of schoolchildren in the Yangon Region, Myanmar: Morphological and molecular analyses: Seungwan Ryoo, Bong-Kwang Jung, Sooji Hong, Hyejoo Shin, Hyemi Song, Hyun-Seung Kim, Jin-Youp Ryu, Woon-Mok Sohn, Sung-Jong Hong, Thi Thi Htoon, Htay Htay Tin, Jong-Yil Chai; Parasites Hosts Dis 2023;61(3):317-324.
Published online August 21, 2023; DOI: https://doi.org/10.3347/PHD.23059

Standard- and large-sized eggs of Trichuris trichiura were found in the feces of schoolchildren in Yangon, Myanmar during epidemiological surveys and mass deworming with albendazole in 2017-2019. The standard-sized eggs were identified as those of T. trichiura, but it was necessary to exclude the possibility of the large-sized eggs belonging to Trichuris vulpis, a dog whipworm. We conducted morphological and molecular studies to determine the species of the 2 types of Trichuris eggs. Individual eggs of both sizes were isolated from Kato-Katz fecal smears (n=20) and mechanically destroyed using a 23G injection needle. Nuclear DNA was extracted, and the 18S rRNA region was sequenced in 15 standard-sized eggs and 15 large-sized eggs. The average size of standard-sized eggs (T. trichiura) was 55.2×26.1 μm (range: 51.7-57.6×21.3-28.0 μm; n=97), whereas the size of large-sized eggs was 69.3×32.0 μm (range: 65.1-76.4×30.1-34.5 μm; n=20), slightly smaller than the known size of T. vulpis. Regarding standard-sized eggs, the 18S rRNA nucleotide sequences exhibited 100% homology with T. trichiura deposited in GenBank and 88.6-90.5% homology with T. vulpis. Regarding large-sized eggs, the nucleotide sequences showed 99.8-100% homology with T. trichiura in GenBank and 89.6-90.7% homology with T. vulpis. Both standard- and large-sized eggs of Trichuris spp. found in Myanmar schoolchildren during 2017-2019 were morphologically and molecularly confirmed to belong to T. trichiura. The conversion of eggs from smaller to large sizes might be due to anthelmintic treatments with albendazole.

Citations

Citations to this article as recorded by

Paleoparasitology research on ancient helminth eggs and larvae in the Republic of Korea
Jong-Yil Chai, Min Seo, Dong Hoon Shin
Parasites, Hosts and Diseases.2023; 61(4): 345. CrossRef

8,990 View
101 Download
2 Web of Science
Crossref

Distribution of Gastrointestinal Parasitic Infection in Domestic Pigs in the Republic of Korea: Nationwide Survey from 2020-2021: Subin Lee, Badriah Alkathiri, Dongmi Kwak, Sang-Myeong Lee, Wan-Kyu Lee, Jae-Won Byun, Seung-Hun Lee; Korean J Parasitol 2022;60(3):207-211.
Published online June 30, 2022; DOI: https://doi.org/10.3347/kjp.2022.60.3.207

This study aimed to examine the distribution of gastrointestinal parasitic infections in domestic pigs in the Republic of Korea. From May 2020 to October 2021, 364 pig fecal samples were collected from 75 farms in 7 Provinces and microscopically examined. A total of 170 (46.7%) pigs were infected with at least one of the following parasites: Balantioides coli, strongyles, Ascaris suum, Trichuris suis, and coccidia. By parasite species, B. coli, strongyles, A. suum, T. suis, and coccidia oocysts or eggs were detected in 144 (39.6%), 24 (6.6%), 14 (3.8%), 4 (1.1%), and 1 (0.3%) samples, respectively. One hundred fifty-four, 15, and 1 cases showed single, double, and triple infections, respectively. Of the swine fecal samples from 75 farms, 69 specimens (92.0%) were infected with 1 or more parasites. All surveyed farms across the country exhibited a positive rate of over 30%, among which the highest positive rate was 65.0% in Chungcheongnam-do, and Jeollabuk-do was followed by 61.9%. Winter showed a statistically lower prevalence than other seasons. This study showed that gastrointestinal parasites are prevalent in pigs in Korea, although the diversity of parasites is low.

Citations

Citations to this article as recorded by

Molecular identification and diversity of gastrointestinal apicomplexan protozoa in pigs in the Republic of Korea
Subin Lee, Sang-Hyup Lee, Badriah Alkathiri, Kyung-Duk Min, Dong Hyeon Kwon, Mi-Hye Hwang, Gyu-Tae Jeon, Bok Kyung Ku, Jae-Won Byun, Seung-Hun Lee
Scientific Reports.2025;[Epub] CrossRef
Gastrointestinal parasites in pigs in Brazil: prevalence, risk factors, diagnosis, and extension activities
Camila Souza Carvalho Class, Renan de Souza Ferreira, Ana Luiza Soares de Araujo, Ingrid da Silva Reis, Breno Torres da Silva, Fabiana Batalha Knackfuss, Laís Lisboa Corrêa, José Arcínio de Assis, Marcelo José Milagres de Almeida, Daniel de Castro Trindad
Parasitology Research.2025;[Epub] CrossRef
Integrative use of conventional and DNA metabarcoding methods reveals high diversity, prevalence and intensity of gastrointestinal parasites in pigs from Victoria, Australia
Ghazanfar Abbas, Yuet On Lee, Hannah Mitchell, Abdul Ghafar, Mark A. Stevenson, Charles G. Gauci, Leah G. Starick, Regina M. Fogarty, Bernie Gleeson, Dianne E. Phillips, Tao Wang, Robin B. Gasser, Abdul Jabbar
Research in Veterinary Science.2025; 196: 105902. CrossRef
Prevalence and diversity of gastrointestinal parasites on pig farms in Kalasin Province, Thailand
Sirikanda Thanasuwan, Supawadee Piratae, Keattipong Thaowandee, Chalothon Amporn
Veterinary World.2024; : 273. CrossRef
Comparative Analysis of Ascaris suum and Macracanthorhynchus hirudinaceus Infections in Free-Ranging and Captive Wild Boars (Sus scrofa) in Hungary
Csaba Farkas, Alexandra Juhász, Balázs Fekete, Borisz Egri
Animals.2024; 14(6): 932. CrossRef
Parasites burden in peri-urban free-roaming pigs in Gert Sibande District Municipality, Mpumalanga Province, South Africa
P Munzhelele, NPS Sibeko, JW Oguttu, CA Mbajiorgu, FO Fasina
Journal of the South African Veterinary Association.2024; 95(1): 55. CrossRef
Prevalence of intestinal parasites in humans and domestic animals in Jirel community, Dolakha, Nepal
Pitambar Dhakal, Medhavi Dhakal, Dipa Dhakal, Pramita Shakya, Barsha Singh, Rabina Gupta Kalwar, Rekha Shahi, Sophiya Pandey, Darwin Niraula, Anita Karki, Mukesh Kumar Mahato, Semsal Tamang, Basanti Chhetri, Muna Thapa, Rameshwor Parajuli, Janak Raj Subed
Journal of Family Medicine and Primary Care.2024; 13(8): 3408. CrossRef

5,527 View
217 Download
8 Web of Science
Crossref

Original Article

Electrophysiological Properties of Ion Channels in Ascaris suum Tissue Incorporated into Planar Lipid Bilayers: Kwon Moo Park, Sun-Don Kim, Jin Bong Park, Sung-Jong Hong, Pan Dong Ryu; Korean J Parasitol 2021;59(4):329-339.
Published online August 18, 2021; DOI: https://doi.org/10.3347/kjp.2021.59.4.329

Abstract
PDF

Ion channels are important targets of anthelmintic agents. In this study, we identified 3 types of ion channels in Ascaris suum tissue incorporated into planar lipid bilayers using an electrophysiological technique. The most frequent channel was a large-conductance cation channel (209 pS), which accounted for 64.5% of channels incorporated (n=60). Its open-state probability (P_o) was ~0.3 in the voltage range of –60~+60 mV. A substate was observed at 55% of the main-state. The permeability ratio of Cl^- to K⁺ (P_Cl/P_K) was ~0.5 and P_Na/P_K was 0.81 in both states. Another type of cation channel was recorded in 7.5% of channels incorporated (n=7) and discriminated from the large-conductance cation channel by its smaller conductance (55.3 pS). Its Po was low at all voltages tested (~0.1). The third type was an anion channel recorded in 27.9% of channels incorporated (n=26). Its conductance was 39.0 pS and P_Cl/P_K was 8.6±0.8. P_o was ~1.0 at all tested potentials. In summary, we identified 2 types of cation and 1 type of anion channels in Ascaris suum. Gating of these channels did not much vary with voltage and their ionic selectivity is rather low. Their molecular nature, functions, and potentials as anthelmintic drug targets remain to be studied further.

4,660 View
102 Download

Mini Reviews

Albendazole and Mebendazole as Anti-Parasitic and Anti-Cancer Agents: an Update: Jong-Yil Chai, Bong-Kwang Jung, Sung-Jong Hong; Korean J Parasitol 2021;59(3):189-225.
Published online June 21, 2021; DOI: https://doi.org/10.3347/kjp.2021.59.3.189

Abstract
PDF

The use of albendazole and mebendazole, i.e., benzimidazole broad-spectrum anthelmintics, in treatment of parasitic infections, as well as cancers, is briefly reviewed. These drugs are known to block the microtubule systems of parasites and mammalian cells leading to inhibition of glucose uptake and transport and finally cell death. Eventually they exhibit ovicidal, larvicidal, and vermicidal effects on parasites, and tumoricidal effects on hosts. Albendazole and mebendazole are most frequently prescribed for treatment of intestinal nematode infections (ascariasis, hookworm infections, trichuriasis, strongyloidiasis, and enterobiasis) and can also be used for intestinal tapeworm infections (taeniases and hymenolepiasis). However, these drugs also exhibit considerable therapeutic effects against tissue nematode/cestode infections (visceral, ocular, neural, and cutaneous larva migrans, anisakiasis, trichinosis, hepatic and intestinal capillariasis, angiostrongyliasis, gnathostomiasis, gongylonemiasis, thelaziasis, dracunculiasis, cerebral and subcutaneous cysticercosis, and echinococcosis). Albendazole is also used for treatment of filarial infections (lymphatic filariasis, onchocerciasis, loiasis, mansonellosis, and dirofilariasis) alone or in combination with other drugs, such as ivermectin or diethylcarbamazine. Albendazole was tried even for treatment of trematode (fascioliasis, clonorchiasis, opisthorchiasis, and intestinal fluke infections) and protozoan infections (giardiasis, vaginal trichomoniasis, cryptosporidiosis, and microsporidiosis). These drugs are generally safe with few side effects; however, when they are used for prolonged time (>14-28 days) or even only 1 time, liver toxicity and other side reactions may occur. In hookworms, Trichuris trichiura, possibly Ascaris lumbricoides, Wuchereria bancrofti, and Giardia sp., there are emerging issues of drug resistance. It is of particular note that albendazole and mebendazole have been repositioned as promising anti-cancer drugs. These drugs have been shown to be active in vitro and in vivo (animals) against liver, lung, ovary, prostate, colorectal, breast, head and neck cancers, and melanoma. Two clinical reports for albendazole and 2 case reports for mebendazole have revealed promising effects of these drugs in human patients having variable types of cancers. However, because of the toxicity of albendazole, for example, neutropenia due to myelosuppression, if high doses are used for a prolonged time, mebendazole is currently more popularly used than albendazole in anti-cancer clinical trials.

Citations

Citations to this article as recorded by

Synthesis, structural characterization, and biological assessment of iron, nickel, and manganese complexes with albendazole-salicylic acid ligand: a combined DFT, in vitro, and in silico study
Mohammed A.O. Basubaih, Nahla S Zidan, Hany M.Abd El-Lateef, Mai M. Khalaf, Aly Abdou
Journal of Molecular Structure.2026; 1352: 144411. CrossRef
Ecotoxicological risk and environmental assessment of mebendazole: A comprehensive study using freshwater snails as non-target species
Dinghao Li, Ji Wu, Yunyi Hu, Zifeng Zhu, Yao Liao, Yuheng Liu, Yun Huang, Peiying Peng, Du Gao, Zhongdao Wu, Chuan Bai, Xi Sun, Datao Lin
Journal of Hazardous Materials.2026; 501: 140652. CrossRef
Quinolinyl-appended chalcones as promising antiproliferative and trypanocidal agents: Synthesis, biological profiling, and further transformation into novel benzo[f]pyrazolo[5,1-a][2,7]naphthyridine and quinoline-pyrido[2,3-d]pyrimidin-2,4-dione hybrids
Diego Rodríguez, Elizabeth Gómez, Mauricio Moncada-Basualto, Esteban Rocha-Valderrama, Elena Stashenko, Justo Cobo, Alirio Palma
Bioorganic Chemistry.2026; 168: 109306. CrossRef
Resistance to benzimidazole in South India: Polymorphic variants in the β-tubulin gene of Ascaris lumbricoides and Necator americanus
Revathi Ulaganeethi, Nonika Rajkumari, Palanivel Chinnakali, Priyanka Jasmine, Gowri Dorairajan, Ganesh Kumar Saya
One Health Bulletin.2025;[Epub] CrossRef
Doxycycline cotherapy with albendazole relieves neural function damage in C57BL/6 and BALB/c mice infected with Angiostrongylus cantonensis
Eny Sofiyatun, Kuang-Yao Chen, Chih-Jen Chou, Hsin-Chia Lee, Yi-An Day, Pei-Jui Chiang, Cheng-Hsun Chiu, Wei-June Chen, Kai-Yuan Jhan, Lian-Chen Wang
Biomedical Journal.2025; 48(1): 100727. CrossRef
Albendazole nanosuspension coated granules for the rapid localized release and treatment of colorectal cancer
Yi Guo, Henis J. Patel, Akanksha S. Patel, Emilio Squillante, Ketan Patel
Colloids and Surfaces B: Biointerfaces.2025; 245: 114320. CrossRef
Nematicidal Potentiality of Four Marine Molluscans' Defensive Secretions From the Red Sea Against Syphacia obvelata (Nematoda: Oxyuridae) In Vitro
Nahla A. Radwan, Aalaa I. Atlam, Asmaa R. Abdel‐ Malek, Alaa Y. Moustafa
Journal of Experimental Zoology Part A: Ecological and Integrative Physiology.2025; 343(2): 149. CrossRef
Efficacy of nitazoxanide, ivermectin and albendazole in treatment of cryptosporidiosis in immunosuppressed mice
Basma M. Elmansory, Rabab Sayed Zalat, Eman Khaled, Noha Madbouly Taha
Journal of Parasitic Diseases.2025; 49(2): 343. CrossRef
Evaluation of the prophylactic and therapeutic effects of selenium and vitamin E on the muscular phase of experimental Trichinella spiralis infection in mice
Amira Mamdouh Mohamed, Amany Mohammed Hegab, Samar Ibrahim Ismail Amer, Rabab Sayed Zalat, Eman Yassien Shoeib, Iman Raafat Abdel-Shafi
Journal of Parasitic Diseases.2025; 49(2): 378. CrossRef
Repurposing of Amiodarone for treatment of muscle phase of experimental Trichinellosis spiralis
Gehad A. Abdelhamid, Amany A. Abdel-Aal, Manal Badawi, Mennat-Elrahman A. Fahmy, Asmaa R. Abd-Alghany
Journal of Parasitic Diseases.2025; 49(2): 419. CrossRef
A combined treatment regimen for Trichuris rhinopiptheroxella infection in Rhinopithecus roxellana in southern China
Zhengjiu Ren, Jinzhi Lu, Tianyou Zhang, Lihua Xiao, Peng Zhang, Guixin Dong, Yaoyu Feng, Dongjuan Yuan
International Journal for Parasitology: Parasites and Wildlife.2025; 26: 101036. CrossRef
Ascaris lumbricoides a rare cause gastric perforation: a case report and brief literature review
Tian-Hao Xie, Yan Fu, Xiang-Xiang Ren, Xin-Li Sun, Qiang Wang, Qian Sun
Frontiers in Medicine.2025;[Epub] CrossRef
Tea Saponins: a Novel Stabilizer for Enhancing the Oral Bioavailability of Albendazole Nanocrystals
Sumin Lan, Kexi Chen, Liqiang Feng, Panle Sima, Xiaoyao Ji, Feihua Wu, Yining Lin
AAPS PharmSciTech.2025;[Epub] CrossRef
Cystic echinococcosis of the liver
Hassan Aziz, Peyton Seda, Yashant Aswani, Matthew D. Gosse, Aparna Joshi Krishnakumari, Timothy M. Pawlik
Journal of Gastrointestinal Surgery.2025; 29(3): 101974. CrossRef
Ascaris lumbricoides Emerging from a PleurX Draining Catheter: An Unexpected Diagnosis
Hasan Arafat, Hamza A Abdul-Hafez, Ali Sabateen
Clinical Medicine Insights: Case Reports.2025;[Epub] CrossRef
Human dirofilariasis – A potentially significant nematode zoonosis in an era of climate change
Stefan Momčilović, Andriana Jovanović, Robin B. Gasser
Journal of Infection.2025; 90(4): 106460. CrossRef
In Vitro Evaluation of Esters of Quinoxaline-1,4-di-N-oxide Derivatives as New Antitaeniasis Agents and Their Inhibitory Activity Against Triosephosphate Isomerase
Francisca Palomares-Alonso, Alonzo González-González, Alma D. Paz-González, Eyra Ortiz-Pérez, Ana Verónica Martínez-Vázquez, Itzhel García-Torres, Gabriel López-Velázquez, Helgi Jung-Cook, Gildardo Rivera
Pharmaceuticals.2025; 18(3): 406. CrossRef
Current perspectives in the epidemiology and control of lymphatic filariasis
Dziedzom K. de Souza, Moses J. Bockarie, Louisa A. Messenger
Clinical Microbiology Reviews.2025;[Epub] CrossRef
Harmine derivative H-2-168 induces the death of Echinococcus granulosus by regulating mitochondrial fusion and fission
Yuehong Gong, Meiling Zhao, Meichi Pan, Yicong Zhao, Junpeng Liu, Hao Wen, Jianhua Wang
Pharmaceutical Biology.2025; 63(1): 188. CrossRef
Sublethal concentrations of anthelmintic drugs (albendazole and levanide) induce insecticidal effects and midgut ultrastructural changes in Spodoptera frugiperda (Lepidoptera: Noctuidae)
Marian Malak, Ashraf M. Abdel-Moneim, Mourad Shonouda
Journal of Asia-Pacific Entomology.2025; 28(2): 102407. CrossRef
Multi-omics insights into the response of the gut microbiota and metabolites to albendazole deworming in captive Rhinopithecus brelichi
Xinxi Qin, Jincheng Han, Li Xi, Longfei Zhao, Zhiqiang Li, Yanyan Cui, Junfang Hao
Frontiers in Microbiology.2025;[Epub] CrossRef
Metformin innovative repurposing as anti-parasitic drug in the treatment of murine trichinosis
Y.S. Mahmoud, E.S. El-Wakil, M.H. Elsayad, G.A.M Khodear, A. Kazem, H. Elhadad
Journal of Helminthology.2025;[Epub] CrossRef
Treatment of loiasis: a review of clinical management recommendations
Dorothea Ekoka Mbassi, Rike Dreeßen, Rella Zoleko Manego, Saskia Dede Davi, Tamara Nordmann, Johannes Mischlinger, Michael Ramharter
Infectious Diseases of Poverty.2025;[Epub] CrossRef
Silibinin enhanced the efficacy of albendazole in treating the muscular phase of experimental trichinellosis
Mennat-Elrahman A. Fahmy, Marwa Esmat, Manal Badawi, Iman R. Abdel Shafi
Tropical Animal Health and Production.2025;[Epub] CrossRef
Alendronate repositioning as potential anti-parasitic agent targeting Trichinella spiralis inorganic pyrophosphatase, in vitro supported molecular docking and molecular dynamics simulation study
Marmar A. Hanafy, Doaa A. Nassar, Fatima M. Zahran, Magdy M. D. Mohammed
BMC Chemistry.2025;[Epub] CrossRef
Repurposing of Mebendazole as an Anticancer Agent: A Review
Vikram V. Nimbalkar, Sakshi A. Bhongal, Nikita R. Dhage, Ganesh D. Barkade
Research Journal of Pharmacy and Technology.2025; : 1619. CrossRef
Selenium Mediated Cyclization Reaction of Isonitriles with o-Aminophenols to Synthesize 2-Aminobenzoxazoles
Zheng Wang, Yuqin Lan, Zhiyi Zhou, Yingzi Tan, Zongcheng Wang
Chinese Journal of Organic Chemistry.2025; 45(4): 1379. CrossRef
Metal-Free and Scalable Sulfoxide Reduction through the Couple (COCl)2/Et3SiH: Synthesis of Albendazole Hydrochloride
Camilo Morales-Manrique, Salima Gutierrez-Acevedo, Laura Adarve-Cardona, Alexander Garay-Talero, Diego Gamba-Sánchez
Synthesis.2025; 57(12): 1936. CrossRef
Diagnosis, management and prevention of loiasis: guideline of the German Society for Tropical Medicine, Travel Medicine, and Global Health (DTG)
Michael Ramharter, Stefan Schlabe, Marc P. Hübner, Pia Michelitsch, Florian Kurth, Sabine Bélard, Tamara Nordmann, Saskia Dede Davi
Infection.2025; 53(3): 851. CrossRef
Cassia alata: Helminth and Bacteria Fighter
Rabab E. Elshershaby, Mohamed A. Dkhil, Yasser Dar, Rewaida Abdel-Gaber, Denis Delic, Ibrahim B. Helal
Combinatorial Chemistry & High Throughput Screening.2025; 28(8): 1301. CrossRef
Identification of Aspartate Aminotransferase FocAST2 as a Novel Target of Albendazole in Fusarium oxysporum f. sp. cubense TR4
Yushan Liu, Siwen Liu, Cheng Peng, Huoqing Huang, Wei Zhang, Yile Huo, Ganjun Yi, Weiqing Zeng, Chunyu Li
Journal of Agricultural and Food Chemistry.2025; 73(26): 16180. CrossRef
Synthesis and In Vitro Biological Studies of Heterocyclic Benzimidazole Derivatives as Potential Therapeutics for Trichinellosis
Kameliya Anichina, Galya Popova-Daskalova, Dimitar Vuchev, Maya Guncheva, Denitsa Yancheva, Nikolai Georgiev
Applied Sciences.2025; 15(12): 6758. CrossRef
Piperazine Use in a Case of Recurrent Entero-biliary Ascariasis
Manoj Kumar Sundarka, Archana Sundarka
Journal of The Association of Physicians of India.2025; 73(1): e27. CrossRef
Synthesis and SARs of benzimidazoles: insights into antimicrobial innovation (2018–2024)
Ahmed A. Ibrahim, Eman G. Said, Asmaa M. AboulMagd, Noha H. Amin, Hamdy M. Abdel-Rahman
RSC Advances.2025; 15(27): 22097. CrossRef
Lack of knowledge of stakeholders in the pork value chain: Considerations for transmission and control of Taenia solium and Toxoplasma gondii in Burundi
Salvator Minani, Jean-Bosco Ntirandekura, Koen Peeters Grietens, Anastasie Gasogo, Sarah Gabriël, Chiara Trevisan, Adetayo Olorunlana
PLOS One.2025; 20(7): e0326238. CrossRef
An Overview on Antifilarial Efficacy of Heterocyclic Motifs Encompassing Synthetic Strategies, SAR and Commercialized Medications
Sumit Tahlan, Sucheta Singh, Kailash C. Pandey
Current Topics in Medicinal Chemistry.2025; 25(11): 1303. CrossRef
Efficacy of levamisole-loaded nanoparticles in the treatment of Trichinella spiralis infection in mice
F.A. Nasr, A.A. Qurtam
Arquivo Brasileiro de Medicina Veterinária e Zootecnia.2025;[Epub] CrossRef
Pharmacological investigation on the antiparasitic properties of Alstonia scholaris focussing on the antiplasmodial and anticestodal uses in the Mizo traditional medicine of India
Lalngaihmanawmi, Pawi Bawitlung Lalthanpuii, Bawitlung Lalruatfela, Lalnundanga, Kholhring Lalchhandama
Vegetos.2025;[Epub] CrossRef
New heterogeneous Bi17V0.6Nb2.4-xPxO33 fluorite catalysts for the synthesis of benzimidazole derivatives
Saloua Baddou, Youssef Merroun, Soumya Ferraa, Soukaina Chehab, Rachida Ghailane, Abdelaziz Souizi, Taoufiq Guedira
Research on Chemical Intermediates.2025; 51(9): 4849. CrossRef
A Rare Case of Isolated Psoas Muscle Echinococcal Cyst
Yuan Lu, Liuyang Zhan, Huwei Jiang, Xiaofeng Li, Chao Jiang
Cureus.2025;[Epub] CrossRef
Critical dysregulated signaling pathways in drug resistance: highlighting the repositioning of mebendazole for cancer therapy
Amin Aliabadi, Seyed Zachariah Moradi, Sadaf Abdian, Sajad Fakhri, Javier Echeverría
Frontiers in Pharmacology.2025;[Epub] CrossRef
Effects of Lucilia sericata Larval Secretion on Echinococcus granulosus
Feza İrem Aldı, Kıymet Tabakçıoglu, Erdal Polat, Nermin Şakru
Turkish Journal of Parasitology.2025;[Epub] CrossRef
Metal-organic frameworks (MOFs): Redefining antiparasitic drug delivery
Aracely López-Monteon, Rodolfo Peña-Rodríguez, José María Rivera-Villanueva, Anahí Sosa-Arróniz, Lidia E. Chiñas-Rojas, Angel Ramos-Ligonio
Acta Tropica.2025; 269: 107764. CrossRef
Surgery for Liver Cystic Echinococcosis: Risk Factors Related to the Risk of Complex Biliary Fistula and Hepatic Recurrence. Results of a Long‐Term Cohort Study
Marina Vila‐Tura, Emilio Ramos, David Leiva, Kristel Mils, Josefina López‐Domínguez, Oriana Barrios, Laura Lladó
World Journal of Surgery.2025; 49(9): 2409. CrossRef
Effectiveness Therapy to Eliminate Parasite in Cattle at Teaching Factory Polytechnic State of Lampung
Vindo Rossy Pertiwi, Dwi Desmiyeni Putri, Fadli Syihabbudin
Journal of Applied Veterinary Science And Technology.2025; 6(1): 85. CrossRef
MEBENDAZOLE LOADED NANOSPONGES CAPSULES FOR TREATMENT OF WORM INFECTIONS
Manisha S. Karpe, Amit S. Ghosh
INDIAN DRUGS.2025; 62(07): 18. CrossRef
Protective and therapeutic effects of Lactobacillus brevis PQ214320 and Bacillus subtilis PQ198038 Against experimental Trichinella Infection
Eman E. El Shanawany, Rania Abdel-Razik, Amany Ebrahim Nofal, Rabab S. Zalat, Faten Abouelmagd, Fernando Lopes
PLOS Neglected Tropical Diseases.2025; 19(8): e0013331. CrossRef
NanoDSF Screening for Anti-tubulin Agents Uncovers New Structure–Activity Insights
Viktoriia Baksheeva, Romain La Rocca, Diane Allegro, Carine Derviaux, Eddy Pasquier, Philippe Roche, Xavier Morelli, François Devred, Andrey V. Golovin, Philipp O. Tsvetkov
Journal of Medicinal Chemistry.2025; 68(16): 17485. CrossRef
Exploring glutamate-gated chloride channels in cancer cells: A narrative review on a hypothetical mechanism underpinning the anticancer effects of antiparasitic drugs
M. M. Akl, A. Ahmed
Сибирский научный медицинский журнал.2025; 45(4): 6. CrossRef
Amorphization of Albendazole Using Organic Acid-based Solid Dispersions for Improved Dissolution: A Solvent-free Approach
Nilesh Jambukiya, Kiran Dudhat, Sunny shah, Chetan Borkhataria, Trupesh Pethani, Ramesh Parmar, Viral Shah, Gaurav Sanghvi, Mori Dhaval
AAPS PharmSciTech.2025;[Epub] CrossRef
Small bowel perforation by Anisakis infection due to raw fish consumption: a rare entity to consider
V. Fleury, G. Liegeois, M. Benkabouche, S. Vora, M. Pannatier, P. Buono, M. Genevay, L. Buhler
European Journal of Clinical Microbiology & Infectious Diseases.2025;[Epub] CrossRef
The Road to Precision Nanomedicine: An Insight on Drug Repurposing and Advances in Nanoformulations for Treatment of Cancer
Yasmina Elmahboub, Rofida Albash, Sadek Ahmed, Salwa Salah
AAPS PharmSciTech.2025;[Epub] CrossRef
Concise Synthesis of Monocarbamate-Cyclohexanetriacetate from Allylic Bis-Carbamate
L. Kelebekli
Russian Journal of General Chemistry.2025; 95(9): 2528. CrossRef
[VIVO]/[VVO]/[VVO2] Complexes of Trinucleating Ligands: Synthesis, Characterization, Structural Evidence for a Hexanuclear Complex, and Their Catalytic Potential for the Synthesis of Pyrimido[1,2-a]benzimidazoles
Mannar R. Maurya, Devesh Singh, Sonu Kumar, Puneet Gupta, Fernando Avecilla
Inorganic Chemistry.2025; 64(41): 20747. CrossRef
Novel Oral papaya-based preventive and therapeutic vaccine for controlling different zoonotic Taeniid parasites: Current advances
Marisela Hernández, Anabel Ortiz Caltempa, Nelly Villalobos, María Celina Elisondo, Cynthia Guzmán, Juan A. Hernández-Aceves, Liliana Aguilar, Ivan Flores-Pérez, José Juan Martínez, Sahara D. Elguea Zarate, Maria Jesús Perteguer Prieto, Gabriela Meneses,
Vaccine.2025; 66: 127818. CrossRef
Similar patterns of benzimidazole resistance alleles in ovine gastrointestinal nematodes from Western Canada and Eastern United States supports their shared origins and subsequent spread
Camila Queiroz, Michel Levy, Russell Avramenko, Rebecca Chen, Michaela Seal, Elizabeth Redman, Anne Zajac, John Stuart Gilleard
International Journal for Parasitology: Drugs and Drug Resistance.2025; 29: 100620. CrossRef
Proteomic and Phosphoproteomic Analysis of Adult Taenia saginata Revealed the Potential Importance of Cytoskeleton-Related Proteins
Kang Liu, Kaijuan Wu, Xiaohua Liu, Jing Xie, Yixiao Wang, Chandara Ngim, Die Hu, Yangfan Xiao, Zheng Wang, Yisong Liu, Wei Liu, Liping Jiang
Journal of Proteome Research.2025; 24(11): 5727. CrossRef
A 5‐Year Survey on Multiple Targeted Benzimidazole Hybrids
Ayşen Işik, Ulviye Acar Çevik
Chemistry & Biodiversity.2025;[Epub] CrossRef
Reação Cutânea Grave Em Pediatria: Síndrome De Stevens-Johnson Associada Ao Uso De Albendazol
Juliana Azevedo Raphael Leite, Priscilla Guerra Moura
Journal of Medical Residency Review.2025; 4(00): e098. CrossRef
Spontaneous exovesiculation of a hepatic hydatid cyst with an intact vesicle: A rare intraoperative finding
Hazem Alouani, Ghazi Lâamiri, Khadija Yaich, Houda Gazzah, Mahdi Bouassida, Hassen Touinsi
IDCases.2025; 42: e02439. CrossRef
DNA‐Binding Potential of Benzo[h]Quinolines: A Combined Molecular Docking and ADMET Approach
Uzma Khan, Souvik Sur, Hemlata Nimesh
Macromolecular Symposia.2025;[Epub] CrossRef
Ubenimex combined with Albendazole for the treatment of Echinococcus multilocularis-induced alveolar echinococcosis in mice
Zhen Zhou, Meiduo Huayu, Yalin Mu, Feng Tang, Ri-Li Ge
Frontiers in Veterinary Science.2024;[Epub] CrossRef
In-silico design, pharmacophore-based screening, and molecular docking studies reveal that benzimidazole-1,2,3-triazole hybrids as novel EGFR inhibitors targeting lung cancer
Sunil Kumar, Iqra Ali, Faheem Abbas, Anurag Rana, Sadanand Pandey, Manoj Garg, Deepak Kumar
Journal of Biomolecular Structure and Dynamics.2024; 42(18): 9416. CrossRef
Ocular Toxocariasis in Adult Caucasian Patients: Clinical Presentations and Treatment Outcomes
Marie-Gwenola Desurmont, Alexandre Bourdin, Luc Paris, Adélaide Toutée, Emilien Faudi, Christine Fardeau, Bahram Bodaghi, Sara Touhami
Ocular Immunology and Inflammation.2024; 32(8): 1741. CrossRef
Mebendazolium mesylate anhydride salt: rational design based on supramolecular assembly, synthesis, and solid-state characterization
Eduardo L. Gutiérrez, Agustín A. Godoy, Elena V. Brusau, Daniel Vega, Griselda E. Narda, Sebastián Suárez, Florencia Di Salvo
RSC Advances.2024; 14(1): 181. CrossRef
Amebicides against Acanthamoeba castellanii: The Impact of Organism Models Used in Amebicide Assays
Leonardo Fernandes Geres, Elena Sartori, João Marcos dos Santos Neves, Danilo Ciccone Miguel, Selma Giorgio
Parasitologia.2024; 4(1): 15. CrossRef
Clonorchiasis and opisthorchiasis: epidemiology, transmission, clinical features, morbidity, diagnosis, treatment, and control
Men-Bao Qian, Jennifer Keiser, Jürg Utzinger, Xiao-Nong Zhou, Graeme N. Forrest
Clinical Microbiology Reviews.2024;[Epub] CrossRef
Photochemical reactions as synthetic tool for pharmaceutical industries
Shehla Khalid, Muhammad Bilal, Nasir Rasool, Muhammad Imran
Chinese Chemical Letters.2024; 35(9): 109498. CrossRef
Single nucleotide polymorphisms in the β-tubulin gene family of Ascaris lumbricoides and their potential role in benzimidazole resistance: a systematic review
Teniel Ramkhelawan, Pragalathan Naidoo, Zilungile L. Mkhize-Kwitshana
Frontiers in Tropical Diseases.2024;[Epub] CrossRef
Combinations of the azaquinazoline anti-Wolbachia agent, AWZ1066S, with benzimidazole anthelmintics synergise to mediate sub-seven-day sterilising and curative efficacies in experimental models of filariasis
Shrilakshmi Hegde, Amy E. Marriott, Nicolas Pionnier, Andrew Steven, Christina Bulman, Emma Gunderson, Ian Vogel, Marianne Koschel, Alexandra Ehrens, Sara Lustigman, Denis Voronin, Nancy Tricoche, Achim Hoerauf, Marc P. Hübner, Judy Sakanari, Ghaith Aljay
Frontiers in Microbiology.2024;[Epub] CrossRef
Management and Incidence of Enterobius vermicularis Infestation in Appendectomy Specimens: A Cross-Sectional Study of 6359 Appendectomies
Zenon Pogorelić, Vlade Babić, Marko Bašković, Vladimir Ercegović, Ivana Mrklić
Journal of Clinical Medicine.2024; 13(11): 3198. CrossRef
An update on the current and emerging pharmacotherapy for the treatment of human ascariasis
Kam Lun Hon, Alexander K.C. Leung
Expert Opinion on Pharmacotherapy.2024;[Epub] CrossRef
Metabolic mechanism and pharmacological study of albendazole in secondary hepatic alveolar echinococcosis (HAE) model rats
Chaoqun Li, Yaogang zhang, Mingquan Pang, Yong Zhang, Chunhui Hu, Haining Fan, Audrey Odom John
Antimicrobial Agents and Chemotherapy.2024;[Epub] CrossRef
A randomized assessors-blind clinical trial to evaluate the safety and the efficacy of albendazole alone and in combination with mebendazole or pyrantel for the treatment of Trichuris trichiura infection in school-aged
Paul Alvyn Nguema Moure, Moustapha Nzamba Maloum, Gédéon Prince Manouana, Roméo-Aimé Laclong Lontchi, Mirabeau Mbong Ngwese, Jean Ronald Edoa, Jeannot Fréjus Zinsou, Brice Meulah, Saidou Mahmoudou, Elsy Mirna N'noh Dansou, Yabo Josiane Honkpehedji, Bayode
Antimicrobial Agents and Chemotherapy.2024;[Epub] CrossRef
A 16-year-old adolescent with a history of minor abdominal trauma diagnosed with a giant isolated primary splenic hydatid cyst: a case report
Abulfazl Vantankhah, Leila Ameri, Pegah Bahrami Taqanaki, Mohammad Jawed Bayat, Mahdi Parvizi Mashhadi
Annals of Medicine & Surgery.2024; 86(4): 2292. CrossRef
Therapeutic effect of curcumin nanoemulsion on cystic echinococcosis in BALB/c mice: a computerized tomography (CT) scan and histopathologic study evaluation
Mohamad Ghanimatdan, Seyed Mahmoud Sadjjadi, Fattaneh Mikaeili, Aref Teimouri, Seyed Hamed Jafari, Amin Derakhshanfar, Saeideh Hashemi-Hafshejani
BMC Complementary Medicine and Therapies.2024;[Epub] CrossRef
Assessment of milk biosafety for the content of antiparasitic drugs used for human consumption in different countries: Review
Dariga Utemuratova, Gaukhar Konuspayeva, Zaira Kabdullina, Nurlan Akhmetsadykov, Farida Amutova, Y. Alibek
BIO Web of Conferences.2024; 100: 02034. CrossRef
Revitalizing Cancer Treatment: Exploring the Role of Drug Repurposing
RamaRao Malla, Sathiyapriya Viswanathan, Sree Makena, Shruti Kapoor, Deepak Verma, Alluri Ashok Raju, Manikantha Dunna, Nethaji Muniraj
Cancers.2024; 16(8): 1463. CrossRef
Lethal effects of praziquantel and albendazole, on the cercariae of Echinochasmus sp. (Dietz, 1909) in-vitro
Mohammed E. El-Zeiny, Ola A. Abu Samak, Shereen A. Fahmy, Abdel Aziz A. Khidr
Journal of Parasitic Diseases.2024; 48(2): 320. CrossRef
Anthelminthic and antimicrobial effects of hedge woundwort (Stachys sylvatica L.) growing in Southern Kazakhstan
Aigerim Z. Mukhamedsadykova, Martyna Kasela, Kaldanay K. Kozhanova, Zuriyadda B. Sakipova, Wirginia Kukuła-Koch, Aleksandra Józefczyk, Łukasz Świątek, Barbara Rajtar, Magdalena Iwan, Przemysław Kołodziej, Agnieszka Ludwiczuk, Gulnara M. Kadyrbayeva, Gulnu
Frontiers in Pharmacology.2024;[Epub] CrossRef
Giant hydatid cyst of the ovary
Yuqin Liu, Liehong Wang, Xue Bai, Fei Wang
Asian Journal of Surgery.2024; 47(9): 3958. CrossRef
Efficacy and mechanism of energy metabolism dual-regulated nanoparticles (atovaquone-albendazole nanoparticles) against cystic echinococcosis
Yuehong Gong, Tianjiao Zhou, Ruijia Ma, Jianhua Yang, Yicong Zhao, Meichi Pan, Zhangjian Huang, Hao Wen, Hulin Jiang, Jianhua Wang
BMC Infectious Diseases.2024;[Epub] CrossRef
Dirofilariasis presenting as pleural effusion: a rare case report with unusual manifestations and treatment modalities
Rolanda Valčiukaitė-Žilinskienė, Birutė Zablockienė, Rolandas Zablockis
BMC Pulmonary Medicine.2024;[Epub] CrossRef
In Silico Study, Protein Kinase Inhibition and Molecular Docking Study of Benzimidazole Derivatives
Kamaraj Karthick, Kamaraj Abishek, Ebenezer Angel Jemima
Bioinformatics and Biology Insights.2024;[Epub] CrossRef
Case report: a rare case of intradural and pleural wall cystic echinococcosis
Jianchen Zhao, Lingping Xu, Xiaozhou Lin, Yonghao He, Yong Yang, Xin Du, Chunliang Li
BMC Infectious Diseases.2024;[Epub] CrossRef
Discovering Potential in Non-Cancer Medications: A Promising Breakthrough for Multiple Myeloma Patients
Omar S. Al-Odat, Emily Nelson, Tulin Budak-Alpdogan, Subash C. Jonnalagadda, Dhimant Desai, Manoj K. Pandey
Cancers.2024; 16(13): 2381. CrossRef
Gastrointestinal parasites of cats in the Middle East (2000−2023): A literature review
Mahdi Soroushianfar, Soheil Sadr, Alireza Sazmand, Shiva Dianaty, Javad Khedri, Rolf Karl Schuster, Hassan Borji
Parasitology International.2024; 102: 102919. CrossRef
Health Impact of Gnathostomiasis and its Integral Approach to Parasitic Infection: A Systematic Review
Gisnella María Cedeño Cajas, José Andrés Zaporta Ramos, Andrea Stefannia Flores Villacrés, Cesar Guevara
Salud, Ciencia y Tecnología.2024; 4: 1096. CrossRef
Efficacy and challenges of anti-PD1 in MSI-H mCRC: a case report on concurrent infections and ir-AIHA
Xiaxia Pei, Jun Zhao, Ruiying Luo, Lijun Da, Enxi Li, Hao Zhu, Yanhong Li, Yaoting Luo, Kun Tian, Zhiping Wang, Feixue Song
Frontiers in Oncology.2024;[Epub] CrossRef
Studies on absorption mechanism and pharmacokinetic properties of albendazole-bile acid conjugate: In vivo and in vitro
Zhimei Guo, Shizhen Tang, Kaili Nie, Jingshuai Liu, Chunhui Hu
Biomedicine & Pharmacotherapy.2024; 179: 117400. CrossRef
Unlocking the potential of signature-based drug repurposing for anticancer drug discovery
Sruti Biswal, Bibekanand Mallick
Archives of Biochemistry and Biophysics.2024; 761: 110150. CrossRef
Evaluation of the In-Vitro Effects of Albendazole, Mebendazole, and Praziquantel Nanocapsules against Protoscolices of Hydatid Cyst
Nooshinmehr Soleymani, Soheil Sadr, Cinzia Santucciu, Abbas Rahdar, Giovanna Masala, Hassan Borji
Pathogens.2024; 13(9): 790. CrossRef
Assessing the efficacy of Stemona collinsiae roots extract against third-stage larvae of Gnathostoma spinigerum and its safety profiles
Norinee Arlee, Sumate Ampawong, Sumet Kongkiatpaiboon, Yanin Limpanont, Kuntarat Arunrungvichian, Apanchanid Thepouyporn, Wallop Pakdee, Urusa Thaenkham
Heliyon.2024; 10(19): e38539. CrossRef
Deciphering Chemical Rules for Drug Penetration into Strongyloides
Miguel Marín, Javier Sánchez-Montejo, Sergio Ramos, Antonio Muro, Julio López-Abán, Rafael Peláez
Pharmaceutics.2024; 16(9): 1224. CrossRef
Exploring the DNA Recognition of Compounds Based on Benzimidazole and Benzothiazole: A Concise Review
Uzma Khan, Souvik Sur
Macromolecular Symposia.2024;[Epub] CrossRef
Online restricted access molecularly imprinted solid phase extraction coupled with electrospray ionization-tandem mass spectrometry for determination of mebendazole and albendazole in milk samples
Amanda Aparecida Marques Lourêdo, Helton Hanchuck Pereira, Rudy Bonfilio, Mariane Gonçalves Santos
Journal of Chromatography A.2024; 1737: 465466. CrossRef
Structural perspective into thiazoles and other azole derivatives as anthelmintic agents
M. Vajedpour, J. Abbasi Shiran, A. Ashnamoghadam, B. Kaboudin, N. Razzaghi-Asl
Acta Tropica.2024; 260: 107463. CrossRef
Molecular characterization and B-cell epitope analysis of the TSP11 gene in Echinococcus infection strains from Yunnan Province
Qian Xu, Zhengqing Wang, Jinrong Zi, Xuan Cai, Fangwei Wu, Benfu Li, Jia Peng, Jianxiong Li, Xinliu Yan, Ying Dong, Yaming Yang
Parasitology.2024; 151(10): 1108. CrossRef
Drug Repurposing for Cancer Treatment: A Comprehensive Review
Abdulaziz H. Al Khzem, Mohamed S. Gomaa, Mansour S. Alturki, Nada Tawfeeq, Mohammad Sarafroz, Shareefa M. Alonaizi, Alhassan Al Faran, Laela Ahmed Alrumaihi, Fatimah Ahmed Alansari, Abdullah Abbas Alghamdi
International Journal of Molecular Sciences.2024; 25(22): 12441. CrossRef
Programmed cell death pathways as targets for developing antifilarial drugs: Lessons from the recent findings
Nabarun Chandra Das, Pritha Chakraborty, Samapika Nandy, Abhijit Dey, Tabarak Malik, Suprabhat Mukherjee
Journal of Cellular and Molecular Medicine.2023; 27(19): 2819. CrossRef
Discovery of N-methylbenzo[d]oxazol-2-amine as new anthelmintic agent through scalable protocol for the synthesis of N-alkylbenzo[d]oxazol-2-amine and N-alkylbenzo[d]thiazol-2-amine derivatives
Pavitra Laohapaisan, Onrapak Reamtong, Jumreang Tummatorn, Charnsak Thongsornkleeb, Urusa Thaenkham, Poom Adisakwattana, Somsak Ruchirawat
Bioorganic Chemistry.2023; 131: 106287. CrossRef
Contribution of the TIM-3/Gal-9 immune checkpoint to tropical parasitic diseases
Christian Bailly
Acta Tropica.2023; 238: 106792. CrossRef
Emerging Perspectives on the Antiparasitic Mebendazole as a Repurposed Drug for the Treatment of Brain Cancers
Daniela Meco, Giorgio Attinà, Stefano Mastrangelo, Pierluigi Navarra, Antonio Ruggiero
International Journal of Molecular Sciences.2023; 24(2): 1334. CrossRef
Exposure of Paracoccidioides brasiliensis to Mebendazole Leads to Inhibition of Fungal Energy Production
Olivia Basso Rocha, Kleber Santiago Freitas e Silva, Dayane Moraes, Clayton Luiz Borges, Célia Maria de Almeida Soares, Maristela Pereira
Antibiotics.2023; 12(2): 206. CrossRef
Inhibition of albendazole and 2‐(2‐aminophenyl)‐1H‐benzimidazole against tyrosinase: mechanism, structure–activity relationship, and anti‐browning effect
Yiting Wen, Yujia Zhang, Xiaoli Zhang, Linjun Wang, Qiuxia Pan, Qiuhan Bai, Du Zhu, Weiming Chai
Journal of the Science of Food and Agriculture.2023; 103(6): 2824. CrossRef
In silico-chemogenomic repurposing of new chemical scaffolds for histoplasmosis treatment
Andressa Santana Santos, Laura Raniere Borges dos Anjos, Vinícius Alexandre Fiaia Costa, Vivianny Aparecida Queiroz Freitas, Ana Laura de Sene Amâncio Zara, Carolina Rodrigues Costa, Bruno Junior Neves, Maria do Rosário Rodrigues Silva
Journal of Medical Mycology.2023; 33(2): 101363. CrossRef
Identification of Promising Drug Candidates against Prostate Cancer through Computationally-Driven Drug Repurposing
Leonardo Bernal, Luca Pinzi, Giulio Rastelli
International Journal of Molecular Sciences.2023; 24(4): 3135. CrossRef
ASGARD is A Single-cell Guided Pipeline to Aid Repurposing of Drugs
Bing He, Yao Xiao, Haodong Liang, Qianhui Huang, Yuheng Du, Yijun Li, David Garmire, Duxin Sun, Lana X. Garmire
Nature Communications.2023;[Epub] CrossRef
Albendazole from ovine excrements in soil and plants under real agricultural conditions: Distribution, persistence, and effects
Martina Navrátilová, Ivan Vokřál, Josef Krátký, Petra Matoušková, Andrea Sochová, Daniela Vrábľová, Barbora Szotáková, Lenka Skálová
Chemosphere.2023; 324: 138343. CrossRef
Palladium-Catalyzed Carbonylative Synthesis of Diaryl Ketones from Arenes and Arylboronic Acids through C(sp2)–H Thianthrenation
Jiajun Zhang, Xiao-Feng Wu
Organic Letters.2023; 25(12): 2162. CrossRef
Popliteal Echinococcosis: A Long Journey from the Liver
Ergin Erginöz, Sefa Ergün, Emre Tunç, Salih Pekmezci
Acta Parasitologica.2023; 68(2): 463. CrossRef
Influence of halogen atoms and hydrogen bonds in the crystal structure of 1,2,4-trisubstituted imidazoles having haloaryl groups
Nerith Rocio Elejalde-Cadena, Mayra García-Olave, Mario A. Macías, Jaime Portilla
Journal of Molecular Structure.2023; 1286: 135662. CrossRef
Structural Changes, Biological Consequences, and Repurposing of Colchicine Site Ligands
Felipe Montecinos, Dan L. Sackett
Biomolecules.2023; 13(5): 834. CrossRef
Phase II, Double-Blinded, Randomized, Placebo-Controlled Clinical Trial Investigating the Efficacy of Mebendazole in the Management of Symptomatic COVID-19 Patients
Mohamed El-Tanani, Khaled Abdul-Aziz Ahmed, Ashok K. Shakya, Wesam G. Ammari, Abdel-Elah Al-Shudifat
Pharmaceuticals.2023; 16(6): 799. CrossRef
Polymeric Micelles Formulation of Combretastatin Derivatives with Enhanced Solubility, Cytostatic Activity and Selectivity against Cancer Cells
Igor D. Zlotnikov, Alexander A. Ezhov, Artem S. Ferberg, Sergey S. Krylov, Marina N. Semenova, Victor V. Semenov, Elena V. Kudryashova
Pharmaceutics.2023; 15(6): 1613. CrossRef
Novel Fluorescent Benzimidazole-Hydrazone-Loaded Micellar Carriers for Controlled Release: Impact on Cell Toxicity, Nuclear and Microtubule Alterations in Breast Cancer Cells
Rayna Bryaskova, Nikolai Georgiev, Nikoleta Philipova, Ventsislav Bakov, Kameliya Anichina, Maria Argirova, Sonia Apostolova, Irina Georgieva, Rumiana Tzoneva
Pharmaceutics.2023; 15(6): 1753. CrossRef
Regiospecific Reduction of 4,6‐Dinitrobenzimidazoles: Synthesis, Characterization, and Biological Evaluation
El Alami Abouelhaoul, Abdellatif El Kihel, Mustapha Ahbala, Hamid Sdassi, Leonhard H. F. Köhler, Patrick Bauchat, Thierry Roisnel, Tariq A. Khan, Ibrahim S. Al Nasr, Waleed S. Koko, Rainer Schobert, Bernhard Biersack
Chemistry & Biodiversity.2023;[Epub] CrossRef
Effect and Mechanism of Harmine on Echinococcosis Based on Network Pharmacology
Bei Chen, Jun Zhao, Liang Teng, Yimaierjiang Buhuliqianmu, Zhaohui Xu, Yuehong Gong, Huijing Gao
Natural Product Communications.2023;[Epub] CrossRef
Nanotechnology-based Approaches for the Treatment of Toxocariasis: A Prospective Review
Ali Jahanmahin, Hassan Borji
Journal of Veterinary Physiology and Pathology.2023; 2(2): 12. CrossRef
Albendazole Monotherapy for Pediatric Cystic Echinococcosis: A Case Series
Moshe Shmueli, Siham Elamour, Orli Sagi, Daniel Grupel, Zaki Assi, Shalom Ben-Shimol
Acta Parasitologica.2023; 68(3): 651. CrossRef
Application effect of phloroglucinol injection in elderly patients with spastic abdominal pain in emergency department
Yu-Fei Liu, Jian Chen
World Journal of Clinical Cases.2023; 11(23): 5440. CrossRef
Medical management of cystic echinococcosis
Peter L. Chiodini
Current Opinion in Infectious Diseases.2023; 36(5): 303. CrossRef
Immunological interaction during helminth and HIV co-infection: Integrative research needs for sub-Saharan Africa
Miranda N. Mpaka-Mbatha, Pragalathan Naidoo, Md Mazharul Islam, Ravesh Singh, Khethiwe N. Bhengu, Nomzamo Nembe-Mafa, Roxanne Pillay, Zamathombeni Duma, Abraham J. Niehaus, Zilungile L. Mkhize-Kwitshana
South African Journal of Science.2023;[Epub] CrossRef
Standard- and large-sized eggs of Trichuris trichiura in the feces of schoolchildren in the Yangon Region, Myanmar: Morphological and molecular analyses
Seungwan Ryoo, Bong-Kwang Jung, Sooji Hong, Hyejoo Shin, Hyemi Song, Hyun-Seung Kim, Jin-Youp Ryu, Woon-Mok Sohn, Sung-Jong Hong, Thi Thi Htoon, Htay Htay Tin, Jong-Yil Chai
Parasites, Hosts and Diseases.2023; 61(3): 317. CrossRef
Tubulin as a potential molecular target for resveratrol in Giardia lamblia trophozoites, in vitro and in silico approaches
José Roberto Vargas-Villanueva, Filiberto Gutiérrez-Gutiérrez, Mariana Garza-Ontiveros, Sendar Daniel Nery-Flores, Lizeth Guadalupe Campos-Múzquiz, Dagoberto Vazquez-Obregón, Raul Rodriguez-Herrera, Lissethe Palomo-Ligas
Acta Tropica.2023; 248: 107026. CrossRef
Tirapazamine combined with photodynamic therapy improves the efficacy of ABZSO nanoparticles on Echinococcosis granulosus via further enhancing “breaking-then-curing”
Yuehong Gong, Tianjiao Zhou, Wusimanjiang Aimaiti, Yuxia Lin, Yuan Xu, Jianhua Yang, Zhangjian Huang, Hao Wen, Hulin Jiang, Jianhua Wang
Journal of Photochemistry and Photobiology B: Biology.2023; 248: 112798. CrossRef
Benzimidazoles Containing Piperazine Skeleton at C-2 Position as Promising Tubulin Modulators with Anthelmintic and Antineoplastic Activity
Kameliya Anichina, Anelia Mavrova, Dimitar Vuchev, Galya Popova-Daskalova, Giada Bassi, Arianna Rossi, Monica Montesi, Silvia Panseri, Filip Fratev, Emilia Naydenova
Pharmaceuticals.2023; 16(11): 1518. CrossRef
The Use of Cyclodextrin Inclusion Complexes to Increase the Solubility and Pharmacokinetic Profile of Albendazole
Yili Ding, Zhiyuan Zhang, Charles Ding, Shufeng Xu, Zhe Xu
Molecules.2023; 28(21): 7295. CrossRef
Anti-cancer Potential of Hydatid Cyst-Derived Antigens: In Vivo Insights
Zeinab Hosseini, Mohaddeseh Jamali, Nikoo Sadat Hasheminezhad, Razieh Razmi, Rezvan Abbasi, Negar Jahani, Mahsa Mohammadian
Journal of Lab Animal Research.2023; 2(5): 33. CrossRef
Challenges and Prospective of Enhancing Hydatid Cyst Chemotherapy by Nanotechnology and the Future of Nanobiosensors for Diagnosis
Soheil Sadr, Narges Lotfalizadeh, Amir Mohammad Abbasi, Nooshinmehr Soleymani, Ashkan Hajjafari, Elahe Roohbaksh Amooli Moghadam, Hassan Borji
Tropical Medicine and Infectious Disease.2023; 8(11): 494. CrossRef
Structure-Based Optimization of Carbendazim-Derived Tubulin Polymerization Inhibitors through Alchemical Free Energy Calculations
Lucia Cano-González, Johan D. Espinosa-Mendoza, Félix Matadamas-Martínez, Ariana Romero-Velásquez, Miguel Flores-Ramos, Luis Fernando Colorado-Pablo, Marco Antonio Cerbón-Cervantes, Rafael Castillo, Ignacio González-Sánchez, Lilián Yépez-Mulia, Alicia Her
Journal of Chemical Information and Modeling.2023; 63(22): 7228. CrossRef
Metabolite profiling of Trichinella spiralis adult worms and muscle larvae identifies their excretory and secretory products
Naphatsamon Uthailak, Poom Adisakwattana, Peerut Chienwichai, Phornpimon Tipthara, Joel Tarning, Charin Thawornkuno, Tipparat Thiangtrongjit, Onrapak Reamtong
Frontiers in Cellular and Infection Microbiology.2023;[Epub] CrossRef
Mebendazole for Pinworm Infection in a Resident of a Facility for the Disabled
Fumihiro Hayakawa, Miwako Niwa, Haruo Niwa
An Official Journal of the Japan Primary Care Association.2023; 46(4): 153. CrossRef
Forecasting Gastric Cancer Diagnosis, Prognosis, and Drug Repurposing with Novel Gene Expression Signatures
Talip Yasir Demirtas, Md Rezanur Rahman, Merve Capkin Yurtsever, Esra Gov
OMICS: A Journal of Integrative Biology.2022; 26(1): 64. CrossRef
Nematicidal activity of naphthalimide–boron cluster conjugates
Anna Bogucka-Kocka, Przemysław Kołodziej, Anna Makuch-Kocka, Daria Różycka, Sebastian Rykowski, Jan Nekvinda, Bohumír Grüner, Agnieszka B. Olejniczak
Chemical Communications.2022; 58(15): 2528. CrossRef
Nutraceuticals and Phytotherapy in Men's Health: Antioxidants, Pro-oxidants, and a Novel Opportunity for Lifestyle Changes
Mark A. Moyad
Urologic Clinics of North America.2022; 49(2): 239. CrossRef
Simultaneous Determination of Levamisole, Mebendazole, and the Two Metabolite Residues of Mebendazole in Poultry Eggs by High-Performance Liquid Chromatography–Tandem Mass Spectrometry
Lan Chen, Zhaoyuan He, Peiyang Zhang, Yawen Guo, Yang Lu, Yayun Tang, Jinyuan Chen, Kaizhou Xie
Separations.2022; 9(4): 83. CrossRef
Herbal Medicines against Hydatid Disease: A Systematic Review (2000–2021)
Mughees Aizaz Alvi, Sadiq Khan, Rana Muhammad Athar Ali, Warda Qamar, Muhammad Saqib, Noman Yousaf Faridi, Li Li, Bao-Quan Fu, Hong-Bin Yan, Wan-Zhong Jia
Life.2022; 12(5): 676. CrossRef
Anthelmintic agents: vermicide and vermifuge
Gudisa Bereda
Insights in Biology and Medicine.2022; 6(1): 001. CrossRef
General overview of the current status of human foodborne trematodiasis
Jong-Yil Chai, Bong-Kwang Jung
Parasitology.2022; 149(10): 1262. CrossRef
Pharmacokinetic Characterization and Comparative Bioavailability of an Innovative Orodispersible Fixed-Dose Combination of Ivermectin and Albendazole: A Single Dose, Open Label, Sequence Randomized, Crossover Clinical Trial in Healthy Volunteers
Jaime Algorta, Alejandro Krolewiecki, Filipe Pinto, Silvia Gold, Jose Muñoz
Frontiers in Pharmacology.2022;[Epub] CrossRef
Formulation, in-vitro and ex-vivo evaluation of albendazole loaded ufasomal nanoformulation for topical delivery
Saba Abedin, Majid Karimi, Azin rezaeilaal, Zahra Jafariazar, Minoo Afshar
Journal of Drug Delivery Science and Technology.2022; 76: 103726. CrossRef
Albendazole-induced autophagy blockade contributes to elevated apoptosis in cholangiocarcinoma cells through AMPK/mTOR activation
Qing He, Yingxuan Yin, Xiaowen Pan, Yinjuan Wu, Xuerong Li
Toxicology and Applied Pharmacology.2022; 454: 116214. CrossRef
Tunable Polymeric Mixed Micellar Nanoassemblies of Lutrol F127/Gelucire 44/14 for Oral Delivery of Praziquantel: A Promising Nanovector against Hymenolepis nana in Experimentally-Infected Rats
Waleed M. Arafa, Mohammed H. Elkomy, Heba M. Aboud, Mona Ibrahim Ali, Samah S. Abdel Gawad, Shawky M. Aboelhadid, Emad A. Mahdi, Izzeddin Alsalahat, Heba Abdel-Tawab
Pharmaceutics.2022; 14(10): 2023. CrossRef
Identification of the transcriptome profile of Miamiensis avidus after mebendazole treatment
Hyunsu Kim, A-Reum Lee, Kyung-Yoon Jeon, Eun-Ji Ko, Hee-Jae Cha, Mee Sun Ock
Kosin Medical Journal.2022; 37(3): 203. CrossRef
Identifikasi cacing gastrointestinal pada walabi lincah di Taman Satwa Taru Jurug Surakarta
Prayoga Oktrio, Tetty Barunawati Siagian
ARSHI Veterinary Letters.2022; 6(1): 7. CrossRef
Genome-Wide Screening for Pathogenic Proteins and microRNAs Associated with Parasite–Host Interactions in Trypanosoma brucei
Zhiyuan Yang, Mai Shi, Xiaoli Zhang, Danyu Yao
Insects.2022; 13(11): 968. CrossRef
Synthesis and Anti-Cancer Applications of Benzimidazole Derivatives - Recent Studies
Yogesh K. Tyagi, Geetan jali, Ram Singh
Anti-Cancer Agents in Medicinal Chemistry.2022; 22(19): 3280. CrossRef
Synthesis and Anti-Ovarian Cancer Effects of Benzimidazole-2-Substituted Pyridine and Phenyl Propenone Derivatives
A-Long Cui, Zi-Ying Zhou, Ya-Li Wang, Lin-Tao Wu, Si-Tu Xue, Zhuo-Rong Li
Future Medicinal Chemistry.2022; 14(24): 1835. CrossRef
The Use of Mebendazole in COVID-19 Patients: An Observational Retrospective Single Center Study
Mostafa W. Galal, Mahmoud Ahmed, Yanqiu Shao, Chao Xing, Wael Ali, Abd Elhamid Baly, Abdallah Elfiky, Khaled Amer, John Schoggins, Hesham A. Sadek, Zeinab N. Gobara, Shih-Chao Lin
Advances in Virology.2022; 2022: 1. CrossRef
Albendazole from Ovine Excrements in Soil and Plants Under Real Agricultural Conditions: Distribution, Persistence, and Effects
Martina Navrátilová, Ivan Vokřál, Josef Krátký, Petra Matoušková, Andrea Sochová, Daniela Vrábľová, Barbora Szotáková, Lenka Skálová
SSRN Electronic Journal.2022;[Epub] CrossRef
Prevalence and management of eosinophilia based on periodic health examinations in primary care clinics
Thareerat Ananchaisarp, Panya Chamroonkiadtikun, Jakrawadee Julamanee, Kewalee Perdvong, Thitawan Chimpalee, Nutnicha Rattanavirakul, Nattawat Leelarujijaroen, Tiprada Hathaipitak, Thanarat Tantinam
Asian Biomedicine.2022; 16(5): 273. CrossRef
Hydatid disease as a rare cause of neck swelling: Two cases report
Makram Tbini, Rim Lahiani, Houda Guelmami, Habib Jaafoura, Ines Riahi, Mamia Bensalah
International Journal of Surgery Case Reports.2021; 87: 106486. CrossRef
Microtubule Targeting Agents in Disease: Classic Drugs, Novel Roles
Linda Wordeman, Juan Jesus Vicente
Cancers.2021; 13(22): 5650. CrossRef
Cyclodextrin Dispersion of Mebendazole and Flubendazole Improves In Vitro Antiproliferative Activity
Daliana Minda, Alexandra Mioc, Christian Banciu, Codruța Soica, Roxana Racoviceanu, Marius Mioc, Ioana Macasoi, Stefana Avram, Adrian Voicu, Andrei Motoc, Cristina Trandafirescu
Processes.2021; 9(12): 2185. CrossRef
Failure of Repeated MDA with Albendazole for Trichuriasis Control in Schoolchildren of the Yangon Region, Myanmar
Sooji Hong, Bong-Kwang Jung, Hyemi Song, Jaeeun Cho, Woon-Mok Sohn, Sung-Jong Hong, Jin-Youp Ryu, Hyun-Seung Kim, Mun-Hyoo Jeong, Thi Thi Htoon, Htay Htay Tin, Jong-Yil Chai
The Korean Journal of Parasitology.2021; 59(6): 607. CrossRef
Chemical and pharmacological characterization of anthelmintic benzimidazoles
Kelemen Hajnal, Mărcuțiu Petra Edina, Rausz Adrienn, Papp Lajos-Attila
Bulletin of Medical Sciences.2021; 94(2): 88. CrossRef
10.1016/s1155-1968(23)45969-x

CrossRef Listing of Deleted DOIs.2000;[Epub] CrossRef

55,328 View
866 Download
140 Web of Science
Crossref

An Overview of Fish-borne Nematodiases among Returned Travelers for Recent 25 Years? Unexpected Diseases Sometimes Far Away from the Origin: Jorge Costa Eiras, Gilberto Cezar Pavanelli, Ricardo Massato Takemoto, Yukifumi Nawa; Korean J Parasitol 2018;56(3):215-227.
Published online June 30, 2018; DOI: https://doi.org/10.3347/kjp.2018.56.3.215

Abstract
PDF

Along with globalization of traveling and trading, fish-borne nematodiases seems to be increasing in number. However, apart from occasional and sporadic case reports or mini-reviews of particular diseases in particular countries, an overview of fish-borne nematodiasis among travelers have never been performed. In this review, we gathered fishborne nematodiasis among travelers for recent 25 years by an extensive global literature survey using appropriate keywords, e.g. travelers diseases, human infection, anisakiasis, gnathostomiasis, capillariasis, sushi, sashimi, ceviche, Gnathostoma, Pseudoterranova, Anisakis, Capillaria, etc., as well as various combinations of these key words. The Internet search engines PubMed, Medline, Google and Googler Scholar were used as much as possible, and the references of every paper were checked in order to identify useful and reliable publications. The results showed unexpectedly high incidence of gnathostomiasis and low incidence of anisakidosis. The different incidence values of the infection with several fish-borne zoonotic nematode species are discussed, as well as some epidemiological aspects of the infections. The difficulties of differential diagnosis in non-endemic countries are emphasized. It is concluded that travelers must avoid risky behaviors which can lead to infection and that physicians and health authorities must advice travelers on the risks of eating behaviors during travel.

Citations

Citations to this article as recorded by

Detection of zoonotic nematodes in brown trout, Salmo trutta, an introduced popular edible freshwater fish in Australia
Shokoofeh Shamsi, Luke Pearce
Parasitology Research.2025;[Epub] CrossRef
Advanced genomic research in understanding fish-borne zoonotic parasitic infection
Sk Injamamul Islam, Piyanan Taweethavonsawat
Microbial Pathogenesis.2025; 200: 107367. CrossRef
Fish Pathogens and Associated Zoonotic Risks in Aquaculture: A Global One Health Perspective
Fredrick Juma Syanya, Sajna Beegum, Zachariy Oreko Winam, Fazeena Fariq, A. R. Nikhila Khanna, Megha Lovejan, Mujeeb Rahiman K. M., Harikrishnan Mahadevan
Aquaculture, Fish and Fisheries.2025;[Epub] CrossRef
Parasitic Diseases of Upper Gastrointestinal Tract
Heung Up Kim
The Korean Journal of Helicobacter and Upper Gastrointestinal Research.2024; 24(2): 127. CrossRef
Histopathological, morphological, and molecular characterization of fish-borne zoonotic parasite Eustrongylides Excisus infecting Northern pike (Esox lucius) in Iran
Hooman Rahmati-Holasoo, Mohammad Azizzadeh, Hosseinali Ebrahimzadeh Mousavi, Sara Shokrpoor, Zahra Ziafati Kafi, Amin Marandi
BMC Veterinary Research.2024;[Epub] CrossRef
Is it possible to eliminate or eradicate human fish-borne parasitic diseases? A sweet dream or a nightmare?
Jorge C. Eiras
Current Research in Parasitology & Vector-Borne Diseases.2024; 6: 100203. CrossRef
Recent Data on Nematode Infestation of Anchovy (Engraulis encrasicolus) on the Romanian Black Sea Coast
Aurelia Țoțoiu, Magda Nenciu, Victor Niță
Journal of Marine Science and Engineering.2024; 12(8): 1257. CrossRef
Food Safety: Pathological and Biochemical Responses of Nile Tilapia (Oreochromis niloticus) to Parasitological Infestation and Heavy Metals Pollution in Aquaculture System, Jeddah, Saudi Arabia
Muslimah N. Alsulami, Sarah Khaled Baowidan, Rabab M. Aljarari, Haleema H. Albohiri, Samar A. Khan, Elham Ali Elkhawass
Animals.2024; 15(1): 39. CrossRef
Occurrence and characterisation of Eustrongylides species in Australian native birds and fish
Shokoofeh Shamsi, Nidhish Francis, Juliet Masiga, Diane P. Barton, Xiaocheng Zhu, Luke Pearce, Matthew McLellan
Food and Waterborne Parasitology.2023; 30: e00189. CrossRef
The risk-based control of the safety and quality of freshwater fish for sale in the agri-food market
Vasyl Liasota, Nataliia Bukalova, Nadiia Bohatko, Nataliia Grynevych, Alla Sliusarenko, Serhii Sliusarenko, Tetiana Prylipko, Volodymyr Dzhmil
Potravinarstvo Slovak Journal of Food Sciences.2023; 17: 200. CrossRef
The Occurrence of Freshwater Fish-Borne Zoonotic Helminths in Italy and Neighbouring Countries: A Systematic Review
Vasco Menconi, Elena Lazzaro, Michela Bertola, Lisa Guardone, Matteo Mazzucato, Marino Prearo, Ewa Bilska-Zajac, Luana Cortinovis, Amedeo Manfrin, Giuseppe Arcangeli, Giorgia Angeloni
Animals.2023; 13(24): 3793. CrossRef
Assessments and Identification of Selected Fish-Borne Zoonotic Parasites in Nile Tilapia and African Catfish Species in Lakes of Haramaya District, Ethiopia
Zinabu Tesfaye, Adem Hiko, Dinaol Belina, Merga Firdisa, Janice Ragaza
Aquaculture Research.2023; 2023: 1. CrossRef
DNA Sequence Based Molecular Identification of Eustrongylides excisus Larvas (Nematoda) in Sander Lucioperca from Lake Eğirdir
Kevser ÖZTÜRK, Mehmet Oğuz ÖZTÜRK
Mehmet Akif Ersoy Üniversitesi Fen Bilimleri Enstitüsü Dergisi.2023; 14(2): 346. CrossRef
Five-years management of an emerging parasite risk (Eustrongylides sp., Nematoda) in a fishery supply chain located on Trasimeno Lake (Italy)
Raffaella Franceschini, Lisa Guardone, Andrea Armani, David Ranucci, Rossana Roila, Andrea Valiani, Francesca Susini, Raffaella Branciari
Food Control.2022; 136: 108858. CrossRef
Zoonotic diseases of fish and their prevention and control
Mina Ziarati, Mohammad Jalil Zorriehzahra, Fatemeh Hassantabar, Zibandeh Mehrabi, Manish Dhawan, Khan Sharun, Talha Bin Emran, Kuldeep Dhama, Wanpen Chaicumpa, Shokoofeh Shamsi
Veterinary Quarterly.2022; 42(1): 95. CrossRef
Paratenic hosts of Angiostrongylus cantonensis and their relation to human neuroangiostrongyliasis globally
Helena C. Turck, Mark T. Fox, Robert H. Cowie
One Health.2022; 15: 100426. CrossRef
First detection of Eustrongylides excisus (Nematoda: Dioctophymatidae) in big-scale sand smelt (Atherina boyeri) from the lake Massaciuccoli (Northwest Tuscany, Italy): implications for public health and seafood quality
L. Guardone, E. Ricci, F. Susini, E. Polsinelli, G. Guglielmone, A. Armani
Food Control.2021; 120: 107517. CrossRef
An annotated checklist of the eukaryotic parasites of humans, exclusive of fungi and algae
Blaine A. Mathison, Sarah G. H. Sapp
ZooKeys.2021; 1069: 1. CrossRef
Could Fish Feeding Behaviour and Size Explain Prevalence Differences of the Nematode Eustrongylides excisus among Species? The Case Study of Lake Garda
Vasco Menconi, Perla Tedesco, Paolo Pastorino, Ivano Confortini, Giuseppe Esposito, Mattia Tomasoni, Davide Mugetti, Andrea Gustinelli, Alessandro Dondo, Elisabetta Pizzul, Maria Letizia Fioravanti, Marino Prearo
Water.2021; 13(24): 3581. CrossRef
Human infection with Pseudoterranova cattani by ingestion of “ceviche” in Buenos Aires, Argentina
Claudia I. Menghi, Claudia L. Gatta, Liliana E. Arias, Gabriela Santoni, Federico Nicola, Jorgelina Smayevsky, Maria F. Degese, Silvio J. Krivokapich
Revista Argentina de Microbiología.2020; 52(2): 118. CrossRef
Investigation of Anisakis larvae in different products of ready-to-eat fish meat and imported frozen fish in Turkey
Emrah Simsek, Gokmen Zafer Pekmezci, Alparslan Yildirim, Onder Duzlu, Zuhal Onder, Arif Ciloglu, Neslihan Sursal, Erdal Yilmaz, Zafer Gonulalan, Abdullah Inci
International Journal of Food Microbiology.2020; 333: 108829. CrossRef
Gnathostomiasis Acquired by Visitors to the Okavango Delta, Botswana
John Frean
Tropical Medicine and Infectious Disease.2020; 5(1): 39. CrossRef
Molecular identification and genetic diversity of Gnathostoma spinigerum larvae in freshwater fishes in southern Lao PDR, Cambodia, and Myanmar
Patcharaporn Boonroumkaew, Oranuch Sanpool, Rutchanee Rodpai, Lakkhana Sadaow, Chalermchai Somboonpatarakun, Sakhone Laymanivong, Win Pa Pa Aung, Mesa Un, Porntip Laummaunwai, Pewpan M. Intapan, Wanchai Maleewong
Parasitology Research.2019; 118(5): 1465. CrossRef
Morphological and Molecular Characterization of Larval and Adult Stages of Eustrongylides excisus (Nematoda: Dioctophymatoidea) with Histopathological Observations
Angelica Mazzone, Monica Caffara, Andrea Gustinelli, Francesco Agnetti, Elisa Sgariglia, Giovanni Lo Vaglio, Francesco Quaglio, Maria L. Fioravanti
Journal of Parasitology.2019; 105(6): 882. CrossRef

16,983 View
278 Download
23 Web of Science
Crossref

Brief Communication

First Report of Clavinema mariae (Nematoda: Philometridae) in Cultured Rockfish, Sebastes schlegeli, in Cheonsuman (Bay), the Republic of Korea: Hyun-Ja Han, Jung Soo Seo, Jeong Su Park, Haeng Lim Lee, Han Gill Seo, Sung Hee Jung, Se Ryun Kwon; Korean J Parasitol 2017;55(2):219-224.
Published online April 30, 2017; DOI: https://doi.org/10.3347/kjp.2017.55.2.219

Abstract
PDF

In July 2012, philometrid nematodes were discovered in cultured rockfish (Sebastes schlegeli) in Cheonsuman (Bay), the Republic of Korea. The nematodes were detected in the epithelial tissues of the rockfish and were identified as Clavinema mariae based on morphological studies using light and scanning electron microscopy. They revealed the characteristics same as previously identified C. mariae, notably having a long body with narrow posterior half, no caudal projection, a cylindrical-shaped esophagus, a well-developed anterior bulbous part of the esophagus, cephalic papillae, and a dorsal esophageal gland. This is the first confirmation of C. mariae infection in rockfish in Korea.

Citations

Citations to this article as recorded by

Nematode Parasites of Rockfish (Sebastes spp.) and Cod (Gadus spp.) from Waters near Kodiak Island Alaska, USA
Mehmet Cemal Oğuz, Andrea McRae Campbell, Samuel P. Bennett, Mark C. Belk
Diversity.2021; 13(9): 436. CrossRef
New records of philometrids (Nematoda: Philometridae) from marine fishes off Japan, including description of Philometra kidakoi sp. n. and Congerinema japonicum gen. et sp. n.
Frantisek Moravec, Kazuya Nagasawa, Masato Nitta, Atsushi Tawa
Folia Parasitologica.2019;[Epub] CrossRef

9,274 View
138 Download
2 Web of Science
Crossref

Original Article

Molecular Characterization of Nippostrongylus brasiliensis (Nematoda: Heligmosomatidae) from Mus musculus in India: Anshu Chaudhary, Urvashi Goswami, Hridaya Shanker Singh; Korean J Parasitol 2016;54(6):743-750.
Published online December 31, 2016; DOI: https://doi.org/10.3347/kjp.2016.54.6.743

Abstract
PDF

Mus musculus (Rodentia: Muridae) has generally been infected with a rodent hookworm Nippostrongylus brasiliensis. In this report, we present morphological and molecular identification of N. brasiliensis by light and scanning electron microscopy and PCR amplification of mitochondrial cytochrome c oxidase subunit 1 (cox1) gene and the protein sequences encoded by cox1 gene, respectively. Despite the use of N. brasiliensis in many biochemistry studies from India, their taxonomic identification was not fully understood, especially at the species level, and no molecular data is available in GenBank from India. Sequence analysis of cox1 gene in this study revealed that the present specimen showed close identity with the same species available in GenBank, confirming that the species is N. brasiliensis. This study represents the first record of molecular identification of N. brasiliensis from India and the protein structure to better understand the comparative phylogenetic characteristics.

Citations

Citations to this article as recorded by

New data on the life cycle of Nippostrongylus brasiliensis (Travassos, 1914) (Nematoda: Heligmosomidae): development of eggs and larval stages in the intestine of naturally infected Rattus norvegicus (Berkenhout, 1769)
María Teresa Galán-Puchades, Mercedes Gómez-Samblás, María Trelis, Antonio Osuna, Rubén Bueno-Marí, Sandra Sáez-Durán, David Bruce Conn, Màrius V. Fuentes
Parasitology Research.2025;[Epub] CrossRef
Severe Infection of Nippostrongylus brasiliensis in Bandicota bengalensis Inhabiting Commensal Areas of Punjab, India: Prevalence, Risk Factor Analysis, Molecular Identification and Phylogenesis
Shivani Rara, Neena Singla, Sukhmanpreet Kaur Brar, Dimple Mandla, Lachhman Das Singla
Acta Parasitologica.2023; 68(1): 172. CrossRef
In Silico dszC Gene Analysis, Modeling and Validation of Dibenzothiophene monooxygenase (DszC Enzyme) of Dibenzothiophene Desulfurizing Streptomyces sp.VUR PPR 102
P. Praveen Reddy, V. UmaMaheswara Rao
Biosciences Biotechnology Research Asia.2023; 20(3): 935. CrossRef
Morphological Re-Description and 18 S rDNA Sequence Confirmation of the Pinworm Aspiculuris tetraptera (Nematoda, Heteroxynematidae) Infecting the Laboratory Mice Mus musculus
Rewaida Abdel-Gaber, Fathy Abdel-Ghaffar, Saleh Al Quraishy, Kareem Morsy, Rehab Saleh, Heinz Mehlhorn
Journal of Nematology.2018; 50(2): 117. CrossRef

11,148 View
170 Download
4 Web of Science
Crossref

Brief Communications

New Record of Schistorophus cirripedesmi (Nematoda: Acuariidae) from a Bar-Tailed Godwit, Limosa lapponica baueri (Charadriformes: Scolopacidae) in Korea: Seongjun Choe, Hyun Kim, Junsik Lim, Dongmin Lee, Hansol Park, Hyeong-Kyu Jeon, Heejong Kim, Youngjun Kim, Keeseon S. Eom; Korean J Parasitol 2016;54(3):349-355.
Published online June 30, 2016; DOI: https://doi.org/10.3347/kjp.2016.54.3.349

Abstract
PDF

In July 2014, a nematode species, Schistorophus cirripedesmi Rhizhikov and Khokhlova, 1964, was recovered from a bar-tailed godwit, Limosa lapponica baueri that was stored in a -20˚C freezer in the Chungnam Wild Animal Rescue Center. The bird was collected in 2012 from the coastal region of Pyeongtaek-si (City), Gyeonggi-do (Province) in the Republic of Korea, although the exact date is not clear. At necropsy, 9 nematodes were found in the gizzard of the bird. The parasites had 4 horn-like cephalic cuticular ornamentations. After morphometric comparison and morphological observations, including scanning electron microscopy, the nematodes were identified as S. cirripedesmi. This is the first description of a nematode species in a shorebird in Korea. This is also the first time this genus and species have been found in Korea.

8,758 View
151 Download

Three Nematode Species Recovered from Terrestrial Snakes in Republic of Korea: Seongjun Choe, Junsik Lim, Hyun Kim, Youngjun Kim, Heejong Kim, Dongmin Lee, Hansol Park, Hyeong-Kyu Jeon, Keeseon S. Eom; Korean J Parasitol 2016;54(2):205-213.
Published online April 30, 2016; DOI: https://doi.org/10.3347/kjp.2016.54.2.205

Abstract
PDF

The majority of parasitological studies of terrestrial snakes in Korea have focused on zoonotic parasites. However, in the present study, we describe 3 unrecorded nematode species recovered from 5 species of snakes (n=6) in Korea. The examined snakes, all confiscated from illegal hunters, were donated by the Chungnam Wild Animal Rescue Center and Korean Broadcasting System in July 2014 and February 2015. Light and scanning electron microscopies on the shapes of spicules that are either bent or straight (kalicephalids) and the presence of the intestinal cecum (ophidascarids) figured out 3 nematodes; Kalicephalus brachycephalus Maplestone, 1931, Kalicephalus sinensis Hs?, 1934, and Ophidascaris excavata Hs? and Hoeppli, 1934. These 3 species of nematode faunas are recorded for the first time in Korea.

Citations

Citations to this article as recorded by

An update on the conservation status and ecology of Korean terrestrial squamates
Daniel Macias, Yucheol Shin, Amaël Borzée
Journal for Nature Conservation.2021; 60: 125971. CrossRef
The mitochondrial genome sequence analysis of Ophidascaris baylisi from the Burmese python (Python molurus bivittatus)
Qi Zhao, Asmaa M.I. Abuzeid, Long He, Tingting Zhuang, Xiu Li, Jumei Liu, Shilan Zhu, Xiaoyu Chen, Guoqing Li
Parasitology International.2021; 85: 102434. CrossRef
Morphologic and morphometric characteristics of ascaroid worm, Ophidascaris piscatori in Xenochrophis piscator snake in Sidoarjo, Indonesia
Lucia Tri Suwanti, Inggarsetya Syah Audini, Setiawan Koesdarto, Emmanuel Djoko Poetranto
Veterinary World.2018; 11(8): 1159. CrossRef

12,272 View
215 Download
3 Web of Science
Crossref

Original Article

Identification and Prevalence of Globocephalus samoensis (Nematoda: Ancylostomatidae) among Wild Boars (Sus scrofa coreanus) from Southwestern Regions of Korea: Kyu-Sung Ahn, Ah-Jin Ahn, Tae-Hoon Kim, Guk-Hyun Suh, Kyoung-Woong Joo, Sung-Shik Shin; Korean J Parasitol 2015;53(5):611-618.
Published online October 29, 2015; DOI: https://doi.org/10.3347/kjp.2015.53.5.611

Abstract
PDF

This study describes the first record of Globocephalus samoensis (Nematoda: Ancylostomatidae) recovered in wild boars from southwestern regions of Korea. Gastrointestinal tracts of 111 Korean wild boars (Sus scrofa coreanus) hunted from mountains in Suncheon-si, Gwangyang-si, and Boseong-gun between 2009 and 2012 were examined for their visceral helminths. G. samoensis, as identified by morphological characteristics of the head and tail, were recovered from the small intestine of 51 (45.9%) wild boars. Worms were found from 7 of 28 wild boars (25.0%) from Suncheon-si, 40 of 79 (50.6%) from Gwangyang-si, and all 4 (100%) from Boseong-gun. The length of adult females was 7.2±0.5 mm, and the thickest part of the body measured the average 0.47±0.03 mm, while those of males were 6.52±0.19 and 0.37±0.02 mm, respectively. The buccal cavity was equipped with a pair of large and bicuspid subventral lancets near the base of the capsule. The average length of spicules of males was 0.45±0.02 mm. By the present study, G. samoensis is recorded for the first time in southwestern regions of Korea. Additionally, morphological characteristics and identification keys provided in the present study will be helpful in the faunistic and taxonomic studies for strongylid nematodes in both domestic and wild pigs. The infection of G. samoensis apparently did not elicit pathologic lesions, as revealed by macroscopic observation during the autopsy of all wild boars in this study.

Citations

Citations to this article as recorded by

Survey the Occurrence of Globocephalus urosubulatus (Nematoda: Ancylostomatidae) in Wild Boars (Sus scrofa) in the State of São Paulo, Brazil
Michel dos Santos Pinto, João Alfredo Biagi Camargo Neto, Maria Julia Hernandes de Freitas, Bárbara Fuzetto Florentino, Natália de Souza Sapatera, Fernando Paiva, Alex Akira Nakamura, Daniela Bernadete Rozza, Simone Baldini Lucheis, Katia Denise Saraiva B
Veterinary Sciences.2024; 11(8): 370. CrossRef
Globocephalus urosubulatus (Alessandrini, 1909) (Nematoda: Ancylostomatidae) in Brazil: a morphological revisitation
Raul Henrique da Silva Pinheiro, Sérgio Melo, Raimundo Nonato Moraes Benigno, Elane Guerreiro Giese
Revista Brasileira de Parasitologia Veterinária.2021;[Epub] CrossRef
SURVEY OF GASTROINTESTINAL HELMINTHS OF FERAL HOGS FROM TEXAS
Kalin M. Skinner, Megan R. Wise De Valdez
The Southwestern Naturalist.2019; 63(2): 91. CrossRef
Gastrointestinal helminths from the common warthog,Phacochoerus africanus(Gmelin) (Suidae), in KwaZulu-Natal Province, South Africa, with comments on helminths of Suidae and Tayassuidae worldwide
Kerstin Junker, Andrea Spickett, Monlee Swanepoel, Boris R. Krasnov, Joop Boomker, Louwrens C. Hoffman
Parasitology.2019; 146(12): 1541. CrossRef
The diversity and impact of hookworm infections in wildlife
Mauricio Seguel, Nicole Gottdenker
International Journal for Parasitology: Parasites and Wildlife.2017; 6(3): 177. CrossRef

14,439 View
153 Download
5 Web of Science
Crossref

Mini Reviews

DEAD/DExH-Box RNA Helicases in Selected Human Parasites: Laurence A. Marchat, Silvia I. Arzola-Rodr?guez, Olga Hernandez-de la Cruz, Itzel Lopez-Rosas, Cesar Lopez-Camarillo; Korean J Parasitol 2015;53(5):583-595.
Published online October 29, 2015; DOI: https://doi.org/10.3347/kjp.2015.53.5.583

Abstract
PDF

DEAD/DExH-box RNA helicases catalyze the folding and remodeling of RNA molecules in prokaryotic and eukaryotic cells, as well as in many viruses. They are characterized by the presence of the helicase domain with conserved motifs that are essential for ATP binding and hydrolysis, RNA interaction, and unwinding activities. Large families of DEAD/DExH-box proteins have been described in different organisms, and their role in all molecular processes involving RNA, from transcriptional regulation to mRNA decay, have been described. This review aims to summarize the current knowledge about DEAD/DExH-box proteins in selected protozoan and nematode parasites of medical importance worldwide, such as Plasmodium falciparum, Leishmania spp., Trypanosoma spp., Giardia lamblia, Entamoeba histolytica, and Brugia malayi. We discuss the functional characterization of several proteins in an attempt to understand better the molecular mechanisms involving RNA in these pathogens. The current data also highlight that DEAD/DExH-box RNA helicases might represent feasible drug targets due to their vital role in parasite growth and development.

Citations

Citations to this article as recorded by

ATPase activity profiling of three human DExD/H-box RNA helicases
Fengling Li, U Hang Chan, Julia Garcia Perez, Hong Zeng, Irene Chau, Yanjun Li, Almagul Seitova, Levon Halabelian
SLAS Discovery.2025; 32: 100229. CrossRef
The extreme C-terminal region of the phage BFK20 gp41 helicase has a role in DNA binding, protein-ATP interactions and ATPase activity
Nora Halgasova, Lucia Bocanova, Jacob A. Bauer, Barbora Niku, Kristina Papayova, Gabriela Bukovska
Biochimie.2025; 238: 43. CrossRef
Recombinant TgDDX3X DEAD-box protein confers partial protection in murine models of acute and chronic toxoplasmosis
Shuai Wang, Jinghui Wang, Youke Fan, Haina Zhang, Junru Wu, Tingting Ying, Hangbin Ma, Qiangqiang Wang, Longkang Wang, Yuanfeng Wang, Xiaowei Tian, Xuefang Mei, Zhenchao Zhang, Zhenke Yang
Acta Tropica.2025; 270: 107780. CrossRef
The core exosome proteome of Trichomonas vaginalis
Seow-Chin Ong, Hong-Wei Luo, Wei-Hung Cheng, Fu-Man Ku, Chih-Yu Tsai, Po-Jung Huang, Chi-Ching Lee, Yuan-Ming Yeh, Rose Lin, Cheng-Hsun Chiu, Petrus Tang
Journal of Microbiology, Immunology and Infection.2024; 57(2): 246. CrossRef
Screening and Structural Characterization of Heat Shock Response Elements (HSEs) in Entamoeba histolytica Promoters
David Dorantes-Palma, Salvador Pérez-Mora, Elisa Azuara-Liceaga, Ernesto Pérez-Rueda, David Guillermo Pérez-Ishiwara, Misael Coca-González, María Olivia Medel-Flores, Consuelo Gómez-García
International Journal of Molecular Sciences.2024; 25(2): 1319. CrossRef
Evaluation of protective efficacy of recombinant Toxoplasma gondii DDX39 protein vaccine against acute and chronic T. gondii infection in mice
Jinghui Wang, Yuanfeng Wang, Haina Zhang, Hangbin Ma, Qiangqiang Wang, Longkang Wang, Youke Fan, Xiaowei Tian, Xuefang Mei, Zhenchao Zhang, Shuai Wang, Zhenke Yang
Acta Tropica.2024; 260: 107442. CrossRef
Single-chain models illustrate the 3D RNA folding shape during translation
Tianze Guo, Olivia L. Modi, Jillian Hirano, Horacio V. Guzman, Tatsuhisa Tsuboi
Biophysical Reports.2022; 2(3): 100065. CrossRef
Role of ATP in the RNA Translocation Mechanism of SARS-CoV-2 NSP13 Helicase
Ryan Weber, Martin McCullagh
The Journal of Physical Chemistry B.2021; 125(31): 8787. CrossRef
Plasmodium falciparum DDX55 is a nucleocytoplasmic protein and a 3′-5′ direction-specific DNA helicase
Rahena Yasmin, Inderjeet Kaur, Renu Tuteja
Protoplasma.2020; 257(4): 1049. CrossRef
Plasmodium falciparum specific helicase 2 is a dual, bipolar helicase and is crucial for parasite growth
Manish Chauhan, Renu Tuteja
Scientific Reports.2019;[Epub] CrossRef
Investigation of hub genes and their nonsynonymous single nucleotide polymorphism analysis in Plasmodium falciparum for designing therapeutic methodologies using next-generation sequencing approach
SanjayKumar Singh, SudhakaraM Reddy
Indian Journal of Pharmacology.2019; 51(6): 389. CrossRef
Characterization of MEDLE-1, a protein in early development of Cryptosporidium parvum
Jilan Fei, Haizhen Wu, Jiayuan Su, Chanchan Jin, Na Li, Yaqiong Guo, Yaoyu Feng, Lihua Xiao
Parasites & Vectors.2018;[Epub] CrossRef
The steroid derivative 6-aminocholestanol inhibits the DEAD-box helicase eIF4A (LieIF4A) from the Trypanosomatid parasite Leishmania by perturbing the RNA and ATP binding sites
Yosser Zina Abdelkrim, Emna Harigua-Souiai, Mourad Barhoumi, Josette Banroques, Arnaud Blondel, Ikram Guizani, N. Kyle Tanner
Molecular and Biochemical Parasitology.2018; 226: 9. CrossRef
Structural and evolutionary analysis of Leishmania Alba proteins
Kauê Santana da Costa, João Marcos Pereira Galúcio, Elvis Santos Leonardo, Guelber Cardoso, Élcio Leal, Guilherme Conde, Jerônimo Lameira
Molecular and Biochemical Parasitology.2017; 217: 23. CrossRef
Plasmodium falciparum specific helicase 3 is nucleocytoplasmic protein and unwinds DNA duplex in 3′ to 5′ direction
Manish Chauhan, Mohammed Tarique, Renu Tuteja
Scientific Reports.2017;[Epub] CrossRef

12,752 View
173 Download
18 Web of Science
Crossref

Serine Proteases of Parasitic Helminths: Yong Yang, Yun jun Wen, Ya Nan Cai, Isabelle Vall?e, Pascal Boireau, Ming Yuan Liu, Shi Peng Cheng; Korean J Parasitol 2015;53(1):1-11.
Published online February 27, 2015; DOI: https://doi.org/10.3347/kjp.2015.53.1.1

Abstract
PDF

Serine proteases form one of the most important families of enzymes and perform significant functions in a broad range of biological processes, such as intra- and extracellular protein metabolism, digestion, blood coagulation, regulation of development, and fertilization. A number of serine proteases have been identified in parasitic helminths that have putative roles in parasite development and nutrition, host tissues and cell invasion, anticoagulation, and immune evasion. In this review, we described the serine proteases that have been identified in parasitic helminths, including nematodes (Trichinella spiralis, T. pseudospiralis, Trichuris muris, Anisakis simplex, Ascaris suum, Onchocerca volvulus, O. lienalis, Brugia malayi, Ancylostoma caninum, and Steinernema carpocapsae), cestodes (Spirometra mansoni, Echinococcus granulosus, and Schistocephalus solidus), and trematodes (Fasciola hepatica, F. gigantica, and Schistosoma mansoni). Moreover, the possible biological functions of these serine proteases in the endogenous biological phenomena of these parasites and in the host-parasite interaction were also discussed.

Citations

Citations to this article as recorded by

N-terminomics profiling of host proteins targeted by excretory-secretory proteases of the nematode Angiostrongylus vasorum identifies points of interaction with canine coagulation and complement cascade
Nina Germitsch, Tobias Kockmann, Manuela Schnyder, Lucienne Tritten, Elham Kazemirad
PLOS ONE.2025; 20(1): e0316217. CrossRef
Administration of Trichinella spiralis Antigens Alleviated Diabetic Nephropathy in Diabetic Mice
Asmaa M. El-kady, Sarah A. Altwaim, Haleema H. Albohiri, Majed H. Wakid, Khalil Mohamed, Eman Abdullah Alshehri, Hayam Elshazly, Hatem A. Elshabrawy, Dina hamed
Acta Parasitologica.2025;[Epub] CrossRef
Characterization of a novel invasive virulence of chymotrypsin-like elastase family member 2A from Trichinella spiralis
Xin Guo, Xin Zhuo Zhang, Yao Zhang, Ru Zhang, Shao Rong Long, Ruo Dan Liu, Jing Cui, Zhong Quan Wang
Acta Tropica.2025; 270: 107803. CrossRef
Paying attention to attention: High attention sites as indicators of protein family and function in language models
Gowri Nayar, Alp Tartici, Russ B. Altman, Serdar Bozdag
PLOS Computational Biology.2025; 21(9): e1013424. CrossRef
Regulatory and coding changes underlying development and host detection in vertebrate-parasitizing blowflies
Pedro Mariano-Martins, Diniz Lima Ferreira, Vanessa Araujo Soares da Cunha, Carolina Kurotusch Canettieri, Letícia Chiara Baldassio de Paula, Tatiana Teixeira Torres
International Journal for Parasitology.2025;[Epub] CrossRef
Trichinella spiralis serine protease mediates larval invasion of gut epithelium via binding to CK8 and activating RhoA/ROCK1 pathway
Wen Wen Zheng, Xin Zhuo Zhang, Pei Kun Cong, Ru Zhang, Shao Rong Long, Xi Zhang, Ruo Dan Liu, Zhong Quan Wang, Jing Cui, Feng Xue
PLOS Neglected Tropical Diseases.2025; 19(11): e0013725. CrossRef
Host-parasite interactions: a study on the pathogenicity of different Mesanophrys sp. densities and hemocytes-mediated parasitic resistance of swimming crabs (Portunus trituberculatus)
Lujia Yang, Ruiling Zhou, Chunlin Wang, Xiao Xie, Suming Zhou, Fei Yin
Parasitology Research.2024;[Epub] CrossRef
Serine protease mediates Ovomermis sinensis‐inhibited host immune responses by inducing apoptosis: implications for successful parasitism and host mortality
Zhenlong Jiao, Mingming Chen, Wenjing Zhao, Yuanming Wu, Guo Guo
Pest Management Science.2024; 80(4): 1968. CrossRef
Application of a recombinant novel trypsin from Trichinella spiralis for serodiagnosis of trichinellosis
Lu Lu Han, Qi Qi Lu, Yang Li Li, Wen Wen Zheng, Pian Ren, Ruo Dan Liu, Jing Cui, Zhong Quan Wang
Parasites & Vectors.2024;[Epub] CrossRef
A novel Trichinella spiralis serine proteinase disrupted gut epithelial barrier and mediated larval invasion through binding to RACK1 and activating MAPK/ERK1/2 pathway
Yan Yan Song, Xin Zhuo Zhang, Bo Ning Wang, Yong Kang Cheng, Xin Guo, Xi Zhang, Shao Rong Long, Ruo Dan Liu, Zhong Quan Wang, Jing Cui, Krystyna Cwiklinski
PLOS Neglected Tropical Diseases.2024; 18(1): e0011872. CrossRef
Salmon louse labial gland enzymes: implications for host settlement and immune modulation
Helena Marie Doherty Midtbø, Christiane Eichner, Lars Are Hamre, Michael Dondrup, Linn Flesland, Kristoffer Helland Tysseland, Heidi Kongshaug, Andreas Borchel, Renate Hvidsten Skoge, Frank Nilsen, Aina-Cathrine Øvergård
Frontiers in Genetics.2024;[Epub] CrossRef
Moonlighting on the Fasciola hepatica tegument: Enolase, a glycolytic enzyme, interacts with the extracellular matrix and fibrinolytic system of the host
Eve O’Kelly, Krystyna Cwiklinski, Carolina De Marco Verissimo, Nichola Eliza Davies Calvani, Jesús López Corrales, Heather Jewhurst, Andrew Flaus, Richard Lalor, Judit Serrat, John P. Dalton, Javier González-Miguel, Gabriel Rinaldi
PLOS Neglected Tropical Diseases.2024; 18(8): e0012069. CrossRef
Excreted/Secreted 15-kDa Proteins and Serine Protease Peptides from Haemonchus contortus Act as Immune-Response Enhancers in Lambs
René Camas-Pereyra, Génesis Andrea Bautista-García, Gustavo Pérez-Anzúrez, Zaira Carolina Duran-Cortes, David Emanuel Reyes-Guerrero, Jocelyn Maza-Lopez, Agustín Olmedo-Juárez, María Eugenia López-Arellano
Pathogens.2024; 13(7): 604. CrossRef
Early diagnosis of Trichinella spiralis and Trichinella nativa: Expression of the serine protease gene at the invasive intestinal and muscular larva stages
Orken S. Akibekov, Aissarat M. Gajimuradova, Alfiya S. Syzdykova, Aibek Kh. Zhumalin, Fariza S. Zhagipar, Fabio Tosini, Zhannara Zh. Akanova, Nurtai N. Gubaidullin, Nasipkhan A. Askarova
Veterinary World.2024; : 2124. CrossRef
Trypsin, chymotrypsin and elastase in health and disease
Oladoyin Grace Famutimi, Victor Gbolahan Adebiyi, Bukola Grace Akinmolu, Omoniyi Vincent Dada, Isaac Olusanjo Adewale
Future Journal of Pharmaceutical Sciences.2024;[Epub] CrossRef
Protein profile of extracellular vesicles derived from adult Parascaris spp.
Vishnu Manikantan, Nichol E. Ripley, Martin K. Nielsen, Sriveny Dangoudoubiyam
Parasites & Vectors.2024;[Epub] CrossRef
In silico analysis of two Haemonchus spp. serine protease peptides (S28) and their immunomodulatory activity in vitro
René Camas-Pereyra, Génesis A. Bautista-García, Guillermina Avila, Yazmin Alcala-Canto, Jocelyn Maza-Lopez, David E. Reyes-Guerrero, Rosa Isabel Higuera-Piedrahita, María Eugenia López-Arellano
Molecular and Biochemical Parasitology.2023; 253: 111545. CrossRef
Proteases and their inhibitors involved in Schistosoma mansoni egg-host interaction revealed by comparative transcriptomics with Fasciola hepatica eggs
Kristyna Peterkova, Jiri Vorel, Jana Ilgova, Pavel Ostasov, Pavla Fajtova, Lukas Konecny, Marta Chanova, Martin Kasny, Martin Horn, Jan Dvorak
International Journal for Parasitology.2023; 53(5-6): 253. CrossRef
Secreted peptidases contribute to virulence of fish pathogen Flavobacterium columnare
Nicole C. Thunes, Haitham H. Mohammed, Jason P. Evenhuis, Ryan S. Lipscomb, David Pérez-Pascual, Rebecca J. Stevick, Clayton Birkett, Rachel A. Conrad, Jean-Marc Ghigo, Mark J. McBride
Frontiers in Cellular and Infection Microbiology.2023;[Epub] CrossRef
Biological control 2.0: Use of nematophagous fungi enzymes for nematode control
Filippe Elias de Freitas Soares, Juliana Marques Ferreira, Hugo Leonardo André Genier, Laith Khalil Tawfeeq Al-Ani, Liliana Aguilar-Marcelino
Journal of Natural Pesticide Research.2023; 4: 100025. CrossRef
In vitro knockdown of TsDNase II-7 suppresses Trichinella spiralis invasion into the host’s intestinal epithelial cells
Jing Wang, Xuemin Jin, Chengyao Li, Xinhui Chen, Yanfeng Li, Mingyuan Liu, Xiaolei Liu, Jing Ding, Pamela Marie Pennington
PLOS Neglected Tropical Diseases.2023; 17(6): e0011323. CrossRef
An insight into the functional genomics and species classification of Eudiplozoon nipponicum (Monogenea, Diplozoidae), a haematophagous parasite of the common carp Cyprinus carpio
Jiří Vorel, Nikol Kmentová, Christoph Hahn, Petr Bureš, Martin Kašný
BMC Genomics.2023;[Epub] CrossRef
The gut microbiota contributes to changes in the host immune response induced by Trichinella spiralis
Chengyao Li, Yi Liu, Xiaolei Liu, Xue Bai, Xuemin Jin, Fengyan Xu, Hong Chen, Yuanyuan Zhang, Isabelle Vallee, Mingyuan Liu, Yong Yang, Krystyna Cwiklinski
PLOS Neglected Tropical Diseases.2023; 17(8): e0011479. CrossRef
Molecular characterization of a novel serine proteinase from Trichinella spiralis and its participation in larval invasion of gut epithelium
Yan Yan Song, Xin Zhuo Zhang, Bo Ning Wang, Min Min Weng, Zhao Yu Zhang, Xin Guo, Xi Zhang, Zhong Quan Wang, Jing Cui, jong-Yil Chai
PLOS Neglected Tropical Diseases.2023; 17(9): e0011629. CrossRef
Oral immunization with attenuated Salmonella encoding an elastase elicits protective immunity against Trichinella spiralis infection
Xin Zhuo Zhang, Wen Wen Yue, Sheng Jie Bai, Hui Nan Hao, Yan Yan Song, Shao Rong Long, Ruo Dan Liu, Jing Cui, Zhong Quan Wang
Acta Tropica.2022; 226: 106263. CrossRef
Comparative transcriptome profiles of Schistosoma japonicum larval stages: Implications for parasite biology and host invasion
Shaoyun Cheng, Bingkuan Zhu, Fang Luo, Xiying Lin, Chengsong Sun, Yanmin You, Cun Yi, Bin Xu, Jipeng Wang, Yan Lu, Wei Hu, James Cotton
PLOS Neglected Tropical Diseases.2022; 16(1): e0009889. CrossRef
Characterization of the genome and serine protease of a novel Bacillus subtilis isolate
Zahoor Khan, Maryam Shafique, Faizan Saleem, M. Kamran Azim, Nusrat Jabeen, Sehar Afshan Naz
Antonie van Leeuwenhoek.2022; 115(2): 281. CrossRef
Functional Diversity of the Excretory/Secretory Proteins of Nematode Parasites
Paritosh Joshi, Prasanta Kumar K. Mishra
Acta Parasitologica.2022; 67(2): 619. CrossRef
Proteomic Profiling and In Silico Characterization of the Secretome of Anisakis simplex Sensu Stricto L3 Larvae
Maciej Kochanowski, Joanna Dąbrowska, Mirosław Różycki, Jacek Sroka, Jacek Karamon, Aneta Bełcik, Weronika Korpysa-Dzirba, Tomasz Cencek
Pathogens.2022; 11(2): 246. CrossRef
Transcriptomic Analysis of Steinernema Nematodes Highlights Metabolic Costs Associated to Xenorhabdus Endosymbiont Association and Rearing Conditions
Emilie Lefoulon, John G. McMullen, S. Patricia Stock
Frontiers in Physiology.2022;[Epub] CrossRef
Proteases secreted by Trichinella spiralis intestinal infective larvae damage the junctions of the intestinal epithelial cell monolayer and mediate larval invasion
Yan Yan Song, Qi Qi Lu, Lu Lu Han, Shu Wei Yan, Xin Zhuo Zhang, Ruo Dan Liu, Shao Rong Long, Jing Cui, Zhong Quan Wang
Veterinary Research.2022;[Epub] CrossRef
Proteomic Analysis of Plasma-Derived Extracellular Vesicles From Mice With Echinococcus granulosus at Different Infection Stages and Their Immunomodulatory Functions
Chunli Shi, Xiaojing Zhou, Wenjuan Yang, Jianwen Wu, Min Bai, Ying Zhang, Wei Zhao, Hui Yang, Atsushi Nagai, Mei Yin, Xiaoping Gao, Shuqin Ding, Jiaqing Zhao
Frontiers in Cellular and Infection Microbiology.2022;[Epub] CrossRef
Tandem Mass Tagging (TMT) Reveals Tissue-Specific Proteome of L4 Larvae of Anisakis simplex s. s.: Enzymes of Energy and/or Carbohydrate Metabolism as Potential Drug Targets in Anisakiasis
Robert Stryiński, Jesús Mateos, Mónica Carrera, Jan Paweł Jastrzębski, Iwona Bogacka, Elżbieta Łopieńska-Biernat
International Journal of Molecular Sciences.2022; 23(8): 4336. CrossRef
Novel Inhibitors and Activity-Based Probes Targeting Trypsin-Like Serine Proteases
Timothy E. G. Ferguson, James A. Reihill, S. Lorraine Martin, Brian Walker
Frontiers in Chemistry.2022;[Epub] CrossRef
Transcriptomic and proteomic profiling of peptidase expression in Fasciola hepatica eggs developing at host’s body temperature
Jana Ilgová, Jiří Vorel, Pavel Roudnický, Lucie Škorpíková, Martin Horn, Martin Kašný
Scientific Reports.2022;[Epub] CrossRef
Trichinella britovi recombinant proteins produced in Pichia pastoris expression system for specific IgG antibody detection in the sera of mice and pigs infected with Trichinella spp.
Sylwia Grzelak, Justyna Bień-Kalinowska, Anna Stachyra
Experimental Parasitology.2022; 242: 108386. CrossRef
A ShK-like Domain from Steinernema carpocapsae with Bioinsecticidal Potential
Jorge Frias, Duarte Toubarro, Gro Elin Kjæreng Bjerga, Pål Puntervoll, João B. Vicente, Rui L. Reis, Nelson Simões
Toxins.2022; 14(11): 754. CrossRef
Bioguided isolation of N-malonyl-(+)-tryptophan from the fruit of Pithecellobium dulce (Roxb.) Benth. that showed high activity against Hymenolepis nana
Gabriela López-Angulo, Sara Elizabeth Verdugo-Gaxiola, Julio Montes-Avila, Sylvia Páz Díaz-Camacho, Valentín Miranda-Soto, Nancy Yareli Salazar-Salas, Francisco Delgado-Vargas
Natural Product Research.2021; 35(4): 593. CrossRef
A putative lysozyme and serine carboxypeptidase from Heterorhabditis bacteriophora show differential virulence capacities in Drosophila melanogaster
Eric Kenney, Amulya Yaparla, John M. Hawdon, Damien M. O’ Halloran, Leon Grayfer, Ioannis Eleftherianos
Developmental & Comparative Immunology.2021; 114: 103820. CrossRef
A critical review on marine serine protease and its inhibitors: A new wave of drugs?
Noora Barzkar, Zahoor Khan, Saeid Tamadoni Jahromi, Sajjad Pourmozaffar, Mohsen Gozari, Reza Nahavandi
International Journal of Biological Macromolecules.2021; 170: 674. CrossRef
Proteomic analysis of hydrolytic proteases in excretory/secretory proteins from Trichinella spiralis intestinal infective larvae using zymography combined with shotgun LC-MS/MS approach
Hua Nan Ren, Tong Xu Zhuo, Sheng Jie Bai, Ying Bai, Xiang Yuan Sun, Ruo Dan Liu, Shao Rong Long, Jing Cui, Zhong Quan Wang
Acta Tropica.2021; 216: 105825. CrossRef
Disruption of Epithelial Barrier of Caco-2 Cell Monolayers by Excretory Secretory Products of Trichinella spiralis Might Be Related to Serine Protease
Chengyao Li, Xue Bai, Xiaolei Liu, Yuanyuan Zhang, Lei Liu, Lixiao Zhang, Fengyan Xu, Yong Yang, Mingyuan Liu
Frontiers in Microbiology.2021;[Epub] CrossRef
Immune Protection of a Helminth Protein in the DSS-Induced Colitis Model in Mice
Shao Rong Long, Ruo Dan Liu, Deepak Vijaya Kumar, Zhong Quan Wang, Chien-Wen Su
Frontiers in Immunology.2021;[Epub] CrossRef
The immune protection induced by a serine protease from the Trichinella spiralis adult against Trichinella spiralis infection in pigs
Daoxiu Xu, Xue Bai, Jing Xu, Xuelin Wang, Zijian Dong, Wenjie Shi, Fengyan Xu, Yanfeng Li, Mingyuan Liu, Xiaolei Liu, Hernando A. del Portillo
PLOS Neglected Tropical Diseases.2021; 15(5): e0009408. CrossRef
Spatial expression pattern of serine proteases in the blood fluke Schistosoma mansoni determined by fluorescence RNA in situ hybridization
Lenka Ulrychová, Pavel Ostašov, Marta Chanová, Michael Mareš, Martin Horn, Jan Dvořák
Parasites & Vectors.2021;[Epub] CrossRef
Characterization of a chymotrypsin-like enzyme from Trichinella spiralis and its facilitation of larva penetration into the host's enteral epithelial cells
Jia Xu, Ruo Dan Liu, Shao Rong Long, Yan Yan Song, Peng Jiang, Xi Zhang, Jing Cui, Zhong Quan Wang
Research in Veterinary Science.2020; 128: 1. CrossRef
In silico design of a T-cell epitope vaccine candidate for parasitic helminth infection
Ayat Zawawi, Ruth Forman, Hannah Smith, Iris Mair, Murtala Jibril, Munirah H. Albaqshi, Andrew Brass, Jeremy P. Derrick, Kathryn J. Else, Maria Elena Bottazzi
PLOS Pathogens.2020; 16(3): e1008243. CrossRef
Effect of recombinant serine protease from adult stage of Trichinella spiralis on TNBS-induced experimental colitis in mice
Jianda Pang, Jing Ding, Lixiao Zhang, Yuanyuan Zhang, Yaming Yang, Xue Bai, Xiaolei Liu, Xuemin Jin, Heng Guo, Yong Yang, Mingyuan Liu
International Immunopharmacology.2020; 86: 106699. CrossRef
Binding of elastase-1 and enterocytes facilitates Trichinella spiralis larval intrusion of the host's intestinal epithelium
Chen Xi Hu, Jie Zeng, Da Qi Yang, Xin Yue, Ruo Dan Liu, Shao Rong Long, Xi Zhang, Peng Jiang, Jing Cui, Zhong Quan Wang
Acta Tropica.2020; 211: 105592. CrossRef
Effect of recombinant serine protease from newborn larval stage of Trichinella spiralis on 2,4,6-trinitrobenzene sulfonic acid-induced experimental colitis in mice
Zheng Qu, Xuemin Jin, Yang Wang, Yaming Yang, Yang Li, Xue Bai, Yong Yang, Ning Xu, Xuelin Wang, Mingyuan Liu
Acta Tropica.2020; 211: 105553. CrossRef
Anisakis simplex products impair intestinal epithelial barrier function and occludin and zonula occludens-1 localisation in differentiated Caco-2 cells
Noelia Carballeda-Sangiao, Isabel Sánchez-Alonso, Alfonso Navas, Susana C. Arcos, Pilar Fernández de Palencia, Mercedes Careche, Miguel González-Muñoz, Luisa Magalhães
PLOS Neglected Tropical Diseases.2020; 14(7): e0008462. CrossRef
Comparative genomics and transcriptomics of 4 Paragonimus species provide insights into lung fluke parasitism and pathogenesis
Bruce A Rosa, Young-Jun Choi, Samantha N McNulty, Hyeim Jung, John Martin, Takeshi Agatsuma, Hiromu Sugiyama, Thanh Hoa Le, Pham Ngoc Doanh, Wanchai Maleewong, David Blair, Paul J Brindley, Peter U Fischer, Makedonka Mitreva
GigaScience.2020;[Epub] CrossRef
Vaccination of Mice with a Novel Trypsin from Trichinella spiralis Elicits the Immune Protection against Larval Challenge
Yao Zhang, Jie Zeng, Yan Yan Song, Shao Rong Long, Ruo Dan Liu, Peng Jiang, Xi Zhang, Jing Cui, Zhong Quan Wang
Vaccines.2020; 8(3): 437. CrossRef
Molecular cloning and characterization of a novel peptidase from Trichinella spiralis and protective immunity elicited by the peptidase in BALB/c mice
Jun Jun Lei, Yuan Yuan Hu, Fang Liu, Shu Wei Yan, Ruo Dan Liu, Shao Rong Long, Peng Jiang, Jing Cui, Zhong Quan Wang
Veterinary Research.2020;[Epub] CrossRef
Immunomodulation and Immune Escape Strategies of Gastrointestinal Helminths and Schistosomes
Marie Wiedemann, David Voehringer
Frontiers in Immunology.2020;[Epub] CrossRef
Proteases and pseudoproteases in parasitic arthropods of clinical importance
Deepani Darshika Fernando, Katja Fischer
The FEBS Journal.2020; 287(19): 4284. CrossRef
Molecular characterization of a Trichinella spiralis serine proteinase
Xin Yue, Xiang Yuan Sun, Fang Liu, Chen Xi Hu, Ying Bai, Qi Da Yang, Ruo Dan Liu, Xi Zhang, Jing Cui, Zhong Quan Wang
Veterinary Research.2020;[Epub] CrossRef
Activity of serine proteases from Fasciola hepatica eggs in relation to pH and temperature
L. Kianifard, M. Yakhchali, M. Imani
BULGARIAN JOURNAL OF VETERINARY MEDICINE.2020; 23(3): 350. CrossRef
Host Immunity and Inflammation to Pulmonary Helminth Infections
Jill E. Weatherhead, Pedro Gazzinelli-Guimaraes, John M. Knight, Ricardo Fujiwara, Peter J. Hotez, Maria Elena Bottazzi, David B. Corry
Frontiers in Immunology.2020;[Epub] CrossRef
Intranasal immunization with recombinant Trichinella spiralis serine protease elicits protective immunity in BALB/c mice
Ge Ge Sun, Jun Jun Lei, Hua Nan Ren, Yao Zhang, Kai Xia Guo, Shao Rong Long, Ruo Dan Liu, Peng Jiang, Zhong Quan Wang, Jing Cui
Experimental Parasitology.2019; 201: 1. CrossRef
Cloning, expression and characterization of a novel alkaline serine protease gene from native Iranian Bacillus sp.; a producer of protease for use in livestock
Ahmadreza Ariyaei, Ayoub Farhadi, Fatemeh Moradian, Ghodrat Rahimi Mianji
Gene.2019; 693: 10. CrossRef
Exploration of extracellular vesicles from Ascaris suum provides evidence of parasite–host cross talk
Eline P. Hansen, Bastian Fromm, Sidsel D. Andersen, Antonio Marcilla, Kasper L. Andersen, Anne Borup, Andrew R. Williams, Aaron R. Jex, Robin B. Gasser, Neil D. Young, Ross S. Hall, Allan Stensballe, Vladimir Ovchinnikov, Yan Yan, Merete Fredholm, Stig M.
Journal of Extracellular Vesicles.2019;[Epub] CrossRef
Hybrid Assembly of the Genome of the Entomopathogenic Nematode Steinernema carpocapsae Identifies the X-Chromosome
Lorrayne Serra, Marissa Macchietto, Aide Macias-Muñoz, Cassandra Joan McGill, Isaryhia Maya Rodriguez, Bryan Rodriguez, Rabi Murad, Ali Mortazavi
G3 Genes|Genomes|Genetics.2019; 9(8): 2687. CrossRef
Complex insight on microanatomy of larval “human broad tapeworm” Dibothriocephalus latus (Cestoda: Diphyllobothriidea)
Daniel Barčák, Aneta Yoneva, Hana Sehadová, Mikuláš Oros, Andrea Gustinelli, Roman Kuchta
Parasites & Vectors.2019;[Epub] CrossRef
Screening and verification for proteins that interact with leucine aminopeptidase of Taenia pisiformis using a yeast two-hybrid system
Shaohua Zhang
Parasitology Research.2019; 118(12): 3387. CrossRef
Proteases and protease inhibitors in infectious diseases
Ayodeji A. Agbowuro, Wilhelmina M. Huston, Allan B. Gamble, Joel D. A. Tyndall
Medicinal Research Reviews.2018; 38(4): 1295. CrossRef
Molecular cloning and characterization of leucine aminopeptidase gene from Taenia pisiformis
Shaohua Zhang, Xuepeng Cai, Xuenong Luo, Shuai Wang, Aijiang Guo, Junling Hou, Run Wu
Experimental Parasitology.2018; 186: 1. CrossRef
SmSP2: A serine protease secreted by the blood fluke pathogen Schistosoma mansoni with anti-hemostatic properties
Adrian Leontovyč, Lenka Ulrychová, Anthony J. O’Donoghue, Jiří Vondrášek, Lucie Marešová, Martin Hubálek, Pavla Fajtová, Marta Chanová, Zhenze Jiang, Charles S. Craik, Conor R. Caffrey, Michael Mareš, Jan Dvořák, Martin Horn, Robert M. Greenberg
PLOS Neglected Tropical Diseases.2018; 12(4): e0006446. CrossRef
Characterization of a Trichinella spiralis putative serine protease. Study of its potential as sero-diagnostic tool
Ge Ge Sun, Yan Yan Song, Peng Jiang, Hua Na Ren, Shu Wei Yan, Yue Han, Ruo Dan Liu, Xi Zhang, Zhong Quan Wang, Jing Cui, Edoardo Pozio
PLOS Neglected Tropical Diseases.2018; 12(5): e0006485. CrossRef
Trichuris muris whey acidic protein induces type 2 protective immunity against whipworm
Neima Briggs, Junfei Wei, Leroy Versteeg, Bin Zhan, Brian Keegan, Ashish Damania, Jeroen Pollet, Kelly S. Hayes, Coreen Beaumier, Christopher A. Seid, Jamie Leong, Richard K. Grencis, Maria Elena Bottazzi, K. Jagannadha Sastry, Peter J. Hotez, Edward Mitr
PLOS Pathogens.2018; 14(8): e1007273. CrossRef
The coagulation system helps control infection caused by the ciliate parasite Philasterides dicentrarchi in the turbot Scophthalmus maximus (L.)
V. Blanco-Abad, M. Noia, A. Valle, F. Fontenla, I. Folgueira, A.P. De Felipe, P. Pereiro, J. Leiro, J. Lamas
Developmental & Comparative Immunology.2018; 87: 147. CrossRef
Molecular characterization of a putative serine protease from Trichinella spiralis and its elicited immune protection
Ge Ge Sun, Hua Nan Ren, Ruo Dan Liu, Yan Yan Song, Xin Qi, Chen Xi Hu, Fan Yang, Peng Jiang, Xi Zhang, Zhong Quan Wang, Jing Cui
Veterinary Research.2018;[Epub] CrossRef
Silent Witness: Dual-Species Transcriptomics Reveals Epithelial Immunological Quiescence to Helminth Larval Encounter and Fostered Larval Development
Friederike Ebner, Mathias Kuhring, Aleksandar Radonić, Ankur Midha, Bernhard Y. Renard, Susanne Hartmann
Frontiers in Immunology.2018;[Epub] CrossRef
Protective immunity against Trichinella spiralis in mice elicited by oral vaccination with attenuated Salmonella-delivered TsSP1.2 DNA
Jie Feng Li, Kai Xia Guo, Xin Qi, Jun Jun Lei, Yue Han, Shu Wei Yan, Peng Jiang, Chuan Yu, Xiang Chao Cheng, Zhong Quan Wang, Jing Cui
Veterinary Research.2018;[Epub] CrossRef
Plasminogen-binding proteins as an evasion mechanism of the host’s innate immunity in infectious diseases
Dolores A. Ayón-Núñez, Gladis Fragoso, Raúl J. Bobes, Juan P. Laclette
Bioscience Reports.2018;[Epub] CrossRef
Editing the genome of Aphanomyces invadans using CRISPR/Cas9
Muhammad Majeed, Hatem Soliman, Gokhlesh Kumar, Mansour El-Matbouli, Mona Saleh
Parasites & Vectors.2018;[Epub] CrossRef
Activity profiling of peptidases in Angiostrongylus costaricensis first-stage larvae and adult worms
Karina M. Rebello, James H. McKerrow, Ester M. Mota, Anthony J. O´Donoghue, Ana Gisele C. Neves-Ferreira, John Pius Dalton
PLOS Neglected Tropical Diseases.2018; 12(10): e0006923. CrossRef
ВЛИЯНИЕ ЗАРАЖЕНИЯ ЦЕСТОДОЙ PROTEOCEPHALUS TORULOSUS BATSCH, 1786 НА АКТИВНОСТЬ ФЕРМЕНТОВ В КИШЕЧНИКЕ СИНЦА (BALLERUS BALLERUS L.), "Паразитология"
Т.В. Фролова, Г.И. Извекова
Паразитология.2018; (4): 292. CrossRef
Molecular characterization of a 31 kDa protein from Trichinella spiralis and its induced immune protection in BALB/c mice
Hua Nan Ren, Kai Xia Guo, Yao Zhang, Ge Ge Sun, Ruo Dan Liu, Peng Jiang, Xi Zhang, Li Wang, Jing Cui, Zhong Quan Wang
Parasites & Vectors.2018;[Epub] CrossRef
Recent advances in proteomic applications for schistosomiasis research: potential clinical impact
Javier Sotillo, Denise Doolan, Alex Loukas
Expert Review of Proteomics.2017; 14(2): 171. CrossRef
A critical review on serine protease: Key immune manipulator and pathology mediator
S. Patel
Allergologia et Immunopathologia.2017; 45(6): 579. CrossRef
Proteolytic enzymes and their inhibitors in cestodes
G. I. Izvekova, T. V. Frolova
Biology Bulletin Reviews.2017; 7(2): 150. CrossRef
Comparative proteomics of hydatid fluids from two Echinococcus multilocularis isolates
Karina M. Monteiro, Karina R. Lorenzatto, Jeferson C. de Lima, Guilherme B. dos Santos, Sabine Förster, Gabriela P. Paludo, Paulo C. Carvalho, Klaus Brehm, Henrique B. Ferreira
Journal of Proteomics.2017; 162: 40. CrossRef
Proteomic Analysis of Trichinella spiralis Adult Worm Excretory-Secretory Proteins Recognized by Sera of Patients with Early Trichinellosis
Zhong Q. Wang, Ruo D. Liu, Ge G. Sun, Yan Y. Song, Peng Jiang, Xi Zhang, Jing Cui
Frontiers in Microbiology.2017;[Epub] CrossRef
Immunoproteomic analysis of the excretory-secretory products of Trichinella pseudospiralis adult worms and newborn larvae
Yang Wang, Xue Bai, Haichao Zhu, Xuelin Wang, Haining Shi, Bin Tang, Pascal Boireau, Xuepeng Cai, Xuenong Luo, Mingyuan Liu, Xiaolei Liu
Parasites & Vectors.2017;[Epub] CrossRef
Effects of ionic liquids on the hydrolysis of casein by lumbrokinase
Yunchang Fan, Xing Dong, Yingying Zhong, Jing Li, Juan Miao, Shaofeng Hua, Yan Li, Boyu Cheng, Wenqiong Chen
Biochemical Engineering Journal.2016; 109: 35. CrossRef
Carbonic anhydrase enzyme as a potential therapeutic target for experimental trichinellosis
Abeer E. Saad, Dalia S. Ashour, Dina M. Abou Rayia, Asmaa E. Bedeer
Parasitology Research.2016; 115(6): 2331. CrossRef
Integrated Activity and Genetic Profiling of Secreted Peptidases in Cryptococcus neoformans Reveals an Aspartyl Peptidase Required for Low pH Survival and Virulence
Starlynn C. Clarke, Phillip A. Dumesic, Christina M. Homer, Anthony J. O’Donoghue, Florencia La Greca, Lenka Pallova, Pavel Majer, Hiten D. Madhani, Charles S. Craik, Robin Charles May
PLOS Pathogens.2016; 12(12): e1006051. CrossRef

22,394 View
298 Download
91 Web of Science
Crossref

Original Article

Modulation of Antibody Responses against Gnathostoma spinigerum in Mice Immunized with Crude Antigen Formulated in CpG Oligonucleotide and Montanide ISA720: Pewpan M. Intapan, Chakrit Hirunpetcharat, Churairat Kularbkaew, Wiboonchai Yutanawiboonchai, Penchom Janwan, Wanchai Maleewong; Korean J Parasitol 2013;51(6):637-644.
Published online December 31, 2013; DOI: https://doi.org/10.3347/kjp.2013.51.6.637

Abstract
PDF

This study aimed to investigate the antibody responses in mice immunized with Gnathostoma spinigerum crude antigen (GsAg) incorporated with the combined adjuvant, a synthetic oligonucleotide containing unmethylated CpG motif (CpG ODN 1826) and a stable water in oil emulsion (Montanide ISA720). Mice immunized with GsAg and combined adjuvant produced all antibody classes and subclasses to GsAg except IgA. IgG2a/2b/3 but not IgG1 subclasses were enhanced by immunization with CpG ODN 1826 when compared with the control groups immunized with non-CpG ODN and Montanide ISA or only with Montanide ISA, suggesting a biased induction of a Th1-type response by CpG ODN. After challenge infection with live G. spinigerum larvae, the levels of IgG2a/2b/3 antibody subclasses decreased immediately and continuously, while the IgG1 subclass remained at high levels. This also corresponded to a continuous decrease of the IgG2a/IgG1 ratio after infection. Only IgM and IgG1 antibodies, but not IgG2a/2b/3, were significantly produced in adjuvant control groups after infection. These findings suggest that G. spinigerum infection potently induces a Th2-type biased response.

Citations

Citations to this article as recorded by

Evaluation of immunodiagnostic tests for human gnathostomiasis using different antigen preparations of Gnathostoma spinigerum larvae against IgE, IgM, IgG, IgG1‐4 and IgG1 patterns of post‐treated patients
Issariya Ieamsuwan, Dorn Watthanakulpanich, Urai Chaisri, Poom Adisakwattana, Paron Dekumyoy
Tropical Medicine & International Health.2021; 26(12): 1634. CrossRef

8,753 View
86 Download
Crossref

Mini Review

Mucosal immunity against parasitic gastrointestinal nematodes: Denis Nnabuike Onah, Yukifumi Nawa; Korean J Parasitol 2000;38(4):209-236.
Published online December 31, 2000; DOI: https://doi.org/10.3347/kjp.2000.38.4.209

Abstract
PDF

The last two decades witnessed significant advances in the efforts of immunoparasitologists to elucidate the nature and role of the host mucosal defence mechanisms against intestinal nematode parasites. Aided by recent advances in basic immunology and biotechnology with the concomitant development of well defined laboratory models of infection, immunoparasitologists have more precisely analyzed and defined the different immune effector mechanisms during the infection; resulting in great improvement in our current knowledge and understanding of protective immunity against gastrointestinal (GI) nematode parasites. Much of this current understanding comes from experimental studies in laboratory rodents, which have been used as models of livestock and human GI nematode infections. These rodent studies, which have concentrated on Heligmosomoides polygyrus, Nippostrongylus brasiliensis, Strongyloides ratti/S. venezuelensis, Trichinella spiralis and Trichuris muris infections in mice and rats, have helped in defining the types of T cell responses that regulate effector mechanisms and the effector mechanisms responsible for worm expulsion. In addition, these studies bear indications that traditionally accepted mechanisms of resistance such as eosinophilia and IgE responses may not play as important roles in protection as were previously conceived. In this review, we shall, from these rodent studies, attempt an overview of the mucosal and other effector responses against intestinal nematode parasites beginning with the indices of immune protection as a model of the protective immune responses that may occur in animals and man.

Citations

Citations to this article as recorded by

Mucosal Immunity of Major Gastrointestinal Nematode Infections in Small Ruminants Can Be Harnessed to Develop New Prevention Strategies
P. G. Ashani S. Palkumbura, Thilini A. N. Mahakapuge, R. R. M. K. Kavindra Wijesundera, Viskam Wijewardana, Richard Thiga Kangethe, R. P. V. Jayanthe Rajapakse
International Journal of Molecular Sciences.2024; 25(3): 1409. CrossRef
Goats are more susceptible to Haemonchus contortus infection than sheep under similar experimental settings
Desta Risa, Gezahegne Mamo, Hika Waktole, Geremew Haile, Getachew Terefe
Scientific Reports.2024;[Epub] CrossRef
Chronic Strongyloides stercoralis infection increases presence of the Ruminococcus torques group in the gut and alters the microbial proteome
Na T. D. Tran, Apisit Chaidee, Achirawit Surapinit, Manachai Yingklang, Sitiruk Roytrakul, Sawanya Charoenlappanit, Porntip Pinlaor, Nuttanan Hongsrichan, Sirirat Anutrakulchai, Ubon Cha’on, Somchai Pinlaor
Scientific Reports.2023;[Epub] CrossRef
Mucosal Vaccination With Recombinant Tm-WAP49 Protein Induces Protective Humoral and Cellular Immunity Against Experimental Trichuriasis in AKR Mice
Junfei Wei, Venkatesh L. Hegde, Ananta V. Yanamandra, Madison P. O’Hara, Brian Keegan, Kathryn M. Jones, Ulrich Strych, Maria Elena Bottazzi, Bin Zhan, K. Jagannadha Sastry, Peter J. Hotez
Frontiers in Immunology.2022;[Epub] CrossRef
Resistance mesenteric arteries display hypercontractility in the resolution time of Strongyloides venezuelensis infection
Vanessa Dela Justina, Loyane Almeida Gama, Tatiane Schönholzer, Alecsander F. Bressan, Victor Vitorino Lima, Madileine F. Americo, Fernanda R. Giachini
Experimental Parasitology.2021; 222: 108078. CrossRef
The latest FAD – Faecal antibody detection in cattle. Protocol and results from three UK beef farms naturally infected with gastrointestinal nematodes
A. S. Cooke, K. A. Watt, E. R. Morgan, J. A. J. Dungait
Parasitology.2019; 146(1): 89. CrossRef
Globule Leukocytes and Other Mast Cells in the Mouse Intestine
Peter Vogel, Laura Janke, David M. Gravano, Meifen Lu, Deepali V. Sawant, Dorothy Bush, E Shuyu, Dario A. A. Vignali, Asha Pillai, Jerold E. Rehg
Veterinary Pathology.2018; 55(1): 76. CrossRef
Salmon louse rhabdoviruses: Impact on louse development and transcription of selected Atlantic salmon immune genes
Aina-Cathrine Øvergård, Lars Are Hamre, Sindre Grotmol, Frank Nilsen
Developmental & Comparative Immunology.2018; 86: 86. CrossRef
Inducible nitric oxide synthase controls experimental Strongyloides infection
Rosângela Maria Rodrigues, Ana Lúcia Ribeiro Gonçalves, Neide Maria Silva, Cristina Ribeiro de Barros Cardoso, Natália Rodrigues Araújo, Loyane Bertagnolli Coutinho, Ronaldo Alves, Marlene Tiduko Ueta, Julia Maria Costa‐Cruz
Parasite Immunology.2018;[Epub] CrossRef
The role of IL-33/ST2, IL-4, and eosinophils on the airway hyperresponsiveness induced by Strongyloides venezuelensis in BALB/c mice
Emilia Souza Araujo, Cintia Aparecida de Jesus Pereira, Ana Terezinha de Moura Pereira, João Marcelo Peixoto Moreira, Michelle Carvalho de Rezende, Jailza Lima Rodrigues, Mauro Martins Teixeira, Deborah Negrão-Corrêa
Parasitology Research.2016; 115(8): 3107. CrossRef
IL-22 Restrains Tapeworm-Mediated Protection against Experimental Colitis via Regulation of IL-25 Expression
José L. Reyes, Maria R. Fernando, Fernando Lopes, Gabriella Leung, Nicole L. Mancini, Chelsea E. Matisz, Arthur Wang, Derek M. McKay, Debroski R. Herbert
PLOS Pathogens.2016; 12(4): e1005481. CrossRef
Strongyloides stercoralisInfection in Alcoholic Patients
Marcia C. A. Teixeira, Flavia T. F. Pacheco, Joelma N. Souza, Mônica L. S. Silva, Elizabete J. Inês, Neci M. Soares
BioMed Research International.2016; 2016: 1. CrossRef
Partially Protective Immunity Induced by a 20 kDa Protein Secreted by Trichinella spiralis Stichocytes
Kuo Bi, Jing Yang, Lei Wang, Yuan Gu, Bin Zhan, Xinping Zhu, Érika Martins Braga
PLOS ONE.2015; 10(8): e0136189. CrossRef
Strongyloides stercoralis infection in marmosets: replication of complicated and uncomplicated human disease and parasite biology
Vitor Luís Tenório Mati, Pedro Raso, Alan Lane de Melo
Parasites & Vectors.2014;[Epub] CrossRef
Strongyloides cebus(Nematoda: Strongyloididae) inLagothrix cana(Primates: Atelidae) from the Brazilian Amazon: Aspects of Clinical Presentation, Anatomopathology, Treatment, and Parasitic Biology
Vitor Luís Tenório Mati, Francisco Carlos Ferreira Junior, Hudson Alves Pinto, Alan Lane de Melo
Journal of Parasitology.2013; 99(6): 1009. CrossRef
Increased susceptibility to Strongyloides venezuelensis infection is related to the parasite load and absence of major histocompatibility complex (MHC) class II molecules
Rosângela Maria Rodrigues, Cristina Ribeiro Cardoso, Ana Lúcia Ribeiro Gonçalves, Neide Maria Silva, Virgínia Massa, Ronaldo Alves, Marlene Tiduko Ueta, João Santana Silva, Julia Maria Costa-Cruz
Experimental Parasitology.2013; 135(3): 580. CrossRef
Intestinal mast cells and eosinophils in relation to Strongyloides ratti adult expulsion from the small and large intestines of rats
Y. SHINTOKU, T. KADOSAKA, E. KIMURA, H. TAKAGI, S. KONDO, M. ITOH
Parasitology.2013; 140(5): 626. CrossRef
Hymenolepis diminuta: Analysis of the expression of Toll-like receptor genes (TLR2 and TLR4) in the small and large intestines of rats
D.I. Kosik-Bogacka, A. Wojtkowiak-Giera, A. Kolasa, R. Salamatin, P.P. Jagodzinski, E. Wandurska-Nowak
Experimental Parasitology.2012; 130(3): 261. CrossRef
Iron deficiency reduces serum and in vitro secretion of interleukin-4 in mice independent of altered spleen cell proliferation
Solo R. Kuvibidila, Maria Velez, Renée Gardner, Kavitha Penugonda, Lawrance C. Chandra, Lolie Yu
Nutrition Research.2012; 32(2): 107. CrossRef
Immunological mechanisms involved in the protection against intestinal taeniosis elicited by oral immunization with Taenia solium calreticulin
Sonia Leon-Cabrera, Mayra Cruz-Rivera, Fela Mendlovic, Mirza Romero-Valdovinos, Gilberto Vaughan, Ana María Salazar, Guillermina Avila, Ana Flisser
Experimental Parasitology.2012; 132(3): 334. CrossRef
Hookworm virulence factors: making the most of the host
Maria V. Periago, Jeffrey M. Bethony
Microbes and Infection.2012; 14(15): 1451. CrossRef
Intraepithelial lymphocytes, goblet cells and VIP‐IR submucosal neurons of jejunum rats infected with Toxoplasma gondii
Débora M. G. Sant’Ana, Marcelo B. Góis, Jacqueline N. Zanoni, Aristeu V. da Silva, Cleverton J. T. da Silva, Eduardo J. A. Araújo
International Journal of Experimental Pathology.2012; 93(4): 279. CrossRef
Helminth infections: therapeutic potential in autoimmune disorders
M. EL‐MALKY, N. NABIH, M. HEDER, N. SAUDY, M. EL‐MAHDY
Parasite Immunology.2011; 33(11): 589. CrossRef
Strongyloides ratti:transplantation of adults recovered from the small intestine at different days after infection into the colon of naive and infection-primed Wistar rats, and the effect of antioxidant treatment on large intestinal parasitism
Y. SHINTOKU, H. TAKAGI, T. KADOSAKA, F. NAGAOKA, S. KONDO, M. ITOH, S. HONDA, E. KIMURA
Parasitology.2011; 138(8): 1053. CrossRef
Taenia solium: Immune response against oral or systemic immunization with purified recombinant calreticulin in mice
Salvador Fonseca-Coronado, Karina Ruiz-Tovar, Mayra Pérez-Tapia, Fela Mendlovic, Ana Flisser
Experimental Parasitology.2011; 127(1): 313. CrossRef
Taenia solium: current understanding of laboratory animal models of taeniosis
A. FLISSER, G. ÁVILA, P. MARAVILLA, F. MENDLOVIC, S. LEÓN-CABRERA, M. CRUZ-RIVERA, A. GARZA, B. GÓMEZ, L. AGUILAR, N. TERÁN, S. VELASCO, M. BENÍTEZ, D. E. JIMENEZ-GONZALEZ
Parasitology.2010; 137(3): 347. CrossRef
Regulation of immune responses toStrongyloides venezuelensischallenge after primary infection with different larvae doses
H. C. SCHILTER, A. T. M. PEREIRA, P. D. ESCHENAZI, A. FERNANDES, D. SHIM, A. L. S. SOUSA, M. M. TEIXEIRA, D. NEGRÃO-CORRÊA
Parasite Immunology.2010; 32(3): 184. CrossRef
Major histocompatibility complex (MHC) class II but not MHC class I molecules are required for efficient control of Strongyloides venezuelensis infection in mice
Rosângela M. Rodrigues, Neide M. Silva, Ana Lúcia R. Gonçalves, Cristina R. Cardoso, Ronaldo Alves, Flávia A. Gonçalves, Marcelo E. Beletti, Marlene T. Ueta, João S. Silva, Julia M. Costa‐Cruz
Immunology.2009;[Epub] CrossRef
Cd4+ T-cell-dependent Goblet Cell Proliferation and Expulsion of Gymnophalloides seoi from the Intestine of C57bl/6 Mice
Sang-Mee Guk, Jun-Haeng Lee, Hyo-Jin Kim, Won-Hee Kim, Eun-Hee Shin, Jong-Yil Chai
Journal of Parasitology.2009; 95(3): 581. CrossRef
The Immunological Effects of Electrolyzed Reduced Water on the Echinostoma hortense Infection in C57BL/6 Mice
Kyu Jae Lee, Dan Jin, Byung Soo Chang, Yung Chien Teng, Dong Heui Kim
Biological and Pharmaceutical Bulletin.2009; 32(3): 456. CrossRef
INCREASED INTESTINAL ENDOTOXIN ABSORPTION DURING ENTERIC NEMATODE BUT NOT PROTOZOAL INFECTIONS THROUGH A MAST CELL-MEDIATED MECHANISM
Ayman Samir Farid, Fumiko Jimi, Kyoko Inagaki-Ohara, Yoichiro Horii
Shock.2008; 29(6): 709. CrossRef
Immunolocalization and pathological alterations following Strongyloides venezuelensis infection in the lungs and the intestine of MHC class I or II deficient mice
A.L.R. Gonçalves, R.M. Rodrigues, N.M. Silva, F.A. Gonçalves, C.R. Cardoso, M.E. Beletti, M.T. Ueta, J.S. Silva, J.M. Costa-Cruz
Veterinary Parasitology.2008; 158(4): 319. CrossRef
Evaluation of the immune response against Strongyloides venezuelensis in antigen‐immunized or previously infected mice
A. FERNANDES, A. T. M. PEREIRA, P. D. ESCHENAZI, H. C. SCHILTER, A. L. S. SOUSA, M. M. TEIXEIRA, D. NEGRÃO‐CORRÊA
Parasite Immunology.2008; 30(3): 139. CrossRef
IL-4/IL-13 independent goblet cell hyperplasia in experimental helminth infections
Reece G Marillier, Chesney Michels, Elizabeth M Smith, Lizette CE Fick, Mosiuoa Leeto, Benjamin Dewals, William GC Horsnell, Frank Brombacher
BMC Immunology.2008;[Epub] CrossRef
Expulsion of the gastrointestinal cestode, Hymenolepis diminuta by tolerant rats: evidence for mediation by a Th2 type immune enhanced goblet cell hyperplasia, increased mucin production and secretion
R. A. WEBB, T. HOQUE, S. DIMAS
Parasite Immunology.2007; 29(1): 11. CrossRef
Density-dependent immune responses against the gastrointestinal nematode Strongyloides ratti
Colin Bleay, Clare P. Wilkes, Steve Paterson, Mark E. Viney
International Journal for Parasitology.2007; 37(13): 1501. CrossRef
Expression of IL-4 receptor on non-bone marrow-derived cells is necessary for the timely elimination of Strongyloides venezuelensis in mice, but not for intestinal IL-4 production
Deborah Negrão-Corrêa, Vanessa Pinho, Danielle G. Souza, Ana Terezinha M. Pereira, Adriana Fernandes, Karina Scheuermann, Adriano L.S. Souza, Mauro M. Teixeira
International Journal for Parasitology.2006; 36(10-11): 1185. CrossRef
Trichuris suis population dynamics following a primary experimental infection
Helene Kringel, Allan Roepstorff
Veterinary Parasitology.2006; 139(1-3): 132. CrossRef
Microcapsules formulated in the enteric coating copolymer Eudragit L100 as delivery systems for oral vaccination against infections by gastrointestinal nematode parasites
Maria A. Dea-Ayuela, Sara Rama-Iñiguez, S. Torrado-Santiago, F. Bolas-Fernandez
Journal of Drug Targeting.2006; 14(8): 567. CrossRef
Haemonchus contortus(Nematoda: Trichostrongylidae) infection in lambs elicits an unequivocal Th2 immune response
Caroline Lacroux, Thi Hai Chi Nguyen, Olivier Andreoletti, Françoise Prevot, Christelle Grisez, Jean-Paul Bergeaud, Lucas Gruner, Jean-Claude Brunel, Dominique Francois, Philippe Dorchies, Philippe Jacquiet
Veterinary Research.2006; 37(4): 607. CrossRef
Intestinal strongyloidiasis and hyperinfection syndrome
Raja S Vadlamudi, David S Chi, Guha Krishnaswamy
Clinical and Molecular Allergy.2006;[Epub] CrossRef
Haemonchus contortus egg excretion and female length reduction in sheep previously infected with Oestrus ovis (Diptera: Oestridae) larvae
G. Terefe, H.T. Yacob, C. Grisez, F. Prevot, E. Dumas, J.P. Bergeaud, Ph. Dorchies, H. Hoste, P. Jacquiet
Veterinary Parasitology.2005; 128(3-4): 271. CrossRef
Interactions between intrinsic and extrinsic mechanisms in a cyclic species: testosterone increases parasite infection in red grouse
Linzi J Seivwright, Stephen M Redpath, François Mougeot, Fiona Leckie, Peter J Hudson
Proceedings of the Royal Society B: Biological Sciences.2005; 272(1578): 2299. CrossRef
Separating Behavioral and Physiological Mechanisms in Testosterone‐Mediated Trade‐Offs
François Mougeot, Stephen M. Redpath, Stuart B. Piertney, Peter J. Hudson
The American Naturalist.2005; 166(2): 158. CrossRef
Enhanced survival of rats concurrently infected with Trypanosoma brucei and Strongyloides ratti
D.N Onah, I.W Onyenwe, J.I Ihedioha, O.S Onwumere
Veterinary Parasitology.2004; 119(2-3): 165. CrossRef
Interleukin (IL) 5 levels and eosinophilia in patients with intestinal parasitic diseases
Sebnem Ustun
World Journal of Gastroenterology.2004; 10(24): 3643. CrossRef
Effects of anti-allergic drugs on intestinal mastocytosis and worm expulsion of rats infected with Neodiplostomum seoulense
Eun-Hee Shin, Tae-Heung Kim, Sung-Jong Hong, Jae-Hwan Park, Sang-Mee Guk, Jong-Yil Chai
The Korean Journal of Parasitology.2003; 41(2): 81. CrossRef
Role of Intestinal Goblet Cells in the Expulsion of Gymnophalloides seoi From Mice
M. Seo, S-M. Guk, E-T. Han, J-Y. Chai
Journal of Parasitology.2003; 89(5): 1080. CrossRef
The relative involvement of Th1 and Th2 associated immune responses in the expulsion of a primary infection of Heligmosomoides polygyrus in mice of differing response phenotype
A. Ben-Smith, D.A. Lammas, J.M. Behnke
Journal of Helminthology.2003; 77(2): 133. CrossRef
Food-borne intestinal trematode infections in the Republic of Korea
Jong-Yil Chai, Soon-Hyung Lee
Parasitology International.2002; 51(2): 129. CrossRef
Intestinal histopathology and in situ postures of Gymnophalloides seoi in experimentally infected mice
Jong-Yil Chai, Hong-Soon Lee, Sung-Jong Hong, Jae Hyung Yoo, Sang-Mee Guk, Min Seo, Min-Ho Choi, Soon-Hyung Lee
The Korean Journal of Parasitology.2001; 39(1): 31. CrossRef
A review of Gymnophalloides seoi (Digenea: Gymnophallidae) and human infections in the Republic of Korea
Soon-Hyung Lee, Jong-Yil Chai
The Korean Journal of Parasitology.2001; 39(2): 85. CrossRef