Parasites, Hosts and Diseases

"sequencing"

Original Articles

Probiotic-induced changes in intestinal microbiome inhibits Toxoplasma gondii infection: Hak-Jae Lee, Do-Won Ham, Seung-Hwan Seo, Guang-Ho Cha, Eun-Hee Shin; Parasites Hosts Dis 2024;62(4):408-423.
Published online November 22, 2024; DOI: https://doi.org/10.3347/PHD.24068

Abstract
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Toxoplasma gondii primarily invades the central nervous system, causing latent infections. Cysts persist in the host for life and there is currently no effective treatment. T. gondii infects human hosts through contaminated meat, invading the intestinal tissue and leading to changes in the number and composition of the gut microbiota. Since probiotic ingestion modulates intestinal microbiota changes, we hypothesized that intestinal microbiota dysbiosis caused by T. gondii infection would be restored following probiotic supplementation. To this end, we orally infected C57BL/6 mice with 10 T. gondii cysts and administered supplemental probiotics daily. We analyzed the levels of T. gondii B1 gene DNA, indicative of T. gondii infection, in brain tissue. We investigated alterations in the gut microbiota composition and functional pathways between the probiotic and non-probiotic treatment groups via next-generation sequencing analysis of each fecal sample. The infection level in the probiotic-treated group was significantly reduced after 4 weeks (p<0.05). Probiotic supplementation notably changed the gut microbiota after 2 weeks of infection, increasing the relative abundance of Intestinimonas massiliensis and Lawsonibacter asaccharolyticus. Probiotic supplements appear to modulate the gut microbiota, activating functional pathways involved in intestinal short-chain fatty acid production and strengthening the intestinal barrier, thereby impeding T. gondii infection and subsequent proliferation. Our findings provide valuable insights into T. gondii infection control and future study directions.

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Lactobacillus vaginalis alleviates DSS induced colitis by regulating the gut microbiota and increasing the production of 3-indoleacrylic acid
Zhuoya Wang, Tian Liu, Li Liu, Jian Xie, Furui Tang, Yimin Pi, Yuchun Zhong, Zhidong He, Wenming Zhang, Cihua Zheng
Pharmacological Research.2025; 213: 107663. CrossRef
Gut microbiota-derived butyrate alleviates the impairment of mice intestinal integrity caused by Toxoplasma gondii infection
Shuni Liu, Yutao Zheng, Bingqian Cui, Jiayi Yang, Bohui Yuan, Yuhan Cao, Zimu Zhao, Zhuo Sun, Qingling Wang, Xiaoying Yang, Wei Pan, Cheng He
Life Sciences.2025; 374: 123709. CrossRef
Analysis of Gut Microbiota and Assessment of Environmental Health in Western Anatolian Vole (Microtus lydius Blackler, 1916)
Tuba Yağcı, Gözde Ayseçkin
Journal of Anatolian Environmental and Animal Sciences.2025; 10(4): 471. CrossRef
Microbiome of Dipteran vectors associated with integron and antibiotic resistance genes in South Korea
Xavier Chavarria, Arwa Shatta, Hyun Seo Park, Du-Yeol Choi, Dongjun Kang, Singeun Oh, Dawon Lee, Myungjun Kim, Jun Ho Choi, Yoon Hee Cho, Myung-hee Yi, Ju Yeong Kim
Acta Tropica.2025; 271: 107858. CrossRef
Urban environmental drivers of eukaryotic microbiota and parasite prevalence in domestic pigeon faeces: a metabarcoding-based public health risk assessment in Seoul, South Korea
Singeun Oh, Jun Ho Choi, Xavier Chavarria, Myungjun Kim, Dongjun Kang, Myung-hee Yi, Yoon Hee Cho, In-Yong Lee, Tai-Soon Yong, Seongjun Choe, Ju Yeong Kim
Journal of The Royal Society Interface.2025;[Epub] CrossRef

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The anti-amoebic activity of Pinus densiflora leaf extract against the brain-eating amoeba Naegleria fowleri: Hương Giang Lê, Woong Kim, Jung-Mi Kang, Tuấn Cường Võ, Won Gi Yoo, Hyeonsook Cheong, Byoung-Kuk Na; Parasites Hosts Dis 2024;62(2):169-179.
Published online May 27, 2024; DOI: https://doi.org/10.3347/PHD.23103

Naegleria fowleri invades the brain and causes a fatal primary amoebic meningoencephalitis (PAM). Despite its high mortality rate of approximately 97%, an effective therapeutic drug for PAM has not been developed. Approaches with miltefosine, amphotericin B, and other antimicrobials have been clinically attempted to treat PAM, but their therapeutic efficacy remains unclear. The development of an effective and safe therapeutic drug for PAM is urgently needed. In this study, we investigated the anti-amoebic activity of Pinus densiflora leaf extract (PLE) against N. fowleri. PLE induced significant morphological changes in N. fowleri trophozoites, resulting in the death of the amoeba. The IC50 of PLE on N. fowleri was 62.3±0.95 μg/ml. Alternatively, PLE did not significantly affect the viability of the rat glial cell line C6. Transcriptome analysis revealed differentially expressed genes (DEGs) between PLE-treated and non-treated amoebae. A total of 5,846 DEGs were identified, of which 2,189 were upregulated, and 3,657 were downregulated in the PLE-treated amoebae. The DEGs were categorized into biological process (1,742 genes), cellular component (1,237 genes), and molecular function (846 genes) based on the gene ontology analysis, indicating that PLE may have dramatically altered the biological and cellular functions of the amoeba and contributed to their death. These results suggest that PLE has anti-N. fowleri activity and may be considered as a potential candidate for the development of therapeutic drugs for PAM. It may also be used as a supplement compound to enhance the therapeutic efficacy of drugs currently used to treat PAM.

Citations

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A xanthone O-glucoside isolated from Iris setosa Pall. ex Link exhibits promising anti-amoebic activity against the brain-eating amoeba Naegleria fowleri
Hương Giang Lê, Buyng Su Hwang, Ji-Su Choi, Yong Tae Jeong, Tuấn Cường Võ, Minkyoung Cho, Yeonchul Hong, Jeong Ho Kim, Young Taek Oh, Byoung-Kuk Na
Phytomedicine.2025; 147: 157199. CrossRef
From nose to neurons: The lethal journey of the brain-eating amoeba Naegleria fowleri
Arindam Mitra, Débora Brito Goulart
The Microbe.2025; 8: 100537. CrossRef

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Brief Communications

Identification of Free-Living Amoebas in Tap Water of Buildings with Storage Tanks in Korea: Da-In Lee, Sung Hee Park, Jong Hwan Baek, Jee Won Yoon, Soo Im Jin, Kwang Eon Han, Hak Sun Yu; Korean J Parasitol 2020;58(2):191-194.
Published online April 30, 2020; DOI: https://doi.org/10.3347/kjp.2020.58.2.191

Abstract
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Free-living amoebas (FLAs) can cause severe disease in humans and animals when they become infected. However, there are no accurate survey reports on the prevalence of FLAs in Korea. In this study, we collected 163 tap water samples from buildings, apartments, and restrooms of highway service areas in 7 Korean provinces with high population density. All these buildings and facilities have water storage tanks in common. The survey was separated into categories of buildings, apartments, and highway service areas. Five hundred milliliters of tap water from each building was collected and filtered with 0.2 ?m pore filter paper. The filters were incubated in agar plates with heated E. coli at 25°C. After axenization, genomic DNA was collected from each FLA, and species classification was performed using partial 18S-rDNA PCR-sequencing analysis. We found that 12.9% of tap water from buildings with storage tanks in Korea was contaminated with FLAs. The highway service areas had the highest contamination rate at 33.3%. All of the FLAs, except one, were genetically similar to Vermamoeba vermiformis (Hartmannella vermiformis). The remaining FLA (KFA21) was very similar to Acanthamoeba lugdunensis (KA/E26). Although cases of human infection by V. vermiformis are very rare, we must pay attention to the fact that one-third of tap water supplies in highway service areas have been contaminated.

Citations

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A socioenvironmental approach to the nosogenic potential of freshwaters with presence of thermotolerant free-living amoebae in Costa Rica
Johan Alvarado-Ocampo, Juan José Romero Zúñiga, Julián Castro, Frida Chaves Monge, Marco Ruiz Campos, Alexa Bustamante Cortés, Elizabeth Abrahams Sandí, Lissette Retana Moreira
Frontiers in Public Health.2025;[Epub] CrossRef
Presence and diversity of free-living amoebae and their potential application as water quality indicators
Areum Choi, Ji Won Seong, Jeong Hyun Kim, Jun Young Lee, Hyun Jae Cho, Shin Ae Kang, Mi Kyung Park, Mi Jin Jeong, Seo Yeong Choi, Yu Jin Jeong, Hak Sun Yu
Parasites, Hosts and Diseases.2024; 62(2): 180. CrossRef
A Narrative Review of Acanthamoeba Isolates in Malaysia: Challenges in Infection Management and Natural Therapeutic Advancements
Mohammad Wisman Abdul Hamid, Roslaini Bin Abd Majid, Victor Fiezal Knight Victor Ernest, Nik Noorul Shakira Mohamed Shakrin, Firdaus Mohamad Hamzah, Mainul Haque
Cureus.2024;[Epub] CrossRef
Proper Management for Rigid Gas Permeable Contact and Orthokeratology Lens
Kyu Young Shim, Jong Hwa Jun
Annals of Optometry and Contact Lens.2023; 22(1): 7. CrossRef
Well water sources simultaneous contamination with Cryptosporidium and Acanthamoeba in East-Southeast Asia and Acanthamoeba spp. in biofilms in the Philippines
Frederick R. Masangkay, Giovanni D. Milanez, Joseph D. Dionisio, Luzelle Anne G.-L. Ormita, Abel V. Alvarez, Panagiotis Karanis
Science of The Total Environment.2022; 837: 155752. CrossRef
Recognition of Cell Wall Mannosylated Components as a Conserved Feature for Fungal Entrance, Adaptation and Survival Within Trophozoites of Acanthamoeba castellanii and Murine Macrophages
Marina da Silva Ferreira, Susana Ruiz Mendoza, Diego de Souza Gonçalves, Claudia Rodríguez-de la Noval, Leandro Honorato, Leonardo Nimrichter, Luís Felipe Costa Ramos, Fábio C. S. Nogueira, Gilberto B. Domont, José Mauro Peralta, Allan J. Guimarães
Frontiers in Cellular and Infection Microbiology.2022;[Epub] CrossRef
Free-living amoebae in an oil refinery wastewater treatment facility
Saeid Andalib, Hanieh Mohammad Rahimi, Maryam Niyyati, Farzaneh Shalileh, Sara Nemati, Soheila Rouhani, Mohammad Reza Zali, Hamed Mirjalali, Panagiotis Karanis
Science of The Total Environment.2022; 839: 156301. CrossRef
Free-Living Amoeba Vermamoeba vermiformis Induces Allergic Airway Inflammation
Da-In Lee, Sung Hee Park, Shin-Ae Kang, Do Hyun Kim, Sun Hyun Kim, So Yeon Song, Sang Eun Lee, Hak Sun Yu
The Korean Journal of Parasitology.2022; 60(4): 229. CrossRef
The increasing importance of Vermamoebavermiformis
Ruqaiyyah Siddiqui, Zinb Makhlouf, Naveed Ahmed Khan
Journal of Eukaryotic Microbiology.2021;[Epub] CrossRef

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Monitoring of Pyrethroid Resistance Allele Frequency in the Common Bed Bug (Cimex lectularius) in the Republic of Korea: Susie Cho, Heung-Chul Kim, Sung-Tae Chong, Terry A. Klein, Deok Ho Kwon, Si Hyeock Lee, Ju Hyeon Kim; Korean J Parasitol 2020;58(1):99-102.
Published online February 29, 2020; DOI: https://doi.org/10.3347/kjp.2020.58.1.99

Abstract
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Two-point mutations (V419L and L925I) on the voltage-sensitive sodium channel of bed bugs (Cimex lectularius) are known to confer pyrethroid resistance. To determine the status of pyrethroid resistance in bed bugs in Korea, resistance allele frequencies of bed bug strains collected from several US military installations in Korea and Mokpo, Jeollanamdo, from 2009-2019 were monitored using a quantitative sequencing. Most bed bugs were determined to have both of the point mutations except a few specimens, collected in 2009, 2012 and 2014, having only a single point mutation (L925I). No susceptible allele was observed in any of the bed bugs examined, suggesting that pyrethroid resistance in bed bug populations in Korea has reached a serious level. Large scale monitoring is required to increase our knowledge on the distribution and prevalence of pyrethroid resistance in bed bug populations in Korea. Based on present study, it is urgent to restrict the use of pyrethroids and to introduce effective alternative insecticides. A nation-wide monitoring program to determine the pyrethroid resistance level in bed bugs and to select alternative insecticides should be implemented.

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Toxicodynamic and toxicokinetic mechanisms underlying deltamethrin resistance and dinotefuran cross-resistance in two resistant strains of common bed bug, Cimex lectularius
Susie Cho, Hyun Kyu Shin, Heung Chul Kim, J. Marshall Clark, Si Hyeock Lee, Ju Hyeon Kim
Pesticide Biochemistry and Physiology.2026; 217: 106874. CrossRef
Widespread fixation of kdr-associated mutations in temporal samples of Cimex lectularius collected from multi-unit buildings
Jin-Jia Yu, Warren Booth, Changlu Wang
Journal of Pest Science.2026;[Epub] CrossRef
Multiple mechanisms associated with deltamethrin and imidacloprid resistance in field-collected common bed bug, Cimex lectularius L.
Jin-Jia Yu, Shao-Hung Lee, Chow-Yang Lee, Changlu Wang
Pesticide Biochemistry and Physiology.2025; 210: 106357. CrossRef
Global Perspective of Insecticide Resistance in Bed Bugs and Management Options
Chow‐Yang Lee
Entomological Research.2025;[Epub] CrossRef
Population genetics as a tool to understand invasion dynamics and insecticide resistance in indoor urban pest insects
Warren Booth
Current Opinion in Insect Science.2024; 62: 101166. CrossRef
Species identification and pyrethroid resistance genotyping of recently resurgent Cimex lectularius and Cimex hemipterus in Korea
Susie Cho, Heung Chul Kim, Hoonsik Eom, Jae Rok Lee, Chung Hyun Ko, E-hyun Shin, Won Kyu Lee, Si Hyeock Lee, Ju Hyeon Kim
Parasites, Hosts and Diseases.2024; 62(2): 251. CrossRef
2023–2024년 국내에서 발생한 빈대의 분포 조사
기훈 김, 선란 조, 희일 이
Public Health Weekly Report.2024; 17(45): 1956. CrossRef
Decade long upsurge in mutations associated with pyrethroid resistance in bed bug populations in the USA
Cari D. Lewis, Brenna A. Levine, Coby Schal, Edward L. Vargo, Warren Booth
Journal of Pest Science.2023; 96(1): 415. CrossRef
The Efficacy of a Pyrethroid-impregnated Mattress Liner on Multiple International Strains ofCimex lectularius(Hemiptera: Cimicidae) andCimex hemipterus(Hemiptera: Cimicidae)
Xin-Yeng Leong, Chow-Yang Lee, G Veera Singham, Alexander Chong Shu-Chien, Richard Naylor, Alexia Naylor, Dini M Miller, Morgan M Wilson, David G Lilly, Stephen L Doggett, Changlu Wang
Journal of Economic Entomology.2023; 116(1): 19. CrossRef
Insecticide Resistance of Cimex lectularius L. Populations and the Performance of Selected Neonicotinoid-Pyrethroid Mixture Sprays and an Inorganic Dust
Jin-Jia Yu, Sabita Ranabhat, Changlu Wang
Insects.2023; 14(2): 133. CrossRef
The first recent case ofCimex hemipterus(Hemiptera: Cimicidae) withsuper-kdrmutations in the Republic of Korea
Susie Cho, E-hyun Shin, Ho Cheol Ju, Eui Seok Jeong, Si Hyeock Lee, Ju Hyeon Kim, Warren Booth
Journal of Medical Entomology.2023; 60(4): 822. CrossRef

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Case Report

The First Acanthamoeba keratitis Case of Non-Contact Lens Wearer with HIV Infection in Thailand: Napaporn Tananuvat, Natnaree Techajongjintana, Pradya Somboon, Anchalee Wannasan; Korean J Parasitol 2019;57(5):505-511.
Published online October 31, 2019; DOI: https://doi.org/10.3347/kjp.2019.57.5.505

Abstract
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Acanthamoeba keratitis (AK) is a rare sight-threatening corneal infection, often reporting from contact lens wearers. An asymptomatic human immunodeficiency virus (HIV)-infected Thai male without history of contact lens use complained foreign body sensation at his left eye during motorbike riding. He had neither specific keratitis symptoms nor common drugs responding, which contributed to delayed diagnosis. By corneal re-scraping, Acanthamoeba-like cysts were detected by calcofluor white staining and agar culture. The etiological agent obtained from the culture was molecularly confirmed by Acanthamoeba spp.-specific PCR, followed by DNA sequencing. The results from BLAST and phylogenetic analysis based on the DNA sequences, revealed that the pathogen was Acanthamoeba T4, the major genotype most frequently reported from clinical isolates. The infection was successfully treated with polyhexamethylene biguanide resulting in corneal scar. This appears the first reported AK case from a non-contact lens wearer with HIV infection in Thailand. Although AK is sporadic in developing countries, a role of free-living Acanthamoeba as an opportunistic pathogen should not be neglected. The report would increase awareness of AK, especially in the case presenting unspecific keratitis symptoms without clinical response to empirical antimicrobial therapy.

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Detection of Free-Living Amoeba in a tertiary care hospital
Nairita Choudhuri, Bhaskar Narayan Chaudhuri, Partha Guchhait, Arup Kumar Dawn, Satadal Das
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Matthew Azzopardi, Yu Jeat Chong, Benjamin Ng, Alberto Recchioni, Abison Logeswaran, Darren S. J. Ting
Diagnostics.2023; 13(16): 2655. CrossRef
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Biology.2023; 12(12): 1489. CrossRef
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Ehsan Javanmard, Maryam Niyyati, Ali Taghipour, Marziye Fatemi, Hamed Mirjalali, Panagiotis Karanis
Journal of Water and Health.2022; 20(4): 620. CrossRef
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Hadi Khatoonaki, Kavous Solhjoo, Hassan Rezanezhad, Belal Armand, Amir Abdoli, Ali Taghipour
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Detection of Acanthamoeba from Acanthamoeba Keratitis Mouse Model Using Acanthamoeba-Specific Antibodies
Min-Jeong Kim, A-Jeong Ham, A-Young Park, Hae-Jin Sohn, Ho-Joon Shin, Fu-Shi Quan, Hyun-Hee Kong, Eun-Kyung Moon
Microorganisms.2022; 10(9): 1711. CrossRef
RETRACTED ARTICLE: Establishment of an Acanthamoeba keratitis mouse model confirmed by amoebic DNA amplification
Heekyoung Kang, Hae-Jin Sohn, A-Young Park, A-Jeong Ham, Jeong-Heon Lee, Young-Hwan Oh, Yong-Joon Chwae, Kyongmin Kim, Sun Park, Hongseok Yang, Suk-Yul Jung, Jong-Hyun Kim, Ho-Joon Shin
Scientific Reports.2021;[Epub] CrossRef
Genotype distribution of Acanthamoeba in keratitis: a systematic review
Maria Luisa Nunes Diehl, Júlia Paes, Marilise Brittes Rott
Parasitology Research.2021; 120(9): 3051. CrossRef
Explicating the presentations of Acanthamoeba keratitis with special concern in the COVID-19 pandemic ambient
Chukwuma Sr Chrysanthus
International Journal of Clinical Microbiology and Biochemical Technology.2021; 4(1): 010. CrossRef
Effectiveness and Safety of Topical Chlorhexidine and Vitamin E TPGS in the Treatment of Acanthamoeba Keratitis: A Survey on 29 Cases
Ciro Caruso, Daniela Eletto, Michele Rinaldi, Luigi Pacente, Salvatore Troisi, Francesco Semeraro, Roberto dell’Omo, Ciro Costagliola
Journal of Clinical Medicine.2020; 9(11): 3775. CrossRef

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Brief Communications

Molecular Identification of Anisakis Larvae Extracted by Gastrointestinal Endoscopy from Health Check-up Patients in Korea: Hyemi Song, Bong-Kwang Jung, Jaeeun Cho, Taehee Chang, Sun Huh, Jong-Yil Chai; Korean J Parasitol 2019;57(2):207-211.
Published online April 30, 2019; DOI: https://doi.org/10.3347/kjp.2019.57.2.207

Anisakiasis is a zoonotic disease induced by anisakid nematodes, and endoscopic inspection is used for a diagnosis or remedy for it. Anisakis simplex, Anisakis physeteris, and Pseudoterranova decipiens had been reported to be the major species causing human infections, particularly, in Japan. However, in Korea, recent studies strongly suggested that Anisakis pegreffii is the major species of human infections. To support this suggestion, we collected anisakid larvae (n=20) from 20 human patients who were undergone gastrointestinal endoscopy at a health check-up center in Korea, and molecular identification was performed on the larvae using PCR-RFLP analysis and gene sequencing of rDNA ITS regions and mtDNA cox2. In addition, anisakid larvae (n=53) collected from the sea eel (Astroconger myriaster) were also examined for comparison with those extracted from humans. The results showed that all human samples (100%) were identified as A. pegreffii, whereas 90.7% of the samples from the sea eel were A. pegreffii with the remaining 9.3% being Hysterothylacium aduncum. Our study confirmed that A. pegreffii is the predominant species causing human anisakiasis in Korea, and this seems to be due to the predominance of this larval type in the fish (sea eels) popularly consumed by the Korean people. The possibility of human infection with H. aduncum in Korea is also suggested.

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Parasites, Hosts and Diseases.2024; 62(3): 351. CrossRef
Genetic analyses of Anisakis pegreffii (Nematoda: Anisakidae) from the East Asian finless porpoise Neophocaena asiaeorientalis sunameri (Cetacea: Phocoenidae) in Korean waters
Sunmin Kim, Jong Yoon Jeon, Kyunglee Lee, Hyunjoo Lee, Han Chan Park, Kyung Eun Lee, Hang Lee, Sung Bin Lee, Sang Wha Kim, Se Chang Park, Seongjun Choe, Heejeong Youn
Parasitology Research.2024;[Epub] CrossRef
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Sunmin Kim, Bom Sok Lee, Seongjun Choe
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E. Mercken, I. Van Damme, A. Serradell, S. Gabriël
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International Journal of Food Microbiology.2020; 327: 108657. CrossRef
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Fasciola hepatica: Infection Status of Freshwater Snails Collected from Gangwon-do (Province), Korea: Jae-Hyung Lee, Juan-Hua Quan, In-Wook Choi, Gab-Man Park, Guang-Ho Cha, Hyun-Ju Kim, Jae-Min Yuk, Young-Ha Lee; Korean J Parasitol 2017;55(1):95-98.
Published online February 28, 2017; DOI: https://doi.org/10.3347/kjp.2017.55.1.95

Abstract
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Fasciola hepatica is a trematode that causes zoonosis, mainly in cattle and sheep, and occasionally in humans. Few recent studies have determined the infection status of this fluke in Korea. In August 2015, we collected 402 samples of freshwater snails at Hoenggye-ri (upper stream) and Suha-ri (lower stream) of Song-cheon (stream) in Daegwalnyeong-myeon, Pyeongchang-gun in Gangwon-do (Province) near many large cattle or sheep farms. F. hepatica infection was determined using PCR on the nuclear ribosomal internal transcribed spacer 2 (ITS-2). Among the 402 samples, F. hepatica 1TS-2 marker was detected in 6 freshwater snails; thus, the overall prevalence in freshwater snails was 1.5%. The prevalence varied between collection areas, ranging from 0.0% at Hoenggye-ri to 2.9% at Suha-ri. However, F. gigantica ITS-2 was not detected in the 6 F. hepatica-positive samples by PCR. The nucleotide sequences of the 6 F. hepatica ITS-2 PCR-positive samples were 99.4% identical to the F. hepatica ITS-2 sequences in GenBank, whereas they were 98.4% similar to F. gigantica ITS-2 sequences. These results indicated that the prevalence of F. hepatica in snail intermediate hosts was 1.5% in Gangwon-do, Korea; however the prevalence varied between collection areas. These results may help us to understand F. hepatica infection status in natural environments.

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Fasciola hepatica infection in Korean water deer (Hydropotes inermis argyropus)
Na-Hyeon Kim, Min-Gyeong Seo, Bumseok Kim, Yu Jeong Jeon, In Jung Jung, Il-Hwa Hong
Parasites, Hosts and Diseases.2025; 63(3): 243. CrossRef
Countering Zoonotic Diseases: Current Scenario and Advances in Diagnostics, Monitoring, Prophylaxis and Therapeutic Strategies
Saurabh Gupta, Rasanpreet Kaur, Jagdip Singh Sohal, Shoor Vir Singh, Kaushik Das, Manish Kumar Sharma, Jitendra Singh, Shalini Sharma, Kuldeep Dhama
Archives of Medical Research.2024; 55(6): 103037. CrossRef
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Akash Gupta, Prabhat Khanal
Journal of Agriculture and Food Research.2024; 18: 101330. CrossRef
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MC Mathole, PH King
African Journal of Aquatic Science.2023; 48(1): 71. CrossRef
Epidemiology of Fasciola spp. in the intermediate host in China: A potential risk for fasciolosis transmission
Ming Pan, Shao-Yuan Bai, Tian-Kai Ji, Yi-Min Fan, Dan-Dan Liu, Yi Yang, Jian-Ping Tao, Si-Yang Huang
Acta Tropica.2022; 230: 106394. CrossRef
Economic losses, morpho-molecular identification, and identity of Fasciola species recovered from Egypt
Omima Ramadan Abdel‑Fatah, Waleed M. Arafa, Ahmed Anwar Wahba, Khaled Mohamed El‑Dakhly
Journal of Parasitic Diseases.2022; 46(4): 1036. CrossRef
Green vegetable juice as a potential source of human fascioliasis in Korea
Sungim Choi, Sunghee Park, Sooji Hong, Hyejoo Shin, Bong-Kwang Jung, Min Jae Kim
One Health.2022; 15: 100441. CrossRef
Human and Animal Fascioliasis: Origins and Worldwide Evolving Scenario
Santiago Mas-Coma, M. Adela Valero, M. Dolores Bargues
Clinical Microbiology Reviews.2022;[Epub] CrossRef
Living Liver Donor With Fasciola Hepatica: First Case Report in the Literature
Sami Akbulut, Tevfik Tolga Sahin, Mehmet Kolu, Burak Isik, Yasar Bayindir, Sezai Yilmaz
Experimental and Clinical Transplantation.2021; 19(3): 276. CrossRef
Trematode cercarial fauna obtained from the field-collected freshwater snails Lymnaea natalensis in Egypt
Amina M. Ibrahim, Amira Kamal Ahmed
Bulletin of the National Research Centre.2019;[Epub] CrossRef
Assessment of the molluscicidal impact of extracted chlorophyllin on some biochemical parameters in the nervous tissue and histological changes in Biomphalaria alexandrina and Lymnaea natalensis snails
Amina M. Ibrahim, Fayez A. Bakry
Invertebrate Neuroscience.2019;[Epub] CrossRef
A Case of Fascioliasis in A Wild Nutria, Myocastor coypus, in Republic of Korea
Hyo-Seok Kim, Joo-Yeon Kong, Jong-Hyun Kim, Seong-Chan Yeon, Il-Hwa Hong
The Korean Journal of Parasitology.2018; 56(4): 375. CrossRef
Purification and biochemical characterization of a 22-kDa stable cysteine- like protease from the excretory-secretory product of the liver fluke Fasciola hepatica by using conventional techniques
Ahmed Hemici, Roumaila Sabrina Benerbaiha, Dalila Bendjeddou
Journal of Chromatography B.2017; 1068-1069: 268. CrossRef

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Original Article

Draft Genome of Toxocara canis, a Pathogen Responsible for Visceral Larva Migrans: Jinhwa Kong, Jungim Won, Jeehee Yoon, UnJoo Lee, Jong-Il Kim, Sun Huh; Korean J Parasitol 2016;54(6):751-758.
Published online December 31, 2016; DOI: https://doi.org/10.3347/kjp.2016.54.6.751

Abstract
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This study aimed at constructing a draft genome of the adult female worm Toxocara canis using next-generation sequencing (NGS) and de novo assembly, as well as to find new genes after annotation using functional genomics tools. Using an NGS machine, we produced DNA read data of T. canis. The de novo assembly of the read data was performed using SOAPdenovo. RNA read data were assembled using Trinity. Structural annotation, homology search, functional annotation, classification of protein domains, and KEGG pathway analysis were carried out. Besides them, recently developed tools such as MAKER, PASA, Evidence Modeler, and Blast2GO were used. The scaffold DNA was obtained, the N50 was 108,950 bp, and the overall length was 341,776,187 bp. The N50 of the transcriptome was 940 bp, and its length was 53,046,952 bp. The GC content of the entire genome was 39.3%. The total number of genes was 20,178, and the total number of protein sequences was 22,358. Of the 22,358 protein sequences, 4,992 were newly observed in T. canis. Following proteins previously unknown were found: E3 ubiquitin-protein ligase cbl-b and antigen T-cell receptor, zeta chain for T-cell and B-cell regulation; endoprotease bli-4 for cuticle metabolism; mucin 12Ea and polymorphic mucin variant C6/1/40r2.1 for mucin production; tropomodulin-family protein and ryanodine receptor calcium release channels for muscle movement. We were able to find new hypothetical polypeptides sequences unique to T. canis, and the findings of this study are capable of serving as a basis for extending our biological understanding of T. canis.

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Parasites in Sewage: Legal Requirements and Diagnostic Tools
Oliwia Obuch-Woszczatyńska, Klaudia Bylińska, Małgorzata Krzyżowska, Karol Korzekwa, Piotr Bąska
Pathogens.2025; 14(1): 86. CrossRef
Toward anthelmintic drug candidates for toxocariasis: Challenges and recent developments
Ana C. Mengarda, Tais C. Silva, Aline S. Silva, Daniel B. Roquini, João Paulo S. Fernandes, Josué de Moraes
European Journal of Medicinal Chemistry.2023; 251: 115268. CrossRef
Antigenic Proteins from the Excretory–Secretory Products of Toxocara canis Larvae and Evaluation of Their Potential for Immunodiagnostics of Larval Toxocarosis
Kateřina Skulinová, Jan Novák, Libuše Kolářová, Martin Kašný
Acta Parasitologica.2022; 67(2): 705. CrossRef
GAAP: A Genome Assembly + Annotation Pipeline
Jinhwa Kong, Sun Huh, Jung-Im Won, Jeehee Yoon, Baeksop Kim, Kiyong Kim
BioMed Research International.2019; 2019: 1. CrossRef

15,218 View
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Brief Communications

Molecular Description of Macroorchis spinulosus (Digenea: Nanophyetidae) Based on ITS1 Sequences: Eun Jeong Won, Deok-Gyu Kim, Jaeeun Cho, Bong-Kwang Jung, Min-Jae Kim, Yong Woon Yun, Jong-Yil Chai, Dong Wook Ryang; Korean J Parasitol 2016;54(1):109-112.
Published online February 26, 2016; DOI: https://doi.org/10.3347/kjp.2016.54.1.109

Abstract
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We performed a molecular genetic study on the sequences of 18S ribosomal RNA (ITS1 region) gene in 4-day-old adult worms of Macroorchis spinulosus recovered in mice experimentally infected with metacercariae from crayfish in Jeollanam-do Province, Korea. The metacercariae were round, 180 μm in average diameter, encysted with 2 layers of thick walls, but the stylet on the oral sucker was not clearly seen. The adult flukes were oval shape, and 760-820 μm long and 320-450 μm wide, with anterolateral location of 2 large testes. The phylogenetic tree based on ITS1 sequences of 6 M. spinulosus samples showed their distinguished position from other trematode species in GenBank. The most closely resembled group was Paragonimus spp. which also take crayfish or crabs as the second intermediate host. The present study is the first molecular characterization of M. spinulosus and provided a basis for further phylogenetic studies to compare with other trematode fauna in Korea.

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Origins, phylogenetic relationships and host-parasite interactions of Troglotrematoidea since the cretaceous
Konstantin S. Vainutis, Anastasia N. Voronova, Georg G. Duscher, Egor M. Shchelkanov, Mikhail Yu. Shchelkanov
Infection, Genetics and Evolution.2022; 101: 105274. CrossRef
Morphological and Molecular Characteristics of Clinostomid Metacercariae from Korea and Myanmar
Eun Jeong Won, Yu Jeong Lee, Moon-Ju Kim, Jong-Yil Chai, Byoung-Kuk Na, Woon-Mok Sohn
The Korean Journal of Parasitology.2020; 58(6): 635. CrossRef
Metagonimus suifunensis sp. n. (Trematoda: Heterophyidae) from the Russian Southern Far East: Morphology, life cycle, and molecular data
P.G. Shumenko, Y.V. Tatonova, V.V. Besprozvannykh
Parasitology International.2017; 66(1): 982. CrossRef

8,748 View
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Monitoring of Fasciola Species Contamination in Water Dropwort by COX1 Mitochondrial and ITS-2 rDNA Sequencing Analysis: In-Wook Choi, Hwang-Yong Kim, Juan-Hua Quan, Jae-Gee Ryu, Rubing Sun, Young-Ha Lee; Korean J Parasitol 2015;53(5):641-645.
Published online October 29, 2015; DOI: https://doi.org/10.3347/kjp.2015.53.5.641

Abstract
PDF

Fascioliasis, a food-borne trematode zoonosis, is a disease primarily in cattle and sheep and occasionally in humans. Water dropwort (Oenanthe javanica), an aquatic perennial herb, is a common second intermediate host of Fasciola, and the fresh stems and leaves are widely used as a seasoning in the Korean diet. However, no information regarding Fasciola species contamination in water dropwort is available. Here, we collected 500 samples of water dropwort in 3 areas in Korea during February and March 2015, and the water dropwort contamination of Fasciola species was monitored by DNA sequencing analysis of the Fasciola hepatica and Fasciola gigantica specific mitochondrial cytochrome c oxidase subunit 1 (cox1) and nuclear ribosomal internal transcribed spacer 2 (ITS-2). Among the 500 samples assessed, the presence of F. hepatica cox1 and 1TS-2 markers were detected in 2 samples, and F. hepatica contamination was confirmed by sequencing analysis. The nucleotide sequences of cox1 PCR products from the 2 F. hepatica-contaminated samples were 96.5% identical to the F. hepatica cox1 sequences in GenBank, whereas F. gigantica cox1 sequences were 46.8% similar with the sequence detected from the cox1 positive samples. However, F. gigantica cox1 and ITS-2 markers were not detected by PCR in the 500 samples of water dropwort. Collectively, in this survey of the water dropwort contamination with Fasciola species, very low prevalence of F. hepatica contamination was detected in the samples.

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Isolation and molecular identification of liver fluke cercariae in freshwater snails of Chaharmahal and Bakhtiari province, Iran
Bijan Hosseinpour Aghaei, Nadia Taiefi Nasrabadi, Yaser Pirali Kheirabadi, Seyed Shapoor Reza Shojaei
Molluscan Research.2024; 44(1): 84. CrossRef
Morphological and molecular identification of lymnaeid snail and trematodes cercariae in different water bodies in Perak, Malaysia
Nazir Ahmad Tookhy, Nur Mahiza Md Isa, Rozaihan Mansor, Yasmin Abd Rahaman, Nur Indah Ahmad, Dung Thi Bui, Lokman Hakim Idris, Noor Hazfalinda Hamzah, Norhadila Zulkifli
Parasitology Research.2023; 122(7): 1475. CrossRef
Green vegetable juice as a potential source of human fascioliasis in Korea
Sungim Choi, Sunghee Park, Sooji Hong, Hyejoo Shin, Bong-Kwang Jung, Min Jae Kim
One Health.2022; 15: 100441. CrossRef
Phylogenetic Characteristics of Fasciola hepatica Isolated from a Korean Patient
Mi Jin Jeong, Jae Kyun Park, Hak Sun Yu
The Korean Journal of Parasitology.2022; 60(5): 367. CrossRef
A Descriptive Study of Human Fascioliasis in Qaemshahr, Mazandaran Province, Iran: Its Prevalence and Risk Factors
Lotfollah Davoodi, Azadeh Mizani, Roya Najafi-Vosough, Saeed Hosseini Teshnizi, afsane amouei, Mousa Motavallihaghi, Hamideh Izadyar, Fateme Amuei, Sara Pourhaghighi, Seyed Reza Mirbadie, Eissa Soleymani
Archives of Clinical Infectious Diseases.2022;[Epub] CrossRef
A Review ofOenanthe javanica(Blume) DC. as Traditional Medicinal Plant and Its Therapeutic Potential
Chuan-li Lu, Xiu-fen Li
Evidence-Based Complementary and Alternative Medicine.2019; 2019: 1. CrossRef
Human fascioliasis infection sources, their diversity, incidence factors, analytical methods and prevention measures
S. Mas-Coma, M. D. Bargues, M. A. Valero
Parasitology.2018; 145(13): 1665. CrossRef

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Case Reports

Three Cases of Diphyllobothrium nihonkaiense Infection in Korea: Hong-Ja Kim, Keeseon S. Eom, Min Seo; Korean J Parasitol 2014;52(6):673-676.
Published online December 23, 2014; DOI: https://doi.org/10.3347/kjp.2014.52.6.673

Abstract
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Until 2012, a total of 48 cases of diphyllobothriasis had been reported in Korea, all of which were morphologically identified as Diphyllobothrium latum. However, some of these specimens were analyzed by nucleotide sequencing of the mitochondrial cox1 gene, which showed that all were D. nihonkaiense, not D. latum. After that, 3 further cases of diphyllobothriasis were confirmed as D. nihonkaiense. In the present study, 3 new cases of D. nihonkaiense were detected from 2011 through 2013. The hosts were infected through consumption of salmonid fishes, such as the trout or salmon, and 2 of them experienced severe diarrhea prior to proglottid passage. All of the tapeworms were confirmed to be D. nihonkaiense by genetic identification. This proved again that most diphyllobothriasis in Korea have been caused by D. nihonkaiense.

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Locally acquired infection with Dibothriocephalus nihonkaiense (=Diphyllobothrium nihonkaiense) in France: the importance of molecular diagnosis
Valentin Greigert, Julie Brunet, Alexander W. Pfaff, Jean-Philippe Lemoine, Ermanno Candolfi, Ahmed Abou-Bacar
Parasitology Research.2020; 119(2): 513. CrossRef
Epidemiology ofDiphyllobothrium nihonkaienseDiphyllobothriasis, Japan, 2001–2016
Hiroshi Ikuno, Shinkichi Akao, Hiroshi Yamasaki
Emerging Infectious Diseases.2018;[Epub] CrossRef
Molecular Identification of Diphyllobothrium latum from a Pediatric Case in Taiwan
Yu-Chin An, Chia-Cheng Sung, Chih-Chien Wang, Hsin-Chung Lin, Kuang-Yao Chen, Fu-Man Ku, Ruei-Min Chen, Mei-Li Chen, Kuo-Yang Huang
The Korean Journal of Parasitology.2017; 55(4): 425. CrossRef
Eggs as a Suitable Tool for Species Diagnosis of Causative Agents of Human Diphyllobothriosis (Cestoda)
Kateřina Leštinová, Miroslava Soldánová, Tomáš Scholz, Roman Kuchta, Ricardo Toshio Fujiwara
PLOS Neglected Tropical Diseases.2016; 10(5): e0004721. CrossRef
Diphyllobothrium nihonkaiense: wide egg size variation in 32 molecularly confirmed adult specimens from Korea
Seoyun Choi, Jaeeun Cho, Bong-Kwang Jung, Deok-Gyu Kim, Sarah Jiyoun Jeon, Hyeong-Kyu Jeon, Keeseon S. Eom, Jong-Yil Chai
Parasitology Research.2015; 114(6): 2129. CrossRef
Molecular Identification of <i>Diphyllobothrium nihonkaiense</i> from 3 Human Cases in Heilongjiang Province with a Brief Literature Review in China
Weizhe Zhang, Fei Che, Song Tian, Jing Shu, Xiaoli Zhang
The Korean Journal of Parasitology.2015; 53(6): 683. CrossRef

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Eosinophilic Pleuritis due to Sparganum: A Case Report: Youngmin Oh, Jeong-Tae Kim, Mi-Kyeong Kim, You-Jin Chang, Keeseon Eom, Jung-Gi Park, Ki-Man Lee, Kang-Hyeon Choe, Jin-Young An; Korean J Parasitol 2014;52(5):541-543.
Published online October 22, 2014; DOI: https://doi.org/10.3347/kjp.2014.52.5.541

Abstract
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Sparganosis is a rare parasitic disease caused by migrating plerocercoid tapeworm larva of the genus Spirometra. Infection in humans is mainly caused by the ingestion of raw or inadequately cooked flesh of infected frogs, snakes, and chickens. Here, we report a rare case of a 45-year-old man who was admitted to our hospital with left lower chest pain. The chest radiograph and computed tomography (CT) scan revealed localized pleural effusion in the left lower lobe; further, peripheral blood eosinophilia and eosinophilic pleural effusion were present. Percutaneous catheter drainage was performed, which revealed long worm-shaped material that was identified as a sparganum by DNA sequencing. The patient showed clinical improvement after drainage of the sparganum. This study demonstrates the importance of considering parasitic diseases in the differential diagnosis of eosinophilic pleural effusion.

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Pleural effusion caused by Trichinella spiralis infection: two case reports
Zhen-zhen Pan, Miao-juan Zhu, Yu-qiong Rong, Jiong Yang
BMC Infectious Diseases.2023;[Epub] CrossRef
Epidemiology, Diagnosis, and Prevention of Sparganosis in Asia
Wei Liu, Tengfang Gong, Shuyu Chen, Quan Liu, Haoying Zhou, Junlin He, Yong Wu, Fen Li, Yisong Liu
Animals.2022; 12(12): 1578. CrossRef
Incidence, aetiology and clinical features of eosinophilic pleural effusion: a retrospective study
Minfang Li, Yunxiang Zeng, Yaqing Li, Dan Jia, Sheng Chen, Jinlin Wang
BMC Pulmonary Medicine.2021;[Epub] CrossRef
Recurrent eosinophilic pleuritis caused by sparganum infection
Liangjie Fang, Yuehong Wang, Qiqi Gao, Bing Yan, Jianying Zhou
Medicine.2020; 99(22): e20226. CrossRef
Retrospective study of pleural parasitic infestations: a practical diagnostic approach
Jinlin Wang, Weizhan Luo, Panxiao Shen, Jianxing He, Yunxiang Zeng
BMC Infectious Diseases.2019;[Epub] CrossRef
Eosinophilia in Pleural Effusions: a Speculative Negative Predictor for Malignancy
Fang-Yeh Chu, Ching-Biau Liou, Jen-Tang Sun, Chia-Hao Bei, Tse-Hsuan Liou, N-Chi Tan, Yun-Chieh Yu, Chih-Chun Chang, Tzung-Hai Yen, Ming-Jang Su
Asian Pacific Journal of Cancer Prevention.2016; 17(3): 1411. CrossRef
Clinical Features of Pulmonary Sparganosis
Ning Li, Yi Xiang, Yun Feng, Min Li, Bei Li Gao, Qing Yun Li
The American Journal of the Medical Sciences.2015; 350(6): 436. CrossRef

9,649 View
83 Download
6 Web of Science
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Brief Communication

Whole Mitochondrial Genome Sequence of an Indian Plasmodium falciparum Field Isolate: Suchi Tyagi, Veena Pande, Aparup Das; Korean J Parasitol 2014;52(1):99-103.
Published online February 19, 2014; DOI: https://doi.org/10.3347/kjp.2014.52.1.99

Abstract
PDF

Mitochondrial genome sequence of malaria parasites has served as a potential marker for inferring evolutionary history of the Plasmodium genus. In Plasmodium falciparum, the mitochondrial genome sequences from around the globe have provided important evolutionary understanding, but no Indian sequence has yet been utilized. We have sequenced the whole mitochondrial genome of a single P. falciparum field isolate from India using novel primers and compared with the 3D7 reference sequence and 1 previously reported Indian sequence. While the 2 Indian sequences were highly divergent from each other, the presently sequenced isolate was highly similar to the reference 3D7 strain.

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Long-read DNA sequencing reveals the organization of the mitochondrial genome in the early-branching dinoflagellate Oxyrrhis marina.
Ronie Haro, Nikita Walunjkar, Soham Jorapur, Claudio H. Slamovits
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Mitochondrial population genomic analyses reveal population structure and demography of Indian Plasmodium falciparum
Suchi Tyagi, Aparup Das
Mitochondrion.2015; 24: 9. CrossRef
New insights into the evolutionary history of Plasmodium falciparum from mitochondrial genome sequence analyses of Indian isolates
Suchi Tyagi, Veena Pande, Aparup Das
Molecular Ecology.2014; 23(12): 2975. CrossRef
Mitochondrial genome sequence diversity of Indian Plasmodium falciparum isolates
Suchi Tyagi, Veena Pande, Aparup Das
Memórias do Instituto Oswaldo Cruz.2014; 109(4): 494. CrossRef

13,238 View
112 Download
8 Web of Science
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Case Report

A Case of Plasmodium ovale Malaria Imported from West Africa: Yunjung Kang, Jinyoung Yang; Korean J Parasitol 2013;51(2):213-218.
Published online April 25, 2013; DOI: https://doi.org/10.3347/kjp.2013.51.2.213

Abstract
PDF

Malaria is a parasitic infection caused by Plasmodium species. Most of the imported malaria in Korea are due to Plasmodium vivax and Plasmodium falciparum, and Plasmodium ovale infections are very rare. Here, we report a case of a 24-year-old American woman who acquired P. ovale while staying in Ghana, West Africa for 5 months in 2010. The patient was diagnosed with P. ovale malaria based on a Wright-Giemsa stained peripheral blood smear, Plasmodium genus-specific real-time PCR, Plasmodium species-specific nested PCR, and sequencing targeting 18S rRNA gene. The strain identified had a very long incubation period of 19-24 months. Blood donors who have malaria with a very long incubation period could be a potential danger for propagating malaria. Therefore, we should identify imported P. ovale infections not only by morphological findings but also by molecular methods for preventing propagation and appropriate treatment.

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Malaria Journal.2025;[Epub] CrossRef
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Hyun-Il Shin, Bora Ku, Yu Jung Kim, Tae Yun Kim, Shin-Hyeong Cho, Sang-Eun Lee
The Korean Journal of Parasitology.2020; 58(1): 61. CrossRef
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Joachim Richter, Gabriele Franken, Martha C. Holtfreter, Susanne Walter, Alfons Labisch, Heinz Mehlhorn
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A molecular survey of acute febrile illnesses reveals Plasmodium vivax infections in Kedougou, southeastern Senegal
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A Case of Plasmodium ovale wallikeri Infection in a Chinese Worker Returning from West Africa
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The Korean Journal of Parasitology.2013; 51(5): 557. CrossRef

10,428 View
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Original Article

Two new genotypes of Plasmodium vivax circumsporozoite protein found in the Republic of Korea: Weon-Gyu Kho, Yeong-Hong Park, Joon-Yong Chung, Jong-Pil Kim, Sung-Tae Hong, Won-Ja Lee, Tong-Soo Kim, Jong-Soo Lee; Korean J Parasitol 1999;37(4):265-270.
Published online December 31, 1999; DOI: https://doi.org/10.3347/kjp.1999.37.4.265

Abstract
PDF

The gene encoding Plasmodium vivax circumsporozoite protein (PvCSP) exhibits polymorphism in many geographical isolates. The present study was designed to investigate polymorphism in PvCSP gene of P. vivax isolates in Korea. Thirty isolates, obtained from indigenous cases in Yonchon-gun, Kyonggi-do in 1997, were subjected for sequencing and RFLP analysis of the repeat and post-repeat regions of PvCSP gene and two genotypes (SK-A and SK-B) were identified. The genotype of 19 isolates was SK-A and that of 11 isolates was SK-B. Although the number of 12-base repeats present in SK-A was three while two were found in a Chinese strain CH-5, the repeat sequence of SK-A was identical to that of CH-5 except for one base substitution. Compared with known data there was no identical isolates with SK-B, but the sequence of SK-B was similar to that of a North Korean (NK) isolate. These results indicate that two genotypes of PvCSP coexist in the present epidemic area of Korea and the present parasite may originate from East Asia. RFLP would be useful to classify genotypes of P. vivax population instead of gene sequencing.

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Exploring genetic polymorphisms among Plasmodium vivax isolates from the Thai-Myanmar borders using circumsporozoite protein (pvcsp) and ookinete surface protein (pvs25) encoding genes
Bashir Abdirahman Guled, Kesara Na-Bangchang, Wanna Chaijaroenkul
Parasitology Research.2024;[Epub] CrossRef
Genetic diversity of pvcsp and pvs25 in Plasmodium vivax isolates in malaria-endemic areas in Asia, Africa, and America: A systematic review
Abdirahman Guled Bashir, Chiajaroenkul Wanna, Na-Bangchang Kesara
African Journal of Pharmacy and Pharmacology.2023; 17(5): 73. CrossRef
Genetic Diversity of Plasmodium vivax Causing Epidemic Malaria in the Republic of Korea
Young Yil Bahk, Jeonga Kim, Seong Kyu Ahn, Byoung-Kuk Na, Jong-Yil Chai, Tong-Soo Kim
The Korean Journal of Parasitology.2018; 56(6): 545. CrossRef
Population genetics structure of Plasmodium vivax circumsporozoite protein during the elimination process in low and unstable malaria transmission areas, southeast of Iran
Samaneh Hemati Shabani, Sedigheh Zakeri, Akram Abouie Mehrizi, Yousef Mortazavi, Navid Dinparast Djadid
Acta Tropica.2016; 160: 23. CrossRef
Molecular genetic analysis of Plasmodium vivax isolates from Eastern and Central Sudan using pvcsp and pvmsp-3α genes as molecular markers
Albadawi Abdelbagi Talha, Sekineh Pirahmadi, Akram Abouie Mehrizi, Navid Dinparast Djadid, Bakri Y.M. Nour, Sedigheh Zakeri
Infection, Genetics and Evolution.2015; 32: 12. CrossRef
Molecular epidemiology of Plasmodium vivax in Latin America: polymorphism and evolutionary relationships of the circumsporozoite gene
Lilia González-Cerón, Jesus Martinez-Barnetche, Ciro Montero-Solís, Frida Santillán, Aida M Soto, Mario H Rodríguez, Benjamin J Espinosa, Octavio A Chávez
Malaria Journal.2013;[Epub] CrossRef
Microsatellite DNA Analysis Revealed a Drastic Genetic Change of Plasmodium vivax Population in the Republic of Korea During 2002 and 2003
Moritoshi Iwagami, Seung-Young Hwang, So-Hee Kim, So-Jung Park, Ga-Young Lee, Emilie Louise Akiko Matsumoto-Takahashi, Weon-Gyu Kho, Shigeyuki Kano, Shan Lv
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Yang Cheng, Daisuke Ito, Jetsumon Sattabongkot, Chae Seung Lim, Deok-Hoon Kong, Kwon-Soo Ha, Bo Wang, Takafumi Tsuboi, Eun-Taek Han
Malaria Journal.2013;[Epub] CrossRef
Population Structure and Transmission Dynamics of Plasmodium vivax in the Republic of Korea Based on Microsatellite DNA Analysis
Moritoshi Iwagami, Megumi Fukumoto, Seung-Young Hwang, So-Hee Kim, Weon-Gyu Kho, Shigeyuki Kano, Mehmet Ali Ozcel
PLoS Neglected Tropical Diseases.2012; 6(4): e1592. CrossRef
Trials for the co-expression of the merozoite surface protein-1 and circumsporozoite protein genes of Plasmodium vivax
Choonghee Lee, Kyung Won Chung, Tong-Soo Kim, Kyung-Mi Choi, Yien Kyoung Choi, Nam-Jun Chung, Ho-Gun Rhie, Ho-Sa Lee, Sung-Jae Lee, Hyeong-Woo Lee
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