1. The glucose uptake rate by Fasciola hepatica was a mean value of 9.62 ± 0.54 µM/hr/g, and total CO₂ production rate by the flukes averaged 24.28 ± 4.26 µM/hr/g wet wt. The relative specific activity of respiratory CO₂ showed a mean value of 79.89 ± 1.78 per cent. The rate of CO₂ production derived from medium C¹⁴-glucose was a mean of 19.55 ± 3.56 µM/hr/g of we wt. Therefore, the average value of 32.72 ± 4.8 percent of glucose utilized by the flukes from the medium C¹⁴-glucose was oxidized to respiratory CO₂.

2. The tissue concentration of glycogen in F. hepatica was a mean of 38.36 ± 2.91 mg/g or 3.84 ± 0.29 %/g of wet wt, and the turnover rate of glycogen pool was a mean of 1.6±0.22 %/hr or 0.65 ± 0.13 mg/hr/g. The average value of 37.26 ± 3.86 per cent of glucose utilized by the fluke from the medium C¹⁴-glucose was incorporated to the glycogen.

3. These data account for that approximately 70 per cent of the utilized glucose by the flukes participated in furnishing the oxidation into respiratory CO₂ and the synthetic process into glycogen.