Warning: mkdir(): Permission denied in /home/virtual/lib/view_data.php on line 81
Warning: fopen(upload/ip_log/ip_log_2024-12.txt): failed to open stream: No such file or directory in /home/virtual/lib/view_data.php on line 83
Warning: fwrite() expects parameter 1 to be resource, boolean given in /home/virtual/lib/view_data.php on line 84 Intestinal pathologic findings at early stage infection by Centrocestus armatus in albino rats
Intestinal pathologic findings at early stage infection by Centrocestus armatus in albino rats
S J Hong,*1J H Han,2C K Park,3 and S Y Kang1
1Department of Parasitology, Chung-Ang University College of Medicine, Dongjak-gu, Seoul 156-756, Korea.
Received January 27, 1997; Accepted March 20, 1997.
Abstract
This study was performed to observe intestinal pathology in early infection by Centrocestus armatus. The flukes were in the lowermost part of the intervillous space of the duodenum and jejunum from 1 day to 7 days postinfection (PI). The stroma of villi around the young fluke was edematous and infiltrated by inflammatory cells such as lymphocytes, plasma cells and eosinophils. The crypt became mildly hyperplastic and villi were moderately atrophied at 4 days PI. The intestinal lesion produced was confined to the areas around the fluke. The pathologic findings were not significantly different between 1,000 and 5,000 metacercariae infection groups. It is suggested that the lesion should be produced by mechanical destruction of the fluke on the enteroepithelial cells.
Figures
Figs. 1-4 Fig. 1. A young C. armatus is pinching the epithelium of the duodenum of a rat in group I at 1 day postinfection (PI). ×200. Fig. 2. At two days PI, a juvenile fluke is in a cave of a broadly fused villus in group I. ×100. Fig. 3. At four days PI, a fluke puts its oral sucker and circumoral spines into the crypt opening and embrasses the intestinal mucosa with its ventral concavity in the duodenum of a rat in group I. ×200. Fig. 4. At seven days PI, a fluke is found in the intervillous space of a fused villus, of which the tip is moderately edematous, in the jejunum in group II. ×100.
References
1.
Chai JY. Seoul J Med 1979;20:104–117.
2.
Hong SJ, Seo BS, Lee SH, Chai JY. A human case of Centrocestus armatus infection in Korea. Korean J Parasitol 1988;26(1):55–60.
3.
Hong SJ, Woo HC, Kim IT. [Study on Centrocestus armatus in Korea. I. Infection status of Zacco platypus and Z. temminckii with the metacercariae of C. armatus]. Korean J Parasitol 1989;27(1):41–46.
4.
Hong SJ, Woo HC, Chai JY, Chung SW, Lee SH, Seo BS. Study on Centrocestus armatus in Korea II Recovery rate, growth and development of worms in albino rats. Korean J Parasitol 1989;27(1):47–56.
5.
Kurokawa T. Tokyo Iji Shimshi 1935;1915:293–298.
6.
Lee SH, Noh TY, Sohn WM, Kho WG, Hong ST, Chai JY. [Chronological observation of intestinal lesions of rats experimentally infected with Echinostoma hortense. Korean J Parasitol 1990;28(1):45–52.
7.
Mishima T. Tokyo Iji Shinshi 1959;76:291–299.
8.
Rhee JK, Lee HI, Baek BK, Kim PG. [Survey On Encysted Cercariae Of Trematodes From Fresh-Water Fishes In Mangyeong Riverside Area]. Korean J Parasitol 1983;21(2):187–192.
9.
Rhee JK, Rim MH, Baek BK, Lee HI. [Survey On Encysted Cercaria Of Trematodes From Fresh-Water Fishes In Tongjin Riverside Areas In Korea. Korean J Parasitol 1984;22(2):190–202.
10.
Rho IH, et al. Chung-Ang J Med 1984;9:67–77.
11.
Ruitenberg EJ, Leenstra F, Elgersma A. Thymus dependence and independence of intestinal pathology in a Trichinella spiralis infection: a study in congenitally athymic (nude) mice. Br J Exp Pathol 1977;58(3):311–314.
PDF Links
Full text via DOI
Download Citation 
