Warning: fopen(/home/virtual/parasitol/journal/upload/ip_log/ip_log_2025-12.txt): failed to open stream: Permission denied in /home/virtual/lib/view_data.php on line 83
Warning: fwrite() expects parameter 1 to be resource, boolean given in /home/virtual/lib/view_data.php on line 84 Effects of Cryptosporidium baileyi infection on the bursa of Fabricius in chickens
In order to clarify the effect of cryptosporidiosis on immune response, histopathological changes associated with experimentally occurring bursal cryptosporidiosis in chickens were chronologically observed as the first step. A total of 150 2-day-old chickens was each inoculated orally with a single dose of 5 x 10(5) Cryptosporidium baileyi oocysts. The chickens showed a normal profile of oocyst shedding in droppings. The bursa indices throughout the experimental period indicated negligible reactions.
Numerous cryptosporidia occurred in the microvillous border of bursal epithelium between days 4 and 16 postinoculation (PI). Appearance of the most mast cells was followed by a dramatic loss of the protozoa in the bursa of Fabricius (BF). The distribution of the coccidium coincided with heterophil infiltration in the epithelium and adjacent lamina propria. The histopathological lesion was marked diffuse chronic superficial purulent bursitis with heterophil infiltration in the epithelium and adjacent lamina propria and mucosal epithelial hyperplasia. These results suggest that the bursitis may induce immunosuppressive effect.
Citations
Citations to this article as recorded by
Occurrence and molecular characterization of Cryptosporidium oocysts in chickens from Egypt, and a meta-analysis for Cryptosporidium infections in chickens worldwide Ahmed Essam, Bassem Elmishmishy, Enas Hammad, Salah Abu Elwafa, Ibrahim Abbas Veterinary Parasitology: Regional Studies and Reports.2025; 57: 101169. CrossRef
Consequence of Cryptosporidiosis on the immune response of vaccinated broiler chickens against Newcastle disease and/or avian influenza Abdelfattah H. Eladl, Hamed R. Hamed, Mostafa R. Khalil Veterinary Research Communications.2014; 38(3): 237. CrossRef
Effects of different inoculation routes on the parasitic sites of Cryptosporidium baileyi infection in chickens Lin Yuan, Wenchao Yan, Tianqi Wang, Weifeng Qian, Ke Ding, Longxian Zhang, Lifang Han, Xiaodong Shao Experimental Parasitology.2014; 145: 152. CrossRef
Reduced Serologic Response to Avian Influenza Vaccine in Specific-Pathogen-Free Chicks Inoculated with Cryptosporidium baileyi Y-X. Hao, J-M. Yang, C. He, Q. Liu, Tim A. McAllister Avian Diseases.2008; 52(4): 690. CrossRef
Cryptosporidium Infection in Domestic Geese (Anser anser f. domestica) Detected by In-situ Hybridization S. Chvala, K. Fragner, R. Hackl, M. Hess, H. Weissenböck Journal of Comparative Pathology.2006; 134(2-3): 211. CrossRef
Histomoniasis in the Bursa of Fabricius of Chickens Portia L. Cortes, R. P. Chin, Mark C. Bland, Rocio Crespo, H. L. Shivaprasad Avian Diseases.2004; 48(3): 711. CrossRef
Viability of preserved Cryptosporidium baileyi oocysts Chan-Gu Surl, Se-Min Kim, Hyeon-Cheol Kim The Korean Journal of Parasitology.2003; 41(4): 197. CrossRef
Cryptosporidiosis in birds — A review T. Sréter, I. Varga Veterinary Parasitology.2000; 87(4): 261. CrossRef
Immunosuppressive effect of Cryptosporidium baileyi infection on vaccination against Newcastle disease in chicks J K Rhee, H C Kim, S B Lee, S Y Yook The Korean Journal of Parasitology.1998; 36(2): 121. CrossRef
Immunosuppressive effect of Cryptosporidium baileyi infection on vaccination against avian infectious bronchitis in chicks J K Rhee, H J Yang, S Y Yook, H C Kim The Korean Journal of Parasitology.1998; 36(3): 203. CrossRef
Verification of immunosuppression in chicks caused by Cryptosporidium baileyi infection using Brucella abortus strain 1119-3 J K Rhee, H J Yang, H C Kim The Korean Journal of Parasitology.1998; 36(4): 281. CrossRef
Effect of Cryptosporidium baileyi infection on antibody response to sRBC in chickens J K Rhee, H C Kim, B K Park The Korean Journal of Parasitology.1998; 36(1): 33. CrossRef
Effects of Cryptosporidium muris (strain MCR) infection on gastric mucosal mast cells in mice J K Rhee, C G Surl, H C Kim The Korean Journal of Parasitology.1997; 35(4): 245. CrossRef
