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"Yun-Kyu Park"

Original Article

Functional characterization of glucose transporter 4 involved in glucose uptake in Clonorchis sinensis
Hojong Jun, Ernest Mazigo, Wang-Jong Lee, Yun-Kyu Park, Jin-Hee Han, Seok Ho Cha
Parasites Hosts Dis 2024;62(4):450-460.
Published online November 22, 2024
DOI: https://doi.org/10.3347/PHD.24051
Clonorchis sinensis, which causes clonorchiasis, is prevalent in East Asian countries and poses notable health risks, including bile duct complications. Although praziquantel is the primary treatment for the disease, the emerging resistance among trematodes highlights the need for alternative strategies. Understanding the nutrient uptake mechanisms in trematodes, including C. sinensis, is crucial for developing future effective treatments. This study aimed to characterize the function of C. sinensis glucose transporter 4 (CsGTP4) and determine its role in nutrient uptake employing synthesized cDNA of adult C. sinensis worms. The functional characterization of CsGTP4 involved injecting its cRNA into Xenopus laevis oocytes and analyzing the deoxy-D-glucose uptake levels. The results demonstrated that deoxy-D-glucose uptake depended on the deoxy-D-glucose incubation and CsGTP4 expression time, but not sodium-dependent. The concentration-dependent uptake followed the Michaelis–Menten equation, with a Km value of 2.7 mM and a Vmax value of 476 pmol/oocyte/h based on the Lineweaver–Burk analysis. No uptake of radiolabeled α-ketoglutarate, p-aminohippurate, taurocholate, arginine, or carnitine was observed. The uptake of deoxy-D-glucose by CsGTP4 was significantly inhibited by unlabeled glucose and galactose in a concentration-dependent manner. It was significantly inhibited under strongly acidic and basic conditions. These insights into the glucose uptake kinetics and pH dependency of CsGTP4 provide a deeper understanding of nutrient acquisition in trematodes. This study contributes to the development of novel antiparasitic agents, addressing a considerable socioeconomic challenge in affected regions.

Citations

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  • Clonorchis sinensis dopamine transporter (CsDAT) facilitates dopamine uptake
    Wang-Jong Lee, Sung-Jun Kim, Woon Kyu Lee, Jin-Hee Han, Seok Ho Cha
    Parasites, Hosts and Diseases.2025; 63(3): 215.     CrossRef
  • 2,396 View
  • 83 Download
  • 1 Web of Science
  • Crossref

Case Report

Two Imported Cases of Babesiosis with Complication or Co-Infection with Lyme Disease in Republic of Korea
Hea Yoon Kwon, Jae Hyoung Im, Yun-Kyu Park, Areum Durey, Jin-Soo Lee, Ji Hyeon Baek
Korean J Parasitol 2018;56(6):609-613.
Published online December 31, 2018
DOI: https://doi.org/10.3347/kjp.2018.56.6.609
Babesiosis, caused by Babesia microti and B. divergens, is transmitted by Ixodid ticks. Symptoms of babesiosis vary from a mild flu-like illness to acute, severe, and sometimes fatal and fulminant disease. In Korea, 7 imported babesiosis cases and 1 endemic case have been reported. We report 2 cases of severe babesiosis initially mistaken as malaria. The first patient was complicated by shock and splenic infarction, the other co-infected with Lyme disease. As the population traveling abroad increases every year, physicians should be aware of babesiosis which mimics malaria, co-infection with other diseases, and its complications.

Citations

Citations to this article as recorded by  Crossref logo
  • Imported parasitic diseases in the Republic of Korea: status and issues
    Jong-Yil Chai
    Journal of the Korean Medical Association.2025; 68(1): 52.     CrossRef
  • Splenic Infarction in Babesiosis: A Case Series
    Kaetlyn Arant, Ty Agaisse, Athanasios Vassilopoulos, Sassine Ghanem, Michael Santos
    Journal of Brown Hospital Medicine.2025;[Epub]     CrossRef
  • Detection of US and Kobe‐type Babesia microti in ticks collected from small mammals of the Republic of Korea
    Tae Yun Kim, Seong Yoon Kim, Jiye Seo, Hee IL Lee, Wook‐Gyo Lee, Hyunwoo Kim
    Entomological Research.2024;[Epub]     CrossRef
  • Current Status of Trypanosoma grosi and Babesia microti in Small Mammals in the Republic of Korea
    Hyun Jung Kim, BoGyeong Han, Hee-Il Lee, Jung-Won Ju, Hyun-Il Shin
    Animals.2024; 14(7): 989.     CrossRef
  • Imported human babesiosis in the Republic of Korea, 2019: two case reports
    Hyun Jung Kim, Min Jae Kim, Hyun-Il Shin, Jung-Won Ju, Hee-Il Lee
    Parasites, Hosts and Diseases.2023; 61(1): 72.     CrossRef
  • iSeq 100 for metagenomic pathogen screening in ticks
    Ju Yeong Kim, Myung-hee Yi, Alghurabi Areej Sabri Mahdi, Tai-Soon Yong
    Parasites & Vectors.2021;[Epub]     CrossRef
  • Molecular evidence of zoonotic Babesia species, other than B. microti, in ixodid ticks collected from small mammals in the Republic of Korea
    Tae Yun Kim, Seong Yoon Kim, Tae‐Kyu Kim, Hee IL Lee, Shin‐Hyeong Cho, Wook‐Gyo Lee, Hyunwoo Kim
    Veterinary Medicine and Science.2021; 7(6): 2427.     CrossRef
  • Interactions between Babesia microti merozoites and rat kidney cells in a short-term in vitro culture and animal model
    Marta Albertyńska, Hubert Okła, Krzysztof Jasik, Danuta Urbańska-Jasik, Przemysław Pol
    Scientific Reports.2021;[Epub]     CrossRef
  • A Review of Zoonotic Babesiosis as an Emerging Public Health Threat in Asia
    Sabir Hussain, Abrar Hussain, Muhammad Umair Aziz, Baolin Song, Jehan Zeb, David George, Jun Li, Olivier Sparagano
    Pathogens.2021; 11(1): 23.     CrossRef
  • Splenic Complications ofBabesia microtiInfection in Humans: A Systematic Review
    Igor Dumic, Cristian Madrid, Libardo Rueda Prada, Charles W. Nordstrom, Pahnwat Tonya Taweesedt, Poornima Ramanan
    Canadian Journal of Infectious Diseases and Medical Microbiology.2020; 2020: 1.     CrossRef
  • A Practical Approach to the Diagnosis of Lyme Borreliosis: From Clinical Heterogeneity to Laboratory Methods
    Giusto Trevisan, Serena Bonin, Maurizio Ruscio
    Frontiers in Medicine.2020;[Epub]     CrossRef
  • 8,817 View
  • 159 Download
  • 11 Web of Science
  • Crossref

Original Article

Survey on Intestinal Helminthic Infection Status of Students in Two Counties, Hadong-gun and Goseong-gun, Korea
Young Yil Bahk, Yun-Kyu Park, Byoung-Kuk Na, Woon-Mok Sohn, Sung-Jong Hong, Jong-Yil Chai, Tong-Soo Kim
Korean J Parasitol 2018;56(4):335-339.
Published online August 31, 2018
DOI: https://doi.org/10.3347/kjp.2018.56.4.335
This study was conducted to investigate the prevalence of intestinal parasites among students from Goseonggun, Gangwon-do and Hadong-gun, Gyeongsangnam-do as typical low and high endemic counties. From May to July 2017, a total of 2,033 fecal samples were collected at 27 elementary, 10 junior high, and 8 high schools from 2 counties and examined by the Kato-Katz technique for egg-positive surveys (Collection rate: 37.02% [2,033/5,492]). Of the participants examined, 13 (0.64%) were found to harbor eggs of 3 parasitic species, Trichuris trichiura, Clonorchis sinensis and Metagonimus yokogawai. Based on the regional distribution, the egg-positive rate in Goseong-gun was 0% (0/550) and that in Hadong-gun was 0.88% (13/1,483). The positive rates for C. sinensis, M. yokogawai, and T. trichiura in Hadonggun were 0.20% (3/1,483), 0.61% (9/1,483), and 0.07% (1/1,483), respectively. The present survey showed that the prevalence of parasitic infection among students is currently very low even in remote, previously endemic areas, and the present status of parasitic diseases can be summarized as some transmission of fish/food-borne trematodes. Thus, it is necessary to carefully, continuously monitor the trematode infection status, particularly of C. sinensis and M. yokogawai.

Citations

Citations to this article as recorded by  Crossref logo
  • The spatial-temporal risk profiling of Clonorchis sinensis infection over 50 years implies the effectiveness of control programs in South Korea: a geostatistical modeling study
    Hai-Yan Xiao, Jong-Yil Chai, Yue-Yi Fang, Ying-Si Lai
    The Lancet Regional Health - Western Pacific.2023; 33: 100697.     CrossRef
  • Global prevalence of 4 neglected foodborne trematodes targeted for control by WHO: A scoping review to highlight the gaps
    Rachel Tidman, Kaushi S. T. Kanankege, Mathieu Bangert, Bernadette Abela-Ridder, Paul R. Torgerson
    PLOS Neglected Tropical Diseases.2023; 17(3): e0011073.     CrossRef
  • Risk Factors for Clonorchis sinensis Infection in Residents of Binyang, Guangxi: A Cross-Sectional and Logistic Analysis Study
    Meng Xu, Yanyan Jiang, Jianhai Yin, Shengkui Cao, Yujuan Shen, Jianping Cao
    Frontiers in Public Health.2021;[Epub]     CrossRef
  • Currently Available Monitoring and Surveillance Systems for Taenia spp., Echinococcus spp., Schistosoma spp., and Soil-Transmitted Helminths at the Control/Elimination Stage: A Systematic Review
    Ganna Saelens, Sarah Gabriël
    Pathogens.2020; 9(1): 47.     CrossRef
  • Status of common parasitic diseases in Korea in 2019
    Sun Huh
    Journal of the Korean Medical Association.2019; 62(8): 437.     CrossRef
  • Blood Pressure and the Risk of Death From Non-cardiovascular Diseases: A Population-based Cohort Study of Korean Adults
    Jeoungbin Choi, Jieun Jang, Yoonsuk An, Sue K. Park
    Journal of Preventive Medicine and Public Health.2018; 51(6): 298.     CrossRef
  • 7,300 View
  • 132 Download
  • 6 Web of Science
  • Crossref

Brief Communications

Monitoring of Noxious Protozoa for Management of Natural Water Resources
Young Yil Bahk, Pyo Yun Cho, Sung Kyu Ahn, Sangjung Park, Won Hwa Jheong, Yun-Kyu Park, Ho-Joon Shin, Sang-Seob Lee, Okjae Rhee, Tong-Soo Kim
Korean J Parasitol 2018;56(2):205-210.
Published online April 30, 2018
DOI: https://doi.org/10.3347/kjp.2018.56.2.205
Waterborne parasitic protozoa, particularly Giardia lamblia and Cryptosporidium spp., are common causes of diarrhea and gastroenteritis worldwide. The most frequently identified source of infestation is water, and exposure involves either drinking water or recreation in swimming pools or natural bodies of water. In practice, studies on Cryptosporidium oocysts and Giardia cysts in surface water are challenging owing to the low concentrations of these microorganisms because of dilution. In this study, a 3-year monitoring of Cryptosporidium parvum, Giardia lamblia, and Naegleria fowleri was conducted from August 2014 to June 2016 at 5 surface water sites including 2 lakes, 1 river, and 2 water intake plants. A total of 50 water samples of 40 L were examined. Cryptosporidium oocysts were detected in 22% of samples and Giardia cysts in 32%. Water at the 5 sampling sites was all contaminated with Cryptosporidium oocysts (0-36/L), Giardia cysts (0-39/L), or both. The geometric mean concentrations of Cryptosporidium and Giardia were 1.14 oocysts/L and 4.62 cysts/L, respectively. Thus, effective monitoring plans must take into account the spatial and temporal parameters of contamination because they affect the prevalence and distribution of these protozoan cysts in local water resources.

Citations

Citations to this article as recorded by  Crossref logo
  • Cryptosporidium and cryptosporidiosis: An update of Asian perspectives in humans, water and food, 2015–2025
    Shahira Abdelaziz Ali Ahmed, Sonia Boughattas, Mohammad Reza Mahmoudi, Huma Khan, Simuzar Mamedova, Ardra Namboodiri, Frederick R. Masangkay, Panagiotis Karanis
    Current Research in Parasitology & Vector-Borne Diseases.2025; 8: 100311.     CrossRef
  • Recent progress of functionalized nanomaterials-based biosensing for monitoring of food- and water-borne pathogens
    Piyush Dey, Mohd Jamshaiya Raza, Alisha Khera, Akanksha Sharma, Akhil Khajuria, Ankur Pandey, Chandra Mouli Pandey, Rakesh Kumar Sharma, Gurpal Singh, Ravi Pratap Barnwal
    Environmental Nanotechnology, Monitoring & Management.2024; 21: 100914.     CrossRef
  • Performance of sewage treatment technologies for the removal of Cryptosporidium sp. and Giardia sp.: Toward water circularity
    Pilar Suarez, José Luis Alonso, Gloria Gómez, Gladys Vidal
    Journal of Environmental Management.2022; 324: 116320.     CrossRef
  • Incorporating Microbial Species Interaction in Management of Freshwater Toxic Cyanobacteria: A Systems Science Challenge
    Aabir Banerji, Kasey Benesh
    Ecologies.2022; 3(4): 570.     CrossRef
  • 9,991 View
  • 153 Download
  • 6 Web of Science
  • Crossref
Discovery of Parasite Eggs in Archeological Residence during the 15th Century in Seoul, Korea
Pyo Yeon Cho, Jung-Min Park, Myeong-Ki Hwang, Seo Hye Park, Yun-Kyu Park, Bo-Young Jeon, Tong-Soo Kim, Hyeong-Woo Lee
Korean J Parasitol 2017;55(3):357-361.
Published online June 30, 2017
DOI: https://doi.org/10.3347/kjp.2017.55.3.357
During civil engineering construction near Sejong-ro, Jongro-ku, Seoul, cultural sites were found that are thought to have been built in the 15th century. This area was home to many different people as well as the leaders of the Yi dynasty. To gain further insight into the life styles of the inhabitants of the old capital, soil samples were collected from various areas such as toilets, water foundations, and drainage ways. Parasite eggs were examined by microscopy after 5 g soil samples were rehydrated in 0.5% trisodium phosphate solution. A total of 662 parasite eggs from 7 species were found. Species with the highest number of eggs found were Ascaris lumbricoides (n=483), followed by Trichuris trichiura (138), Trichuris vulpis (21), Fasciola hepatica (8), Clonorchis sinensis (6), Paragonimus westermani (4), and Metagonimus yokogawai (2). These findings indirectly indicate the food habits of the people in Yi dynasty.

Citations

Citations to this article as recorded by  Crossref logo
  • Clonorchis sinensis and Cholangiocarcinoma
    Eun-Min Kim, Sung-Tae Hong
    Journal of Korean Medical Science.2025;[Epub]     CrossRef
  • Paleoparasitology research on ancient helminth eggs and larvae in the Republic of Korea
    Jong-Yil Chai, Min Seo, Dong Hoon Shin
    Parasites, Hosts and Diseases.2023; 61(4): 345.     CrossRef
  • Green vegetable juice as a potential source of human fascioliasis in Korea
    Sungim Choi, Sunghee Park, Sooji Hong, Hyejoo Shin, Bong-Kwang Jung, Min Jae Kim
    One Health.2022; 15: 100441.     CrossRef
  • Opisthorchis felineus as the basis for the reconstruction of migrations using archaeoparasitological materials
    Sergey Slepchenko
    Journal of Archaeological Science: Reports.2020; 33: 102548.     CrossRef
  • Archaeoparasitological Analysis of Samples from the Cultural Layer of Nadym Gorodok dated Back to the 14th-Late 18th Centuries
    Sergey Mikhailovich Slepchenko, Oleg Viktorovich Kardash, Vyacheslav Sergeyevich Slavinsky, Sergey Nikolaevich Ivanov, Rakultseva Daria Sergeyevna, Alexander Alekseevich Tsybankov, Dong Hoon Shin
    The Korean Journal of Parasitology.2019; 57(6): 567.     CrossRef
  • 9,219 View
  • 138 Download
  • 5 Web of Science
  • Crossref

Case Report

Ectopic Human Fasciola hepatica Infection by an Adult Worm in the Mesocolon
Ah Jin Kim, Chang Hwan Choi, Sun Keun Choi, Yong Woon Shin, Yun-Kyu Park, Lucia Kim, Suk Jin Choi, Jee Young Han, Joon Mee Kim, Young Chae Chu, In Suh Park
Korean J Parasitol 2015;53(6):725-730.
Published online December 31, 2015
DOI: https://doi.org/10.3347/kjp.2015.53.6.725
We report here an ectopic case of Fasciola hepatica infection confirmed by recovery of an adult worm in the mesocolon. A 56-year-old female was admitted to our hospital with discomfort and pain in the left lower quadrant of the abdomen. Abdominal CT showed 3 abscesses in the left upper quadrant, mesentery, and pelvic cavity. On surgical exploration, abscess pockets were found in the mesocolon of the sigmoid colon and transverse colon. A leaf-like worm found in the abscess pocket of the mesocolon of the left colon was diagnosed as an adult fluke of F. hepatica. Histologically, numerous eggs of F. hepatica were noted with acute and chronic granulomatous inflammations in the subserosa and pericolic adipose tissues. Conclusively, a rare case of ectopic fascioliasis has been confirmed in this study by the adult worm recovery of F. hepatica in the mesocolon.

Citations

Citations to this article as recorded by  Crossref logo
  • Molecular identification of Fasciola and Dicrocoelium species isolates in ruminants livestock from Kashan and Arak in center of Iran
    Mohsen Arbabi, Hossein Hooshyar, Mahdi Delavari
    Journal of Parasitic Diseases.2025; 49(2): 453.     CrossRef
  • Hepatic and Extrahepatic Fascioliasis Mimicking Colon Cancer with Hepatic Metastasis
    Youe Ree Kim, Young Hwan Lee, Kwon-Ha Yoon
    Korean Journal of Abdominal Radiology.2022; 6(1): 51.     CrossRef
  • Phylogenetic Characteristics of Fasciola hepatica Isolated from a Korean Patient
    Mi Jin Jeong, Jae Kyun Park, Hak Sun Yu
    The Korean Journal of Parasitology.2022; 60(5): 367.     CrossRef
  • Prevalence of Schistosoma japonicum infection in water buffaloes in selected areas in Davao del Norte and Davao de Oro, the Philippines
    Rohani C. Navarro, Aleyla E. de Cadiz, Jordan M. Fronda, Lynnell Alexie D. Ong, Vicente Y. Belizario Jr.
    International Journal of One Health.2021; 7(1): 12.     CrossRef
  • Ascariasis Presenting as Hematoma in the Sigmoid Mesocolon: A Case Report
    Ji-Eun Kim, Kyung Eun Bae, Hyun-Jung Kim, Byung-Noe Bae, Ji Hae Lee, Mi-Jin Kang, Ji-Young Kim, Jae Hyung Kim
    Journal of the Korean Society of Radiology.2020; 81(4): 1013.     CrossRef
  • Parasitological monitoring of European bison (Bison bonasus) from three forests of north-eastern Poland between 2014 and 2016
    Michał K. Krzysiak, Aleksander W. Demiaszkiewicz, Magdalena Larska, Jarosław Tomana, Krzysztof Anusz
    Journal of Veterinary Research.2020; 64(1): 103.     CrossRef
  • NumerousFasciolaplasminogen-binding proteins may underlie blood-brain barrier leakage and explain neurological disorder complexity and heterogeneity in the acute and chronic phases of human fascioliasis
    J. González-Miguel, M. A. Valero, M. Reguera-Gomez, C. Mas-Bargues, M. D. Bargues, F. Simón, S. Mas-Coma
    Parasitology.2019; 146(3): 284.     CrossRef
  • Highlights of human ectopic fascioliasis: a systematic review
    Ali Taghipour, Leila Zaki, Ali Rostami, Masoud Foroutan, Fatemeh Ghaffarifar, Atefeh Fathi, Amir Abdoli
    Infectious Diseases.2019; 51(11-12): 785.     CrossRef
  • A Case of Ectopic Peritoneal Paragonimiasis Mimicking Diverticulitis or Abdominal Abscess
    Min Jae Kim, Sung-Han Kim, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Jun Hee Woo, Yong Sik Yoon, Kyung Won Kim, Jaeeun Cho, Jong-Yil Chai, Yong Pil Chong
    The Korean Journal of Parasitology.2017; 55(3): 313.     CrossRef
  • 12,230 View
  • 159 Download
  • 8 Web of Science
  • Crossref

Original Articles

Relationship between Antibody-Positive Rate against Plasmodium vivax Circumsporozoite Protein and Incidence of Malaria
Hyeong-Woo Lee, Yoon-Joong Kang, Shin-Hyeong Cho, Byoung-Kuk Na, Jhang Ho Pak, Ho-Woo Nam, Yun-Kyu Park, Youngjoo Sohn, Tong-Soo Kim
Korean J Parasitol 2015;53(2):169-175.
Published online April 22, 2015
DOI: https://doi.org/10.3347/kjp.2015.53.2.169
The relationship between anti-Plasmodium vivax circumsporozoite protein (CSP) antibody levels and the prevalence of malaria in epidemic areas of South Korea was evaluated. Blood samples were collected from inhabitants of Gimpo-si (city), Paju-si, and Yeoncheon-gun (county) in Gyeonggi-do (province), as well as Cheorwon-gun in Gangwon-do from November to December 2004. Microscopic examinations were used to identify malaria parasites. ELISA was used to quantitate anti-circumsporozoite protein (CSP) antibodies against P. vivax. A total of 1,774 blood samples were collected. The overall CSP-ELISA-positive rate was 7.7% (n=139). The annual parasite incidences (APIs) in these areas gradually decreased from 2004 to 2005 (1.09 and 0.80, respectively). The positive rate in Gimpo (10.4%, 44/425) was the highest identified by CSP-ELISA. The highest API was found in Yeoncheon, followed by Cheorwon, Paju, and Gimpo in both years. The positive rates of CSP-ELISA were closely related to the APIs in the study areas. These results suggest that seroepidemiological studies based on CSP may be helpful in estimating the malaria prevalence in certain areas. In addition, this assay can be used to establish and evaluate malaria control and eradication programs in affected areas.

Citations

Citations to this article as recorded by  Crossref logo
  • Updated global distribution of Plasmodium vivax circumsporozoite protein variants and their correlation with vector susceptibility: A systematic review and meta-analysis
    Marrara P. Sampaio, Marcelo Cerilo-Filho, Yasmin de A․G․do Amaral, Maria Naely G. Almeida, Rayanne I. Correa, Dulce J.V. Fernando, Nathália F. Reis, Leonardo A. Miceli, José R.S. Silva, Luciane M. Storti-Melo, Andréa R.S. Baptista, Ricardo L.D. Machado
    Acta Tropica.2025; 261: 107508.     CrossRef
  • Using Serological Markers for the Surveillance of Plasmodium vivax Malaria: A Scoping Review
    Lejla Kartal, Ivo Mueller, Rhea J. Longley
    Pathogens.2023; 12(6): 791.     CrossRef
  • 9,647 View
  • 124 Download
  • 2 Web of Science
  • Crossref
Evaluation of the Accuracy of the EasyTest™ Malaria Pf/Pan Ag, a Rapid Diagnostic Test, in Uganda
Chom-Kyu Chong, Pyo Yun Cho, Byoung-Kuk Na, Seong Kyu Ahn, Jin Su Kim, Jin-Soo Lee, Sung-Keun Lee, Eun-Taek Han, Hak-Yong Kim, Yun-Kyu Park, Seok Ho Cha, Tong-Soo Kim
Korean J Parasitol 2014;52(5):501-505.
Published online October 22, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.5.501

In recent years, rapid diagnostic tests (RDTs) have been widely used for malaria detection, primarily because of their simple operation, fast results, and straightforward interpretation. The Asan EasyTest™ Malaria Pf/Pan Ag is one of the most commonly used malaria RDTs in several countries, including Korea and India. In this study, we tested the diagnostic performance of this RDT in Uganda to evaluate its usefulness for field diagnosis of malaria in this country. Microscopic and PCR analyses, and the Asan EasyTest™ Malaria Pf/Pan Ag rapid diagnostic test, were performed on blood samples from 185 individuals with suspected malaria in several villages in Uganda. Compared to the microscopic analysis, the sensitivity of the RDT to detect malaria infection was 95.8% and 83.3% for Plasmodium falciparum and non-P. falciparum, respectively. Although the diagnostic sensitivity of the RDT decreased when parasitemia was ≤500 parasites/?l, it showed 96.8% sensitivity (98.4% for P. falciparum and 93.8% for non-P. falciparum) in blood samples with parasitemia ≥100 parasites/?l. The specificity of the RDT was 97.3% for P. falciparum and 97.3% for non-P. falciparum. These results collectively suggest that the accuracy of the Asan EasyTest™ Malaria Pf/Pan Ag makes it an effective point-of-care diagnostic tool for malaria in Uganda.

Citations

Citations to this article as recorded by  Crossref logo
  • Asymptomatic malaria infection, associated factors and accuracy of diagnostic tests in a historically high transmission setting in Northern Uganda
    Bosco B. Agaba, Simon P. Rugera, Ruth Mpirirwe, Martha Atekat, Samuel Okubal, Khalid Masereka, Miseal Erionu, Bosco Adranya, Gertrude Nabirwa, Patrick B. Odong, Yasin Mukiibi, Isaac Ssewanyana, Susan Nabadda, Enoch Muwanguzi
    Malaria Journal.2022;[Epub]     CrossRef
  • Genetic diversity of Plasmodium vivax and Plasmodium falciparum lactate dehydrogenases in Myanmar isolates
    Jinyoung Lee, Tae Im Kim, Hương Giang Lê, Won Gi Yoo, Jung-Mi Kang, Seong-Kyu Ahn, Moe Kyaw Myint, Khin Lin, Tong-Soo Kim, Byoung-Kuk Na
    Malaria Journal.2020;[Epub]     CrossRef
  • Limitations of rapid diagnostic tests in malaria surveys in areas with varied transmission intensity in Uganda 2017-2019: Implications for selection and use of HRP2 RDTs
    Agaba B. Bosco, Joaniter I. Nankabirwa, Adoke Yeka, Sam Nsobya, Karryn Gresty, Karen Anderson, Paul Mbaka, Christiane Prosser, David Smith, Jimmy Opigo, Rhoda Namubiru, Emmanuel Arinaitwe, John Kissa, Samuel Gonahasa, Sungho Won, Bora Lee, Chae Seung Lim,
    PLOS ONE.2020; 15(12): e0244457.     CrossRef
  • An Update on Malaria Rapid Diagnostic Tests
    Avinash N. Mukkala, Jason Kwan, Rachel Lau, David Harris, Dylan Kain, Andrea K. Boggild
    Current Infectious Disease Reports.2018;[Epub]     CrossRef
  • Comparative Assessment of Diagnostic Performances of Two Commercial Rapid Diagnostic Test Kits for Detection of Plasmodium spp. in Ugandan Patients with Malaria
    Young Yil Bahk, Seo Hye Park, Woojoo Lee, Kyoung Jin, Seong Kyu Ahn, Byoung-Kuk Na, Tong-Soo Kim
    The Korean Journal of Parasitology.2018; 56(5): 447.     CrossRef
  • An Evaluation of Active Case Detection in Malaria Control Program in Kiyuni Parish of Kyankwanzi District, Uganda
    Young Yil Bahk, Pyo Yun Cho, Seong Kyu Ahn, Woo-Joo Lee, Tong-Soo Kim
    The Korean Journal of Parasitology.2018; 56(6): 625.     CrossRef
  • Comparison of the diagnostic performance of microscopic examination with nested polymerase chain reaction for optimum malaria diagnosis in Upper Myanmar
    Jung-Mi Kang, Pyo-Yun Cho, Mya Moe, Jinyoung Lee, Hojong Jun, Hyeong-Woo Lee, Seong Kyu Ahn, Tae Im Kim, Jhang Ho Pak, Moe Kyaw Myint, Khin Lin, Tong-Soo Kim, Byoung-Kuk Na
    Malaria Journal.2017;[Epub]     CrossRef
  • A Cluster Randomised Trial Introducing Rapid Diagnostic Tests into Registered Drug Shops in Uganda: Impact on Appropriate Treatment of Malaria
    Anthony K. Mbonye, Pascal Magnussen, Sham Lal, Kristian S. Hansen, Bonnie Cundill, Clare Chandler, Siân E. Clarke, Roly D Gosling
    PLOS ONE.2015; 10(7): e0129545.     CrossRef
  • 10,715 View
  • 111 Download
  • 10 Web of Science
  • Crossref

Brief Communication

Phylogenetic Relationships of 3 Korean Neodiplostomum Species (Digenea: Neodiplostomidae) Based on Partial CO1 Gene
Kyoung-Ho Pyo, Jo Woon Yi Lee, Jin-Ju Lee, Yun-Kyu Park, Eun-Hee Shin, Jong-Yil Chai
Korean J Parasitol 2014;52(3):325-329.
Published online June 26, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.3.325

The phylogenetic relationships of the 3 Neodiplostomum spp. (Digenea: Neodiplostomidae) occurring in Korea (N. seoulense, N. leei, and N. boryongense) were analyzed using the partial mitochondrial cytochrome c oxidase subunit 1 (CO1) gene. The adult flukes were recovered from Sprague-Dawley rats (N. seoulense) and newborn chicks (N. leei and N. boryongense) experimentally infected with the neodiplostomula from the grass snake, Rhabdophis tigrinus tigrinus. The genomic DNA was amplified using specific primers, and the sequence of CO1 was obtained. According to the results, the pairwise similarity was 96.1% between N. boryongense and N. seoulense, but was 95.0% between N. boryongense and N. leei and 94.2% between N. leei and N. seoulense. The results demonstrated a closer phylogenetic relationship between N. seoulense and N. boryongense. This high relationship of N. seoulense and N. boryongense may be related to their similar morphologic features including the limited distribution of vitellaria and the presence of a genital cone. N. leei is distinct on the other hand with an extensive distribution of vitellaria and the absence of a genital cone.

Citations

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  • Neodiplostomum cf. seoulense (Seo, Rim, Lee, 1964) sensu Pyo et al., 2014 (Trematoda: Diplostomidae Poirier, 1886): morphology, life cycle, and phylogenetic relationships
    A. V. Izrailskaia, V. V. Besprozvannykh
    Journal of Helminthology.2023;[Epub]     CrossRef
  • Paraphyly of Conodiplostomum Dubois, 1937
    Petr Heneberg, Jiljí Sitko, Miroslav Těšínský
    Parasitology International.2020; 76: 102033.     CrossRef
  • New data on Neodiplostomum americanum Chandler and Rausch, 1947 (Digenea: Diplostomidae), in the Great Horned Owl Bubo virginianus Gmelin, 1788 and the Eastern Screech Owl Megascops asio Linnaeus, 1758 in Mississippi, USA
    Ethan T. Woodyard, Thomas G. Rosser, Matt J. Griffin
    Parasitology Research.2017; 116(8): 2075.     CrossRef
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Original Article

Seroprevalence of Plasmodium vivax in the Republic of Korea (2003-2005) using Indirect Fluorescent Antibody Test
Tong-Soo Kim, Yoon-Joong Kang, Won-Ja Lee, Byoung-Kuk Na, Sung-Ung Moon, Seok Ho Cha, Sung-Keun Lee, Yun-Kyu Park, Jhang-Ho Pak, Pyo Yun Cho, Youngjoo Sohn, Hyeong-Woo Lee
Korean J Parasitol 2014;52(1):1-7.
Published online February 19, 2014
DOI: https://doi.org/10.3347/kjp.2014.52.1.1

Plasmodium vivax reemerged in the Republic of Korea (ROK) in 1993, and is likely to continue to affect public health. The purpose of this study was to measure levels of anti-P. vivax antibodies using indirect fluorescent antibody test (IFAT) in border areas of ROK, to determine the seroprevalence of malaria (2003-2005) and to plan effective control strategies. Blood samples of the inhabitants in Gimpo-si, Paju-si, and Yeoncheon-gun (Gyeonggi-do), and Cheorwon-gun (Gangwon-do) were collected and kept in Korea Centers for Disease Control and Prevention (KCDC). Out of a total of 1,774 serum samples tested, the overall seropositivity was 0.94% (n=17). The seropositivity was the highest in Paju-si (1.9%, 7/372), followed by Gimpo-si (1.4%, 6/425), Yeoncheon-gun (0.67%, 3/451), and Cheorwon-gun (0.19%, 1/526). The annual parasite incidence (API) in these areas gradually decreased from 2003 to 2005 (1.69, 1.09, and 0.80 in 2003, 2004, and 2005, respectively). The highest API was found in Yeoncheon-gun, followed by Cheorwon-gun, Paju-si, and Gimpo-si. The API ranking in these areas did not change over the 3 years. The seropositivity of Gimpo-si showed a strong linear relationship with the API of 2005 (r=0.9983, P=0.036). Seropositivity data obtained using IFAT may be useful for understanding malaria prevalence of relevant years, predicting future transmission of malaria, and for establishing and evaluating malaria control programs in affected areas.

Citations

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  • Using Serological Markers for the Surveillance of Plasmodium vivax Malaria: A Scoping Review
    Lejla Kartal, Ivo Mueller, Rhea J. Longley
    Pathogens.2023; 12(6): 791.     CrossRef
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Case Report

A Case of Vivax Malaria Complicated by Adult Respiratory Distress Syndrome and Successful Management with Extracorporeal Membrane Oxygenation
Hyun-Jung Lee, Ji-Hyeon Baek, Myoung-Hun Chae, Hoyeon Joo, Jin-Soo Lee, Moon-Hyun Chung, Yun-Kyu Park, Joung-Teak Kim
Korean J Parasitol 2013;51(5):551-555.
Published online October 31, 2013
DOI: https://doi.org/10.3347/kjp.2013.51.5.551

Complicated malaria is mainly caused by Plasmodium falciparum, but, increasingly, Plasmodium vivax is also being reported as a cause. Since the reemergence of indigenous vivax malaria in 1993, cases of severe malaria have been steadily reported in Korea. Herein, we report a case of vivax malaria complicated by adult respiratory distress syndrome (ARDS) that was successfully managed with extracorporeal membrane oxygenation (ECMO). A 59-year-old man presented at our hospital with fever and abdominal pain, which had persisted for 10 days. On admission, the patient had impaired consciousness, shock, hypoxia and haziness in both lungs, jaundice, thrombocytopenia and disseminated intravascular coagulation, metabolic acidosis, and acute kidney injury. A peripheral blood smear and a rapid diagnostic test verified P. vivax mono-infection. Ten hours after admission, hypoxia became more severe, despite providing maximal ventilatory support. The administration of antimalarial agents, ECMO, and continuous venovenous hemofiltration resulted in an improvement of his vital signs and laboratory findings. He was discharged from the hospital 7 weeks later, without any sequelae.

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    Fran Prenen, Bram De Pauw, Sofie Knoops, Emilie Pollenus, Hendrik Possemiers, Johan Van Weyenbergh, Philippe E. Van den Steen
    Malaria Journal.2025;[Epub]     CrossRef
  • Membrana de oxigenación extracorpórea (ECMO) como terapia puente a la cirugía en paciente con síndrome de distrés respiratorio agudo (SDRA) debido a la rotura de un quiste hidatídico pulmonar
    María Teresa Gómez-Hernández, Ernest J. Martínez, Marta G. Fuentes, Marta Paz, Israel Rodríguez, Nuria M. Novoa, Marcelo F. Jiménez
    Archivos de Bronconeumología.2021; 57(7): 503.     CrossRef
  • Extracorporeal membrane oxygenation (ECMO) as bridge therapy to surgery in a patient with acute respiratory distress syndrome (ARDS) due to rupture of a pulmonary hydatid cyst
    María Teresa Gómez-Hernández, Ernest J. Martínez, Marta G. Fuentes, Marta Paz, Israel Rodríguez, Nuria M. Novoa, Marcelo F. Jiménez
    Archivos de Bronconeumología (English Edition).2021; 57(7): 503.     CrossRef
  • Prevalence and risk factors related to poor outcome of patients with severe Plasmodium vivax infection: a systematic review, meta-analysis, and analysis of case reports
    Manas Kotepui, Kwuntida Uthaisar Kotepui, Giovanni De Jesus Milanez, Frederick Ramirez Masangkay
    BMC Infectious Diseases.2020;[Epub]     CrossRef
  • The emergence of pathogenic TNF/iNOS producing dendritic cells (Tip-DCs) in a malaria model of acute respiratory distress syndrome (ARDS) is dependent on CCR4
    Bruno Galvão-Filho, Júlia Teixeira de Castro, Maria Marta Figueiredo, Claudio Gonçalves Rosmaninho, Lis Ribeiro do Valle Antonelli, Ricardo Tostes Gazzinelli
    Mucosal Immunology.2019; 12(2): 312.     CrossRef
  • Monocyte-derived dendritic cells in malaria
    Isabella C Hirako, Patrícia A Assis, Bruno Galvão-Filho, Andrew D Luster, Lis RV Antonelli, Ricardo T Gazzinelli
    Current Opinion in Microbiology.2019; 52: 139.     CrossRef
  • Could Heme Oxygenase-1 Be a New Target for Therapeutic Intervention in Malaria-Associated Acute Lung Injury/Acute Respiratory Distress Syndrome?
    Marcelo L. M. Pereira, Claudio R. F. Marinho, Sabrina Epiphanio
    Frontiers in Cellular and Infection Microbiology.2018;[Epub]     CrossRef
  • Development of Visually Improved Loop Mediated Isothermal Amplification for the Diagnosis of Plasmodium vivax Malaria in a Tertiary Hospital in Chandigarh, North India
    Hargobinder Kaur, Rakesh Sehgal, Devendra Bansal, Ali A. Sultan, Ashish Bhalla, Sunit C. Singhi
    The American Journal of Tropical Medicine and Hygiene.2018; 98(5): 1374.     CrossRef
  • Severe Plasmodium vivax infection in Korea
    Jae Hyoung Im, Hea Yoon Kwon, JiHyeon Baek, Seong Wook Park, Areum Durey, Kyung Hee Lee, Moon-Hyun Chung, Jin-Soo Lee
    Malaria Journal.2017;[Epub]     CrossRef
  • Respiratory Complications of Plasmodium vivax Malaria: Systematic Review and Meta-Analysis
    Hernando del Portillo, Fernando Val, Wuelton Marcelo Monteiro, Quique Bassat, Kim Machado, Lisiane Barbosa, Jorge Luis Salinas, André Machado Siqueira, Marcus Vinícius Guimarães Lacerda, Maria Graças Costa Alecrim
    The American Journal of Tropical Medicine and Hygiene.2017; 97(3): 733.     CrossRef
  • Extracorporeal Membrane Oxygenation in Dengue, Malaria, and Acute Chagas Disease
    Leonardo A. Salazar, Cornelis M. Schreuder, Jhonathan A. Eslava, Adriana S. Murcia, Mario J. Forero, Mauricio A. Orozco-Levi, Luis E. Echeverría, Anton io Figueredo
    ASAIO Journal.2017; 63(6): e71.     CrossRef
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    Spinello Antinori, Alberto Corona, Anna Lisa Ridolfo, Laura Galimberti, Davide Ricaboni, Laura Milazzo, Mario Corbellino
    Malaria Journal.2016;[Epub]     CrossRef
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Brief Communication

Discovery of Parvatrema duboisi and Parvatrema homoeotecnum (Digenea: Gymnophallidae) from Migratory Birds in Korea
Ok-Sik Chung, Hye-Jung Lee, Woon-Mok Sohn, Yun-Kyu Park, Jong-Yil Chai, Min Seo
Korean J Parasitol 2010;48(3):271-274.
Published online September 16, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.3.271

Adult worms of Parvatrema spp. (Digenea: Gymnophallidae) were found in the intestines of 2 species of migratory birds, i.e., a great knot, Calidris tenuirostris, and 2 Mongolian plovers, Charadrius mongolus, in the coastal area of Gunsan-si, Jeollabuk-do in October 2009. The recovered Parvatrema worms were 79 in total number and composed of 2 species. The worms from a great knot were 289 ?m in length with the oral and ventral sucker ratio of 2 : 1. They had a single vitellarium, and their intrauterine eggs were 25.0 × 17.5 ?m in size. These findings were compatible with P. duboisi (Dollfus, 1923) Bartoli, 1974 (syn. P. timondavidi Bartoli, 1963). The worms recovered from the Mongolian plovers were smaller in length than P. duboisi and had 2 vitellaria. The oral and ventral sucker ratio was 2.5 : 1, and the eggs were 17.5 × 8.8 ?m in size. These worms were assigned to be P. homoeotecnum James, 1964. This is the first report on the natural final hosts of Parvatrema spp. in Korea.

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    Kirill V. Galaktionov, Anna Gonchar, Daria Postanogova, Aleksei Miroliubov, Semen Yu. Bodrov
    International Journal for Parasitology.2024;[Epub]     CrossRef
  • Parvatrema duboisi (Digenea: Gymnophallidae) Life Cycle Stages in Manila Clams, Ruditapes philippinarum, from Aphae-do (Island), Shinan-gun, Korea
    Bong-Kwang Jung, Taehee Chang, Hyejoo Shin, Seungwan Ryoo, Sooji Hong, Jeonggyu Lee, Hyemi Song, Jaeeun Cho, Deok-Gyu Kim, Hojong Jun, Min-Jae Kim, Eun Jeong Won, Eun-Taek Han, Eun-Hee Shin, Jong-Yil Chai
    The Korean Journal of Parasitology.2021; 59(1): 83.     CrossRef
  • Molecular data reshape our understanding of the life cycles of three digeneans (Monorchiidae and Gymnophallidae) infecting the bivalve, Donax variabilis: it’s just a facultative host!
    Kristina M. Hill-Spanik, Claudia Sams, Vincent A. Connors, Tessa Bricker, Isaure de Buron
    Parasite.2021; 28: 34.     CrossRef
  • Morphological and Molecular Confirmation of Parvatrema duboisi Metacercariae in the Manila Clam Ruditapes philippinarum from Gochang-gun, Korea
    Taehee Chang, Bong-Kwang Jung, Hyejoo Shin, Sooji Hong, Jeonggyu Lee, Deok-Gyu Kim, Laddawan Patarwut, Woon-Mok Sohn, Jong-Yil Chai
    The Korean Journal of Parasitology.2020; 58(1): 87.     CrossRef
  • Infections with Digenetic Trematode Metacercariae in Freshwater Fishes from Two Visiting Sites of Migratory Birds in Gyeongsangnam-do, Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na
    The Korean Journal of Parasitology.2019; 57(3): 273.     CrossRef
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    Tommy L. F. Leung
    Biological Reviews.2017; 92(1): 410.     CrossRef
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    Seongjun Choe, Hyun Kim, Junsik Lim, Dongmin Lee, Hansol Park, Hyeong-Kyu Jeon, Heejong Kim, Youngjun Kim, Keeseon S. Eom
    The Korean Journal of Parasitology.2016; 54(3): 349.     CrossRef
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    Ahmet Özer, Sevilay Güneydağ
    Journal of the Marine Biological Association of the United Kingdom.2015; 95(8): 1591.     CrossRef
  • First report of Urosporidium sp., a haplosporidian hyperparasite infecting digenean trematode Parvatrema duboisi in Manila clam, Ruditapes philippinarum on the west coast of Korea
    Thanh Cuong Le, Hyun-Sil Kang, Hyun-Ki Hong, Kwang-Jae Park, Kwang-Sik Choi
    Journal of Invertebrate Pathology.2015; 130: 141.     CrossRef
  • Discovery ofMaritrema obstipum(Digenea: Microphallidae) from Migratory Birds in Korea
    Ok-Sik Chung, Woon-Mok Sohn, Jong-Yil Chai, Min Seo, Hye-Jung Lee
    The Korean Journal of Parasitology.2011; 49(4): 457.     CrossRef
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Original Articles

Extraintestinal Migration of Centrorhynchus sp. (Acanthocephala: Centrorhynchidae) in Experimentally Infected Rats
Chang-Jin Choi, Hye-Jung Lee, Jai-Hyang Go, Yun-Kyu Park, Jong-Yil Chai, Min Seo
Korean J Parasitol 2010;48(2):139-143.
Published online June 17, 2010
DOI: https://doi.org/10.3347/kjp.2010.48.2.139

Reptiles were known to serve as paratenic hosts for Centrorhynchus (Acanthocephala: Centrorhynchidae) in Korea, but the infection course in experimental animals was not elucidated yet. In this study, the tiger keelback snakes (Rhabdophis tigrinus) were collected and digested with artificial pepsin solution, and the larvae of Centrorhynchus were recovered from them. Then, the collected larvae were orally infected to rats for developmental observations. In rats, all the larvae were observed outside the intestine on day 3 post-infection (PI), including the mesentery and abdominal muscles. As for the development in rats, the ovary of Centrorhynchus sp. was observed at day 15 PI, and the cement glands were 3 in number. Based on the morphological characteristics, including the arrangement of proboscis hooks, these larvae proved to be a species of Centrorhynchus, and more studies were needed for species identification.

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    V.P. Nikishin, T.V. Davydenko, E.M. Skorobrekhova
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  • Helminth Fauna of Anatolian Rock Lizard Anatololacerta anatolica (Werner, 1902) from Western Anatolia, Türkiye
    E. B. Hastürk, S. Birlik, Ç. Ilgaz, A. G. Korkmaz, K. Candan, E. Yıldırım Caynak, Y. Kumlutaş
    Biology Bulletin.2025;[Epub]     CrossRef
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    Roberta da Rocha Braga, Deborah Praciano de Castro, Daniel Cassiano Lima, Cícero Ricardo de Oliveira, Robson Waldemar Ávila
    Ciência Animal Brasileira.2024;[Epub]     CrossRef
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    Roberta da Rocha Braga, Deborah Praciano de Castro, Daniel Cassiano Lima, Cícero Ricardo de Oliveira, Robson Waldemar Ávila
    Ciência Animal Brasileira.2024;[Epub]     CrossRef
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    Aditya Yudhana, Ratih Novita Praja, Ryanka Edila
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    Hanno Schmidt, Katharina Mauer, Manuel Glaser, Bahram Sayyaf Dezfuli, Sören Lukas Hellmann, Ana Lúcia Silva Gomes, Falk Butter, Rebecca C. Wade, Thomas Hankeln, Holger Herlyn
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    C. Caballero-Viñas, P. Sánchez-Nava
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A Nationwide Survey on the Prevalence of Intestinal Parasitic Infections in the Republic of Korea, 2004
Tong-Soo Kim, Shin-Hyeong Cho, Sun Huh, Yoon Kong, Woon-Mok Sohn, Seung-Sik Hwang, Jong-Yil Chai, Soon-Hyung Lee, Yun-Kyu Park, Dae-Kyu Oh, Jong-Koo Lee
Korean J Parasitol 2009;47(1):37-47.
Published online March 12, 2009
DOI: https://doi.org/10.3347/kjp.2009.47.1.37

National surveys on the prevalence of intestinal parasitic infections have been carried out every 5-7 years since 1971 in the Republic of Korea in order to establish control measures. The present nationwide survey was conducted from June to December 2004. The 10% population sampling data of Population and Housing Census by the Korean government in 2000 was used as the survey population. One sample was selected randomly from each of the 22,858 registered subjects, and a total of 20,541 people were ultimately included in this survey. Fecal examinations were performed by the cellophane thick smear and saturated brine flotation techniques. Pinworm infection was examined by cello-tape anal swab method. This survey also included a questionnaire study for a socioeconomic analysis. The total helminth egg positive rate was 3.7%, and the estimated total positive number among nationwide people was 1,780,000. The rates in urban and rural areas were 3.1% and 6.8%, respectively. As the total egg positive rate in the 6th survey in 1997 was 2.4%, the present survey showed that there was a considerable degree of increase in the prevalence rate of intestinal parasitic infections over the 7-year period following the 6th survey. The largest increases occurred in the egg positive rates of Clonorchis sinensis and heterophyids including Metagonimus yokogawai.

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Tegumental Ultrastructure of Adult Gynaecotyla squatarolae (Digenea: Microphallidae)
Do-Seon Lim, Ki-Ju Choi, Sang-Mee Guk, Jong-Yil Chai, Il-Yong Park, Yun-Kyu Park, Min Seo
Korean J Parasitol 2008;46(2):87-90.
Published online June 20, 2008
DOI: https://doi.org/10.3347/kjp.2008.46.2.87

Gynaecotyla squatarolae (Digenea: Microphallidae) adult flukes were recovered from experimental chicks at day 4-6 post-infection and their tegumental ultrastructure was observed with a scanning electron microscopy. They were pyriform in shape, and their anterior halves were concaved ventrally. The whole body surface was covered with tegumental spines, which were wide and 16-17 digitated between oral and ventral suckers. The density of spines and number of digits decreased posteriorly. The oral sucker was subterminal and the excretory pore was at the posterior end of the worm. Two ventral suckers were similar in appearance and protruded near midline of the worm. The genital atrium was dextral to the small ventral sucker. The dorsal surface was covered with tegumental spines, but the spines were sparser than on the ventral surface. On the middle portion of the dorsal surface, a small opening presumed to be the Laurer's canal was seen. From these findings, it has been confirmed that the adult G. squatarolae has unique characteristics in the surface ultrastructure.

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Case Report

A case of symptomatic splenic infarction in vivax malaria
Areum Kim, Yun-Kyu Park, Jin-Soo Lee, Moon-Hyun Chung, Eun Sil Kim
Korean J Parasitol 2007;45(1):55-58.
Published online March 20, 2007
DOI: https://doi.org/10.3347/kjp.2007.45.1.55

Splenic infarction is a rare complication in malaria cases, and is caused primarily by Plasmodium falciparum. Recently in South Korea, only P. vivax has prevailed since 1993. Although the probability that symptomatic splenic infarction may occur in vivax malaria cases is considered relatively high, there have never been any case reports describing the occurrence of symptomatic splenic infarction in cases of vivax malaria. A 34-year-old man presented with fever that had persisted for 5 days. P. vivax infection was verified using a peripheral blood smear, and chloroquine was utilized to treat the fever successfully. Six days later, the patient developed pain in the left upper abdomen, which was diagnosed as splenic infarction by computed tomography.

Citations

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    Jae Hyoung Im, Moon-Hyun Chung, Areum Durey, Hea Yoon Kwon, Jin-Soo Lee, Man-Jong Lee, Ji Hyeon Baek
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    JOSÉ FELIPE REOYO PASCUAL
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    Francesca F. Norman, Jorge Rojas-Marcos, José-Manuel Hermida-Donate, Begoña Monge-Maillo, Jose Antonio Perez-Molina, Rogelio López-Vélez
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    Ahmed H. Al-Salem
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    Philip G. McQueen
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    J. Kevin Baird
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    Eun Jung Jung, Eun Ju Choo, Tae Hyong Kim, Min Hyok Jeon, Eun Jeung Lee, Young Sin Cho, Ho Young Lee, Ji Yon Kim
    Infection and Chemotherapy.2008; 40(3): 179.     CrossRef
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    Philip G. McQueen, F. Ellis McKenzie, Rob J. De Boer
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Original Articles

A new endemic focus of Gymnophalloides seoi infection on Aphae Island, Shinan-gun, Jeollanam-do
Jae-Hwan Park, Sang-Mee Guk, Eun-Hee Shin, Hyo-Jin Kim, Jae-Lip Kim, Min Seo, Yun-Kyu Park, Jong-Yil Chai
Korean J Parasitol 2007;45(1):39-44.
Published online March 20, 2007
DOI: https://doi.org/10.3347/kjp.2007.45.1.39

A new endemic focus of Gymnophalloides seoi infection has been discovered on Aphae Island (Shinan-gun, Jeollanam-do), Republic of Korea. This area, which is referred to as Bokyong-ri, is a small seashore village located in the northern portion of the island. Fecal samples were collected from a total of 57 residents and examined by the Kato-Katz and formalin-ether sedimentation techniques. Helminth eggs were detected in 37 samples (64.9%); 33 samples were positive for G. seoi eggs (57.9%), 4 for Pygidiopsis summa (7.0%), 13 for other heterophyids (22.8%), 1 for Clonorchis sinensis (1.7%), and 1 for Trichuris trichiura (1.7%). Women (70.4%) revealed higher rates of G. seoi infection than did men (46.7%), and individuals older than 50 years of age also evidenced higher rates of G. seoi infection than in other age groups (P< 0.05). In worm collection from 13 G. seoi egg positive cases, G. seoi (total 86,558 specimens), Heterophyes nocens (278), Stictodora sp. (10), Heterophyopsis continua (3), P. summa (3), and unidentified flukes (42) were collected. Oysters, the source of G. seoi infection, were collected from an area proximal to the village and 50 were examined for metacercariae; 47 (94%) were found infected and the observed metacercarial density was 9.5 ± 8.9 per oyster. The results of this study indicate that Bokyong-ri is a new endemic area of G. seoi infection, with high rates of infection in humans and oysters.

Citations

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  • Survey of Gymnophalloides seoi Metacercariae in Natural and Cultured Oysters from Several Western Coastal Areas, Korea
    Taehee Chang, Bong-Kwang Jung, Hyemi Song, Jaeeun Cho, Sooji Hong, Keon-Hoon Lee, Eui-Hyug Hoang, Jisu Kang, Jini Lim, Hana Lee, Jong-Yil Chai
    The Korean Journal of Parasitology.2019; 57(6): 705.     CrossRef
  • Pygidiopsis summa (Digenea: Heterophyidae): Status of Metacercarial Infection in Mullets from Coastal Areas in the Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Won-Ja Lee, Mi-Yeoun Park, Soon-Won Lee, Seung-Bong Choi, Beom-Nyung Huh, Won-Seok Seok
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    Gab-Man Park
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    Jong-Yil Chai
    Journal of the Korean Medical Association.2007; 50(11): 946.     CrossRef
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A new endemic focus of Heterophyes nocens and other heterophyid infections in a coastal area of Gangjin-gun, Jeollanam-do
Jae-Hwan Park, Jae-Lip Kim, Eun-Hee Shin, Sang-Mee Guk, Yun-Kyu Park, Jong-Yil Chai
Korean J Parasitol 2007;45(1):33-38.
Published online March 20, 2007
DOI: https://doi.org/10.3347/kjp.2007.45.1.33

To know the prevalence of heterophyid trematodes among inhabitants of a southern coastal village, i.e., Sacho-ri, Gangjin-gun, Jeollanam-do (Province), 82 stool samples were examined on helminth eggs and protozoan cysts using Kato-Katz and formalin-ether sedimentation techniques. Total 33 people (40.2%) were positive for trematodes (Heterophyes nocens; 15 people, Pygidiopsis summa; 3, Metagonimus sp.; 4, Clonorchis sinensis; 7, Gymnophalloides seoi; 6) and/or protozoa (Entamoeba coli; 3). Among intestinal trematode egg positive cases, 17 were treated with praziquantel and their whole diarrheic stools were collected after purgation. Adult flukes of H. nocens (number of specimens = 1,294), P. summa (386), Stellantchasmus falcatus (5), Stictodora lari (4), and Heterophyopsis continua (1) were collected using a stereomicroscope. To know the source of human H. nocens infections in this village, metacercarial infections in mullets (10) were examined and most H. nocens metacercariae (101/105, 96.2%) were found in the trunk portion. From above results, the surveyed coastal village has been newly known as an endemic focus of human H. nocens infection and consuming raw mullets was the presumable source of human heterophyid infections.

Citations

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Complement-mediated tail degradation of Neodiplostomum seoulense cercariae
Yun-Kyu Park, Myung-Ki Hwang, Yun-Jung Jung
Korean J Parasitol 2006;44(2):127-131.
Published online June 20, 2006
DOI: https://doi.org/10.3347/kjp.2006.44.2.127

The furcocercus cercariae of Neodiplostomum seoulense (Digenea: Neodiplostomidae) penetrate the skins of tadpoles and shed their tails. The speculated mechanism of this tail loss was physical efforts required to produce a vigorous zigzag motion during skin penetration; no other mechanism has been proposed. We examined the relationship between the host serum and cercarial tail loss. Cercariae of N. seoulense were collected from experimentally infected Segmentina hemisphaerula, and lots of 300 cercariae were cultured in medium 199 contained several types of sera. Cercarial tail degradation was induced in all media, but all the cercariae cultured except those cultured in media containing fetal bovine serum (FBS) died within 48 hr. After 72 hr cultivation in media containing FBS, cercarial tail degradation was induced in 67.0%; in continuous cultivation 13.3% of larvae survived for 7 days. Tail degradation did not occur in the absence of serum and when serum was heat inactivated at 56℃ for 30 min. The addition of 20 mM ethylenediaminetetraacetic acid (EDTA) blocked cercarial tail degradation completely. Moreover, the addition of 20 mM MgCl2 restored tail degradation blocked by EDTA. These results suggest that the alternative complement pathway is related with the N. seoulense cercarial tail degradation induced by serum.

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Brief Communication

A new method for concentration of proteins in the calcareous corpuscles separated from the spargana of Spirometra erinacei
Yun-Kyu Park, Jae-Hwan Park, Sang-Mee Guk, Eun-Hee Shin, Jong-Yil Chai
Korean J Parasitol 2005;43(3):119-122.
Published online September 20, 2005
DOI: https://doi.org/10.3347/kjp.2005.43.3.119

Calcareous corpuscles are a characteristic structure found in larval and adult stage cestodes. These corpuscles are known to contain several protein components and to possess protein-binding activity. However, the proteins bound to calcareous corpuscles in situ have not been studied. The present study was undertaken to identify the proteins on calcareous corpuscles. Calcareous corpuscles were purified from the plerocercoids (= spargana) of Spirometra erinacei, and serially dissolved using 0.1 M sulfamic acid solution. Collected supernatants were examined by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) and silver staining. The results showed that only the fraction remaining after the 19th dissolved fraction contained proteins. A total of 20 protein molecules were detected in gel, with major bands at 56, 53, 46, 40, 35, 29, 28, 24.5, 21, 19, 16, 13, 10 and 8 kDa. In particular, the proteins corresponding to the 21 and 16 kDa bands were most abundant. Our results demonstrated for the first time the protein contents of the calcareous corpuscles of spargana. Further studies on the functions of these proteins are required.

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    Jae-Hwan Kim, Young Ju Kim, Woon-Mok Sohn, Young Mee Bae, Sung-Tae Hong, Min-Ho Choi
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Original Article

Parasitic infections in HIV-infected patients who visited Seoul National University Hospital during the period 1995-2003
Sang-Mee Guk, Min Seo, Yun-Kyu Park, Myoung-Don Oh, Kang-Won Choe, Jae-Lip Kim, Min-Ho Choi, Sung-Tae Hong, Jong-Yil Chai
Korean J Parasitol 2005;43(1):1-5.
Published online March 20, 2005
DOI: https://doi.org/10.3347/kjp.2005.43.1.1

The prevalence of parasitic infections was investigated in human immunodeficiency virus (HIV)-infected patients (n = 105) who visited Seoul National University Hospital, Seoul, Korea, during the period from 1995 to 2003. Fecal samples were collected from 67 patients for intestinal parasite examinations, and sputum or bronchoalveolar lavage samples from 60 patients for examination of Pneumocystis carinii. Both samples were obtained from 22 patients. Thirty-three (31.4%) of the 105 were found to have parasitic infections; Cryptosporidium parvum (10.5%; 7/67), Isospora belli (7.5%; 5/67), Clonorchis sinensis (3.0%; 2/67), Giardia lamblia (1.5%; 1/67), Gymnophalloides seoi (1.5%; 1/67), and Pneumocystis carinii (28.3%; 17/60). The hospital records of the 11 intestinal parasite-infected patients showed that all suffered from diarrhea. This study shows that parasitic infections are important clinical complications in HIV-infected patients in the Republic of Korea.

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Brief Communication

Corbicula fluminea (Bivalvia: Corbiculidae): a possible second molluscan intermediate host of Echinostoma cinetorchis (Trematoda: Echinostomatidae) in Korea
Pyung-Rim Chung, Younghun Jung, Yun-Kyu Park, Myung-Gi Hwang, Chin-Thack Soh
Korean J Parasitol 2001;39(4):329-332.
Published online December 31, 2001
DOI: https://doi.org/10.3347/kjp.2001.39.4.329

More than 1,500 clams of Corbicula fluminea, the most favorable food source of freshwater bivalves in Korea, were collected from 5 localities to examine cercarial and metacercarial infection with Echinostoma cinetorchis. Although 3 clams infected with suspicious E. cinetorchis metacercariae out of 200 specimens collected at Kangjin, Chollanam-do were detected, no cercarial and metacercarial infections with E. cinetorchis were observed in field-collected Corbicula specimens. In the susceptibility experiments with laboratory-reared clams, those infected with miracidia of E. cinetorchis did not release their cercariae up to 60 days after infection. To confirm the identity of second intermediate host of E. cinetorchis experimentally, a total of 30 clams were exposed to the cercariae from Segmentina hemisphaerula that had been infected with miracidia of E. cinetorchis. The clams were susceptible to cercariae of E. cinetorchis with an infection rate of 93.3%. Metacercariae from clams taken more than 7 days after cercarial exposure were fed to rats (S/D strain), and adult worms of E. cinetorchis, characterized by 37-38 collar spines on the head crown, were recovered from the ileocecal regions. This is the first report of C. fluminea as a possible second intermediate host of E. cinetorchis.

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  • Lower parasite pressure in invasive freshwater bivalves than in sympatric native Unionidae mussels in southern European lakes
    Binglin Deng, Nicoletta Riccardi, Maria Urbańska, Timo J. Marjomäki, Wojciech Andrzejewski, Jouni Taskinen
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    Yun-Kyu Park, Myung-Ki Hwang, Pyung-Rim Chung
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  • Host Specificity of Pisidium coreanum (Bivalvia: Sphaeriidae) to Larval Infection with a Human Intestinal Fluke Echinostoma cinetorchis (Trematoda: Echinostomatidae) in Korea
    Y. K. Park, C. T. Soh, G. M. Park, M. K. Hwang, P. R. Chung
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Original Articles

Austropeplea ollula (Pulmonata: Lymnaeidae): A new molluscan intermediate host of a human intestinal fluke, Echinostoma cinetorchis (Trematoda: Echinostomatidae) in Korea
Pyung-Rim Chung, Younghun Jung, Yun-Kyu Park, Myung-Ki Hwang
Korean J Parasitol 2001;39(3):247-253.
Published online September 30, 2001
DOI: https://doi.org/10.3347/kjp.2001.39.3.247

Three freshwater snail species of the family Lymnaeidae have been reported from Korea, Radix auricularia coreana, Austropeplea ollula and Fossaria truncatula. Out of 3 lymnaeid snail species, A. ollula was naturally infected with the Echinostoma cinetorchis cercariae (infection rate = 0.7%). In the experiments with the laboratory-bred snails, F. truncatula as well as A. ollula was also susceptible to the E. cinetorchis miracidia with infection rates of 25% and 40%, respectively. All of three lymnaeid snail species exposed to the E. cinetorchis cercariae were infected with the E. cinetorchis metacercariae. It is evident that A. ollula acts as the first molluscan intermediate host of E. cinetorchis in Korea, and F. truncatula may be a possible candidate for the first intermediate host of this intestinal fluke. Also, three lymnaeid snail species targeted were experimentally infected with E. cinetorchis metacercariae.

Citations

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  • The Nuclear Ribosomal Transcription Units of Two Echinostomes and Their Taxonomic Implications for the Family Echinostomatidae
    Yu Cao, Ye Li, Zhong-Yan Gao, Bo-Tao Jiang
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    Preeyaporn Butboonchoo, Chalobol Wongsawad, Pheravut Wongsawad, Jong-Yil Chai
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    Louise Puslednik, Winston F. Ponder, Mark Dowton, Andrew R. Davis
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Persistent endemicity of Gymnophalloides seoi infection in a southwestern coastal village of Korea with special reference to its egg laying capacity in the human host
Jong-Yil Chai, Geun Chan Lee, Yun-Kyu Park, Eun-Taek Han, Min Seo, Jin Kim, Sang-Mee Guk, Eun-Hee Shin, Min-Ho Choi, Soon-Hyung Lee
Korean J Parasitol 2000;38(2):51-57.
Published online June 30, 2000
DOI: https://doi.org/10.3347/kjp.2000.38.2.51

Follow-up studies have been conducted every three years on the endemicity of Gymnophalloides seoi infection in a small coastal village of Chollanam-do (Province), Korea, since it was first known as an endemic area in 1994. Special attention was given to its egg laying capacity in the human host. In fecal examinations, the overall helminth egg and/or cyst positive rate was 78.7% (74/94) in 1997 and 76.6% (82/107) in 2000. Among them G. seoi eggs showed the highest rate; 71.3% (67/94) in 1997 and 72.0% (77/107) in 2000. The average number of eggs per gram of feces (EPG) was 1,015 in 1997, while a reduced rate of 353 was observed in 2000. In 1997, total of 320,677 adult flukes of G. seoi (av. 10,344/person, 94-69,125 in range) were collected from the diarrheic stools of 31 treated patients. The EPG/worm obtained from 21 cases ranged from 0.04 to 0.77 (av. 0.23), suggesting density-dependent constraints on the worm fecundity. The relationship between the worm burden (X) and EPG/worm (Y) can be expressed as Y=0.42 ·e-1.2χ (r=0.49). The results showed that G. seoi infection is persistently endemic in this village.

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    The Korean Journal of Parasitology.2010; 48(1): 81.     CrossRef
  • Intestinal Helminth Infections in Feral Cats and a Raccoon Dog on Aphaedo Island, Shinan-gun, with a Special Note on Gymnophalloides seoi Infection in Cats
    Eun-Hee Shin, Jae-Hwan Park, Sang-Mee Guk, Jae-Lip Kim, Jong-Yil Chai
    The Korean Journal of Parasitology.2009; 47(2): 189.     CrossRef
  • Foodborne Intestinal Flukes in Southeast Asia
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    The Korean Journal of Parasitology.2009; 47(Suppl): S69.     CrossRef
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    The Korean Journal of Parasitology.2007; 45(3): 205.     CrossRef
  • A new endemic focus of Heterophyes nocens and other heterophyid infections in a coastal area of Gangjin-gun, Jeollanam-do
    Jae-Hwan Park, Jae-Lip Kim, Eun-Hee Shin, Sang-Mee Guk, Yun-Kyu Park, Jong-Yil Chai
    The Korean Journal of Parasitology.2007; 45(1): 33.     CrossRef
  • A new endemic focus of Gymnophalloides seoi infection on Aphae Island, Shinan-gun, Jeollanam-do
    Jae-Hwan Park, Sang-Mee Guk, Eun-Hee Shin, Hyo-Jin Kim, Jae-Lip Kim, Min Seo, Yun-Kyu Park, Jong-Yil Chai
    The Korean Journal of Parasitology.2007; 45(1): 39.     CrossRef
  • Collection of Clonorchis sinensis adult worms from infected humans after praziquantel treatment
    Chenghua Shen, Jae-hwan Kim, Jeong-Keun Lee, Young Mee Bae, Min-Ho Choi, Jin-Kyoung Oh, Min Kyung Lim, Hai-Rim Shin, Sung-Tae Hong
    The Korean Journal of Parasitology.2007; 45(2): 149.     CrossRef
  • Prevalence of Gymnophalloides seoi infection in coastal villages of Haenam-gun and Yeongam-gun, Republic of Korea
    Sang-Mee Guk, Jae-Hwan Park, Eun-Hee Shin, Jae-Lip Kim, Aifen Lin, Jong-Yil Chai
    The Korean Journal of Parasitology.2006; 44(1): 1.     CrossRef
  • A case of colonic lymphoid tissue invasion by Gymnophalloides seoi in a Korean man
    Min Seo, Hokyung Chun, Geunghwan Ahn, Kee-Taek Jang, Sang-Mee Guk, Jong-Yil Chai
    The Korean Journal of Parasitology.2006; 44(1): 87.     CrossRef
  • Gymnophalloides seoi: a new human intestinal trematode
    Jong-Yil Chai, Min-Ho Choi, Jae-Ran Yu, Soon-Hyung Lee
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    Parasitology International.2002; 51(2): 129.     CrossRef
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    Journal of Parasitology.2002; 88(3): 627.     CrossRef
  • A review of Gymnophalloides seoi (Digenea: Gymnophallidae) and human infections in the Republic of Korea
    Soon-Hyung Lee, Jong-Yil Chai
    The Korean Journal of Parasitology.2001; 39(2): 85.     CrossRef
  • A nationwide survey of the prevalence of human Gymnophalloides seoi infection on western and southern coastal islands in the Republic of Korea
    Jong-Yil Chai, Jae-Hwan Park, Eun-Taek Han, Eun-Hee Shin, Jae-Lip Kim, Kwang-Seon Hong, Han-Jong Rim, Soon-Hyung Lee
    The Korean Journal of Parasitology.2001; 39(1): 23.     CrossRef
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Brief Communication

High endemicity of Metagonimus yokogawai infection among residents of Samchok-shi, Kangwon-do
Jong-Yil Chai, Eun-Taek Han, Yun-Kyu Park, Sang-Mee Guk, Jae-Lip Kim, Soon-Hyung Lee
Korean J Parasitol 2000;38(1):33-36.
Published online March 31, 2000
DOI: https://doi.org/10.3347/kjp.2000.38.1.33

A small-scale epidemiological survey was undertaken during 1997-1998 on the residents along the Osib-chon (Stream), Samchok-shi (City), Kangwon-do (Province), to evaluate the status of Metagonimus yokogawai infection. A total of 165 fecal samples was collected and examined by cellophane thick smear and formalin-ether sedimentation techniques. The egg positive rate of M. yokogawai was 29.7%, showing a remarkable difference between males (46.6%) and females (16.3%). To obtain the adult flukes of M. yokogawai, 11 egg positive persons were treated with praziquantel and purged with magnesium sulfate. A total of 242,119 adult flukes (average 22,010 per person, 367-119,650 in range) was collected from diarrheic stools, all of which were identified as M. yokogawai. The results show that M. yokogawai is still highly endemic in this area.

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    The Korean Journal of Parasitology.2018; 56(4): 351.     CrossRef
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    The Korean Journal of Parasitology.2009; 47(Suppl): S69.     CrossRef
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    The Korean Journal of Parasitology.2009; 47(1): 37.     CrossRef
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  • Decrease of Metagonimus yokogawai Endemicity along the Tamjin River Basin
    Jin-Ju Lee, Hyo-Jin Kim, Min-Jae Kim, Jo Woon Yi Lee, Bong-Kwang Jung, Ji-Youn Lee, Eun-Hee Shin, Jae-Lip Kim, Jong-Yil Chai
    The Korean Journal of Parasitology.2008; 46(4): 289.     CrossRef
  • SUSCEPTIBILITY OF INBRED MOUSE STRAINS TO INFECTION WITH THREE SPECIES OF METAGONIMUS PREVALENT IN THE REPUBLIC OF KOREA
    Sang-Mee Guk, Jin-Young Park, Min Seo, Eun-Taek Han, Jae-Lip Kim, Jong-Yil Chai
    Journal of Parasitology.2005; 91(1): 12.     CrossRef
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  • Epidemiological study of clonorchiasis and metagonimiasis along the Geum-gang (River) in Okcheon-gun (County), Korea
    Gye-Sung Lee, In-Sung Cho, Young-Ha Lee, Hyung-Jun Noh, Dae-Whan Shin, Sok-Goo Lee, Tae-Yong Lee
    The Korean Journal of Parasitology.2002; 40(1): 9.     CrossRef
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Case Report

A toxoplasmic uveitis case of a 60-year-old male in Korea
Min-Ho Kim, Yeun-Kyoung Choi, Yun-Kyu Park, Ho-Woo Nam
Korean J Parasitol 2000;38(1):29-31.
Published online March 31, 2000
DOI: https://doi.org/10.3347/kjp.2000.38.1.29

A toxoplasmic uveitis case was reported on the focus of impairment of pathological findings and serological antibody titers after chemotherapy. A chief complaint of a 60-year-old male was a decreased and blurred vision in his right eye for 2 weeks after experiencing tremendous stress and fatigue. A steroid therapy for 3 weeks was not effective and the retinal lesion became necrotic. Anti-Toxoplasma gondii antibody titer was checked to be a strong positive by both ELISA and indirect latex agglutination assay (ILA). He was treated with Fansidar F for 8 weeks. His vision improved as the necrotic lesion healed by scarring, but the antibody titers still remained very high without any signs of negative conversion. It is suggested to be a recurrent case of the past asymptomatic infection by presumed immune suppression caused by excessive stress.

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  • Seroprevalence of Toxoplasma gondii assayed using Rapid Diagnostic Tests among Residents in Three Counties Adjacent to The Demilitarized Zone, Korea
    Jeehi Jung, Jinyoung Lee, Yoon Kyung Chang, Seong Kyu Ahn, Seo Hye Park, Sung-Jong Hong, Jihoo Lee, Chom-Kyu Chong, Hye-Jin Ahn, Ho-Woo Nam, Tong-Soo Kim, Dongjae Kim
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  • Clusters of Toxoplasmosis in Ganghwa-gun, Cheorwon-gun, and Goseong-gun, Korea
    Jihye Yu, Woojin Kim, Yoon Kyung Chang, Tong-Soo Kim, Sung-Jong Hong, Hye-Jin Ahn, Ho-Woo Nam, Dongjae Kim
    The Korean Journal of Parasitology.2021; 59(3): 251.     CrossRef
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    Woojin Kim, Yoon Kyung Chang, Tong-Soo Kim, Sung-Jong Hong, Hye-Jin Ahn, Ho-Woo Nam, Dongjae Kim
    The Korean Journal of Parasitology.2020; 58(5): 493.     CrossRef
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    Yeong Hoon Kim, Ji hoo Lee, Seong kyu Ahn, Tong-Soo Kim, Sung-Jong Hong, Chom-Kyu Chong, Hye-Jin Ahn, Ho-Woo Nam
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    Yeong Hoon Kim, Jihoo Lee, Young-Eun Kim, Seongkyu Ahn, Tong-Soo Kim, Sung-Jong Hong, Chom-Kyu Chong, Hye-Jin Ahn, Ho-Woo Nam
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  • Detection of Ocular Toxoplasma gondii Infection in Chronic Irregular Recurrent Uveitis by PCR
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    Young-Hoon Park, Jae-Hyung Han, Ho-Woo Nam
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  • Laboratory passage and characterization of an isolate of Toxoplasma gondii from an ocular patient in Korea
    Jong-Yil Chai, Aifen Lin, Eun-Hee Shin, Myoung-Don Oh, Eun-Taek Han, Ho-Woo Nam, Soon-Hyung Lee
    The Korean Journal of Parasitology.2003; 41(3): 147.     CrossRef
  • Molecular cloning of ribosomal P protein in Toxoplasma gondii and the availability to detect antibody against recombinant protein in toxoplasmosis patients
    Hye-Jin Ahn, Sera Kim, Ho-Woo Nam
    The Korean Journal of Parasitology.2003; 41(2): 89.     CrossRef
  • Protease Activity and Host Cell Binding of the 42-kDa Rhoptry Protein from Toxoplasma gondii after Secretion
    Hye-Jin Ahn, Kyoung-Ju Song, Eui-Sun Son, Jong-Chul Shin, Ho-Woo Nam
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  • Detection and characterization of excretory/secretory proteins from Toxoplasma gondii by monoclonal antibodies
    Eui-Sun Son, Ho-Woo Nam
    The Korean Journal of Parasitology.2001; 39(1): 49.     CrossRef
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Original Articles

Serum from mouse orally ingested with tissue cyst forming strain (Me49) of Toxoplasma gondii was assayed by Western blot and immunofluorescene assay (IFA) to establish early responses in antigenicity of the parasite in mouse model of foodborne toxoplasmosis. Sera were collected weekly to blot the RH antigen transferred onto nitrocellulose paper after being separated by 12% SDS-PAGE. With the second week serum, 34 kDa protein (p34) was detected uniquely, and all antigens of T. gondii were detected with the sera from 3 or 4 weeks. p34 was not a member of the major surface membrane proteins and confirmed to be localized in the rhoptry by IFA. It was secreted into parasitophorous vacuolar membrane (PVM) during the entry into host cells. When applied to the human sera of which the ELISA absorbance was in negative range, 10.3% of sera detected p34, while all the ELISA positive sera detected the band. It has diagnostic usefulness of presumed T. gondii infection. We suggest the name of the p34 protein as ROP9.

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  • A systematic review of Toxoplasma gondii antigens to find the best vaccine candidates for immunization
    Fatemeh Rezaei, Shahabeddin Sarvi, Mahdi Sharif, Seyed Hossein Hejazi, Abdol sattar Pagheh, Sargis A. Aghayan, Ahmad Daryani
    Microbial Pathogenesis.2019; 126: 172.     CrossRef
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    Ahmad Daryani, Mehdi Sharif, Hamed Kalani, Alireza Rafiei, Farzad Kalani, Ehsan Ahmadpour
    Jundishapur Journal of Microbiology.2014;[Epub]     CrossRef
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    John C. Boothroyd, Jean-Francois Dubremetz
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    Hye-Seong Mun, Kazumi Norose, Fumie Aosai, Mei Chen, Akihiko Yano
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Is Pneumocystis carinii vertically transmitted to neonatal rats?
Sung-Tae Hong, Yun-Kyu Park, Jin Kim, Dug-Ha Kim, Chong-Ku Yun
Korean J Parasitol 1999;37(3):149-156.
Published online September 30, 1999
DOI: https://doi.org/10.3347/kjp.1999.37.3.149

Pneumocystis carinii is a pulmonary pathogen of immunocompromised humans or other mammals. Its infection results from activation of organisms involved in latent infection or from new infection through the air. Almost all children are known to be infected within 2 to 4 years of birth, though prenatal transplacental transmission has not yet been demonstrated. In this study we observed experimental P. carinii infection in neonatal rats, thus investigating the possibility of transplacental vertical transmission by Diff-Quik staining of the lung impression smears and in-situ hybridization for lung sections. The positive rate of P. carinii infection in immunosuppressed maternal rats was 100%, but that in normal maternal rats was 0%. Cystic forms of P. carinii were observed in three of six 1-week old neonatal rats born of heavily infected mothers, but none of them was positive by in-situ hybridization. Five weeks after birth, cystic forms were detected in four neonatal rats. In the lobes of the lungs, no predilection site of P. carinii was recognized. Counts of cystic forms on smears and the reactivity of in-situ hybridization in the lungs of neonatal rats were significantly lower than in maternal rats. The present findings suggest that P. carinii is rarely transmitted through the placenta and proliferates less successfully in the lungs of neonatal rats than in mothers.

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    Joseph H. Skalski, Theodore J. Kottom, Andrew H. Limper, Carol Munro
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    Crystal R. Icenhour, Sandra L. Rebholz, Margaret S. Collins, Melanie T. Cushion
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    Jae-Ran Yu, Jae-Kyong Pyon, Min Seo, Byung-Suk Jung, Sang Rock Cho, Soon-Hyung Lee, Sung-Tae Hong
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  • Early Acquisition of Pneumocystis carinii in Neonatal Rats using Targeted PCR and Oral Swabs
    CRYSTAL R. ICENHOUR, SANDRA L. REBHOLZ, MARGARET S. COLLINS, MELANIE T. CUSHION
    Journal of Eukaryotic Microbiology.2001;[Epub]     CrossRef
  • Pneumocystis infections: the iceberg?
    E. Dei-Cas
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Growth and development of Gymnophalloides seoi in immunocompetent and immunosuppressed C3H/HeN mice
Jong-Yil Chai, Won-Jae Chung, Jina Kook, Min Seo, Yun-Kyu Park, Sang-Mee Guk, Min-Ho Choi, Soon-Hyung Lee
Korean J Parasitol 1999;37(1):21-26.
Published online March 31, 1999
DOI: https://doi.org/10.3347/kjp.1999.37.1.21

The growth and development of Gymnophalloides seoi were studied in C3H/HeN mice and effects of immunosuppression of the host on the worm development were observed. Two hundred metacercariae of G. seoi were orally administered to each mouse, and worms were recovered on days 1, 3, 5, 7, 14 and 21 post-infection (PI). The worm recovery rate was significantly higher in immunosuppressed (ImSP) mice than in immunocompetent (ImCT) mice except on days 1 and 3 PI. The worms attained sexual maturity by day 3 PI with eggs in the uterus, and worm dimensions and the number of uterine eggs continuously increased until day 14 PI in ImSP mice. Worms recovered from ImSP mice were significantly larger in size than those from ImCT mice on days 1 and 3 PI, and the number of uterine eggs was significantly larger in ImSP mice on days 5 and 7 PI. Genital organs such as the ovary, testes, and vitellaria, that were already developed in the metacercarial stage, grew a little in size until day 14 PI. The results show that the C3H/HeN mouse is, though not excellent, a suitable laboratory host for G. seoi.

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  • Increased Intestinal Epithelial Cell Turnover and Intestinal Motility in Gymnophalloides seoi-Infected C57BL/6 Mice
    Sang Hyub Lee, Bong-Kwang Jung, Jae-Hwan Park, Eun-Hee Shin, Jong-Yil Chai
    The Korean Journal of Parasitology.2014; 52(3): 273.     CrossRef
  • Foodborne Intestinal Flukes in Southeast Asia
    Jong-Yil Chai, Eun-Hee Shin, Soon-Hyung Lee, Han-Jong Rim
    The Korean Journal of Parasitology.2009; 47(Suppl): S69.     CrossRef
  • Gymnophalloides seoi: a new human intestinal trematode
    Jong-Yil Chai, Min-Ho Choi, Jae-Ran Yu, Soon-Hyung Lee
    Trends in Parasitology.2003; 19(3): 109.     CrossRef
  • Food-borne intestinal trematode infections in the Republic of Korea
    Jong-Yil Chai, Soon-Hyung Lee
    Parasitology International.2002; 51(2): 129.     CrossRef
  • A review of Gymnophalloides seoi (Digenea: Gymnophallidae) and human infections in the Republic of Korea
    Soon-Hyung Lee, Jong-Yil Chai
    The Korean Journal of Parasitology.2001; 39(2): 85.     CrossRef
  • Intestinal histopathology and in situ postures of Gymnophalloides seoi in experimentally infected mice
    Jong-Yil Chai, Hong-Soon Lee, Sung-Jong Hong, Jae Hyung Yoo, Sang-Mee Guk, Min Seo, Min-Ho Choi, Soon-Hyung Lee
    The Korean Journal of Parasitology.2001; 39(1): 31.     CrossRef
  • 9,112 View
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Toxoplasma gondii antibody titers in sera of children admitted to the Seoul National University Children's Hospital
Jina Kook, Hong-Jin Lee, Beyong Il Kim, Chong-Ku Yun, Sang-Mee Guk, Min Seo, Yun-Kyu Park, Sung-Tae Hong, Jong-Yil Chai
Korean J Parasitol 1999;37(1):27-32.
Published online March 20, 1999
DOI: https://doi.org/10.3347/kjp.1999.37.1.27

A total of 542 children under 10 years of age, admitted to the Seoul National University Children's Hospital, was examined for antibody titers of Toxoplasma gondii using indirect latex agglutination (ILA) test. Among them, 7.7% showed positive titers higher than 1:32, without significant difference between males (7.3%) and females (8.5%). The seropositive rate increased with age although the statistical significance was negligible (0.05<P<0.1). By residential areas, the prevalence appeared higher among children from southern provinces (Kyongsang-do and Cholla-do) than those from other areas, but the statistical significance was also very low (0.05<P<0.1). When the seropositive cases were analyzed by coincidental diseases, the prevalence was significantly higher in patients with congenital diseases than in patients with non-congenital diseases (P<0.05). The results showed that the seropositive rate of toxoplasmosis in children examined was not high compared with other endemic countries. Some correlations are suggested between toxoplasmosis and congenital anomalies in Korea.

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    Farah Bokharaei-Salim, Khadijeh Khanaliha, Shirin Sayyahfar, Mohsen Sadeghi, Ahmad Tavakoli, Borna Salemi
    Archives of Pediatric Infectious Diseases.2022;[Epub]     CrossRef
  • Molecular Detection of Toxoplasma Gondii in Haemaphysalis Ticks in Korea
    Ju Yeong Kim, You Shine Kwak, In-Yong Lee, Tai-Soon Yong
    The Korean Journal of Parasitology.2020; 58(3): 327.     CrossRef
  • Seroprevalence of Toxoplasma gondii among a group of Egyptian patients with type I diabetes mellitus
    Hala M. Khattab, Safeya O. El Bassiouni, Manal H. Abuelela, Dalia O. Abd Elsalam
    Bulletin of the National Research Centre.2019;[Epub]     CrossRef
  • Seroprevalence of anti-Toxoplasma IgG and IgM among individuals who were referred to medical laboratories in Mazandaran province, northern Iran
    Mehdi Sharif, Ahmad Daryani, Zahra Ebrahimnejad, Shirzad Gholami, Ehsan Ahmadpour, Samaneh Borhani, Narges Lamsechi
    Journal of Infection and Public Health.2016; 9(1): 75.     CrossRef
  • Toxoplasma gondii infection: seroprevalence and associated risk factors among primary schoolchildren in Lagos City, Southern Nigeria
    Vincent Pam Gyang, Olaoluwa Pheabian Akinwale, Yueh-Lun Lee, Ting-Wu Chuang, Akwaowo Orok, Olusola Ajibaye, Chien-Wei Liao, Po-Ching Cheng, Chia-Mei Chou, Ying-Chieh Huang, Kuo-Hua Fan, Chia-Kwung Fan
    Revista da Sociedade Brasileira de Medicina Tropical.2015; 48(1): 56.     CrossRef
  • Prevalence of toxoplasmosis in France in 1998: Is there a difference between men and women? At what age do children become infected?
    H. Bellali, H. Pelloux, I. Villena, H. Fricker-Hidalgo, Y. Le Strat, V. Goulet
    Revue d'Épidémiologie et de Santé Publique.2013; 61(4): 311.     CrossRef
  • Toxoplasma gondii infection: relationship between seroprevalence and risk factors among primary schoolchildren in the capital areas of Democratic Republic of São Tomé and Príncipe, West Africa
    Chia-Kwung Fan, Lin-Wen Lee, Chien-Wei Liao, Ying-Chieh Huang, Yueh-Lun Lee, Yu-Tai Chang, Ângela dos Santos Ramos José da Costa, Vilfrido Gil, Li-Hsing Chi, Takeshi Nara, Akiko Tsubouchi, Olaoluwa Pheabian Akinwale
    Parasites & Vectors.2012;[Epub]     CrossRef
  • Serologic Survey of Toxoplasmosis in Seoul and Jeju-do, and a Brief Review of Its Seroprevalence in Korea
    Hyemi Lim, Sang-Eun Lee, Bong-Kwang Jung, Min-Ki Kim, Mi Youn Lee, Ho-Woo Nam, Jong-Gyun Shin, Cheong-Ha Yun, Han-Ik Cho, Eun-Hee Shin, Jong-Yil Chai
    The Korean Journal of Parasitology.2012; 50(4): 287.     CrossRef
  • Seroprevalence and Incidence of Toxoplasma gondii among Apparently Healthy and Visually or Hearing Disabled Children in Taiz City, Yemen
    Madha Mohammed Sheet Saleh, Adam Hezam AL-Shamiri, Abeer Ahmed Qaed
    The Korean Journal of Parasitology.2010; 48(1): 71.     CrossRef
  • Seroprevalence ofToxoplasmagondiiinfection among children in Swaziland, southern Africa
    C. W. Liao, Y. L. Lee, H. Sukati, P. D'lamini, Y. C. Huang, C. J. Chiu, Y. H. Liu, C. M. Chou, W. T. Chiu, W. Y. Du, C. C. Hung, H. C. Chan, B. Chu, H. C. Cheng, J. Su, C. C. Tu, C. Y. Cheng, C. K. Fan
    Annals of Tropical Medicine & Parasitology.2009; 103(8): 731.     CrossRef
  • Review of Zoonotic Parasites in Medical and Veterinary Fields in the Republic of Korea
    Heejeong Youn
    The Korean Journal of Parasitology.2009; 47(Suppl): S133.     CrossRef
  • Seroprevalence of Toxoplasma gondii Infection and Characteristics of Seropositive Patients in General Hospitals in Daejeon, Korea
    Dae-Whan Shin, Dong-Yeub Cha, Quan Juan Hua, Guang-Ho Cha, Young-Ha Lee
    The Korean Journal of Parasitology.2009; 47(2): 125.     CrossRef
  • Trends in parasitic diseases in the Republic of Korea
    Eun-Hee Shin, Sang-Mee Guk, Hyo-Jin Kim, Soon-Hyung Lee, Jong-Yil Chai
    Trends in Parasitology.2008; 24(3): 143.     CrossRef
  • Evaluation of the Korean Isolate-1 Tachyzoite Antigen for Serodiagnosis of Toxoplasmosis
    Eun-Hee Shin, Dong-Hee Kim, Aifen Lin, Jo-Woon-Yi Lee, Hyo-Jin Kim, Myoung-Hee Ahn, Jong-Yil Chai
    The Korean Journal of Parasitology.2008; 46(1): 45.     CrossRef
  • Serological screening and toxoplasmosis exposure factors among pregnant women in the Democratic Republic of Sao Tome and Principe
    Chien-Ching Hung, Chia-Kwung Fan, Kua-Eyre Su, Fung-Chang Sung, Hung-Yi Chiou, Vilfrido Gil, Maria da Conceicao dos Reis Ferreira, Jose Manuel de Carvalho, Claudina Cruz, Yu-Kuan Lin, Lian-Fen Tseng, Ke-Yun Sao, Wen-Cheun Chang, Hung-Shue Lan, Shing-Hsien
    Transactions of the Royal Society of Tropical Medicine and Hygiene.2007; 101(2): 134.     CrossRef
  • Seroprevalence of Toxoplasma gondii infection among pre-schoolchildren aged 1–5 years in the Democratic Republic of Sao Tome and Principe, Western Africa
    Chia-Kwung Fan, Chien-Ching Hung, Kua-Eyre Su, Fung-Chang Sung, Hung-Yi Chiou, Vilfrido Gil, Maria da Conceicao dos Reis Ferreira, Jose Manuel de Carvalho, Claudina Cruz, Yu-Kuan Lin, Lian-Fen Tseng, Ke-Yun Sao, Wen-Cheun Chang, Hung-Shue Lan, Shing-Hsien
    Transactions of the Royal Society of Tropical Medicine and Hygiene.2006; 100(5): 446.     CrossRef
  • USE OF MONOCLONAL ANTIBODIES FOR FLOW CYTOMETRIC DETECTION OF INTRACELLULAR TOXOPLASMA GONDII IN MURINE SPLENIC LYMPHOCYTES
    Eun-Hee Shin, Sung-Bum Kim, Ho-Woo Nam, Eun-Taek Han, Jae-Hwan Park, Hye-Jin Ahn, Jong-Yil Chai
    Journal of Parasitology.2004; 90(1): 161.     CrossRef
  • Laboratory passage and characterization of an isolate of Toxoplasma gondii from an ocular patient in Korea
    Jong-Yil Chai, Aifen Lin, Eun-Hee Shin, Myoung-Don Oh, Eun-Taek Han, Ho-Woo Nam, Soon-Hyung Lee
    The Korean Journal of Parasitology.2003; 41(3): 147.     CrossRef
  • Serological evidence for remarkably variable prevalence rates of Toxoplasma gondii in children of major residential areas in United Arab Emirates
    Y.A Abu-Zeid
    Acta Tropica.2002; 83(1): 63.     CrossRef
  • Seroepidemiological study of Toxoplasma gondii infection in the rural area Okcheon-gun, Korea
    Young-Ha Lee, Hyung-Jun Noh, Ok-Sun Hwang, Sang-Keol Lee, Dae-Whan Shin
    The Korean Journal of Parasitology.2000; 38(4): 251.     CrossRef
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Two endemic foci of heterophyids and other intestinal fluke infections in southern and western coastal areas in Korea
Jong-Yil Chai, Tae-Eui Song, Eun-Taek Han, Sang-Mee Guk, Yun-Kyu Park, Min-Ho Choi, Soon-Hyung Lee
Korean J Parasitol 1998;36(3):155-161.
Published online September 30, 1998
DOI: https://doi.org/10.3347/kjp.1998.36.3.155

Two endemic foci of heterophyid infections were discovered in coastal villages of Puan-gun, Chollabuk-do, and Sachon-gun. Kyongsangnam-do, Korea. Fecal examinations were performed on 153 inhabitants of Puan-gun and 138 of Sachon-gun, using cellophane thick smear and formalin-ether sedimentation technique. The helminth egg and/or protozoan cyst positive rate was 21.5% (33/153) in Puan-gun and 39.1% (54/138) in Sachon-gun. In Puan-gun, the egg positive rate of heterophyids was the highest, 17.6%, and that of other parasites was 0.7-2.6% by parasite species. In Sachon-gun, that of heterophyids was 18.8%, followed by Clonorchis sinensis (12.3%), and other parasites (0.7-5.0%). Twenth-two (Puan-gun) and six (Sachon-gun) heterophyid egg positive cases were treated with praziquantel, and adult flukes were collected from their diarrheic stools. A total of 3,284 adult flukes of Heterophyes nocens was collected from all of the 22 patients treated in Puan-gun (3-778 individually), and other trematodes were also collected from 2-15 patients: Pygidiopsis summa, Stellantchasmus falcalus, Metagonimus yokogawai, M. miyatai, Stictodora fuscata, Heterophyopsis continua, Acanthoparyphium kurogamo, and Gymnophalloides seoi. In Sachon-gun, M. yokogawai (3,007 specimens), H. nocens (120), and S. falcatus (46) were collected from 5 of 6 treated patients, and H. continua and S. lari each from one patient. The present study revealed that heterophyid flukes, especially H. nocens and M. yokogawai, are prevalent in the southern and western coastal areas of Korea where fresh and/or brackish water fishes are popularly eaten raw.

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    The Korean Journal of Parasitology.2018; 56(3): 259.     CrossRef
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    Jong-Yil Chai, Bong-Kwang Jung
    Food and Waterborne Parasitology.2017; 8-9: 33.     CrossRef
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    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Won-Ja Lee
    The Korean Journal of Parasitology.2017; 55(4): 399.     CrossRef
  • Pygidiopsis cambodiensis n. sp. (Digenea: Heterophyidae) from experimental hamsters infected with metacercariae in mullets from Cambodia
    Woon-Mok Sohn, Deok-Gyu Kim, Bong-Kwang Jung, Jaeeun Cho, Jong-Yil Chai
    Parasitology Research.2016; 115(1): 123.     CrossRef
  • Pygidiopsis summa (Digenea: Heterophyidae): Status of Metacercarial Infection in Mullets from Coastal Areas in the Republic of Korea
    Woon-Mok Sohn, Byoung-Kuk Na, Shin-Hyeong Cho, Won-Ja Lee, Mi-Yeoun Park, Soon-Won Lee, Seung-Bong Choi, Beom-Nyung Huh, Won-Seok Seok
    The Korean Journal of Parasitology.2016; 54(4): 497.     CrossRef
  • Stellantchasmus falcatus (Digenea: Heterophyidae) in Cambodia: Discovery of Metacercariae in Mullets and Recovery of Adult Flukes in an Experimental Hamster
    Jong-Yil Chai, Woon-Mok Sohn, Byoung-Kuk Na, Hoo-Gn Jeoung, Muth Sinuon, Duong Socheat
    The Korean Journal of Parasitology.2016; 54(4): 537.     CrossRef
  • Multiplex Real-Time PCR Assay Targeting Eight Parasites Customized to the Korean Population: Potential Use for Detection in Diarrheal Stool Samples from Gastroenteritis Patients
    Eun Jeong Won, Soo Hyun Kim, Seung Jung Kee, Jong Hee Shin, Soon Pal Suh, Jong Yil Chai, Dong Wook Ryang, Myung Geun Shin, Mark Spigelman
    PLOS ONE.2016; 11(11): e0166957.     CrossRef
  • Health Risk Assessment of Cryptosporidium in Tap Water in Korea
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  • Infection Status of Estuarine Fish and Oysters with Intestinal Fluke Metacercariae in Muan-gun, Jeollanam-do, Korea
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  • Epidemiological Survey on the Infection of Intestinal Flukes in Residents of Muan-gun, Jeollanam-do, the Republic of Korea
    Shin-Hyeong Cho, Pyo-Yun Cho, Dong-Min Lee, Tong-Soo Kim, In-Sang Kim, Eun-Jung Hwang, Byoung-Kuk Na, Woon-Mok Sohn
    The Korean Journal of Parasitology.2010; 48(2): 133.     CrossRef
  • Foodborne Intestinal Flukes in Southeast Asia
    Jong-Yil Chai, Eun-Hee Shin, Soon-Hyung Lee, Han-Jong Rim
    The Korean Journal of Parasitology.2009; 47(Suppl): S69.     CrossRef
  • A survey of Heterophyes nocens and Pygidiopsis summa metacercariae in mullets and gobies along the coastal areas of the Republic of Korea
    Sang-Mee Guk, Eun-Hee Shin, Jae-Lip Kim, Woon-Mok Sohn, Kwang-Sun Hong, Cheong-Ha Yoon, Soon-Hyung Lee, Han-Jong Rim, Jong-Yil Chai
    The Korean Journal of Parasitology.2007; 45(3): 205.     CrossRef
  • A new endemic focus of Gymnophalloides seoi infection on Aphae Island, Shinan-gun, Jeollanam-do
    Jae-Hwan Park, Sang-Mee Guk, Eun-Hee Shin, Hyo-Jin Kim, Jae-Lip Kim, Min Seo, Yun-Kyu Park, Jong-Yil Chai
    The Korean Journal of Parasitology.2007; 45(1): 39.     CrossRef
  • A new endemic focus of Heterophyes nocens and other heterophyid infections in a coastal area of Gangjin-gun, Jeollanam-do
    Jae-Hwan Park, Jae-Lip Kim, Eun-Hee Shin, Sang-Mee Guk, Yun-Kyu Park, Jong-Yil Chai
    The Korean Journal of Parasitology.2007; 45(1): 33.     CrossRef
  • Prevalence of Gymnophalloides seoi infection in coastal villages of Haenam-gun and Yeongam-gun, Republic of Korea
    Sang-Mee Guk, Jae-Hwan Park, Eun-Hee Shin, Jae-Lip Kim, Aifen Lin, Jong-Yil Chai
    The Korean Journal of Parasitology.2006; 44(1): 1.     CrossRef
  • Food-borne Parasitic Diseases
    Jong-Yil Chai
    Journal of the Korean Medical Association.2004; 47(6): 496.     CrossRef
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    Jong-Yil Chai, Woon-Mok Sohn, Sung-Yil Choi, Soon-Hyung Lee
    The Korean Journal of Parasitology.2002; 40(3): 107.     CrossRef
  • Food-borne intestinal trematode infections in the Republic of Korea
    Jong-Yil Chai, Soon-Hyung Lee
    Parasitology International.2002; 51(2): 129.     CrossRef
  • Stictodora lari (Digenea: Heterophyidae): The Discovery of the First Human Infections
    J-Y. Chai, E-T. Han, Y-K. Park, S-M. Guk, J-H. Park, S-H. Lee
    Journal of Parasitology.2002; 88(3): 627.     CrossRef
  • Intestinal histopathology and in situ postures of Gymnophalloides seoi in experimentally infected mice
    Jong-Yil Chai, Hong-Soon Lee, Sung-Jong Hong, Jae Hyung Yoo, Sang-Mee Guk, Min Seo, Min-Ho Choi, Soon-Hyung Lee
    The Korean Journal of Parasitology.2001; 39(1): 31.     CrossRef
  • A nationwide survey of the prevalence of human Gymnophalloides seoi infection on western and southern coastal islands in the Republic of Korea
    Jong-Yil Chai, Jae-Hwan Park, Eun-Taek Han, Eun-Hee Shin, Jae-Lip Kim, Kwang-Seon Hong, Han-Jong Rim, Soon-Hyung Lee
    The Korean Journal of Parasitology.2001; 39(1): 23.     CrossRef
  • A review of Gymnophalloides seoi (Digenea: Gymnophallidae) and human infections in the Republic of Korea
    Soon-Hyung Lee, Jong-Yil Chai
    The Korean Journal of Parasitology.2001; 39(2): 85.     CrossRef
  • High endemicity of Metagonimus yokogawai infection among residents of Samchok-shi, Kangwon-do
    Jong-Yil Chai, Eun-Taek Han, Yun-Kyu Park, Sang-Mee Guk, Jae-Lip Kim, Soon-Hyung Lee
    The Korean Journal of Parasitology.2000; 38(1): 33.     CrossRef
  • Persistent endemicity of Gymnophalloides seoi infection in a southwestern coastal village of Korea with special reference to its egg laying capacity in the human host
    Jong-Yil Chai, Geun Chan Lee, Yun-Kyu Park, Eun-Taek Han, Min Seo, Jin Kim, Sang-Mee Guk, Eun-Hee Shin, Min-Ho Choi, Soon-Hyung Lee
    The Korean Journal of Parasitology.2000; 38(2): 51.     CrossRef
  • An incidental case of human Heterophyes nocens infection diagnosed by sectional morphology in a biopsy specimen of the small intestine
    Yong-Suk Ryang, Chi-Young Lee, Kyu-Jae Lee, Soon-Hyung Lee, Jong-Yil Chai
    The Korean Journal of Parasitology.1999; 37(3): 189.     CrossRef
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  • Crossref